Alain Dagher
@alaindagher.bsky.social
Neurology and brain imaging.
ORCID: 0000-0002-0945-5779
ORCID: 0000-0002-0945-5779
Pinned
Reposted by Alain Dagher
Happy to share our review "Investigating hierarchical critical periods in human neurodevelopment” in @npp-journal.bsky.social! We examine neurobiological, environmental & behavioral evidence for human critical periods in sensory and association cortex +discuss new research directions rdcu.be/eMkVU 🧵
November 11, 2025 at 8:01 PM
Happy to share our review "Investigating hierarchical critical periods in human neurodevelopment” in @npp-journal.bsky.social! We examine neurobiological, environmental & behavioral evidence for human critical periods in sensory and association cortex +discuss new research directions rdcu.be/eMkVU 🧵
When they came after young women wearing a hijab, Lionel Carmant said nothing because his daughter does not wear a hijab. www.cbc.ca/news/canada/...
Quebec bill would extend religious symbols ban to school support workers, force students to uncover faces | CBC News
The Quebec government is putting forward a bill that would extend the province's ban on the wearing of religious symbols to support staff in schools, and prohibit students from having their faces cove...
www.cbc.ca
October 31, 2025 at 5:30 PM
When they came after young women wearing a hijab, Lionel Carmant said nothing because his daughter does not wear a hijab. www.cbc.ca/news/canada/...
Reposted by Alain Dagher
🚨New in Lancet Neurology: Autopsy study of aducanumab in #Alzheimer’s shows superficial cortical Aβ cleared, but deeper persists. ARIA showed inflammation+ microinfarcts in leptomeningeal/penetrating vessels. Some path is PET-invisible. @drneurochic.bsky.social
authors.elsevier.com/a/1lxn85FFzL...
authors.elsevier.com/a/1lxn85FFzL...
October 16, 2025 at 10:33 AM
🚨New in Lancet Neurology: Autopsy study of aducanumab in #Alzheimer’s shows superficial cortical Aβ cleared, but deeper persists. ARIA showed inflammation+ microinfarcts in leptomeningeal/penetrating vessels. Some path is PET-invisible. @drneurochic.bsky.social
authors.elsevier.com/a/1lxn85FFzL...
authors.elsevier.com/a/1lxn85FFzL...
I have really enjoyed this book.
October 16, 2025 at 6:39 PM
I have really enjoyed this book.
Reposted by Alain Dagher
In 2018, Charles Murray challenged me to a bet: "We will understand IQ genetically—I think most of the picture will have been filled in by 2025—there will still be blanks—but we’ll know basically what’s going on." It's now 2025, and I claim a win. I write about it in The Atlantic.
Your Genes Are Simply Not Enough to Explain How Smart You Are
Seven years ago, I took a bet with Charles Murray about whether we’d basically understand the genetics of intelligence by now.
www.theatlantic.com
October 13, 2025 at 1:33 PM
In 2018, Charles Murray challenged me to a bet: "We will understand IQ genetically—I think most of the picture will have been filled in by 2025—there will still be blanks—but we’ll know basically what’s going on." It's now 2025, and I claim a win. I write about it in The Atlantic.
Francois Legault and Simon Jolin-Barrette are vying to become the Thomas Jefferson and Benjamin Franklin of Quebec.
www.cbc.ca/news/canada/...
www.cbc.ca/news/canada/...
Quebec tables draft constitution to affirm its 'distinct national character,' premier says | CBC News
The constitution, filed at the National Assembly on Thursday and lambasted by opposition parties as a piece of political theatre filed without proper consultation, includes language asserting Quebec’s...
www.cbc.ca
October 10, 2025 at 1:24 PM
Francois Legault and Simon Jolin-Barrette are vying to become the Thomas Jefferson and Benjamin Franklin of Quebec.
www.cbc.ca/news/canada/...
www.cbc.ca/news/canada/...
I hate this place.
October 8, 2025 at 8:39 PM
I hate this place.
Reposted by Alain Dagher
Excited to share that our work introducing the Reproducible Brain Charts (RBC) data resource is now published in Neuron!! 🎉
📚 Read the paper: authors.elsevier.com/c/1lpaF3BtfH...
🧠 Explore the RBC dataset: reprobrainchart.github.io
📚 Read the paper: authors.elsevier.com/c/1lpaF3BtfH...
🧠 Explore the RBC dataset: reprobrainchart.github.io
(1/18) Now out on BioRxiv‼️ Reproducible Brain Charts: An open data resource for mapping brain development and its associations with mental health | doi.org/10.1101/2025...
Funded by National Institute of Mental Health (NIMH)
Funded by National Institute of Mental Health (NIMH)
Reproducible Brain Charts: An open data resource for mapping brain development and its associations with mental health
Major mental disorders are increasingly understood as disorders of brain development. Large and heterogeneous samples are required to define generalizable links between brain development and psychopat...
doi.org
September 22, 2025 at 9:51 PM
Excited to share that our work introducing the Reproducible Brain Charts (RBC) data resource is now published in Neuron!! 🎉
📚 Read the paper: authors.elsevier.com/c/1lpaF3BtfH...
🧠 Explore the RBC dataset: reprobrainchart.github.io
📚 Read the paper: authors.elsevier.com/c/1lpaF3BtfH...
🧠 Explore the RBC dataset: reprobrainchart.github.io
Reposted by Alain Dagher
📅 Save the Date: Oxford 2026 Glymphatic Research Symposium!
• Dates: March 30th, March 31st, April 1st 2026.
• Keynote speakers: Maiken Nedergaard & Jonathan Kipnis.
• Venue: Keble College, Oxford, UK.
• Registration link to follow
Looking forward to seeing you there! 🧠
• Dates: March 30th, March 31st, April 1st 2026.
• Keynote speakers: Maiken Nedergaard & Jonathan Kipnis.
• Venue: Keble College, Oxford, UK.
• Registration link to follow
Looking forward to seeing you there! 🧠
September 12, 2025 at 2:59 PM
📅 Save the Date: Oxford 2026 Glymphatic Research Symposium!
• Dates: March 30th, March 31st, April 1st 2026.
• Keynote speakers: Maiken Nedergaard & Jonathan Kipnis.
• Venue: Keble College, Oxford, UK.
• Registration link to follow
Looking forward to seeing you there! 🧠
• Dates: March 30th, March 31st, April 1st 2026.
• Keynote speakers: Maiken Nedergaard & Jonathan Kipnis.
• Venue: Keble College, Oxford, UK.
• Registration link to follow
Looking forward to seeing you there! 🧠
How can one volunteer?
www.montrealgazette.com/news/provinc...
www.montrealgazette.com/news/provinc...
McGill University to open ‘satellite campuses’ outside Canada, president says
Deep Saini framed the planned satellite operations as an extension of McGill’s Quebec base, describing the university as “a locally anchored, globally pre-eminent university.”
www.montrealgazette.com
September 17, 2025 at 11:30 PM
How can one volunteer?
www.montrealgazette.com/news/provinc...
www.montrealgazette.com/news/provinc...
Reposted by Alain Dagher
Network spreading and local biological vulnerability in amyotrophic lateral sclerosis |
doi.org/10.1038/s420...
How do brain network structure and local biological features shape the spatial patterning of atrophy in ALS? @asafarahani.bsky.social investigates ⤵️
doi.org/10.1038/s420...
How do brain network structure and local biological features shape the spatial patterning of atrophy in ALS? @asafarahani.bsky.social investigates ⤵️
September 16, 2025 at 4:17 PM
Network spreading and local biological vulnerability in amyotrophic lateral sclerosis |
doi.org/10.1038/s420...
How do brain network structure and local biological features shape the spatial patterning of atrophy in ALS? @asafarahani.bsky.social investigates ⤵️
doi.org/10.1038/s420...
How do brain network structure and local biological features shape the spatial patterning of atrophy in ALS? @asafarahani.bsky.social investigates ⤵️
Reposted by Alain Dagher
Huge thanks to Sanjay Kalra and the CALSNIC team, J Hansen, @vincebaz.bsky.social @goliashf.bsky.social L Collins @dadarmahsa.bsky.social @alaindagher.bsky.social !!
code: github.com/netneurolab/...
code: github.com/netneurolab/...
GitHub - netneurolab/Farahani_ALS: Network spreading and local biological vulnerability in amyotrophic lateral sclerosis
Network spreading and local biological vulnerability in amyotrophic lateral sclerosis - netneurolab/Farahani_ALS
github.com
September 16, 2025 at 4:17 PM
Huge thanks to Sanjay Kalra and the CALSNIC team, J Hansen, @vincebaz.bsky.social @goliashf.bsky.social L Collins @dadarmahsa.bsky.social @alaindagher.bsky.social !!
code: github.com/netneurolab/...
code: github.com/netneurolab/...
Reposted by Alain Dagher
The effect of spherical projections on spin tests for brain maps | doi.org/10.1162/IMAG...
Spin tests are the de facto null model for map-to-map comparisons in brain imaging. Why don't they perfectly control false positives? @vincebaz.bsky.social explores ⤵️
Spin tests are the de facto null model for map-to-map comparisons in brain imaging. Why don't they perfectly control false positives? @vincebaz.bsky.social explores ⤵️
September 10, 2025 at 1:07 PM
The effect of spherical projections on spin tests for brain maps | doi.org/10.1162/IMAG...
Spin tests are the de facto null model for map-to-map comparisons in brain imaging. Why don't they perfectly control false positives? @vincebaz.bsky.social explores ⤵️
Spin tests are the de facto null model for map-to-map comparisons in brain imaging. Why don't they perfectly control false positives? @vincebaz.bsky.social explores ⤵️
Reposted by Alain Dagher
New paper in Imaging Neuroscience by Malte R. Güth, Travis E. Baker, et al:
Right posterior theta reflects human parahippocampal phase resetting by salient cues during goal-directed navigation
doi.org/10.1162/IMAG...
Right posterior theta reflects human parahippocampal phase resetting by salient cues during goal-directed navigation
doi.org/10.1162/IMAG...
September 10, 2025 at 5:41 AM
New paper in Imaging Neuroscience by Malte R. Güth, Travis E. Baker, et al:
Right posterior theta reflects human parahippocampal phase resetting by salient cues during goal-directed navigation
doi.org/10.1162/IMAG...
Right posterior theta reflects human parahippocampal phase resetting by salient cues during goal-directed navigation
doi.org/10.1162/IMAG...
Reposted by Alain Dagher
This important new study in Movement Disorders looked at folks w/ REM sleep behavior disorder, a common early sign of Parkinson’s. The results suggest that fMRI may reveal changes in brain networks long before symptoms of PD or dementia w/ Lewy bodies fully emerge. @parkinsondotorg.bsky.social
September 4, 2025 at 11:43 AM
This important new study in Movement Disorders looked at folks w/ REM sleep behavior disorder, a common early sign of Parkinson’s. The results suggest that fMRI may reveal changes in brain networks long before symptoms of PD or dementia w/ Lewy bodies fully emerge. @parkinsondotorg.bsky.social
Reposted by Alain Dagher
Companies charging and people paying up to $500,000 to select embryos with high IQ potential, even though that isn't possible. No less ethical.
"Current models explain about 5% to 10% of the differences in cognitive ability between people"
Front page WSJ today www.wsj.com/us-news/sili...
"Current models explain about 5% to 10% of the differences in cognitive ability between people"
Front page WSJ today www.wsj.com/us-news/sili...
August 14, 2025 at 6:28 PM
Companies charging and people paying up to $500,000 to select embryos with high IQ potential, even though that isn't possible. No less ethical.
"Current models explain about 5% to 10% of the differences in cognitive ability between people"
Front page WSJ today www.wsj.com/us-news/sili...
"Current models explain about 5% to 10% of the differences in cognitive ability between people"
Front page WSJ today www.wsj.com/us-news/sili...
Reposted by Alain Dagher
2. When I give seminars about this, I ask my (professional scientist) audience "How many of you believe that anthropogenic climate change is real?"
Almost all hands raise.
I then ask "How many of you have read the IPCC report or equivalent"
Fewer than 25% of hands raise.
Almost all hands raise.
I then ask "How many of you have read the IPCC report or equivalent"
Fewer than 25% of hands raise.
August 12, 2025 at 4:50 AM
2. When I give seminars about this, I ask my (professional scientist) audience "How many of you believe that anthropogenic climate change is real?"
Almost all hands raise.
I then ask "How many of you have read the IPCC report or equivalent"
Fewer than 25% of hands raise.
Almost all hands raise.
I then ask "How many of you have read the IPCC report or equivalent"
Fewer than 25% of hands raise.
Yesterday I decided to become a Samsung phone user. Today I am a separatist. Never say never! 😀
globalnews.ca/news/1132233...
globalnews.ca/news/1132233...
Separatist group applies to have review of Alberta referendum question quashed | Globalnews.ca
A court in Edmonton is being asked Thursday whether a proposed referendum question on Alberta separation would be a violation of the Canadian constitution.
globalnews.ca
August 7, 2025 at 11:29 PM
Yesterday I decided to become a Samsung phone user. Today I am a separatist. Never say never! 😀
globalnews.ca/news/1132233...
globalnews.ca/news/1132233...
Reposted by Alain Dagher
How does cerebral #BloodPerfusion map onto micro-, meso- & macro-scale brain structure? @asafarahani.bsky.social @misicbata.bsky.social &co characterize blood perfusion in the #HumanBrain, revealing how it changes with age & in #NeurodegenerativeDisease @plosbiology.org 🧪 plos.io/46AEURS
July 31, 2025 at 5:09 PM
How does cerebral #BloodPerfusion map onto micro-, meso- & macro-scale brain structure? @asafarahani.bsky.social @misicbata.bsky.social &co characterize blood perfusion in the #HumanBrain, revealing how it changes with age & in #NeurodegenerativeDisease @plosbiology.org 🧪 plos.io/46AEURS
Reposted by Alain Dagher
Integrating and interpreting brain maps | doi.org/10.1016/j.ti...
Imaging and recording technologies make it possible to map multiple biological features of the brain. How can these features be conceptually integrated into a coherent understanding of brain structure and function? ⤵️
Imaging and recording technologies make it possible to map multiple biological features of the brain. How can these features be conceptually integrated into a coherent understanding of brain structure and function? ⤵️
August 4, 2025 at 2:27 PM
Integrating and interpreting brain maps | doi.org/10.1016/j.ti...
Imaging and recording technologies make it possible to map multiple biological features of the brain. How can these features be conceptually integrated into a coherent understanding of brain structure and function? ⤵️
Imaging and recording technologies make it possible to map multiple biological features of the brain. How can these features be conceptually integrated into a coherent understanding of brain structure and function? ⤵️
"The Quebec government has served the school with fines totalling almost $30 million for violating the province’s language law by admitting too many students to its English-taught continuing-education programs over the last two years."
Read more at: www.montrealgazette.com/news/article...
Read more at: www.montrealgazette.com/news/article...
LaSalle College says it helps French thrive, so why is Quebec cracking down on it?
Instead of punishing the school, the CAQ government should be using it as a model for francization and the principle of harmonious “vivre ensemble,” the school’s president and CEO says.
www.montrealgazette.com
July 23, 2025 at 3:02 PM
"The Quebec government has served the school with fines totalling almost $30 million for violating the province’s language law by admitting too many students to its English-taught continuing-education programs over the last two years."
Read more at: www.montrealgazette.com/news/article...
Read more at: www.montrealgazette.com/news/article...
Reposted by Alain Dagher
In collab with @alaindagher.bsky.social @misicbata.bsky.social and Shady Rahayel, we used the SIR model to computationally model neurodegenration as a function of the structural connectome and gene expression. SIR cpatures the dynamics better than axonal connectivity (very bad!) and gene expression!
July 22, 2025 at 6:00 PM
In collab with @alaindagher.bsky.social @misicbata.bsky.social and Shady Rahayel, we used the SIR model to computationally model neurodegenration as a function of the structural connectome and gene expression. SIR cpatures the dynamics better than axonal connectivity (very bad!) and gene expression!
Reposted by Alain Dagher
On the root cause of global obesity
www.pnas.org/doi/suppl/10...
www.science.org/content/arti...
www.washingtonpost.com/wellness/202...
www.pnas.org/doi/suppl/10...
www.science.org/content/arti...
www.washingtonpost.com/wellness/202...
Energy expenditure and obesity across the economic spectrum | PNAS
Global economic development has been associated with an increased prevalence of obesity
and related health problems. Increased caloric intake and r...
www.pnas.org
July 15, 2025 at 1:54 PM
On the root cause of global obesity
www.pnas.org/doi/suppl/10...
www.science.org/content/arti...
www.washingtonpost.com/wellness/202...
www.pnas.org/doi/suppl/10...
www.science.org/content/arti...
www.washingtonpost.com/wellness/202...
Reposted by Alain Dagher
Excited to announce my new book FOOD INTELLIGENCE coauthored with brilliant journalist @juliabelluz.bsky.social! Cutting through the confusion about diet & health, #FoodIntelligence describes the fascinating science of how food both nourishes & harms us. www.penguinrandomhouse.com/books/671334...
Food Intelligence by Julia Belluz, Kevin Hall, PhD: 9780593332306 | PenguinRandomHouse.com: Books
The essential guide for understanding what you’re eating, and the forces that are driving you to eat it. Nutrition isn’t rocket science; it’s harder. There are new diet fads, bold...
www.penguinrandomhouse.com
July 16, 2025 at 9:53 AM
Excited to announce my new book FOOD INTELLIGENCE coauthored with brilliant journalist @juliabelluz.bsky.social! Cutting through the confusion about diet & health, #FoodIntelligence describes the fascinating science of how food both nourishes & harms us. www.penguinrandomhouse.com/books/671334...
Reposted by Alain Dagher
Hi everyone! Blue Sky seems alright!
Check out our massive new review on Coenzyme Q that earned the cover 😉.
Check out our massive new review on Coenzyme Q that earned the cover 😉.
November 29, 2024 at 2:46 PM
Hi everyone! Blue Sky seems alright!
Check out our massive new review on Coenzyme Q that earned the cover 😉.
Check out our massive new review on Coenzyme Q that earned the cover 😉.