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alainamstutz.bsky.social
Alain Amstutz | Ts'epo
@alainamstutz.bsky.social
69 followers 260 following 1 posts
MD PhD | Trying to bridge the gap between trialist and epidemiologist | Jazz piano enthusiast | Keen on understanding Alkebulan History
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Reposted by Alain Amstutz | Ts'epo
clinepi-basel.bsky.social
💇🏾‍♀️ New publication from our team: Hair Salons as a promising space to provide HIV & Sexual and SRH services for young women in Lesotho

💭 The team is currently looking for funding to implement a pilot - ideas welcome!

Read more here: bmcpublichealth.biomedcentral.com/articles/10....
Hair salons as a promising space to provide HIV and sexual and reproductive health services for young women in Lesotho: a citizen scientist mixed-methods study - BMC Public Health
Introduction Adolescent girls and young women in southern Africa are disproportionately affected by HIV and sexual and reproductive health (SRH) challenges. There is a need for more accessible and de-...
bmcpublichealth.biomedcentral.com
July 8, 2025 at 7:11 PM
Reposted by Alain Amstutz | Ts'epo
clinepi-basel.bsky.social
With over 96% of global trial data on this topic included, this #IPDMA, published in @lancetrespirmed.bsky.social and initiated by #EU-RESPONSE, provides the most comprehensive analysis for JAK inhibitors for adults hospitalized due to #COVID19.

Full article: www.thelancet.com/journals/lan...
Effects of Janus kinase inhibitors in adults admitted to hospital due to COVID-19: a systematic review and individual participant data meta-analysis of randomised clinical trials
This IPDMA of RCTs in adults admitted to hospital due to COVID-19 found that JAK inhibitors reduced mortality across all levels of respiratory support, independent of dexamethasone or tocilizumab, and...
www.thelancet.com
May 15, 2025 at 6:15 AM
Reposted by Alain Amstutz | Ts'epo
lancetrespirmed.bsky.social
📰 New Article: Effects of Janus kinase inhibitors in adults admitted to hospital with #COVID19: a systematic review and IPD meta-analysis of randomised clinical trials

Findings suggested that JAK inhibitors reduced mortality across all levels of respiratory support

🔗 tinyurl.com/2hprv99v
Research in context panel: "Our IPDMA presents the most comprehensive summary of all existing randomised evidence (including >96% of participants recruited globally on the topic) and subgroup analyses settling the issue of discordant guidelines. JAK inhibitors seem a safe and efficacious treatment option for adults hospitalised with COVID-19 when given in addition to usual care."
May 14, 2025 at 1:56 PM
Reposted by Alain Amstutz | Ts'epo
pippa-matt.bsky.social
"Get the experts into the room, and get a plan together...We don’t need perfection, but we do need urgency. The health system that is delivering HIV care is unravelling now.
The cost of doing nothing is millions of lives and a shattered legacy." @francoisventer.bsky.social
Our HIV programme is collapsing — and our government is nowhere to be seen
But urgent action can save us
groundup.org.za
April 23, 2025 at 9:39 AM
alainamstutz.bsky.social
Causal understanding is not a point of view, it’s a point of do - what a beautifully written essay by @marielgoddu.bsky.social: aeon.co/essays/causa...
Causal understanding is not a point of view, it’s a point of do | Aeon Essays
Humans have a superpower that makes us uniquely capable of controlling the world: our ability to understand cause and effect
aeon.co
March 23, 2025 at 4:40 PM
Reposted by Alain Amstutz | Ts'epo
qmul.bsky.social
Delighted to see Prof @profchloeorkin.bsky.social, Director @shareeastlondon.bsky.social & Consultant HIV physician at Barts Health, profiled in @thelancet.bsky.social today. Great to learn more about her career, with ‘equality at its heart, motivated by activism’ www.thelancet.com/journals/lan...
Chloe Orkin: forefronting social justice in medicine
HIV researcher and physician Chloe Orkin, Professor of Infection and Inequities at Queen Mary University of London, UK, embarked on her career at the age of just 16 years when she began her medical de...
www.thelancet.com
January 31, 2025 at 10:25 AM
Reposted by Alain Amstutz | Ts'epo
clinepi-basel.bsky.social
Data sharing is a big hurdle in Individual Participant Data Mata Analysis (#IPDMA).
Matthias Briel and @alainamstutz.bsky.social participated at a EOSC-ENTRUST workshop to address this problem.

More: ecrin.org/news/eosc-en...

@ecrin.bsky.social #UniversityofOslo
#HealthDataResearchUK
January 31, 2025 at 11:12 AM
Reposted by Alain Amstutz | Ts'epo
marionkcampbell.bsky.social
An issue that often comes up is how to set a “non-inferiority margin” in a non-inferiority trial and how to ensure it is appropriate 1/8
#MethodologyMonday #109
January 27, 2025 at 7:32 AM