My favorite effect is that each channel "sees" its own effect on the membrane voltage, so the statistics of spontaneous gating events become totally different. There are long-lived single-channel memory effects, mediated by membrane voltage.

Now that it's realistic to think about imaging voltage in small structures, we need a theory to go along with the data. This preprint is a first attempt at this.

Yes, and mine is terminated because we're trying to punish antisemites. Kafka couldn't do better if he tried.

Led by Nate Lord, with @harrymcnamara.bsky.social, Alison Guyer, Bill Jia, Vicente Parot, Caleb Dobbs, and Alex Schier.

Yeah, there's a thin ring btwn the coarse focus knob and the microscope body. On one side of the microscope this sets the upper limit to the focus, the other side sets the friction in the focus train. Increase the friction.

Discussing the findings in our recent paper on dendritic voltage imaging in acute brain slices:
www.nature.com/articles/s41...

Sure. Easy to map potentiated spine density across space. If the expression density is high, the challenge is to trace from the spines along the dendrites back to the parent cell. That would require some sort of high resolution connectomics. Totally plausible, but that would be a project.