Andrii Bugai
@abugai.bsky.social
Scientist at Aarhus University (DK).
Alumni of the University of Helsinki (FI) and Kharkiv University (UA).
I study how genes are regulated at the level of RNA.
Alumni of the University of Helsinki (FI) and Kharkiv University (UA).
I study how genes are regulated at the level of RNA.
RP
ZAKα is a sensor of mRNA stasis at the ribosomal exit channel https://www.biorxiv.org/content/10.1101/2025.11.22.689755v1
November 28, 2025 at 7:55 PM
RP
Onions Nebula finally back
October 31, 2025 at 6:03 PM
Onions Nebula finally back
Reposted by Andrii Bugai
Thrilled to share that I’ll be joining @imbmainz.bsky.social in February 2026 to start my own group!
We will explore new mechanisms in eukaryotic gene expression, leveraging ‘evolutionary play’ to uncover how regulation, repurposing, and hijacking shape RNA biology.
PhD positions available!
We will explore new mechanisms in eukaryotic gene expression, leveraging ‘evolutionary play’ to uncover how regulation, repurposing, and hijacking shape RNA biology.
PhD positions available!
October 12, 2025 at 8:19 PM
Thrilled to share that I’ll be joining @imbmainz.bsky.social in February 2026 to start my own group!
We will explore new mechanisms in eukaryotic gene expression, leveraging ‘evolutionary play’ to uncover how regulation, repurposing, and hijacking shape RNA biology.
PhD positions available!
We will explore new mechanisms in eukaryotic gene expression, leveraging ‘evolutionary play’ to uncover how regulation, repurposing, and hijacking shape RNA biology.
PhD positions available!
Choose your cluster...
October 12, 2025 at 8:52 PM
Choose your cluster...
October's colours of the Moon
October 1, 2025 at 8:12 PM
October's colours of the Moon
Check the highlights of our recent nuclear RNA sorting story here:
How are RNAs sorted for export vs. degradation in the nucleus? In collaboration with @heick.bsky.social’s lab we (@clemensplaschka.bsky.social and @juliusbrennecke.bsky.social labs) discovered a direct mechanistic link between the export and decay machineries: www.biorxiv.org/content/10.1... (1/x)
Molecular basis of polyadenylated RNA fate determination in the nucleus
Eukaryotic genomes generate a plethora of polyadenylated (pA+) RNAs[1][1],[2][2], that are packaged into ribonucleoprotein particles (RNPs). To ensure faithful gene expression, functional pA+ RNPs, in...
www.biorxiv.org
September 23, 2025 at 7:08 AM
Check the highlights of our recent nuclear RNA sorting story here:
Images from summer. Part 3.
September 19, 2025 at 7:51 PM
Images from summer. Part 3.
This one is prettier than Andromeda.
September 19, 2025 at 7:47 PM
This one is prettier than Andromeda.
Images of summer. Part 1.
September 19, 2025 at 7:45 PM
Images of summer. Part 1.
Reposted by Andrii Bugai
Love RNA biology?
Join us to explore the piRNA pathway with structural and genetic approaches (see 👇👇).
PhD student/postdoc position co-supervised by Clemens Plaschka & myself.
DM or email us if you’d like to know more!
@vbcscitraining.bsky.social @imbavienna.bsky.social @impvienna.bsky.social
Join us to explore the piRNA pathway with structural and genetic approaches (see 👇👇).
PhD student/postdoc position co-supervised by Clemens Plaschka & myself.
DM or email us if you’d like to know more!
@vbcscitraining.bsky.social @imbavienna.bsky.social @impvienna.bsky.social
PIWI clade Argonautes are essential for transposon silencing. Without them, animals are sterile due to massive transposon activity.
But how does piRNA-guided target interaction translate into silencing?
PhD student Júlia Portell Montserrat has an intriguing answer
www.cell.com/molecular-ce...
But how does piRNA-guided target interaction translate into silencing?
PhD student Júlia Portell Montserrat has an intriguing answer
www.cell.com/molecular-ce...
September 18, 2025 at 2:34 PM
Love RNA biology?
Join us to explore the piRNA pathway with structural and genetic approaches (see 👇👇).
PhD student/postdoc position co-supervised by Clemens Plaschka & myself.
DM or email us if you’d like to know more!
@vbcscitraining.bsky.social @imbavienna.bsky.social @impvienna.bsky.social
Join us to explore the piRNA pathway with structural and genetic approaches (see 👇👇).
PhD student/postdoc position co-supervised by Clemens Plaschka & myself.
DM or email us if you’d like to know more!
@vbcscitraining.bsky.social @imbavienna.bsky.social @impvienna.bsky.social
Check out our latest preprint, focusing on how nuclear decay and export compete for poly(A)+ RNAs utilizing the same biochemical mechanism.
Molecular basis of polyadenylated RNA fate determination in the nucleus https://www.biorxiv.org/content/10.1101/2025.09.16.676470v1
September 17, 2025 at 10:51 AM
Check out our latest preprint, focusing on how nuclear decay and export compete for poly(A)+ RNAs utilizing the same biochemical mechanism.
Limited sleep on starry nights...
May 13, 2025 at 8:03 AM
Limited sleep on starry nights...
Reposted by Andrii Bugai
“Many” Ukrainian civilians killed in a Russian ballistic missile strike on Sumy as residents were heading to church for Palm Sunday services, local officials say. One of the missiles apparently hit a trolley bus.
In other news, Witkoff’s sightseeing in St Petersburg seems to have gone great.
In other news, Witkoff’s sightseeing in St Petersburg seems to have gone great.
April 13, 2025 at 8:14 AM
“Many” Ukrainian civilians killed in a Russian ballistic missile strike on Sumy as residents were heading to church for Palm Sunday services, local officials say. One of the missiles apparently hit a trolley bus.
In other news, Witkoff’s sightseeing in St Petersburg seems to have gone great.
In other news, Witkoff’s sightseeing in St Petersburg seems to have gone great.
Reposted by Andrii Bugai
A world paralyzed by indifference, watching in silence as Russia slaughters civilians in Ukraine—year after year.
“Many” Ukrainian civilians killed in a Russian ballistic missile strike on Sumy as residents were heading to church for Palm Sunday services, local officials say. One of the missiles apparently hit a trolley bus.
In other news, Witkoff’s sightseeing in St Petersburg seems to have gone great.
In other news, Witkoff’s sightseeing in St Petersburg seems to have gone great.
April 13, 2025 at 8:32 AM
A world paralyzed by indifference, watching in silence as Russia slaughters civilians in Ukraine—year after year.
March 29, 2025 at 11:35 AM
Nebulae, Orion constellation
March 22, 2025 at 6:39 PM
Nebulae, Orion constellation
March 22, 2025 at 6:35 PM
First attempts with new toys...
March 14, 2025 at 8:24 PM
First attempts with new toys...
Reposted by Andrii Bugai
It’s now undeniably clear that Trump is attempting to blackmail Ukraine into making concessions to the aggressor.This is a critical moment for democracies —either they unite against rising autocracies, or risk a future shaped by authoritarian power and aggression
www.theguardian.com/world/2025/m...
www.theguardian.com/world/2025/m...
US has suspended all military aid to Ukraine, White House official says, in wake of Trump-Zelenskyy row
Decision affects ammunition, vehicles and other equipment including weapons in transit
www.theguardian.com
March 4, 2025 at 6:57 AM
It’s now undeniably clear that Trump is attempting to blackmail Ukraine into making concessions to the aggressor.This is a critical moment for democracies —either they unite against rising autocracies, or risk a future shaped by authoritarian power and aggression
www.theguardian.com/world/2025/m...
www.theguardian.com/world/2025/m...
Reposted by Andrii Bugai
And it is downright foolish to think that the Vietnamese could ever have defeated the USA or the Afghans have defeated the USSR!
We live in an age where policy makers wear their ignorance proudly.
We live in an age where policy makers wear their ignorance proudly.
February 2, 2025 at 8:10 AM
And it is downright foolish to think that the Vietnamese could ever have defeated the USA or the Afghans have defeated the USSR!
We live in an age where policy makers wear their ignorance proudly.
We live in an age where policy makers wear their ignorance proudly.
First auroras of the year!
February 1, 2025 at 6:29 PM
First auroras of the year!