Aaron Ring
@aaronmring.bsky.social
Associate Professor and Anderson Family Chair of Immunotherapy, Fred Hutchinson Cancer Center
Studying #cytokines, (auto)antibodies, and #cancerimmunotherapy.
Founder: Simcha Tx, Seranova Bio, & Stipple Bio
Studying #cytokines, (auto)antibodies, and #cancerimmunotherapy.
Founder: Simcha Tx, Seranova Bio, & Stipple Bio
You're welcome! Let me know if you need any help setting up a project.
April 30, 2025 at 4:39 AM
You're welcome! Let me know if you need any help setting up a project.
Ready to start designing some proteins? The door’s open at ariax.bio. If you have question or feedback, please drop a reply or hop in our Discord (discord.com/invite/Q7SnV...).
Ariax.bio - Democratizing Protein Design
Computationally design de novo protein binders with BindCraft and instant GPU access. No queues, no quotas, and no strings attached.
ariax.bio
April 29, 2025 at 9:27 PM
Ready to start designing some proteins? The door’s open at ariax.bio. If you have question or feedback, please drop a reply or hop in our Discord (discord.com/invite/Q7SnV...).
Cost? A typical 100-binder miniprotein design run takes 24–72 GPU-hours. That ends up being ~$100–$500 depending on the size of your target and design settings. Compare that to a mouse hybridoma campaign at a CRO, which can cost >$10,000 and drag on for months.
April 29, 2025 at 9:27 PM
Cost? A typical 100-binder miniprotein design run takes 24–72 GPU-hours. That ends up being ~$100–$500 depending on the size of your target and design settings. Compare that to a mouse hybridoma campaign at a CRO, which can cost >$10,000 and drag on for months.
Here is what it looks in action. From the landing page, you can start designing in under a minute. It took just 52 seconds for this job to create miniprotein antagonists against CD122 (IL2Rβ).
April 29, 2025 at 9:27 PM
Here is what it looks in action. From the landing page, you can start designing in under a minute. It took just 52 seconds for this job to create miniprotein antagonists against CD122 (IL2Rβ).
Ariax removes that friction. Open the site, fill in a short form, and click start. We spin up a GPU in seconds, stream results back to a private cloud folder, and shut everything down when the job’s done. You only pay for compute—about 40 % less than AWS.
April 29, 2025 at 9:27 PM
Ariax removes that friction. Open the site, fill in a short form, and click start. We spin up a GPU in seconds, stream results back to a private cloud folder, and shut everything down when the job’s done. You only pay for compute—about 40 % less than AWS.
Still, for many researchers, these incredible tools are out of reach. They use powerful GPUs that most of us don’t have and complex command-line gymnastics over SSH.
April 29, 2025 at 9:27 PM
Still, for many researchers, these incredible tools are out of reach. They use powerful GPUs that most of us don’t have and complex command-line gymnastics over SSH.
BindCraft deserves special credit. @martinpacesa.bsky.social in Bruno Correia's group stitched the whole pipeline together: hallucinate, refine, score. It keeps winning Adaptyv Bio's design challenges and has become the go-to in my own lab. That’s the engine inside Ariax.
April 29, 2025 at 9:27 PM
BindCraft deserves special credit. @martinpacesa.bsky.social in Bruno Correia's group stitched the whole pipeline together: hallucinate, refine, score. It keeps winning Adaptyv Bio's design challenges and has become the go-to in my own lab. That’s the engine inside Ariax.
Computational protein design capabilities have exploded over the past few years. Tools like RFdiffusion, ProteinMPNN, ColabDesign, and BindCraft have changed the game. Success rates for miniprotein binder campaigns now approach 100%.
April 29, 2025 at 9:27 PM
Computational protein design capabilities have exploded over the past few years. Tools like RFdiffusion, ProteinMPNN, ColabDesign, and BindCraft have changed the game. Success rates for miniprotein binder campaigns now approach 100%.
Welcome Scott! Good to see another TST colleague from @fredhutch.bsky.social here.
November 19, 2024 at 7:04 PM
Welcome Scott! Good to see another TST colleague from @fredhutch.bsky.social here.
I'm with Jony on this... I miss early Twitter when the feed was 100% cool science. It was such a cheat code! I hope bluesky can recreate that vibe. OFC if we want to get depressed/pissed off Twitter still exists...
November 18, 2024 at 3:33 AM
I'm with Jony on this... I miss early Twitter when the feed was 100% cool science. It was such a cheat code! I hope bluesky can recreate that vibe. OFC if we want to get depressed/pissed off Twitter still exists...
Deleting will make it harder for people migrating here to find you. Also loss of valuable content. Why delete? Makes no sense.
November 17, 2024 at 3:37 PM
Deleting will make it harder for people migrating here to find you. Also loss of valuable content. Why delete? Makes no sense.