Morgan Jones
@04mjone.bsky.social
Structural biologist working to understand DNA replication at the MRC-LMB
Reposted by Morgan Jones
Glad to share our paper out today @NatureEcoEvo: “Serial innovations by Asgard archaea shaped the DNA replication machinery of the early eukaryotic ancestor”. www.nature.com/articles/s41... #microsky #archaeasky
Serial innovations by Asgard archaea shaped the DNA replication machinery of the early eukaryotic ancestor - Nature Ecology & Evolution
Phylogenetic and biochemical analyses show a diversity of components of the DNA replication machinery in different Asgard archaea that contributed to the eukaryotic DNA replication machinery.
www.nature.com
October 21, 2025 at 3:06 PM
Glad to share our paper out today @NatureEcoEvo: “Serial innovations by Asgard archaea shaped the DNA replication machinery of the early eukaryotic ancestor”. www.nature.com/articles/s41... #microsky #archaeasky
Reposted by Morgan Jones
We are recuiting two new Associate Professors here in Oxford Biochemistry. Come join us! Reach out to me if you have any questions. Please repost! tinyurl.com/mr3m7bd3
October 17, 2025 at 2:56 PM
We are recuiting two new Associate Professors here in Oxford Biochemistry. Come join us! Reach out to me if you have any questions. Please repost! tinyurl.com/mr3m7bd3
I’m really excited to share that I’ve been awarded a Wellcome Trust Career Development Award to start my own research group at Oxford University Biochemistry Department @BiochemOxford 🧬🎉
October 14, 2025 at 11:09 AM
I’m really excited to share that I’ve been awarded a Wellcome Trust Career Development Award to start my own research group at Oxford University Biochemistry Department @BiochemOxford 🧬🎉
Great new work from the very talented Emma Fletcher (@Yeeles_Lab). Biochemistry, and a touch of cryoEM, reveal why the DNA replication machinery needs a dedicated leading strand PCNA clamp loader. 🧬🧪🥼🔬🧑🔬
www.embopress.org/doi/full/10....
www.embopress.org/doi/full/10....
Competition for the nascent leading strand shapes the requirements for PCNA loading in the replisome | The EMBO Journal
imageimageCtf18-RFC is a dedicated leading-strand replication clamp loader, with RFC unable
to fulfil this role. This study provides a mechanistic basis as to why this is the
case and reveals unique f...
www.embopress.org
March 19, 2025 at 12:42 PM
Great new work from the very talented Emma Fletcher (@Yeeles_Lab). Biochemistry, and a touch of cryoEM, reveal why the DNA replication machinery needs a dedicated leading strand PCNA clamp loader. 🧬🧪🥼🔬🧑🔬
www.embopress.org/doi/full/10....
www.embopress.org/doi/full/10....