Zilu Ye
ziluye.bsky.social
Zilu Ye
@ziluye.bsky.social
Proteomics, Mass Spectrometry. Group leader at Institute of Systems Medicine, Chinese Academy of Medical Sciences.
Excited to share our latest work: End-to-end high-throughput single-cell proteomics via SPRINT and dual-spray LC-MS www.biorxiv.org/content/10.1...
End-to-end high-throughput single-cell proteomics via SPRINT and dual-spray LC-MS
Single-cell proteomics (SCP) enables direct measurement of protein heterogeneity but remains constrained by throughput and limited applicability to primary tissues. Here, we present an integrated work...
www.biorxiv.org
November 6, 2025 at 10:05 AM
Reposted by Zilu Ye
🚀 Excited to share our latest article in #singlecell proteomics published in Cell!
We've developed SC-pSILAC to simultaneously measure protein turnover and abundance in single cells, unlocking the first large-scale, 2D proteomic insights at single-cell resolution!

www.cell.com/cell/fulltex...
Global analysis of protein turnover dynamics in single cells
The SC-pSILAC method enables single-cell measurement of both protein abundance and turnover, providing notable advances in the depth and versatility of proteomic technologies.
eur02.safelinks.protection.outlook.com
March 31, 2025 at 3:12 PM