Wihuri Research Institute
@wrihelsinki.bsky.social
Wihuri Research Institute, a non-profit biomedical institute in Helsinki, drives fundamental research on vascular biology to advance human health. www.wri.fi
New study from Kati Öörni’s lab @katioorni.bsky.social at #WRIHelsinki on the effect of icosapent ethyl (IPE) on circulating lipoproteins and their pro-atherogenic properties.👇
Our latest study, published in @insight.jci.org , shows how high-dose icosapent ethyl (IPE), an ethyl ester of eicosapentaenoic acid (EPA) remodels circulating lipoproteins and reduces cardiovascular risk markers in healthy individuals.
insight.jci.org/articles/vie...
insight.jci.org/articles/vie...
October 21, 2025 at 7:30 AM
New study from Kati Öörni’s lab @katioorni.bsky.social at #WRIHelsinki on the effect of icosapent ethyl (IPE) on circulating lipoproteins and their pro-atherogenic properties.👇
New study from Taija Mäkinen's lab @taijamakinenlab.bsky.social at the #WRIHelsinki featured on the cover of @natcardiovascres.nature.com: A ‘feedforward’ circuit amplifying upstream TIE2 receptor signalling drives PIK3CA-driven venous malformation - and can be therapeutically targeted in mice.👇
❤️Our July issue is out❤️Discover an Angiopoietin-TIE2-dependent circuit promoting venous malformations, complex disease modelling in cardiac organoids, regulation of cardiac homeostasis by methyonil tRNA synthetase, and more!
www.nature.com/natcardiovas...
www.nature.com/natcardiovas...
July 17, 2025 at 11:51 AM
New study from Taija Mäkinen's lab @taijamakinenlab.bsky.social at the #WRIHelsinki featured on the cover of @natcardiovascres.nature.com: A ‘feedforward’ circuit amplifying upstream TIE2 receptor signalling drives PIK3CA-driven venous malformation - and can be therapeutically targeted in mice.👇
New study from Riikka Kivelä's lab @riikka-k.bsky.social at the #WRIHelsinki: Combined gene therapy with Pro-MSTN and VEGF-B boosts muscle growth and improves body composition.👇
journals.physiology.org/doi/abs/10.1...
journals.physiology.org/doi/abs/10.1...
Combined angiogenic and hypertrophic gene therapy enhances skeletal muscle growth | American Journal of Physiology-Cell Physiology | American Physiological Society
Skeletal muscle atrophy in response to pathophysiological stimuli or disuse includes loss of muscle mass and strength. Targeting signaling pathways regulating muscle growth can counteract muscle loss,...
journals.physiology.org
July 16, 2025 at 10:16 AM
New study from Riikka Kivelä's lab @riikka-k.bsky.social at the #WRIHelsinki: Combined gene therapy with Pro-MSTN and VEGF-B boosts muscle growth and improves body composition.👇
journals.physiology.org/doi/abs/10.1...
journals.physiology.org/doi/abs/10.1...
Taija Mäkinen @taijamakinenlab.bsky.social from the Wihuri Research Institute and University of Helsinki @helsinki.fi has been elected as a new #EMBO member
Welcome and congratulations to the 60 new members and 9 associate members who have been elected to the EMBO Membership! This honour celebrates #research excellence and outstanding achievements in the #LifeSciences. 🧪
Learn more here:
www.embo.org/press-releas... #EMBOMembers2025
Learn more here:
www.embo.org/press-releas... #EMBOMembers2025
Outstanding life scientists elected to the EMBO Membership – Press releases – EMBO
Sixty-nine new members join the community of leading life scientists in Europe and beyond
www.embo.org
July 4, 2025 at 8:40 AM
Taija Mäkinen @taijamakinenlab.bsky.social from the Wihuri Research Institute and University of Helsinki @helsinki.fi has been elected as a new #EMBO member
New study from Riikka Kivelä’s lab @riikka-k.bsky.social ky.social at the #WRIHelsinki: Mechanical loading triggers cell type-specific responses in endothelial and muscle cells.👇
www.biorxiv.org/content/10.1...
Check how differently muscle cells and endothelial cells respond to mechanical loading from our latest study. Great work by @erikniemi.bsky.social @smantyselka.bsky.social and collaboration with @juhahulmi.bsky.social. Supported by @wrihelsinki.bsky.social
Check how differently muscle cells and endothelial cells respond to mechanical loading from our latest study. Great work by @erikniemi.bsky.social @smantyselka.bsky.social and collaboration with @juhahulmi.bsky.social. Supported by @wrihelsinki.bsky.social
Mechanical loading reveals cell type-specific responses and role of PHGDH in endothelial cell growth
Skeletal muscle and blood vessels are constantly subjected to mechanical forces, especially during exercise. We subjected human endothelial cells (ECs) and muscle cells (MCs) to cyclic mechanical stre...
www.biorxiv.org
July 4, 2025 at 8:22 AM
New study from Riikka Kivelä’s lab @riikka-k.bsky.social ky.social at the #WRIHelsinki: Mechanical loading triggers cell type-specific responses in endothelial and muscle cells.👇
Thank you to everyone who joined the #WRISymposium for a day of exciting #VascularBiology research and great discussions—see you next year!
June 11, 2025 at 4:02 AM
Thank you to everyone who joined the #WRISymposium for a day of exciting #VascularBiology research and great discussions—see you next year!
We are the Wihuri Research Institute, a non-profit biomedical organization based in Helsinki, Finland. Our mission is to advance fundamental research in vascular biology to better understand human health and disease.
Learn more about our work: wri.fi
#WihuriResearch #VascularBiology
Learn more about our work: wri.fi
#WihuriResearch #VascularBiology
June 8, 2025 at 12:44 PM
We are the Wihuri Research Institute, a non-profit biomedical organization based in Helsinki, Finland. Our mission is to advance fundamental research in vascular biology to better understand human health and disease.
Learn more about our work: wri.fi
#WihuriResearch #VascularBiology
Learn more about our work: wri.fi
#WihuriResearch #VascularBiology