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washuonr.bsky.social
@washuonr.bsky.social
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Developing new machine learning and AI algorithms in AD, Ganesh B.Chand at @washumedicine.bsky.social MIR aims to be the first to systematically investigate the intricate relationships among biomarkers, neuropsychiatric symptoms, vascular risks and genetic predisposition.

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$3.2 Million Grant Supports Study of Neuropsychiatric Symptoms in Alzheimer’s Disease - Mallinckrodt Institute of Radiology - WashU Medicine
Ganesh Chand, PhD, received a four-year, $3.2 million NIH grant to study the neuropsychiatric mechanisms in AD.
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November 13, 2025 at 8:15 PM
The lab of Alexandra Rutz including Anna Goestenkors @washuengineers.bsky.social created granular hydrogels made of microparticles. With Barani Raman, hydrogels on tips of locust antennae enabled measurement of field measurements during locusts' odor sensation.
Extrudable hydrogels act as bioelectronic conductors
Research in Alexandra Rutz’s lab creates hydrogels that could measure biological activity
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November 6, 2025 at 4:57 PM
The BRAVE project @arpa-h.bsky.social aims to develop bioaerosol sensors to disrupt infectious disease transmission. WashU team includes Rajan Chakrabarty @washuengineers.bsky.social, John Cirrito @washuneurology.bsky.social, Carla Yuede in Psychiatry @washumedicine.bsky.social

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Disrupting infectious diseases
With a grant from the Advanced Research Projects Agency for Health, a multi-institutional research team led by scientists at Virginia Tech and Washington University in St. Louis will develop an indoor...
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October 28, 2025 at 5:44 PM
With funds from NIH, @alsassociation.bsky.social , and Target ALS Foundation, Macy Sprunger and Meredith Jackrel @washu.edu and collaborators purified and visualized Matrin-3, a major advance for studying the root causes of ALS. Findings published @cp-molcell.bsky.social .

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WashU chemists reveal new insights into ALS-linked protein
Using advanced biophysical and imaging techniques, Meredith Jackrel and her team have isolated Matrin-3 to better understand its role in neurodegenerative diseases.
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October 24, 2025 at 3:04 PM
With an NIH grant, ShiNung Ching from the McKelvey School of Engineering and Ben Palanca @washumedicine.bsky.social seek personalized medicine strategies for treatment-resistant depression by developing a data-driven modeling method to identify how the brain responds to propofol.

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Personalized brain modeling of anesthetic effects to predict antidepressant response
ShiNung Ching, Ben Julian Palanca, MD, PhD, look at brain dynamics, neural circuits as clues to alternative approaches
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October 22, 2025 at 5:42 PM
New study by Joe Feldman @washuartsci.bsky.social and collaborators links lead exposure to lower standardized test scores. Using models to fill in missing lead exposure data, they predict an even stronger impact of lead on test score performance.

#WashUNeuroCommunity

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New study may help uncover childhood lead exposure's true impact
Data scientists at Washington University in St. Louis used new statistical tools to find that the association between lead exposure and academic test scores may be even stronger than previously suspec...
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October 3, 2025 at 6:22 PM
A team including Jose Moron-Concepcion, Erik Musiek and Khairunisa Ibrahim @washumedicine.bsky.social and others generated a model to explore links between chronic pain and sleep disruption. Findings published in @npp-journal.bsky.social.

#WashUNeuroCommunity
Mouse study links chronic pain to disrupted sleep patterns
Researchers at Washington University in St. Louis School of Medicine have developed the first mouse model to replicate the disrupted sleep patterns seen in people with chronic pain.
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September 25, 2025 at 2:36 PM
What do our words reveal about us? Josh Oltmanns of Psychological and Brain Sciences @washu.edu (Arts & Sciences) and colleagues are developing AI tools to help psychologists uncover hidden cues in language that reflect personality traits and mental-health signals.

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What do our words say about our minds?
Words are windows into the brain. The words that we choose — and how we say them — speak volumes about our personalities and even our mental health, said Josh Oltmanns, an assistant professor of psych...
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September 17, 2025 at 1:30 PM
A team led by @drbhooma.bsky.social
@washuneurology.bsky.social @washumedicine.bsky.social identified an objective measure of leg dystonia in children with cerebral palsy, and mimicked this measurement in mice to better understand causes and possible therapies for dystonia.

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New method accurately assesses movement disorder in children | WashU Medicine
A study in humans and mice from WashU Medicine could inform new treatments for leg dystonia, a common complication of cerebral palsy.
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September 9, 2025 at 5:08 PM
Charles Conway (Psychiatry @washumedicine.bsky.social) reports a new study in which participants with treatment-resistant depression received vagus nerve stimulation for one year via a pacemaker-like device implanted under the skin. Patients reported improved lives.

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Hope for those with treatment-resistant depression
A WashU Medicine study paves the way to make an effective treatment more accessible to those 'paralyzed by life.'
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August 29, 2025 at 7:26 PM
Christina Gurnett and Lawrence Salkoff report in
Frontiers of Pharmacology that fluoxetine (Prozac) improved seizure control in two sisters, patients of Dr. Gurnett with a rare pathogenic variant in the KCNC2 gene, identified by @tycheleturner.bsky.social‬.

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WashU Medicine researchers identify potential for repurposing Prozac to treat rare epilepsy - Department of Neuroscience
Gurnett and Salkoff are lead authors on a case report on how Prozac can be used in the treatment of children with rare forms of epilepsy.
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August 25, 2025 at 2:13 PM
Hong Chen @washuengineers.bsky.social in the Department of Neurosurgery aims to develop synthetic torpor (lower temp, metabolism) using focused ultrasound, with potential for stroke neuroprotection, organ preservation, lifespan extension and others.
#WashUNeuroCommunity
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WashU Expert: Synthetic torpor has potential to redefine medicine
Hong Chen, a biomedical engineer at Washington University in St. Louis, shares the potential for using synthetic torpor technology to develop new treatments for a range of illnesses and injuries.
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August 7, 2025 at 2:18 PM
A new study by Carlos Cruchage and Muhammad Ali WashU Psychiatry @washumedicine.bsky.social published in @naturemedicine.bsky.social used plasma from 10,500+ patients with Alzheimer's disease, Parkinson's or FTD to create and validate a model to predict risk of each disease.

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Blood plasma reveals shared pathways in neurodegenerative diseases
Washington University in St. Louis School of Medicine researchers identify biomarkers of Alzheimer’s, Parkinson’s and frontotemporal dementia from blood plasma, suggesting new therapeutic avenues.
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July 31, 2025 at 4:18 PM
The @WashUNeurology @washuneurology.bsky.social has been selected by The Michael J. Fox Foundation as one of eight new sites for the Edmond J. Safra Fellowship in Movement Disorders. The new program will be led by Baijayanta Maiti, MD, PhD.

#WashUNeuroCommunity

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WashU Medicine selected for Parkinson’s disease training program | WashU Medicine
Edmond J. Safra Fellowship to fund training of movement disorder specialist in the Department of Neurology
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July 16, 2025 at 8:21 PM
A new paper by Theresa Gildner of @washuartsci.bsky.social and Annette Langer-Gould of Los Angeles General Medical Center finds that #MS is more common in Black than white women, and that disparities in the environment and the health system are driving that trend.

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Unequal risk: Why MS is a growing problem in Black communities
A new paper is challenging longstanding misconceptions about multiple sclerosis, a common autoimmune disease that affects roughly one million people in the United States. “For many years, MS was seen ...
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July 15, 2025 at 6:53 PM
Andrew Yoo and Zhao Sun of @washumedicine.bsky.social receive Morby Prize @curealzheimersfund.bsky.social ‪for seminal study in @science.org to show skin cells from patients with late-onset Alzheimer’s can be transformed into neurons and reproduce hallmarks of the disease bit.ly/4kxcmf6
Yoo, Sun recognized for developing novel method to study aged neurons | WashU Medicine
Morby prize from Cure Alzheimer’s Fund honors groundbreaking Alzheimer’s research
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July 11, 2025 at 5:59 PM
The Saint Louis Science Center / WashU St. Louis Neuroscience Outreach invite you to Up Late: Experience Sound on July 19 where @washu.edu ‬grad students will be among the presenters testing the limits of human hearing. #WashUNeuroCommunity

For tickets and more information, visit slsc.org/up-late
July 10, 2025 at 6:17 PM
A collaboration among Ben Warner and Chenyang Lu at the McKelvey School of Engineering along with Sarah England and Peinan Zhao at WashU OBGYN shows sleep patterns in people experiencing pregnancy can effectively predict preterm birth.

@washu.bsky.social
#WashUNeuroCommunity

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Sleep data from wearable device may help predict preterm birth
An interdisciplinary research team at Washington University in St. Louis has found that variability in sleep patterns in people experiencing pregnancy can effectively predict preterm birth.
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July 2, 2025 at 6:32 PM
Keith Hengen @washuartsci.bsky.social notes that “criticality” - the tipping point between order & chaos - is the key to understanding how the brain works, & how to keep it free from Alzheimer’s and other diseases.

Woodrow Shew @uarkansas.bsky.social

#WashUNeuroCommunity

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A unified theory of the mind
In a new paper with implications for preventing Alzheimer’s disease and other neurological disorders, Keith Hengen, an associate professor of biology, suggests a new comprehensive approach to understa...
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June 27, 2025 at 3:27 PM
@iddrc-washu.bsky.social + The McDonnell Genome Institute @washumedicine.bsky.social secure a $12M NIH grant to form the Scalable Mouse Assay Center. Led by Joseph Dougherty - WU-SMAC will curate models of neurodevelopmental/psychiatric disorders known to be caused by a single gene mutation.
$12 million grant funds studies of role of genes in autism, similar diagnoses
Researchers at Washington University School of Medicine in St. Louis received a $12 million National Institutes of Health (NIH) grant to deepen understanding of autism and other neurodevelopmental and psychiatric disorders that are caused by a single gene mutation.
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June 23, 2025 at 7:11 PM
Rohit Pappu ‪‪@washuengineers.bsky.social - Center for Biomolecular Condensates with @stjuderesearch.bsky.social found 1) distinct mechanisms for biomolecular condensate vs fibril formation; 2) condensates are metastable sinks that detour proteins from pathological fibrillar solids.
Research untangles role of stress granules in neurodegenerative disease
Researchers at Washington University in St. Louis and St. Jude Children’s Research Hospital have found that biomolecular condensates play a role in suppressing the effects of ALS-causing mutations.
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June 19, 2025 at 8:01 PM
Join the St. Louis Translational Pain Research Forum September 26-27, 2025, hosted by the Institute of Translational Neuroscience @slu-official.bsky.social and Center for Clinical Pharmacology @washumedicine.bsky.social

Register Here: bit.ly/4n3Uo6F
June 17, 2025 at 4:39 PM
Different kinds of mindfulness practices might be helpful for different varieties of anxiety, helping to illuminate how to match anxiety sufferers with more precise treatments.

Resh Gupta and Todd Braver of @washuartsci.bsky.social

#WashUNeuroCommunity
Can mindfulness combat anxiety?
Resh Gupta If you’re anxious about work, finances, the state of the world, or anything else, you might try a moment of mindfulness. Paying close attention to the present moment without judgment — the ...
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June 12, 2025 at 6:01 PM
Astrocytes Take the Lead in Neural Rewiring - this discovery fundamentally changes current understanding about the determinants of brain network communication and activity.

Dr. Thomas Papouin
@washumedicine.bsky.social

#WashUNeuroCommunity

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Overlooked cell type orchestrates brain rewiring | WashU Medicine
Rather than neurons, brain cells known as astrocytes take charge in shaping response to signal involved in vigilance, mouse study shows
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June 9, 2025 at 7:00 PM
It's not too late - comment on proposed Schedule F!

Under Schedule F, NIH Institute Directors could become political appointees. This is your opportunity to share your opinion: How would politicization impact the federal grant process?

Deadline June 7!

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Improving Performance, Accountability and Responsiveness in the Civil Service
The Office of Personnel Management (OPM) is proposing a rule to increase career employee accountability. Agency supervisors report great difficulty removing employees for poor performance or misconduc...
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June 4, 2025 at 6:49 PM