Taryn Beckman
tbeckman.bsky.social
Taryn Beckman
@tbeckman.bsky.social
PhD Candidate, immunoengineering and metabolism, Hubbell lab @ Uchicago
I am excited to share my publication in collaboration with @lisarvolpatti.bsky.social! We found that a novel engineered prodrug allows systemic circulation of Butyrate, slowing atherosclerosis disease progression through immune and metabolic mechanisms.

insight.jci.org/articles/vie...
insight.jci.org
August 28, 2025 at 2:50 PM
Reposted by Taryn Beckman
An atlas of metabolites driving chemotaxis in prokaryotes

This database compiles the effects (attractant, repellent or neutral) of 926 compounds and the chemotactic behaviour of 394 strains

#ChemicalBiology #Microbiology
An atlas of metabolites driving chemotaxis in prokaryotes - Nature Communications
In this meta-analysis, the authors compile results from 60 years of chemotaxis research into a database of prokaryotic chemoeffectors that compares and analyses their effects as attractant, repellent or neutral compounds, as well as the chemotactic behaviour of responding microorganisms.
bit.ly
May 8, 2025 at 12:51 PM
Reposted by Taryn Beckman
Nature research paper: Activation of lysosomal iron triggers ferroptosis in cancer

https://go.nature.com/4jO9ZVX
Activation of lysosomal iron triggers ferroptosis in cancer - Nature
Some cancer cells exhibit high loads of reactive iron in lysosomes, and this feature is exploited by using fentomycin-1, a newly developed small molecule, to induce ferroptosis.
go.nature.com
May 8, 2025 at 10:24 AM
Reposted by Taryn Beckman
Multiomics reveal key inflammatory drivers of severe obesity: IL4R, LILRA5, and OSM
www.cell.com/cell-genomic...
March 4, 2025 at 4:58 PM
Reposted by Taryn Beckman
Tomatoes lose their bitterness and toxicity as they ripen thanks to DNA demethylation, the hormone ethylene, and key transcription factors, finds a new #ScienceAdvances study. scim.ag/4bfdr8u
Removal of toxic steroidal glycoalkaloids and bitterness in tomato is controlled by a complex epigenetic and genetic network
A complex regulatory network controls the removal of toxic steroidal glycoalkaloids during tomato ripening.
scim.ag
February 25, 2025 at 2:25 PM
Reposted by Taryn Beckman
Reposted by Taryn Beckman
Trump’s siege of science: how the first 30 days unfolded & what’s next

Once upon a time leaders believed that science was essential to nation’s security, to better health, to more jobs, to a higher standard of living & to cultural progress
🧪 #academicSky
@nature.com
www.nature.com/articles/d41...
Trump’s siege of science: how the first 30 days unfolded and what’s next
The breakneck pace and devastating impact of the administration’s policy changes has shocked researchers.
www.nature.com
February 20, 2025 at 7:59 PM
Reposted by Taryn Beckman
🧪Thrilled to share the latest research from the lab of my awesome @umasschan.bsky.social colleague Jessica Spinelli (who isn't on here yet) and collaborators:
www.cell.com/cell/fulltex...
Rhodoquinone carries electrons in the mammalian electron transport chain
Valeros et al. identify rhodoquinone (RQ), an electron carrier present in mammalian mitochondria, that can deliver electrons to fumarate instead of O2 as the terminal electron acceptor. The authors de...
www.cell.com
February 4, 2025 at 4:24 PM