Tata Kavlashvili
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tatakavlashvili.bsky.social
Tata Kavlashvili
@tatakavlashvili.bsky.social
@DamonRunyon.org Timmerman Traverse Fellow www.sfeirlab.com MSK • PhD in Dewar lab @vanderbilt.edu • from Tbilisi, Georgia 🇬🇪 basic scientist fascinated by mtDNA+🏔️⛷️🎭🗽NYC📍
Day 5 - Trek to Dengboche with incredible views of Mt. Everest with the Timmerman Traverse for @damonrunyon.org team!
April 20, 2025 at 2:35 AM
Timmerman Traverse for @damonrunyon.org. Trekking to Everest Base Camp with our first sight of the top of the world today in Syangboche! Absolutely epic!
April 17, 2025 at 4:53 AM
Excited to share my first postdoc paper - a tool to engineer mtDNA deletions in human cells and study their pathogenic impact ✂️🧬🧫
Combining bacterial end joining with programmable nucleases, we induced mtDNA deletions in human cells at varying heteroplasmy and examined their metabolic and cellular effects. Simple tool to apply across any cell type and engineer pathogenic mtDNA deletions. www.sciencedirect.com/science/arti...
Engineering mtDNA deletions by reconstituting end joining in human mitochondria
Recent breakthroughs in the genetic manipulation of mitochondrial DNA (mtDNA) have enabled precise base substitutions and the efficient elimination of…
www.sciencedirect.com
March 11, 2025 at 9:40 PM