Tom Longden
@talongden.bsky.social
Neurovascular physiologist | Assistant Professor at the University of Maryland Baltimore | Avid sci-fi nerd
Reposted by Tom Longden
New publication Alert: Delighted to share our latest work. We describe a unique relationship between electrical and Calcium signaling; 'Electro-Calcium Coupling' in brain capillary endothelial cells.
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
December 11, 2024 at 11:35 PM
New publication Alert: Delighted to share our latest work. We describe a unique relationship between electrical and Calcium signaling; 'Electro-Calcium Coupling' in brain capillary endothelial cells.
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Congrats guys! Looking sharp also
Last week we had the honour and surprise of winning the BHF Research Story of the Year award. The award was based off our work published last year, and was only possible due to an amazing group of scientist at the University of Manchester and the Geoffrey Jefferson Brain Research Centre.
December 10, 2024 at 1:04 PM
Congrats guys! Looking sharp also
I am delighted to share the work of my amazing student Dominic Isaacs! Out today in PNAS (www.pnas.org/doi/10.1073/...), Dom beautifully used optogenetics to show that thin-strand pericytes in the brain can send long-range electrical signals to control arteriole diameter and brain blood flow.
December 4, 2024 at 7:05 PM
I am delighted to share the work of my amazing student Dominic Isaacs! Out today in PNAS (www.pnas.org/doi/10.1073/...), Dom beautifully used optogenetics to show that thin-strand pericytes in the brain can send long-range electrical signals to control arteriole diameter and brain blood flow.
Reposted by Tom Longden
Our paper is out just in time for #EM_Monday! It is about a specialized neuron-specific ER, called the spine apparatus, which is found close to synapses and has a very peculiar shape. If you think neurons are special, the spine apparatus is their🦄 horn! But how does it form?!
doi.org/10.1016/j.cu...
doi.org/10.1016/j.cu...
December 2, 2024 at 5:52 PM
Our paper is out just in time for #EM_Monday! It is about a specialized neuron-specific ER, called the spine apparatus, which is found close to synapses and has a very peculiar shape. If you think neurons are special, the spine apparatus is their🦄 horn! But how does it form?!
doi.org/10.1016/j.cu...
doi.org/10.1016/j.cu...
Reposted by Tom Longden
Oh my. This is just gorgeous from Misha Kudryashev's lab (I don't think he's here yet?). Love to see it. V ATPase resolved directly in synaptic vesicles 🤤 Lots of other neat observations in there also. Congrats to all involved! www.pnas.org/doi/10.1073/...
December 2, 2024 at 4:30 AM
Oh my. This is just gorgeous from Misha Kudryashev's lab (I don't think he's here yet?). Love to see it. V ATPase resolved directly in synaptic vesicles 🤤 Lots of other neat observations in there also. Congrats to all involved! www.pnas.org/doi/10.1073/...
Reposted by Tom Longden
