PhD position alert 📢📢📢

🦠 Impact of microbiome biotransformation on chemical toxicity
🏢 ETH Zürich, Laboratory of toxicology
🧑‍🔬 @georgaichinger.bsky.social & @profshana.bsky.social

jobs.ethz.ch/job/view/JOP...

#NAMs #microbiome #bioinformatics #PhDPosition #toxicity #science #career #AcademicJobs

New publication alert! Click-code-seq, our DNA-damage sequencing method, is now out! This tool can advance our understanding of aging, cancer and neurodegeneration. Huge thanks to the amazing collaborative team behind this! @sturlalab.bsky.social @ethz.ch

@georgaichinger.bsky.social & @profshana.bsky.social presented at #ICT2025 in Beijing! 🌏

KL “Advancing Chemical Research in Toxicology: From Genotoxicity to Gut Microbial Metabolism”
“Quantifying the Gut Microbiome’s Impact on Toxicokinetics by PBK Modeling.”

#IUTOX2025 @nynkekramer.bsky.social

Exciting contribution from our lab at the 8th EU–US Conference on Endogenous DNA Damage and Repair! 🔬🌍

Dr. Vakil Takhaveev (@vakil-takhaveev.bsky.social) presented a great showcase of how innovative sequencing approaches advance our understanding of genome integrity. 💡🧬

Great reception to our work in India! 🙌🏽
Shana Sturla presented our research “Mapping chemical modifications throughout the human genome” at the Global Scientific Conference 2025, VMCC IIT Bombay, bringing global experts together to turn discovery into impact. 🌍🔬

If you need information on carcinogenic alkylating agents, check out this amazing new book chapter! 📘✨

Authors: Jasmin Huber, Monika Kojic, Claudia Aloisi, and Shana Sturla 👉 doi.org/10.1016/B978...

Congrats to all authors for this outstanding contribution to the field of molecular toxicology! 👏🧬

🎓 Big congrats to our MSc student Emanuel Schönbächler for successfully defending his thesis: “Expanding Click-Code-Sequencing for Mapping Oxidative and Alkylation DNA Modifications.” 💥🧬

It's finally published in ES&T:
We developed a PBK model for BPA analogues with a multimodal parameterization approach.
👉 yes we can! (predict biokinetics without in vivo data)
👉 analogues reach much higher internal concentrations than BPA

#toxicology #plastics #EDCs

pubs.acs.org/doi/10.1021/...

PhD student Emilie Aghajani and Dr. @vakil-takhaveev.bsky.social represented us at #ARDD2025 in Copenhagen, sharing their work on developing mechanistic biomarkers of aging through genome-wide DNA damage mapping. A fantastic opportunity to connect with the aging research community!

Our fantastic postdoc Vakil Takhaveev (@vakil-takhaveev.bsky.social) rocked the EFMC Young Medicinal Chemists’ Symposium in Porto 🇵🇹 @euromedchem.bsky.social, presenting how DNA-damage sequencing can reveal anti-cancer drug mechanisms and push precision oncology forward! ✨🧬

🌍 Our team had the privilege to showcase our latest advances in developing #NAMs under the equator at #WC13! ✨

🔬 @georgaichinger.bsky.social – microbiome-competent biokinetic modeling
🧪 Blandine Descamps – prediction of emerging mycotoxins toxicokinetics
⚖️ Hélène Bigonne – sex-informed PBK models

✨ Our lab members Nina Frei, Jasmin Huber, and Lucie Lefevre had an inspiring day at the SCS Fall Meeting 2025 @swisschemistry.bsky.social in Zürich! It was a fantastic opportunity to exchange ideas, discover cutting-edge research, and connect with the vibrant Swiss chemistry community. 🌍🔬💡

Great discussions at the #Metabolomics2025 in Prague ! ✨
Our brilliant postdoc Jacob Folz presented his research on "Quantifying rate and global profile of gut microbiota metabolism ex vivo by LC-MS/MS". 🦠
Stay tuned - his new publication is on the way ! 😉

Quite a day at the Annual Meeting of the Swiss Society of Toxicology with talks by @georgaichinger.bsky.social (microbiome-competent PK modeling) & @vakil-takhaveev.bsky.social (DNA damage sequencing).
Special Congrats to PhDs Alona Slastennikova and Blandine Descamps who received poster awards!💪🥳