Sinead O'Sullivan
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sineadosullivan.bsky.social
Sinead O'Sullivan
@sineadosullivan.bsky.social
🧠 Neuroscientist | Postdoc Fellow @DZNE
🔬 mitochondria | myelination | protein aggregation | neurodegeneration 🪐 Amateur astronomer & stargazer | Exploring the universe, one neuron & star at a time
Reposted by Sinead O'Sullivan
If you’re in San Diego for #Sfn25, come by on Wednesday at 2 pm for a session on oligodendrocyte pathophysiology and repair mechanisms in multiple sclerosis, Alzheimer’s, and Parkinson’s disease. Would be great to see some familiar (and new) faces there!
November 17, 2025 at 9:22 PM
Reposted by Sinead O'Sullivan
I am thrilled to share our latest article that has been published in @cp-immunity.bsky.social. We describe a new role for NLRP3 outside of its #inflammasome complex, where it can regulate microglial #metabolism & key metabolites that affect the epigenetic landscape(1)
www.cell.com/immunity/ful...
NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer’s disease progression
How NLRP3 impacts Alzheimer’s disease (AD) is unclear. McManus et al. find that NLRP3 is located at mitochondria where it regulates microglial metabolism. Depletion or chronic pharmacological inhibiti...
www.cell.com
February 3, 2025 at 4:18 PM
Reposted by Sinead O'Sullivan
We're excited for the Darwin Day Lecture on 7 February with
@jimalkhalili.bsky.social. Book your tickets and join us as we track the brain's 700 million-year evolutionary history, and explore how it developed from simple nerve cells to a remarkably complex human system. humanists.uk/events/darwi...
The story of the human brain, with Jim Al-Khalili | The Darwin Day Lecture 2025
humanists.uk
January 29, 2025 at 11:52 AM
🚨We are hiring! Postdoc position available at the DZNE Bonn, to study the role of oligodendrocytes in the progression of Parkinson's disease!🧠🔬
jobs.dzne.de/de/jobs/1014...
Postdoc (f/m/x) 1383/2025/1
jobs.dzne.de
January 13, 2025 at 9:25 AM