Serena Nik-Zainal
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serenanikzainal.bsky.social
Serena Nik-Zainal
@serenanikzainal.bsky.social
Signposting the upcoming Early Detection of Cancer Conference, October 21-23, 2025, Portland, Oregon.
www.earlydetectionresearch.com
Make sure you get your tickets now! ☺️
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The Early Detection of Cancer Conference brings together experts in early detection from multiple disciplines to share ground breaking research and progress in the field.
www.earlydetectionresearch.com
July 13, 2025 at 2:54 PM
PAPER OUT!! 🥳🎉💃🏻🕺🏻💃🏻🕺🏻

A redefined InDel taxonomy provides insights into mutational signatures @NatureGenet

Brainchild of the amazing #GeneKoh
(Sir Jeffrey Cheah ECR)

Tweetorial below!! 👇

1/n

www.nature.com/articles/s41...
A redefined InDel taxonomy provides insights into mutational signatures - Nature Genetics
This paper describes a framework for classifying small insertions and deletions from genomic data and applies it to a large dataset comprising seven tumor types. The analysis highlights new insertion ...
www.nature.com
April 10, 2025 at 4:48 PM
Reposted by Serena Nik-Zainal
Credit to supervisors @derm-scientist.bsky.social and @serenanikzainal.bsky.social and co-authors Dr. Koh, Ms. Holt, Dr. Husain, Dr. Namini, Dr. Mathew, Dr. Memari, and Dr. Davies for their hard work on this project 👏🏼

academic.oup.com/ced/advance-...
Metastatic malignant cylindroma arising on a background of digenic inheritance of BRCA2 and CYLD pathogenic variants targeted with PARP inhibition
Management of malignant cylindroma, particularly in the case of metastasis, poses a difficult challenge for clinicians and is limited by a lack of randomiz
academic.oup.com
March 24, 2025 at 10:40 AM
Reposted by Serena Nik-Zainal
There's a month left for you to submit an abstract or apply for a Travel Grant to attend the next edition of Defence is the Best Attack, taking place in Barcelona in May! ☀️

Join us for an overview of the most recent advances in the field of immunotherapy:

eacr.org/conference/d...
February 17, 2025 at 10:22 AM
Half-term hols in UK.

Our house is FULL of 17 year old girls dancing and singing
#Galentines
ahead of Valentines…💖
February 10, 2025 at 9:04 PM
Reposted by Serena Nik-Zainal
Dear all,

Postdoc positions are available to work on (1) the role of DNA strand break repair proteins during DNA replication and (2) the molecular/structural biology of XRCC1 protein complexes, as part of our work on genetic diseases & cancer. Contact me if interested: k.w.caldecott@sussex.ac.uk
February 10, 2025 at 2:45 PM