Daniel Sauter
@sauterlab.bsky.social
Virologist & Research Group Leader at @unituebingen.bsky.social
Fascinated by viruses, innate immunity, evolution — and birds 🐦
#Virology #HIV #HERVs #Retrotransposons #Birds
Fascinated by viruses, innate immunity, evolution — and birds 🐦
#Virology #HIV #HERVs #Retrotransposons #Birds
Reposted by Daniel Sauter
We are looking to recruit a Ph.D. student to start in Q1 2026 for an exciting new project that is part of the newly funded SynthImmune Cluster of Excellence. Are you interested in the intersection of virology and immunology? Please see the attached info and apply at application.synthimmune.de.
November 10, 2025 at 3:44 PM
We are looking to recruit a Ph.D. student to start in Q1 2026 for an exciting new project that is part of the newly funded SynthImmune Cluster of Excellence. Are you interested in the intersection of virology and immunology? Please see the attached info and apply at application.synthimmune.de.
Reposted by Daniel Sauter
We’ve identified a highly divergent betacoronavirus from South American bat that encodes a functional furin cleavage site.
Another fascinating reminder of how diverse coronavirus evolution is in wildlife reservoirs.
#Virology #VirusEvolution #Bats #Coronavirus
www.biorxiv.org/content/10.1...
Another fascinating reminder of how diverse coronavirus evolution is in wildlife reservoirs.
#Virology #VirusEvolution #Bats #Coronavirus
www.biorxiv.org/content/10.1...
A divergent betacoronavirus with a functional furin cleavage site in South American bats
Bats are natural reservoirs for a wide range of RNA viruses. Members of the genus Betacoronavirus, including Severe Acute Respiratory Syndrome virus 2 (SARS-CoV-2) and Middle East Respiratory Syndrome...
www.biorxiv.org
October 27, 2025 at 9:32 PM
We’ve identified a highly divergent betacoronavirus from South American bat that encodes a functional furin cleavage site.
Another fascinating reminder of how diverse coronavirus evolution is in wildlife reservoirs.
#Virology #VirusEvolution #Bats #Coronavirus
www.biorxiv.org/content/10.1...
Another fascinating reminder of how diverse coronavirus evolution is in wildlife reservoirs.
#Virology #VirusEvolution #Bats #Coronavirus
www.biorxiv.org/content/10.1...
Reposted by Daniel Sauter
October 31, 2025 at 3:23 PM
Did you know? Fairywrens (Malurus cyaneus) and many other bird species share a common alarm call to alert neighbors of approaching cuckoos. Could this be how shared language evolves? pubmed.ncbi.nlm.nih.gov/41044184/ 📸 Caroline Jones, via Wikimedia Commons (CC0)
#Birds #FeatheredFriday
#Birds #FeatheredFriday
October 31, 2025 at 4:49 PM
Did you know? Fairywrens (Malurus cyaneus) and many other bird species share a common alarm call to alert neighbors of approaching cuckoos. Could this be how shared language evolves? pubmed.ncbi.nlm.nih.gov/41044184/ 📸 Caroline Jones, via Wikimedia Commons (CC0)
#Birds #FeatheredFriday
#Birds #FeatheredFriday
Reposted by Daniel Sauter
Only few days left! ⏰
Apply for the new
@gesvirologie.bsky.social
Pulication Prizes for Innovative Methods in Virology 🏆
- Biosafety, Biosecurity and Risk Mitigation 🦠
- Application of the 3R principle (Replace, Reduce, Refine) 🐭
Deadline: November 1st
g-f-v.org/en/forschung...
Apply for the new
@gesvirologie.bsky.social
Pulication Prizes for Innovative Methods in Virology 🏆
- Biosafety, Biosecurity and Risk Mitigation 🦠
- Application of the 3R principle (Replace, Reduce, Refine) 🐭
Deadline: November 1st
g-f-v.org/en/forschung...
Research Awards | Society of Virology
g-f-v.org
October 29, 2025 at 11:40 AM
Only few days left! ⏰
Apply for the new
@gesvirologie.bsky.social
Pulication Prizes for Innovative Methods in Virology 🏆
- Biosafety, Biosecurity and Risk Mitigation 🦠
- Application of the 3R principle (Replace, Reduce, Refine) 🐭
Deadline: November 1st
g-f-v.org/en/forschung...
Apply for the new
@gesvirologie.bsky.social
Pulication Prizes for Innovative Methods in Virology 🏆
- Biosafety, Biosecurity and Risk Mitigation 🦠
- Application of the 3R principle (Replace, Reduce, Refine) 🐭
Deadline: November 1st
g-f-v.org/en/forschung...
New paper out!
We show that APOBEC3B, a key repressor of retrotransposons, is downregulated in senescent cells — unleashing LINE-1 activity and fueling genomic instability and aging.
🔗 doi.org/10.1186/s13100-025-00378-5
#Retrotransposons #APOBEC3B #Senescence #Aging
We show that APOBEC3B, a key repressor of retrotransposons, is downregulated in senescent cells — unleashing LINE-1 activity and fueling genomic instability and aging.
🔗 doi.org/10.1186/s13100-025-00378-5
#Retrotransposons #APOBEC3B #Senescence #Aging
Antagonistic regulation of LINE-1/Alu elements and their repressor APOBEC3B in cellular senescence - Mobile DNA
Long Interspersed Nuclear Elements-1 (LINE-1 or L1) make up approximately 21% of the human genome, with some L1 loci containing intact open reading frames (ORFs) that facilitate retrotransposition. Be...
doi.org
October 24, 2025 at 3:04 PM
New paper out!
We show that APOBEC3B, a key repressor of retrotransposons, is downregulated in senescent cells — unleashing LINE-1 activity and fueling genomic instability and aging.
🔗 doi.org/10.1186/s13100-025-00378-5
#Retrotransposons #APOBEC3B #Senescence #Aging
We show that APOBEC3B, a key repressor of retrotransposons, is downregulated in senescent cells — unleashing LINE-1 activity and fueling genomic instability and aging.
🔗 doi.org/10.1186/s13100-025-00378-5
#Retrotransposons #APOBEC3B #Senescence #Aging
Did you know? Harpy Eagles (Harpia harpyja) have talons that are longer than grizzly bears’ claws. A new case report documents the first scientifically confirmed attack on an adult human: tinyurl.com/bdkdxuhc
📸 Givanildo Silva, via Wikimedia Commons (CC0)
#Birds #FeatheredFriday
📸 Givanildo Silva, via Wikimedia Commons (CC0)
#Birds #FeatheredFriday
October 24, 2025 at 10:05 AM
Did you know? Harpy Eagles (Harpia harpyja) have talons that are longer than grizzly bears’ claws. A new case report documents the first scientifically confirmed attack on an adult human: tinyurl.com/bdkdxuhc
📸 Givanildo Silva, via Wikimedia Commons (CC0)
#Birds #FeatheredFriday
📸 Givanildo Silva, via Wikimedia Commons (CC0)
#Birds #FeatheredFriday
Reposted by Daniel Sauter
We asked 3,785 PhD students across 107 countries about their experiences. Where do you think the happiest doctoral candidates were?
go.nature.com/3Wzz2lL
go.nature.com/3Wzz2lL
Are these the happiest PhD students in the world?
Brazil, Australia and Italy have the highest satisfaction scores in Nature’s global 2025 PhD survey — but are these nations really the best places to do a doctorate?
go.nature.com
October 20, 2025 at 3:05 PM
We asked 3,785 PhD students across 107 countries about their experiences. Where do you think the happiest doctoral candidates were?
go.nature.com/3Wzz2lL
go.nature.com/3Wzz2lL
Reposted by Daniel Sauter
SARS-CoV-2 delta and omicron variants alter trophoblast cell fusion and syncytiotrophoblast dynamics: new insights into placental vulnerability
www.nature.com/articles/s41...
www.nature.com/articles/s41...
SARS-CoV-2 delta and omicron variants alter trophoblast cell fusion and syncytiotrophoblast dynamics: new insights into placental vulnerability - Cell Death & Disease
Cell Death & Disease - SARS-CoV-2 delta and omicron variants alter trophoblast cell fusion and syncytiotrophoblast dynamics: new insights into placental vulnerability
www.nature.com
October 7, 2025 at 3:01 PM
SARS-CoV-2 delta and omicron variants alter trophoblast cell fusion and syncytiotrophoblast dynamics: new insights into placental vulnerability
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Daniel Sauter
Nature research paper: A human-specific regulatory mechanism revealed in a pre-implantation model
go.nature.com/4o2TgQs
go.nature.com/4o2TgQs
A human-specific regulatory mechanism revealed in a pre-implantation model - Nature
Genetic manipulation of blastoids reveals the role of recently emerged transposable elements and genes in human development.
go.nature.com
October 2, 2025 at 5:49 PM
Nature research paper: A human-specific regulatory mechanism revealed in a pre-implantation model
go.nature.com/4o2TgQs
go.nature.com/4o2TgQs
Reposted by Daniel Sauter
#MicrobiologyMonday: Can bird song shape your microbiome? 🐦Scientists propose that interactions with nature may influence gut microbiome composition, suggesting it is shaped not just by direct microbial exposure, but by multisensory experiences. #mSystem asm.social/2Cx
September 29, 2025 at 2:11 PM
#MicrobiologyMonday: Can bird song shape your microbiome? 🐦Scientists propose that interactions with nature may influence gut microbiome composition, suggesting it is shaped not just by direct microbial exposure, but by multisensory experiences. #mSystem asm.social/2Cx
Reposted by Daniel Sauter
New paper alert 🎉
We explore the origins of deltaviruses and find they have infected and co-evolved with termites for 141 million years 🐜🕑🦴
This was a fascinating story to work on with @ariskatzourakis.bsky.social, Jose Gabriel and @anselmojiro.bsky.social
www.sciencedirect.com/science/arti...
We explore the origins of deltaviruses and find they have infected and co-evolved with termites for 141 million years 🐜🕑🦴
This was a fascinating story to work on with @ariskatzourakis.bsky.social, Jose Gabriel and @anselmojiro.bsky.social
www.sciencedirect.com/science/arti...
Endogenous viral elements in termite genomes reveal extensive diversity of deltaviruses and provide insights into their origins
Deltaviruses are subviral agents of animals, which, in humans, require a hepadnavirus helper for transmission. The absence of deltavirus-like endogeno…
www.sciencedirect.com
September 15, 2025 at 11:16 AM
New paper alert 🎉
We explore the origins of deltaviruses and find they have infected and co-evolved with termites for 141 million years 🐜🕑🦴
This was a fascinating story to work on with @ariskatzourakis.bsky.social, Jose Gabriel and @anselmojiro.bsky.social
www.sciencedirect.com/science/arti...
We explore the origins of deltaviruses and find they have infected and co-evolved with termites for 141 million years 🐜🕑🦴
This was a fascinating story to work on with @ariskatzourakis.bsky.social, Jose Gabriel and @anselmojiro.bsky.social
www.sciencedirect.com/science/arti...
Reposted by Daniel Sauter
Do you research endogenous retroviruses (ERVs) or want to learn more about them? 🧬🤔
Consider presenting at or attending AuusiERV - an inaugural online symposium for ERV research in Australia 🇦🇺 (and abroad) 🗺️
Abstracts due 1st October!
events.humanitix.com/aussierv-2025
#ERV #retrovirus
Consider presenting at or attending AuusiERV - an inaugural online symposium for ERV research in Australia 🇦🇺 (and abroad) 🗺️
Abstracts due 1st October!
events.humanitix.com/aussierv-2025
#ERV #retrovirus
AussiERV 2025
AussiERV: Australia’s first symposium dedicated to endogenous retroviruses. Join us for this one-day virtual event on November 7th!
events.humanitix.com
September 27, 2025 at 7:28 AM
Do you research endogenous retroviruses (ERVs) or want to learn more about them? 🧬🤔
Consider presenting at or attending AuusiERV - an inaugural online symposium for ERV research in Australia 🇦🇺 (and abroad) 🗺️
Abstracts due 1st October!
events.humanitix.com/aussierv-2025
#ERV #retrovirus
Consider presenting at or attending AuusiERV - an inaugural online symposium for ERV research in Australia 🇦🇺 (and abroad) 🗺️
Abstracts due 1st October!
events.humanitix.com/aussierv-2025
#ERV #retrovirus
Reposted by Daniel Sauter
Nicht alle Viren machen uns krank, tatsächlich nur ein ganz kleiner Teil von ihnen. Andere leben auf und in uns, und manche sind sogar fester Bestandteil unseres Erbguts!
Ein Einblick in die vielen Facetten der Virologie bei @quarkswdr.bsky.social:
www.ardmediathek.de/video/Y3JpZD...
Ein Einblick in die vielen Facetten der Virologie bei @quarkswdr.bsky.social:
www.ardmediathek.de/video/Y3JpZD...
Quarks: Viren: Freund und Feind! - hier anschauen
Viren gelten als Auslöser von Krankheiten und Pandemien. Doch das ist nur ein Teil der Wahrheit. Seit Milliarden Jahren wirken sie auch als Motor der Evolution. Rund acht Prozent unseres menschlichen ...
www.ardmediathek.de
September 26, 2025 at 9:44 AM
Nicht alle Viren machen uns krank, tatsächlich nur ein ganz kleiner Teil von ihnen. Andere leben auf und in uns, und manche sind sogar fester Bestandteil unseres Erbguts!
Ein Einblick in die vielen Facetten der Virologie bei @quarkswdr.bsky.social:
www.ardmediathek.de/video/Y3JpZD...
Ein Einblick in die vielen Facetten der Virologie bei @quarkswdr.bsky.social:
www.ardmediathek.de/video/Y3JpZD...
Did you know? The Secretary bird (Sagittarius serpentarius) is named after the long feathers on its head, resembling quill pens tucked behind a secretary’s ear. It hunts snakes by stomping on them with its powerful feet. 📸 Hobbyfotowiki, via Wikimedia Commons (CC0)
#Birds #FeatheredFriday
#Birds #FeatheredFriday
September 26, 2025 at 7:56 AM
Did you know? The Secretary bird (Sagittarius serpentarius) is named after the long feathers on its head, resembling quill pens tucked behind a secretary’s ear. It hunts snakes by stomping on them with its powerful feet. 📸 Hobbyfotowiki, via Wikimedia Commons (CC0)
#Birds #FeatheredFriday
#Birds #FeatheredFriday
Reposted by Daniel Sauter
A new analysis of individuals living with HIV reveals key sex differences in innate immune profiles and the complexity of the HIV proviral reservoir.
Read more in #ScienceTranslationalMedicine: https://scim.ag/4mridnp
Read more in #ScienceTranslationalMedicine: https://scim.ag/4mridnp
Sex differences in HIV-1 reservoir cell selection are linked to altered innate immune profiles
Sex-specific differences in immune selection of HIV-1 reservoir cells during long-term antiretroviral therapy are driven by innate immunity.
scim.ag
September 22, 2025 at 6:00 PM
A new analysis of individuals living with HIV reveals key sex differences in innate immune profiles and the complexity of the HIV proviral reservoir.
Read more in #ScienceTranslationalMedicine: https://scim.ag/4mridnp
Read more in #ScienceTranslationalMedicine: https://scim.ag/4mridnp
Reposted by Daniel Sauter
Check out our new paper 🎉. Thanks to everyone who was involved 🙏🏻.
My first postdoc paper in @m-vincendeau.bsky.social lab is out in Frontiers in Immunology.🥳
We identified that hepatitis viruses, especially HBV, upregulate specific human endogenous retrovirus (HERV) groups that are linked with autoimmune diseases.
doi.org/10.3389/fimm...
We identified that hepatitis viruses, especially HBV, upregulate specific human endogenous retrovirus (HERV) groups that are linked with autoimmune diseases.
doi.org/10.3389/fimm...
Frontiers | HERV-K10 as a mediator of immune modulation in hepatitis infections
The human genome contains ~8% of endogenous retroviruses (HERVs), whose reactivation has been implicated in diseases such as cancer and autoimmune disorders....
doi.org
September 23, 2025 at 7:47 PM
Check out our new paper 🎉. Thanks to everyone who was involved 🙏🏻.
Leider wurden die endogenen Retroviren mal wieder vergessen…
Die machen rund 8% unseres Genoms aus. Rechnet man das auf alle Zellen hoch, schleppt jeder Mensch (ganz grob) etwa 15 g virale DNA täglich mit sich herum. Das entspricht immerhin fünf Stück Würfelzucker!
Die machen rund 8% unseres Genoms aus. Rechnet man das auf alle Zellen hoch, schleppt jeder Mensch (ganz grob) etwa 15 g virale DNA täglich mit sich herum. Das entspricht immerhin fünf Stück Würfelzucker!
Verrückter Fakt des Tages: #vfdt
Alle Viren dieser Erde haben gut dreimal so viel Biomasse wie alle Menschen dieser Erde.
Alle Viren dieser Erde haben gut dreimal so viel Biomasse wie alle Menschen dieser Erde.
September 23, 2025 at 4:59 PM
Leider wurden die endogenen Retroviren mal wieder vergessen…
Die machen rund 8% unseres Genoms aus. Rechnet man das auf alle Zellen hoch, schleppt jeder Mensch (ganz grob) etwa 15 g virale DNA täglich mit sich herum. Das entspricht immerhin fünf Stück Würfelzucker!
Die machen rund 8% unseres Genoms aus. Rechnet man das auf alle Zellen hoch, schleppt jeder Mensch (ganz grob) etwa 15 g virale DNA täglich mit sich herum. Das entspricht immerhin fünf Stück Würfelzucker!
Reposted by Daniel Sauter
Brazil hopes to turn the tide of dengue with a home-grown vaccine and an army of mosquitoes
go.nature.com/4pveeJf
go.nature.com/4pveeJf
How billions of hacked mosquitoes and a vaccine could beat the deadly dengue virus
Outbreaks of dengue are killing thousands of people in South America each year and getting worse. Brazil hopes to turn the tide with a home-grown vaccine and an army of mosquitoes infected with Wolbachia bacteria.
go.nature.com
September 20, 2025 at 1:48 PM
Brazil hopes to turn the tide of dengue with a home-grown vaccine and an army of mosquitoes
go.nature.com/4pveeJf
go.nature.com/4pveeJf
Reposted by Daniel Sauter
Highlights of this year’s Ig Nobel recipients include a nutrition prize for studying the preferred pizza toppings of rainbow lizards at a seaside resort in Togo
go.nature.com/4n5HQv7
go.nature.com/4n5HQv7
Tipsy bats and perfect pasta: Ig Nobels celebrate ‘improbable’ research
The annual awards are a celebration of weird but thought-provoking science.
go.nature.com
September 19, 2025 at 9:27 AM
Highlights of this year’s Ig Nobel recipients include a nutrition prize for studying the preferred pizza toppings of rainbow lizards at a seaside resort in Togo
go.nature.com/4n5HQv7
go.nature.com/4n5HQv7
Reposted by Daniel Sauter
Scientists have created the first ever viruses designed by AI, and they’re capable of hunting down and killing strains of E. coli
go.nature.com/3Khz3aR
go.nature.com/3Khz3aR
World's first AI-designed viruses a step towards AI-generated life
Scientists used AI to write coherent viral genomes, using them to synthesize bacteriophages capable of killing resistant strains of bacteria.
go.nature.com
September 19, 2025 at 12:48 PM
Scientists have created the first ever viruses designed by AI, and they’re capable of hunting down and killing strains of E. coli
go.nature.com/3Khz3aR
go.nature.com/3Khz3aR
Did you know? The Kauaʻi ʻōʻō (Moho braccatus), once native to Hawaii, is most likely extinct. This bird was famous for its haunting love song. Listen to the last singing male recorded in 1987: tinyurl.com/2w4kuz2z. 📸 Robert Shallenberger, via Wikimedia Commons (CC0)
#Birds #FeatheredFriday
#Birds #FeatheredFriday
September 19, 2025 at 4:12 PM
Did you know? The Kauaʻi ʻōʻō (Moho braccatus), once native to Hawaii, is most likely extinct. This bird was famous for its haunting love song. Listen to the last singing male recorded in 1987: tinyurl.com/2w4kuz2z. 📸 Robert Shallenberger, via Wikimedia Commons (CC0)
#Birds #FeatheredFriday
#Birds #FeatheredFriday
Reposted by Daniel Sauter
PIWI clade Argonautes are essential for transposon silencing. Without them, animals are sterile due to massive transposon activity.
But how does piRNA-guided target interaction translate into silencing?
PhD student Júlia Portell Montserrat has an intriguing answer
www.cell.com/molecular-ce...
But how does piRNA-guided target interaction translate into silencing?
PhD student Júlia Portell Montserrat has an intriguing answer
www.cell.com/molecular-ce...
September 17, 2025 at 10:39 AM
PIWI clade Argonautes are essential for transposon silencing. Without them, animals are sterile due to massive transposon activity.
But how does piRNA-guided target interaction translate into silencing?
PhD student Júlia Portell Montserrat has an intriguing answer
www.cell.com/molecular-ce...
But how does piRNA-guided target interaction translate into silencing?
PhD student Júlia Portell Montserrat has an intriguing answer
www.cell.com/molecular-ce...
Did you know? Malleefowl (Leipoa ocellata) incubate their eggs in large mounds of rotting leaves. The male adjusts the mound daily to keep the temperature perfect. The chicks hatch fully independent and never meet their parents. 📸 melissadoherty, via Wikimedia Commons (CC0)
#Birds #FeatheredFriday
#Birds #FeatheredFriday
September 12, 2025 at 4:47 PM
Did you know? Malleefowl (Leipoa ocellata) incubate their eggs in large mounds of rotting leaves. The male adjusts the mound daily to keep the temperature perfect. The chicks hatch fully independent and never meet their parents. 📸 melissadoherty, via Wikimedia Commons (CC0)
#Birds #FeatheredFriday
#Birds #FeatheredFriday
Reposted by Daniel Sauter
Ich denke, Jörg Timm, Vizepräsident der GfV, spricht hier für viele Virologen: "Hat uns schon überrascht"
www.ndr.de/nachrichten/...
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www.ndr.de/nachrichten/...
(MB)
September 10, 2025 at 4:38 PM
Ich denke, Jörg Timm, Vizepräsident der GfV, spricht hier für viele Virologen: "Hat uns schon überrascht"
www.ndr.de/nachrichten/...
(MB)
www.ndr.de/nachrichten/...
(MB)