SALUVET
@saluvetucm.bsky.social
Official account of the SALUVET research group (saluvet.com)
Located at the Faculty of Veterinary Science, Complutense University of Madrid, Spain
Our spinoff http://saluvetinnova.com
Want to become a parasite expert? http://parasitxpert.es
Located at the Faculty of Veterinary Science, Complutense University of Madrid, Spain
Our spinoff http://saluvetinnova.com
Want to become a parasite expert? http://parasitxpert.es
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SALUVET
@saluvetucm.bsky.social
· Nov 18
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🐮🐑🔬🧬🧪We just arrived in Bluesky. You can also follow us on X, formerly Twitter (twitter.com/SALUVET_UCM), LinkedIn (www.linkedin.com/in/saluvet-g...), Instagram (www.instagram.com/saluvetucm/p...) and Facebook (www.facebook.com/SALUVETUCM/)
It took a while, but it is finally out 🥳.
frontiersin.org/journals/imm...
Pioneering work by Yanina Hecker where two novel sheep macrophages were characterized in vitro: M and GM-macrophages 🔬. (1/3)
frontiersin.org/journals/imm...
Pioneering work by Yanina Hecker where two novel sheep macrophages were characterized in vitro: M and GM-macrophages 🔬. (1/3)
Frontiers | Ovine macrophage identity and plasticity: novel insights into CSF-driven polarization and species-specific responses
Macrophages (MØs) are pivotal immune cells exhibiting significant plasticity that has been widely studied in human and murine models. Granulocyte-macrophage ...
frontiersin.org
November 25, 2025 at 4:37 PM
It took a while, but it is finally out 🥳.
frontiersin.org/journals/imm...
Pioneering work by Yanina Hecker where two novel sheep macrophages were characterized in vitro: M and GM-macrophages 🔬. (1/3)
frontiersin.org/journals/imm...
Pioneering work by Yanina Hecker where two novel sheep macrophages were characterized in vitro: M and GM-macrophages 🔬. (1/3)
Let's celebrate! 🥳We have a new doctor with us. Andrea Largo de la Torre did an excellent job with her thesis dissertation about Toxoplasma vaccine development and a pig animal model👌. Congratulations Andrea👏
November 13, 2025 at 12:32 PM
Let's celebrate! 🥳We have a new doctor with us. Andrea Largo de la Torre did an excellent job with her thesis dissertation about Toxoplasma vaccine development and a pig animal model👌. Congratulations Andrea👏
We tried a Toxoplasma inactivated multistage vaccine in pigs. It showed to be safe and immunogenic, and able to reduce tissue cyst formation. rdcu.be/eNAau
An inactivated vaccine against acquired Toxoplasma gondii infection in pigs as a tool to minimize the zoonotic transmission risk
rdcu.be
November 2, 2025 at 7:46 PM
We tried a Toxoplasma inactivated multistage vaccine in pigs. It showed to be safe and immunogenic, and able to reduce tissue cyst formation. rdcu.be/eNAau
In this work our collaborators from Bern show that genetic manipulation in T. gondii can lead to system-wide proteomic shifts in both parasite and host, emphasizing the need for cautious interpretation of knock-out-based functional analyses www.mdpi.com/3561368 #mdpiijms
www.mdpi.com
October 27, 2025 at 9:11 PM
In this work our collaborators from Bern show that genetic manipulation in T. gondii can lead to system-wide proteomic shifts in both parasite and host, emphasizing the need for cautious interpretation of knock-out-based functional analyses www.mdpi.com/3561368 #mdpiijms
New insights on toxoplasmosis in sheep. In this paper we analyze the tropism of the parasite for different organs based on the dose of infection and further validate the efficacy of BKI-1748 in preventing the establishment of chronic infection. doi.org/10.1016/j.fa...
Redirecting
doi.org
October 27, 2025 at 8:57 PM
New insights on toxoplasmosis in sheep. In this paper we analyze the tropism of the parasite for different organs based on the dose of infection and further validate the efficacy of BKI-1748 in preventing the establishment of chronic infection. doi.org/10.1016/j.fa...
Check out our new paper where we delve into the molecular mechanisms underlying N. caninum virulence. NcBPK1 seems to be involved in parasite virulence and cyst formation. Find out more here 👇
rdcu.be/eMdoO
rdcu.be/eMdoO
Loss of NcBPK1 impairs bradyzoite differentiation and enhances virulence in Neospora caninum | Parasites & Vectors
rdcu.be
October 22, 2025 at 4:10 PM
Check out our new paper where we delve into the molecular mechanisms underlying N. caninum virulence. NcBPK1 seems to be involved in parasite virulence and cyst formation. Find out more here 👇
rdcu.be/eMdoO
rdcu.be/eMdoO
Yet another proof that lab-culture adaptation in #Toxoplasma produces not only phenotypic changes but also proteomic in a short span of time. Great work by J. Regidor, @davarrsol.bsky.social, R. Calero and LM. Ortega in collaboration with Hemphill's lab. www.frontiersin.org/journals/cel...
Frontiers | Proteome changes during in vitro culture adaptation of Toxoplasma gondii archetypal II and III field isolates
IntroductionRapid in vitro culture adaptation of recently obtained Toxoplasma gondii isolates leading to deep changes in relevant phenotypic traits has been ...
www.frontiersin.org
September 16, 2025 at 6:07 AM
Yet another proof that lab-culture adaptation in #Toxoplasma produces not only phenotypic changes but also proteomic in a short span of time. Great work by J. Regidor, @davarrsol.bsky.social, R. Calero and LM. Ortega in collaboration with Hemphill's lab. www.frontiersin.org/journals/cel...
Reposted by SALUVET
Great work by Devinn Sinnott and Karen Shapiro at @ucdavisvetmed.bsky.social : dx.plos.org/10.1371/jour...
Fatal Toxoplasma gondii COUG strain infections in southern sea otters (Enhydra lutris nereis): New insight on contributing factors and parasite serotyping
Fatal infections with the rare COUG strain of the zoonotic parasite Toxoplasma gondii were recently detected for the first time in four southern sea otters (Enhydra lutris nereis) exhibiting severe pr...
dx.plos.org
September 12, 2025 at 10:28 AM
Great work by Devinn Sinnott and Karen Shapiro at @ucdavisvetmed.bsky.social : dx.plos.org/10.1371/jour...
Reposted by SALUVET
Cool paper by Nicole Hryckowian at Laura Knoll's lab!Fibroblasts enhance the growth and survival of adult feline small intestinal organoids | mSphere journals.asm.org/doi/10.1128/...
Fibroblasts enhance the growth and survival of adult feline small intestinal organoids | mSphere
Many microbial pathogens are acquired orally through contaminated food or water. Being
able to model these infections in cell culture has been greatly enhanced by the development
of intestinal organoi...
journals.asm.org
September 12, 2025 at 11:15 AM
Cool paper by Nicole Hryckowian at Laura Knoll's lab!Fibroblasts enhance the growth and survival of adult feline small intestinal organoids | mSphere journals.asm.org/doi/10.1128/...
Check out our new paper on Neospora caninum, where we investigate NcROP2 as a key virulence factor involved in immune evasion and parasite proliferation in vitro and in vivo.
www.frontiersin.org/journals/imm...
www.frontiersin.org/journals/imm...
Frontiers | NcROP2 deletion reduces Neospora caninum virulence by altering parasite stage differentiation and hijacking host immune response
IntroductionNeospora caninum is an apicomplexan parasite responsible for bovine neosporosis, a major cause of abortion in cattle worldwide. N. caninum rhoptr...
www.frontiersin.org
August 16, 2025 at 10:07 AM
Check out our new paper on Neospora caninum, where we investigate NcROP2 as a key virulence factor involved in immune evasion and parasite proliferation in vitro and in vivo.
www.frontiersin.org/journals/imm...
www.frontiersin.org/journals/imm...
Reposted by SALUVET
La tesis sobre Campilobacteriosis genital bovina en España de Nerea Pena de #NEIKER obtiene la calificación de Sobresaliente Cum laude
@ucm.es @saluvetucm.bsky.social
@ucm.es @saluvetucm.bsky.social
La tesis sobre Campilobacteriosis genital bovina en España de Nerea Pena obtiene la calificación de Sobresaliente Cum laude
La campilobacteriosis genital bovina (CGB) es una enfermedad de transmisión sexual (ETS) causada por Campylobacter fetus subespecie venerealis (Cfv) y el biotipo intermedius (Cfvi), que curs ...
bit.ly
July 21, 2025 at 7:25 AM
La tesis sobre Campilobacteriosis genital bovina en España de Nerea Pena de #NEIKER obtiene la calificación de Sobresaliente Cum laude
@ucm.es @saluvetucm.bsky.social
@ucm.es @saluvetucm.bsky.social
En un mundo globalizado, la salud humana, animal y ambiental están más conectadas que nunca. Sigue el encuentro para hablar del concepto #OneHealth entre nuestro director Luis Miguel Ortega Mora y María José Gómez-Yubero. cienciaensociedad.com/one-health-y...
“One Health” y sus principales retos emergentes: Encuentro con Luis Ortega Mora y María José Gómez-Yubero - Ciencia en Sociedad
En un mundo globalizado, la salud humana, animal y ambiental están más conectadas que nunca. El enfoque One Health propone una visión integral para afrontar retos como las pandemias, el cambio climáti...
cienciaensociedad.com
July 12, 2025 at 3:12 PM
En un mundo globalizado, la salud humana, animal y ambiental están más conectadas que nunca. Sigue el encuentro para hablar del concepto #OneHealth entre nuestro director Luis Miguel Ortega Mora y María José Gómez-Yubero. cienciaensociedad.com/one-health-y...
Check it out! In this work we describe the early dynamics of Toxoplasma infection in pregnant sheep using a natural route of infection (oral oocysts). First stone in the understanding of the mechanisms behind early abortions occurring during the acute phase of toxoplasmosis. rdcu.be/euqfI
Early dynamics of Toxoplasma gondii infection in sheep inoculated at mid-gestation with archetypal type II oocysts
rdcu.be
July 2, 2025 at 7:05 AM
Check it out! In this work we describe the early dynamics of Toxoplasma infection in pregnant sheep using a natural route of infection (oral oocysts). First stone in the understanding of the mechanisms behind early abortions occurring during the acute phase of toxoplasmosis. rdcu.be/euqfI
Salimos en la prensa mostrando los resultados de nuestro reciente estudio de ensaladas listas para consumo y la presencia de Toxoplasma (doi.
org/10.2807/1560-7917.ES.2025.30.22.2400594) elpais.com/sociedad/202...
org/10.2807/1560-7917.ES.2025.30.22.2400594) elpais.com/sociedad/202...
Un gran estudio europeo detecta el parásito de la toxoplasmosis en una de cada 25 ensaladas en bolsa
Médicos y expertos recomiendan a mujeres embarazadas y pacientes inmunodeprimidos lavar siempre bien estas y otras verduras que se consuman crudas
elpais.com
June 17, 2025 at 6:56 AM
Salimos en la prensa mostrando los resultados de nuestro reciente estudio de ensaladas listas para consumo y la presencia de Toxoplasma (doi.
org/10.2807/1560-7917.ES.2025.30.22.2400594) elpais.com/sociedad/202...
org/10.2807/1560-7917.ES.2025.30.22.2400594) elpais.com/sociedad/202...
Finally out! After a great deal of collaborative work, we present the results of the Eurosurvey of ready-to-eat salad mixes and the molecular detection of Toxoplasma gondii. Find out more here 👇
www.eurosurveillance.org/content/10.2...
www.eurosurveillance.org/content/10.2...
Molecular detection of Toxoplasma gondii in ready-to-eat salad mixes: multi-country survey using a validated and harmonised standard operating procedure, Europe, 2021 to 2022
Background
Most Toxoplasma gondii infections in humans are considered foodborne, but the relative importance of the various routes of infection is largely unknown. Consumption of green produce contami...
www.eurosurveillance.org
June 17, 2025 at 6:48 AM
Finally out! After a great deal of collaborative work, we present the results of the Eurosurvey of ready-to-eat salad mixes and the molecular detection of Toxoplasma gondii. Find out more here 👇
www.eurosurveillance.org/content/10.2...
www.eurosurveillance.org/content/10.2...
The paper “An early treatment with BKI-1748 exhibits full protection against abortion and congenital infection in sheep experimentally infected with Toxoplasma gondii." by Roberto Sanchez-Sanchez published on JID (doi.org/10.1093/infd...) got the attention of Prof. Heller at UC Davis SVM.
An Early Treatment With BKI-1748 Exhibits Full Protection Against Abortion and Congenital Infection in Sheep Experimentally Infected With Toxoplasma gondii
Toxoplasmosis is a zoonotic disease and the first-line treatments for congenital Toxoplasma gondii infections in humans lack sufficient safety and efficacy
doi.org
June 3, 2025 at 9:08 PM
The paper “An early treatment with BKI-1748 exhibits full protection against abortion and congenital infection in sheep experimentally infected with Toxoplasma gondii." by Roberto Sanchez-Sanchez published on JID (doi.org/10.1093/infd...) got the attention of Prof. Heller at UC Davis SVM.
New paper out! We design a new murine model of oral infection with oocysts from a recently obtained Type III isolate, TgShSp24. This novel model better mimic natural infection and provides a valuable tool for testing drugs and vaccines. rdcu.be/egFjv
Characterization of a novel murine model of Toxoplasma gondii infection using oocysts of a recently obtained Type III isolate | Veterinary Research
rdcu.be
April 7, 2025 at 6:58 AM
New paper out! We design a new murine model of oral infection with oocysts from a recently obtained Type III isolate, TgShSp24. This novel model better mimic natural infection and provides a valuable tool for testing drugs and vaccines. rdcu.be/egFjv
Ayer finalizamos las clases de Sanidad de rumiantes en el máster de Producción y Sanidad Animal con la presentación de los trabajos por parte de los estudiantes.
April 2, 2025 at 6:23 AM
Ayer finalizamos las clases de Sanidad de rumiantes en el máster de Producción y Sanidad Animal con la presentación de los trabajos por parte de los estudiantes.
New paper out where we describe the presence of Besnoitia species in opossums from Florida and Brazil.
doi.org/10.1638/2024...
doi.org/10.1638/2024...
ANTIBODIES TO BESNOITIA SPP. IN THREE SPECIES OF FREERANGING OPOSSUM (DIDELPHIS SPP.) IN FLORIDA, USA, AND BRAZIL
The opossum has been recognized as an intermediate host for many parasites including Besnoitia spp., which is a protozoan that infects various mammals, including many wildlife species. A limited numbe...
doi.org
March 14, 2025 at 8:03 AM
New paper out where we describe the presence of Besnoitia species in opossums from Florida and Brazil.
doi.org/10.1638/2024...
doi.org/10.1638/2024...
JOB ALERT! 🚨Estamos buscando un candidat@ para la contratación de Jóvenes Investigadores de la Comunidad de Madrid 2024: www.ucm.es/ct9-25
REQUISITOS: tener titulación con Grado en el área de conocimiento Sanidad Y estar apuntado al paro.
REQUISITOS: tener titulación con Grado en el área de conocimiento Sanidad Y estar apuntado al paro.
CT9/25 | Universidad Complutense de Madrid
UNIVERSIDAD COMPLUTENSE DE MADRID. Convocatoria para la contratación de 10 personas como personal técnico, investigador, tecnólogas, personal técnico y otros perfiles profesionales en I+D+I para joven...
www.ucm.es
January 22, 2025 at 4:09 PM
JOB ALERT! 🚨Estamos buscando un candidat@ para la contratación de Jóvenes Investigadores de la Comunidad de Madrid 2024: www.ucm.es/ct9-25
REQUISITOS: tener titulación con Grado en el área de conocimiento Sanidad Y estar apuntado al paro.
REQUISITOS: tener titulación con Grado en el área de conocimiento Sanidad Y estar apuntado al paro.
New paper out in a great collaborative effort between groups in Spain. Sierra Nevada Iberian ibexes🐐are Toxoplasma and Neospora seronegative, fitting the eco-epidemiological features of Mediterranean mountainous areas ⛰️. Link below 👇https://www.sciencedirect.com/science/article/pii/S0034528825000049
January 12, 2025 at 9:21 AM
New paper out in a great collaborative effort between groups in Spain. Sierra Nevada Iberian ibexes🐐are Toxoplasma and Neospora seronegative, fitting the eco-epidemiological features of Mediterranean mountainous areas ⛰️. Link below 👇https://www.sciencedirect.com/science/article/pii/S0034528825000049
We recently showed that BKI-1748 is a very promising drug that effectively prevents abortion and vertical transmission of Toxoplasma when administered 2 days post-infection in pregnant sheep.
January 7, 2025 at 7:10 PM
We recently showed that BKI-1748 is a very promising drug that effectively prevents abortion and vertical transmission of Toxoplasma when administered 2 days post-infection in pregnant sheep.
We had a wonderful time at the SALUVET Xmas party and custom contest🎄🎅🏼. Congratulations to Ana Huertas López who earned a very well deserved first prize entitling her to a free lunch😄👏🏼
December 12, 2024 at 8:41 AM
We had a wonderful time at the SALUVET Xmas party and custom contest🎄🎅🏼. Congratulations to Ana Huertas López who earned a very well deserved first prize entitling her to a free lunch😄👏🏼
Last week at Saluvet, we had the pleasure of having a seminar given by our PhD student,
@RafaelAmieva
. During his presentation, he shared insights from his doctoral stays at Dr. Musa Hassan's lab at the Roslin Institute in Edinburgh, Scotland.
@RafaelAmieva
. During his presentation, he shared insights from his doctoral stays at Dr. Musa Hassan's lab at the Roslin Institute in Edinburgh, Scotland.
December 7, 2024 at 11:25 AM
Last week at Saluvet, we had the pleasure of having a seminar given by our PhD student,
@RafaelAmieva
. During his presentation, he shared insights from his doctoral stays at Dr. Musa Hassan's lab at the Roslin Institute in Edinburgh, Scotland.
@RafaelAmieva
. During his presentation, he shared insights from his doctoral stays at Dr. Musa Hassan's lab at the Roslin Institute in Edinburgh, Scotland.
Updated picture of SALUVET members, November 2024!🍂🥼
December 6, 2024 at 7:55 PM
Updated picture of SALUVET members, November 2024!🍂🥼