Jose Miguel Ramirez
@ramirezjmiguel.bsky.social
PhD in Bioinformatics | Transcriptomics, Genetics, Epigenetics and Data Science
Reposted by Jose Miguel Ramirez
1/ Everything that could go wrong in paper publishing… did.
A story of patience, absurdity, and persistence 🌀 <1min
From Alfonso Valencia’s lab and a very stubborn PhD student (me).
A story of patience, absurdity, and persistence 🌀 <1min
From Alfonso Valencia’s lab and a very stubborn PhD student (me).
September 2, 2025 at 6:37 PM
1/ Everything that could go wrong in paper publishing… did.
A story of patience, absurdity, and persistence 🌀 <1min
From Alfonso Valencia’s lab and a very stubborn PhD student (me).
A story of patience, absurdity, and persistence 🌀 <1min
From Alfonso Valencia’s lab and a very stubborn PhD student (me).
Reposted by Jose Miguel Ramirez
🧬 I’m thrilled to share our latest publication in Genome Medicine, led by the brilliant @ramirezjmiguel.bsky.social :
“The molecular impact of cigarette smoking resembles aging across tissues”
👉 genomemedicine.biomedcentral.com/articles/10....
“The molecular impact of cigarette smoking resembles aging across tissues”
👉 genomemedicine.biomedcentral.com/articles/10....
The molecular impact of cigarette smoking resembles aging across tissues - Genome Medicine
Background Tobacco smoke is the main cause of preventable mortality worldwide. Smoking increases the risk of developing many diseases and has been proposed as an aging accelerator. Yet, the molecular ...
genomemedicine.biomedcentral.com
June 4, 2025 at 8:43 AM
🧬 I’m thrilled to share our latest publication in Genome Medicine, led by the brilliant @ramirezjmiguel.bsky.social :
“The molecular impact of cigarette smoking resembles aging across tissues”
👉 genomemedicine.biomedcentral.com/articles/10....
“The molecular impact of cigarette smoking resembles aging across tissues”
👉 genomemedicine.biomedcentral.com/articles/10....
Reposted by Jose Miguel Ramirez
🔴Nuevo estudio del BSC y @Universidade do Porto revela que fumar 🚬 imita y acelera el envejecimiento en muchos tejidos del cuerpo humano
⭕Se trata del 1r análisis exhaustivo y multitejido que demuestra que el tabaquismo no sólo perjudica a órganos específicos
📄En Genome Medicine: bsc.es/Zt2
⭕Se trata del 1r análisis exhaustivo y multitejido que demuestra que el tabaquismo no sólo perjudica a órganos específicos
📄En Genome Medicine: bsc.es/Zt2
June 4, 2025 at 8:28 AM
🔴Nuevo estudio del BSC y @Universidade do Porto revela que fumar 🚬 imita y acelera el envejecimiento en muchos tejidos del cuerpo humano
⭕Se trata del 1r análisis exhaustivo y multitejido que demuestra que el tabaquismo no sólo perjudica a órganos específicos
📄En Genome Medicine: bsc.es/Zt2
⭕Se trata del 1r análisis exhaustivo y multitejido que demuestra que el tabaquismo no sólo perjudica a órganos específicos
📄En Genome Medicine: bsc.es/Zt2
Just got back from Milan after attending #ESHG2025. I had a great time presenting our poster and seeing so much interest in our preprint on calling rDNA variants: shorturl.at/p1D0C. Huge thanks to everyone who stopped by, asked questions, and shared insights. Let’s keep the conversation going! 🧬
May 28, 2025 at 2:03 PM
Just got back from Milan after attending #ESHG2025. I had a great time presenting our poster and seeing so much interest in our preprint on calling rDNA variants: shorturl.at/p1D0C. Huge thanks to everyone who stopped by, asked questions, and shared insights. Let’s keep the conversation going! 🧬
Check this new preprint on inter-individual DNA methylation variation, lead by the incredibly talented @oliveroswinona.bsky.social!!
Excited to share our new preprint: The impact of sex, age, and genetic ancestry on DNA methylation across tissues. Briefly, we explored how sex, age, and genetic ancestry shape DNA methylation across tissues and individuals. Want to know a bit more? Follow this “bluetorial”!
doi.org/10.1101/2025...
doi.org/10.1101/2025...
The impact of sex, age, and genetic ancestry on DNA methylation across tissues
Background: Understanding the consequences of individual DNA methylation variation is crucial for the study of human biology and disease. However, the collective impact of demographic traits on DNA me...
www.biorxiv.org
May 7, 2025 at 9:47 AM
Check this new preprint on inter-individual DNA methylation variation, lead by the incredibly talented @oliveroswinona.bsky.social!!
Reposted by Jose Miguel Ramirez
It's a beautiful spring day in Barcelona. Sunshine welcoming all our guests for the first day of the CRG's annual symposium! This year's theme is all about the mechanisms of gene expression.
April 24, 2025 at 8:56 AM
It's a beautiful spring day in Barcelona. Sunshine welcoming all our guests for the first day of the CRG's annual symposium! This year's theme is all about the mechanisms of gene expression.
Congratulations @oliveroswinona.bsky.social!!! A humongous amount of great work!! So proud and happy for you, even though you set the bar very high for the rest of us in the @melelab.bsky.social
Yesterday I defended my PhD thesis at the UB after nearly 5 years of work at the BSC @melelab.bsky.social. I couldn’t be happier! This wouldn’t have been possible without my amazing friends and fellow PhD students. 💘🎉
April 8, 2025 at 10:38 AM
Congratulations @oliveroswinona.bsky.social!!! A humongous amount of great work!! So proud and happy for you, even though you set the bar very high for the rest of us in the @melelab.bsky.social
Reposted by Jose Miguel Ramirez
Do you work in 💫human genetics💫?
Have you ever worried about what’s inside your gene annotation GTF⁉️
WELL, YOU SHOULD! 😱
Especially when studying a genetically diverse 🌍 cohort!
🔴We discover that gene annotations are European-biased 👉 impacting downstream analyses!
Don't miss this thread🧵⬇️
1/13
Have you ever worried about what’s inside your gene annotation GTF⁉️
WELL, YOU SHOULD! 😱
Especially when studying a genetically diverse 🌍 cohort!
🔴We discover that gene annotations are European-biased 👉 impacting downstream analyses!
Don't miss this thread🧵⬇️
1/13
Long-read transcriptomics of a diverse human cohort reveals widespread ancestry bias in gene annotation
Accurate gene annotations are fundamental for interpreting genetic variation, cellular function, and disease mechanisms. However, current human gene annotations are largely derived from transcriptomic...
www.biorxiv.org
March 20, 2025 at 1:20 PM
Do you work in 💫human genetics💫?
Have you ever worried about what’s inside your gene annotation GTF⁉️
WELL, YOU SHOULD! 😱
Especially when studying a genetically diverse 🌍 cohort!
🔴We discover that gene annotations are European-biased 👉 impacting downstream analyses!
Don't miss this thread🧵⬇️
1/13
Have you ever worried about what’s inside your gene annotation GTF⁉️
WELL, YOU SHOULD! 😱
Especially when studying a genetically diverse 🌍 cohort!
🔴We discover that gene annotations are European-biased 👉 impacting downstream analyses!
Don't miss this thread🧵⬇️
1/13
Reposted by Jose Miguel Ramirez
🚨New review paper alert!🚨
At the @rakyanlab.bsky.social, we have summarised what is currently known about genetic variation within the human ribosomal DNA and its potential consequences. Check it out if you are curious!!! Plenty of intriguing possibilities 😊
onlinelibrary.wiley.com/doi/10.1002/...
At the @rakyanlab.bsky.social, we have summarised what is currently known about genetic variation within the human ribosomal DNA and its potential consequences. Check it out if you are curious!!! Plenty of intriguing possibilities 😊
onlinelibrary.wiley.com/doi/10.1002/...
Assessing Human Ribosomal DNA Variation and Its Association With Phenotypic Outcomes
Genetic variation within the multi-copy, multi-locus ribosomal DNA (rDNA) can contribute to human complex trait variability. This variation takes the form of copy number, structural arrangement, and ....
onlinelibrary.wiley.com
January 21, 2025 at 7:39 AM
🚨New review paper alert!🚨
At the @rakyanlab.bsky.social, we have summarised what is currently known about genetic variation within the human ribosomal DNA and its potential consequences. Check it out if you are curious!!! Plenty of intriguing possibilities 😊
onlinelibrary.wiley.com/doi/10.1002/...
At the @rakyanlab.bsky.social, we have summarised what is currently known about genetic variation within the human ribosomal DNA and its potential consequences. Check it out if you are curious!!! Plenty of intriguing possibilities 😊
onlinelibrary.wiley.com/doi/10.1002/...
Thrilled to have hosted the inaugural PhD Afterwork event for the Life Sciences Department @bsc-cns.bsky.social yesterday! 🎉 Huge thanks to @aduesoba.bsky.social for being our inspiring first guest speaker. The event was a great success, and I can’t wait for the next one!
November 29, 2024 at 11:39 AM
Thrilled to have hosted the inaugural PhD Afterwork event for the Life Sciences Department @bsc-cns.bsky.social yesterday! 🎉 Huge thanks to @aduesoba.bsky.social for being our inspiring first guest speaker. The event was a great success, and I can’t wait for the next one!