Peio Azcoaga
@peioazcoaga.bsky.social
Postdoctoral researcher in breast cancer at https://caffarellab.com in @biogipuzkoa
Reposted by Peio Azcoaga
📣 It’s been a productive few days for our group!
💡Our new paper in 𝘊𝘦𝘭𝘭 𝘋𝘦𝘢𝘵𝘩 & 𝘋𝘪𝘴𝘦𝘢𝘴𝘦 shows that lead nitrate drives NRF2-dependent metabolic reprogramming and proliferation in hepatocytes.
With Università di Cagliari & Università di Torino, funded by MUR#PRIN2022.
🔗 www.nature.com/articles/s41...
💡Our new paper in 𝘊𝘦𝘭𝘭 𝘋𝘦𝘢𝘵𝘩 & 𝘋𝘪𝘴𝘦𝘢𝘴𝘦 shows that lead nitrate drives NRF2-dependent metabolic reprogramming and proliferation in hepatocytes.
With Università di Cagliari & Università di Torino, funded by MUR#PRIN2022.
🔗 www.nature.com/articles/s41...
Lead induces cell-autonomous proliferation and metabolic reprogramming of hepatocytes - Cell Death & Disease
Cell Death & Disease - Lead induces cell-autonomous proliferation and metabolic reprogramming of hepatocytes
www.nature.com
November 11, 2025 at 10:48 AM
📣 It’s been a productive few days for our group!
💡Our new paper in 𝘊𝘦𝘭𝘭 𝘋𝘦𝘢𝘵𝘩 & 𝘋𝘪𝘴𝘦𝘢𝘴𝘦 shows that lead nitrate drives NRF2-dependent metabolic reprogramming and proliferation in hepatocytes.
With Università di Cagliari & Università di Torino, funded by MUR#PRIN2022.
🔗 www.nature.com/articles/s41...
💡Our new paper in 𝘊𝘦𝘭𝘭 𝘋𝘦𝘢𝘵𝘩 & 𝘋𝘪𝘴𝘦𝘢𝘴𝘦 shows that lead nitrate drives NRF2-dependent metabolic reprogramming and proliferation in hepatocytes.
With Università di Cagliari & Università di Torino, funded by MUR#PRIN2022.
🔗 www.nature.com/articles/s41...
Reposted by Peio Azcoaga
Yet another great reason to live in Europe!!
Multilingualism protects against accelerated aging 😀
An analysis of aging in >86,000 participants across 27 European countries
Amoruso et al, Nature Aging 🧪⏳
www.nature.com/articles/s43...
Multilingualism protects against accelerated aging 😀
An analysis of aging in >86,000 participants across 27 European countries
Amoruso et al, Nature Aging 🧪⏳
www.nature.com/articles/s43...
November 10, 2025 at 7:51 PM
Yet another great reason to live in Europe!!
Multilingualism protects against accelerated aging 😀
An analysis of aging in >86,000 participants across 27 European countries
Amoruso et al, Nature Aging 🧪⏳
www.nature.com/articles/s43...
Multilingualism protects against accelerated aging 😀
An analysis of aging in >86,000 participants across 27 European countries
Amoruso et al, Nature Aging 🧪⏳
www.nature.com/articles/s43...
Reposted by Peio Azcoaga
Here is my weekly selection of #anticancer #therapy and #metabolic #reprogramming! Super interesting papers this issue (including our last study😂🤩😛) Enjoy! 🙏 @biomednews.bsky.social biomed.news/bims-meract/...
a man says i need you to pick one
ALT: a man says i need you to pick one
media.tenor.com
November 9, 2025 at 8:23 AM
Here is my weekly selection of #anticancer #therapy and #metabolic #reprogramming! Super interesting papers this issue (including our last study😂🤩😛) Enjoy! 🙏 @biomednews.bsky.social biomed.news/bims-meract/...
Reposted by Peio Azcoaga
This #WorldScienceDay we're celebrating the crucial role of cancer researchers' curiosity in driving life-saving developments 🤩🙌 magazine.eacr.org/keepresearch...
November 10, 2025 at 10:55 AM
This #WorldScienceDay we're celebrating the crucial role of cancer researchers' curiosity in driving life-saving developments 🤩🙌 magazine.eacr.org/keepresearch...
Reposted by Peio Azcoaga
Save the date!!! ⬇️
Register for Cancer Metabolism!
Join us in Bilbao to hear from top experts in the field discussing the metabolic alterations in tumours, the mechanisms through which metabolites regulate cell decisions and the metabolic interaction between the tumour and the host.
eacr.org/conference/c...
Join us in Bilbao to hear from top experts in the field discussing the metabolic alterations in tumours, the mechanisms through which metabolites regulate cell decisions and the metabolic interaction between the tumour and the host.
eacr.org/conference/c...
November 10, 2025 at 12:27 PM
Save the date!!! ⬇️
Reposted by Peio Azcoaga
How does the tumor microenvironment change as cancer progresses - & which cells appear, persist, or disappear along the way?
Excited to share our new study on the #TME answering this question!
Great collaboration with the Hausser lab 🧪🧬🔬
Open access link: www.cell.com/iscience/ful...
Read more ⏬
Excited to share our new study on the #TME answering this question!
Great collaboration with the Hausser lab 🧪🧬🔬
Open access link: www.cell.com/iscience/ful...
Read more ⏬
Study reveals dynamics of breast tumor microenvironment over time | Johanna Joyce posted on the topic | LinkedIn
How does the tumor microenvironment change as cancer progresses — and which cells appear, persist, or disappear along the way?
In this new study, a wonderful collaboration with Jean Hausser and his l...
www.linkedin.com
November 10, 2025 at 3:06 PM
How does the tumor microenvironment change as cancer progresses - & which cells appear, persist, or disappear along the way?
Excited to share our new study on the #TME answering this question!
Great collaboration with the Hausser lab 🧪🧬🔬
Open access link: www.cell.com/iscience/ful...
Read more ⏬
Excited to share our new study on the #TME answering this question!
Great collaboration with the Hausser lab 🧪🧬🔬
Open access link: www.cell.com/iscience/ful...
Read more ⏬
Reposted by Peio Azcoaga
Good Sunday, all. The weekly curated issue of papers in #cancermetabolism and #mitochondrialbiology is out, a concentrate of groundbreaking discoveries:
biomed.news/bims-camemi/...
@biomednews.bsky.social #keepreading
"There are years that ask questions and years that answer."-Zora Neale Hurston
biomed.news/bims-camemi/...
@biomednews.bsky.social #keepreading
"There are years that ask questions and years that answer."-Zora Neale Hurston
November 9, 2025 at 6:28 AM
Good Sunday, all. The weekly curated issue of papers in #cancermetabolism and #mitochondrialbiology is out, a concentrate of groundbreaking discoveries:
biomed.news/bims-camemi/...
@biomednews.bsky.social #keepreading
"There are years that ask questions and years that answer."-Zora Neale Hurston
biomed.news/bims-camemi/...
@biomednews.bsky.social #keepreading
"There are years that ask questions and years that answer."-Zora Neale Hurston
Reposted by Peio Azcoaga
We're campaigning to #KeepResearchCurious, championing basic research that can lead to unpredictable advances in science ✨
November 6, 2025 at 9:00 AM
We're campaigning to #KeepResearchCurious, championing basic research that can lead to unpredictable advances in science ✨
Reposted by Peio Azcoaga
🚨 Our new paper is now out in 𝘊𝘢𝘯𝘤𝘦𝘳 𝘙𝘦𝘴𝘦𝘢𝘳𝘤𝘩!
ESR1 mutations in ER⁺ breast cancer rewire lipid metabolism, creating a ferroptosis vulnerability 🔬
ACSL4 is a key biomarker & combo with SERDs offers a new strategy.
👏 Congrats to the whole #TBTlab & collaborators!
aacrjournals.org/cancerres/ar...
ESR1 mutations in ER⁺ breast cancer rewire lipid metabolism, creating a ferroptosis vulnerability 🔬
ACSL4 is a key biomarker & combo with SERDs offers a new strategy.
👏 Congrats to the whole #TBTlab & collaborators!
aacrjournals.org/cancerres/ar...
ESR1 Activating Mutations Confer Metabolic Vulnerabilities in ER+ Breast Cancer
Abstract. Endocrine therapy (ET) is the standard of care for estrogen receptor-positive (ER+) breast cancer. Point mutations in the ligand-binding domain of the gene encoding the estrogen receptor (ES...
aacrjournals.org
November 7, 2025 at 8:20 PM
🚨 Our new paper is now out in 𝘊𝘢𝘯𝘤𝘦𝘳 𝘙𝘦𝘴𝘦𝘢𝘳𝘤𝘩!
ESR1 mutations in ER⁺ breast cancer rewire lipid metabolism, creating a ferroptosis vulnerability 🔬
ACSL4 is a key biomarker & combo with SERDs offers a new strategy.
👏 Congrats to the whole #TBTlab & collaborators!
aacrjournals.org/cancerres/ar...
ESR1 mutations in ER⁺ breast cancer rewire lipid metabolism, creating a ferroptosis vulnerability 🔬
ACSL4 is a key biomarker & combo with SERDs offers a new strategy.
👏 Congrats to the whole #TBTlab & collaborators!
aacrjournals.org/cancerres/ar...
Reposted by Peio Azcoaga
Register for Cancer Metabolism!
Join us in Bilbao to hear from top experts in the field discussing the metabolic alterations in tumours, the mechanisms through which metabolites regulate cell decisions and the metabolic interaction between the tumour and the host.
eacr.org/conference/c...
Join us in Bilbao to hear from top experts in the field discussing the metabolic alterations in tumours, the mechanisms through which metabolites regulate cell decisions and the metabolic interaction between the tumour and the host.
eacr.org/conference/c...
November 7, 2025 at 9:01 AM
Register for Cancer Metabolism!
Join us in Bilbao to hear from top experts in the field discussing the metabolic alterations in tumours, the mechanisms through which metabolites regulate cell decisions and the metabolic interaction between the tumour and the host.
eacr.org/conference/c...
Join us in Bilbao to hear from top experts in the field discussing the metabolic alterations in tumours, the mechanisms through which metabolites regulate cell decisions and the metabolic interaction between the tumour and the host.
eacr.org/conference/c...
Reposted by Peio Azcoaga
There's not long left for you to submit your abstract for our Overactivation of Oncogenic Signalling as a Potential Cancer Treatment Strategy conference!
If your research falls into any of these categories, don't miss your opportunity to be included in this conference:
eacr.org/conference/o...
If your research falls into any of these categories, don't miss your opportunity to be included in this conference:
eacr.org/conference/o...
November 5, 2025 at 9:01 AM
There's not long left for you to submit your abstract for our Overactivation of Oncogenic Signalling as a Potential Cancer Treatment Strategy conference!
If your research falls into any of these categories, don't miss your opportunity to be included in this conference:
eacr.org/conference/o...
If your research falls into any of these categories, don't miss your opportunity to be included in this conference:
eacr.org/conference/o...
Reposted by Peio Azcoaga
Looking to develop your career in cancer research? Become part of the EACR community!
Membership gives you access to a global network of dedicated scientists and exclusive funding opportunities.
See how joining can empower your research journey: eacr.org/membership
Membership gives you access to a global network of dedicated scientists and exclusive funding opportunities.
See how joining can empower your research journey: eacr.org/membership
November 3, 2025 at 9:01 AM
Looking to develop your career in cancer research? Become part of the EACR community!
Membership gives you access to a global network of dedicated scientists and exclusive funding opportunities.
See how joining can empower your research journey: eacr.org/membership
Membership gives you access to a global network of dedicated scientists and exclusive funding opportunities.
See how joining can empower your research journey: eacr.org/membership
Reposted by Peio Azcoaga
Here is my weekly selection of #anticancer #therapy and #metabolic #reprogramming! Many interesting paper today 🤩 Enjoy and feedback! 🙏 @biomednews.bsky.social biomed.news/bims-meract/...
a man is reading a book in front of a pumpkin and candle
ALT: a man is reading a book in front of a pumpkin and candle
media.tenor.com
November 2, 2025 at 4:24 PM
Here is my weekly selection of #anticancer #therapy and #metabolic #reprogramming! Many interesting paper today 🤩 Enjoy and feedback! 🙏 @biomednews.bsky.social biomed.news/bims-meract/...
Reposted by Peio Azcoaga
Good Sunday, mitolovers. Here is a wonderful selection of papers in #cancermetabolism and #mitochondrialbiology:
biomed.news/bims-camemi/...
@biomednews.bsky.social #keepreading
"Coming back to where you started is not the same as never leaving."-Terry Pratchett
biomed.news/bims-camemi/...
@biomednews.bsky.social #keepreading
"Coming back to where you started is not the same as never leaving."-Terry Pratchett
November 2, 2025 at 5:49 AM
Good Sunday, mitolovers. Here is a wonderful selection of papers in #cancermetabolism and #mitochondrialbiology:
biomed.news/bims-camemi/...
@biomednews.bsky.social #keepreading
"Coming back to where you started is not the same as never leaving."-Terry Pratchett
biomed.news/bims-camemi/...
@biomednews.bsky.social #keepreading
"Coming back to where you started is not the same as never leaving."-Terry Pratchett
Reposted by Peio Azcoaga
Accumulation of succinate suppresses de novo purine synthesis through succinylation-mediated control of the mitochondrial folate cyclehttps://
www.sciencedirect.com/science/article/abs/pii/S1097276525008196
Congratulations @bensahralab.bsky.social !!
www.sciencedirect.com/science/article/abs/pii/S1097276525008196
Congratulations @bensahralab.bsky.social !!
Accumulation of succinate suppresses de novo purine synthesis through succinylation-mediated control of the mitochondrial folate cycle
The de novo purine synthesis pathway is fundamental for nucleotide production, yet the role of mitochondrial metabolism in modulating this process rem…
www.sciencedirect.com
October 29, 2025 at 5:23 AM
Accumulation of succinate suppresses de novo purine synthesis through succinylation-mediated control of the mitochondrial folate cyclehttps://
www.sciencedirect.com/science/article/abs/pii/S1097276525008196
Congratulations @bensahralab.bsky.social !!
www.sciencedirect.com/science/article/abs/pii/S1097276525008196
Congratulations @bensahralab.bsky.social !!
Reposted by Peio Azcoaga
As part of the EACR’s #KeepResearchCurious campaign, earlier this year we hosted a panel with four expert guests to discuss the importance of curiosity-driven research in advancing medical breakthroughs.
Watch the replay: magazine.eacr.org/video-keepre...
Watch the replay: magazine.eacr.org/video-keepre...
VIDEO: #KeepResearchCurious Expert Panel Discussion on Why Basic Research Matters - The Cancer Researcher
As part of the EACR's #KeepResearchCurious campaign, EACR Scientific Officer Dr Alexandra Boitor recently hosted a panel with four prominent scientists to highlight the importance of curiosity-driven…
magazine.eacr.org
October 30, 2025 at 9:30 AM
As part of the EACR’s #KeepResearchCurious campaign, earlier this year we hosted a panel with four expert guests to discuss the importance of curiosity-driven research in advancing medical breakthroughs.
Watch the replay: magazine.eacr.org/video-keepre...
Watch the replay: magazine.eacr.org/video-keepre...
Reposted by Peio Azcoaga
📧 Are you subscribed to the EACR email list?
You'll get access to the latest news, jobs, meetings and other announcements that are of interest to cancer researchers, direct to your inbox every two weeks.
Subscribe here: us5.list-manage.com/subscribe?u=...
You'll get access to the latest news, jobs, meetings and other announcements that are of interest to cancer researchers, direct to your inbox every two weeks.
Subscribe here: us5.list-manage.com/subscribe?u=...
October 28, 2025 at 9:02 AM
📧 Are you subscribed to the EACR email list?
You'll get access to the latest news, jobs, meetings and other announcements that are of interest to cancer researchers, direct to your inbox every two weeks.
Subscribe here: us5.list-manage.com/subscribe?u=...
You'll get access to the latest news, jobs, meetings and other announcements that are of interest to cancer researchers, direct to your inbox every two weeks.
Subscribe here: us5.list-manage.com/subscribe?u=...
Reposted by Peio Azcoaga
EACR Board members and other key opinion leaders author regular EACR Viewpoint articles for publication in our affiliated journal @moloncology.bsky.social 🧠
Catch up with all the EACR Viewpoints published to date: febs.onlinelibrary.wiley.com/doi/toc/10.1...
Catch up with all the EACR Viewpoints published to date: febs.onlinelibrary.wiley.com/doi/toc/10.1...
October 27, 2025 at 3:32 PM
EACR Board members and other key opinion leaders author regular EACR Viewpoint articles for publication in our affiliated journal @moloncology.bsky.social 🧠
Catch up with all the EACR Viewpoints published to date: febs.onlinelibrary.wiley.com/doi/toc/10.1...
Catch up with all the EACR Viewpoints published to date: febs.onlinelibrary.wiley.com/doi/toc/10.1...
Reposted by Peio Azcoaga
Here a selection of last week studies on #anticancer #therapy and #metabolic #reprogramming. Big thanks @biomednews.bsky.social for presorting them.
V good studies in this issue, have a look
biomed.news/bims-meract/...
V good studies in this issue, have a look
biomed.news/bims-meract/...
a man with glasses and a beard is making a perfect choice face
ALT: a man with glasses and a beard is making a perfect choice face
media.tenor.com
October 26, 2025 at 10:27 PM
Here a selection of last week studies on #anticancer #therapy and #metabolic #reprogramming. Big thanks @biomednews.bsky.social for presorting them.
V good studies in this issue, have a look
biomed.news/bims-meract/...
V good studies in this issue, have a look
biomed.news/bims-meract/...
Reposted by Peio Azcoaga
Good Sunday, all! Here is an exciting selection of papers in #cancermetabolism and #mitochondrialbiology: biomed.news/bims-camemi/...
@biomednews.bsky.social #keepreading
"Inside us there is something that has no name, that something is what we are."-José Saramago
@biomednews.bsky.social #keepreading
"Inside us there is something that has no name, that something is what we are."-José Saramago
October 26, 2025 at 6:25 AM
Good Sunday, all! Here is an exciting selection of papers in #cancermetabolism and #mitochondrialbiology: biomed.news/bims-camemi/...
@biomednews.bsky.social #keepreading
"Inside us there is something that has no name, that something is what we are."-José Saramago
@biomednews.bsky.social #keepreading
"Inside us there is something that has no name, that something is what we are."-José Saramago
Reposted by Peio Azcoaga
A valuable way to connect with peers as an EACR member is by using our Find a Collaboration tool 🤝
For more information visit: www.eacr.org/find-a-colla...
For more information visit: www.eacr.org/find-a-colla...
October 23, 2025 at 8:02 AM
A valuable way to connect with peers as an EACR member is by using our Find a Collaboration tool 🤝
For more information visit: www.eacr.org/find-a-colla...
For more information visit: www.eacr.org/find-a-colla...
Reposted by Peio Azcoaga
People with some cancers live longer after COVID vaccination 😮
mRNA vaccines can augment immune checkpoint inhibition efficacy for patients with skin or lung cancers - by globally boosting immune responses 💉🧪⚕️
www.nature.com/articles/d41...
Grippen et al study:
www.nature.com/articles/s41...
mRNA vaccines can augment immune checkpoint inhibition efficacy for patients with skin or lung cancers - by globally boosting immune responses 💉🧪⚕️
www.nature.com/articles/d41...
Grippen et al study:
www.nature.com/articles/s41...
People with some cancers live longer after a COVID vaccine
mRNA vaccines seem to boost the effectiveness of an immune therapy for skin and lung cancer ― in an unexpected way.
www.nature.com
October 22, 2025 at 6:08 PM
People with some cancers live longer after COVID vaccination 😮
mRNA vaccines can augment immune checkpoint inhibition efficacy for patients with skin or lung cancers - by globally boosting immune responses 💉🧪⚕️
www.nature.com/articles/d41...
Grippen et al study:
www.nature.com/articles/s41...
mRNA vaccines can augment immune checkpoint inhibition efficacy for patients with skin or lung cancers - by globally boosting immune responses 💉🧪⚕️
www.nature.com/articles/d41...
Grippen et al study:
www.nature.com/articles/s41...
Reposted by Peio Azcoaga
Good Sunday, mitolovers! 🌟 Exciting news in the world of #cancermetabolism and #mitochondrialbiology! 🧬 Check out the papers from last week here: biomed.news/bims-camemi/... @biomednews.bsky.social #keepreading📚
"Knowledge is an unending adventure at the edge of uncertainty."-Jacob Bronowski
"Knowledge is an unending adventure at the edge of uncertainty."-Jacob Bronowski
October 19, 2025 at 5:35 AM
Good Sunday, mitolovers! 🌟 Exciting news in the world of #cancermetabolism and #mitochondrialbiology! 🧬 Check out the papers from last week here: biomed.news/bims-camemi/... @biomednews.bsky.social #keepreading📚
"Knowledge is an unending adventure at the edge of uncertainty."-Jacob Bronowski
"Knowledge is an unending adventure at the edge of uncertainty."-Jacob Bronowski
Reposted by Peio Azcoaga
Join us for this exciting new virtual conference to be part of the conversation about how meaningful involvement of cancer patient advocates throughout the research process drives impactful change in cancer research.
Register now from just €25: eacr.org/conference/p...
Register now from just €25: eacr.org/conference/p...
October 16, 2025 at 8:02 AM
Join us for this exciting new virtual conference to be part of the conversation about how meaningful involvement of cancer patient advocates throughout the research process drives impactful change in cancer research.
Register now from just €25: eacr.org/conference/p...
Register now from just €25: eacr.org/conference/p...
Reposted by Peio Azcoaga
We study cancer progression and metastasis. Today wearing the 🎗️ we would like to thank all collaborators, patients & their families, and funders because together we are working towards a future where cancer is less life threatening than today! @fwovlaanderen.bsky.social #STK #KOTK @wcrf.org
October 16, 2025 at 3:28 PM
We study cancer progression and metastasis. Today wearing the 🎗️ we would like to thank all collaborators, patients & their families, and funders because together we are working towards a future where cancer is less life threatening than today! @fwovlaanderen.bsky.social #STK #KOTK @wcrf.org