Pacific Optica
@pacificoptica.bsky.social
Optics for multiphoton imaging, laser scanning, and more. Based in Santa Barbara, California. pacificoptica.com
Happy Halloween!
pacificoptica.com/cousa/
pacificoptica.com/cousa/
October 31, 2025 at 1:34 AM
Happy Halloween!
pacificoptica.com/cousa/
pacificoptica.com/cousa/
Check out some sweet Ventana Wide + Cousa imaging.
pacificoptica.com/ventana/
Live raw data over a 3.2 mm wide field-of-view with 16,000 lines/s scanning and submicron resolution. Demo now at @omibs-mbl.bsky.social
Thx @ewadorotaz.bsky.social @mbfbioscience.bsky.social @crisrodtsou.bsky.social !
pacificoptica.com/ventana/
Live raw data over a 3.2 mm wide field-of-view with 16,000 lines/s scanning and submicron resolution. Demo now at @omibs-mbl.bsky.social
Thx @ewadorotaz.bsky.social @mbfbioscience.bsky.social @crisrodtsou.bsky.social !
August 20, 2025 at 1:46 AM
Check out some sweet Ventana Wide + Cousa imaging.
pacificoptica.com/ventana/
Live raw data over a 3.2 mm wide field-of-view with 16,000 lines/s scanning and submicron resolution. Demo now at @omibs-mbl.bsky.social
Thx @ewadorotaz.bsky.social @mbfbioscience.bsky.social @crisrodtsou.bsky.social !
pacificoptica.com/ventana/
Live raw data over a 3.2 mm wide field-of-view with 16,000 lines/s scanning and submicron resolution. Demo now at @omibs-mbl.bsky.social
Thx @ewadorotaz.bsky.social @mbfbioscience.bsky.social @crisrodtsou.bsky.social !
Reposted by Pacific Optica
Scientists explore, measure, gather evidence, figure things out, and share openly. Their work benefits us all.
Demo imaging at MBL/Woods Hole and CSHL this summer. Explore further. pacificoptica.com
Demo imaging at MBL/Woods Hole and CSHL this summer. Explore further. pacificoptica.com
August 14, 2025 at 12:32 AM
Scientists explore, measure, gather evidence, figure things out, and share openly. Their work benefits us all.
Demo imaging at MBL/Woods Hole and CSHL this summer. Explore further. pacificoptica.com
Demo imaging at MBL/Woods Hole and CSHL this summer. Explore further. pacificoptica.com
Put whatever objective you want on the Ventana Wide. It will give you the largest field of view with high speed scanning: eg, 3.2mm x 3.2mm with a 10x. Fast, flexible 2p imaging.
Che-Hang Yu is helping MBL courses with this Ventana Wide system pacificoptica.com/ventana/
Che-Hang Yu is helping MBL courses with this Ventana Wide system pacificoptica.com/ventana/
August 2, 2025 at 7:40 AM
Put whatever objective you want on the Ventana Wide. It will give you the largest field of view with high speed scanning: eg, 3.2mm x 3.2mm with a 10x. Fast, flexible 2p imaging.
Che-Hang Yu is helping MBL courses with this Ventana Wide system pacificoptica.com/ventana/
Che-Hang Yu is helping MBL courses with this Ventana Wide system pacificoptica.com/ventana/
Just landed in Woods Hole for summer courses: a Full Ventana Wide system. pacificoptica.com/ventana/ with a Cousa pacificoptica.com/cousa/
www.mbl.edu/education/ad...
www.mbl.edu/education/ad...
Thanks, Coherent! Thanks, MBF! Thanks to course leadership and MBL staff!
www.mbl.edu/education/ad...
www.mbl.edu/education/ad...
Thanks, Coherent! Thanks, MBF! Thanks to course leadership and MBL staff!
August 2, 2025 at 4:53 AM
Just landed in Woods Hole for summer courses: a Full Ventana Wide system. pacificoptica.com/ventana/ with a Cousa pacificoptica.com/cousa/
www.mbl.edu/education/ad...
www.mbl.edu/education/ad...
Thanks, Coherent! Thanks, MBF! Thanks to course leadership and MBL staff!
www.mbl.edu/education/ad...
www.mbl.edu/education/ad...
Thanks, Coherent! Thanks, MBF! Thanks to course leadership and MBL staff!
Widespread cortical representations of innate behaviors in the mouse. www.biorxiv.org/content/10.1... Using the Diesel2p pacificoptica.com/diesel2p/, they found that "more directed and unilateral grooming movements had greater cortical associated responses than more
stereotyped bilateral movements"
stereotyped bilateral movements"
July 30, 2025 at 6:21 AM
Widespread cortical representations of innate behaviors in the mouse. www.biorxiv.org/content/10.1... Using the Diesel2p pacificoptica.com/diesel2p/, they found that "more directed and unilateral grooming movements had greater cortical associated responses than more
stereotyped bilateral movements"
stereotyped bilateral movements"
We will start gathering at about 3:00.
吉祥寺 日曜日。2-photon, optics, 生ビルと TexMex 食べ物。 maps.app.goo.gl/xoRrGNX7xvK1... ふるってご参加ください。
maps.app.goo.gl
July 19, 2025 at 1:03 AM
We will start gathering at about 3:00.
吉祥寺 日曜日。2-photon, optics, 生ビルと TexMex 食べ物。 maps.app.goo.gl/xoRrGNX7xvK1... ふるってご参加ください。
maps.app.goo.gl
July 18, 2025 at 11:05 AM
吉祥寺 日曜日。2-photon, optics, 生ビルと TexMex 食べ物。 maps.app.goo.gl/xoRrGNX7xvK1... ふるってご参加ください。
No more stitching artifacts. Just image the whole field-of-view, at high resolution, in one pass. The Ventana systems give submicron resolution over huge fields-of-view almost 10 square mm. At high speed. Cover a 3.2 mm x 3.2 mm area in 4k resolution in 0.26 s. pacificoptica.com/ventana/
July 14, 2025 at 1:16 AM
No more stitching artifacts. Just image the whole field-of-view, at high resolution, in one pass. The Ventana systems give submicron resolution over huge fields-of-view almost 10 square mm. At high speed. Cover a 3.2 mm x 3.2 mm area in 4k resolution in 0.26 s. pacificoptica.com/ventana/
Explore further. pacificoptica.com/diesel2p/
July 13, 2025 at 9:04 AM
Explore further. pacificoptica.com/diesel2p/
Cool!! This is an exciting new Neuro AI #NeurIPS competition.
By the way, the large scale 2p data for this NeurIPS competition was taken with a Diesel2p system. pacificoptica.com/diesel2p/
By the way, the large scale 2p data for this NeurIPS competition was taken with a Diesel2p system. pacificoptica.com/diesel2p/
July 12, 2025 at 3:39 AM
Cool!! This is an exciting new Neuro AI #NeurIPS competition.
By the way, the large scale 2p data for this NeurIPS competition was taken with a Diesel2p system. pacificoptica.com/diesel2p/
By the way, the large scale 2p data for this NeurIPS competition was taken with a Diesel2p system. pacificoptica.com/diesel2p/
Reposted by Pacific Optica
🌌 Curious how visionary engineering shaped one of humanity’s greatest scientific instruments? Discover the architectural origins of the JWST in this in-depth #SPIE_JATIS article: www.spiedigitallibra...
July 8, 2025 at 11:01 PM
🌌 Curious how visionary engineering shaped one of humanity’s greatest scientific instruments? Discover the architectural origins of the JWST in this in-depth #SPIE_JATIS article: www.spiedigitallibra...
Reposted by Pacific Optica
ALERT: New journal club style!
S. L. Smith listens to and provides commentary on an AI-generated fake podcast on their new preprint.
Hilarious in parts, and fun and chill.
Everyone: Please do this for your papers too!
m.youtube.com/watch?v=qO1n...
S. L. Smith listens to and provides commentary on an AI-generated fake podcast on their new preprint.
Hilarious in parts, and fun and chill.
Everyone: Please do this for your papers too!
m.youtube.com/watch?v=qO1n...
Non-inertial scan angle multiplier - AI-generated podcast with actual human commentary
YouTube video by Spencer LaVere Smith
m.youtube.com
June 17, 2025 at 2:32 PM
ALERT: New journal club style!
S. L. Smith listens to and provides commentary on an AI-generated fake podcast on their new preprint.
Hilarious in parts, and fun and chill.
Everyone: Please do this for your papers too!
m.youtube.com/watch?v=qO1n...
S. L. Smith listens to and provides commentary on an AI-generated fake podcast on their new preprint.
Hilarious in parts, and fun and chill.
Everyone: Please do this for your papers too!
m.youtube.com/watch?v=qO1n...
Reposted by Pacific Optica
So excited to hang the ‘Acknowlegement Guidelines’ poster up in Chapel Hill! Grateful to be part of the community working towards equitable recognition for imaging scientists!!
Read more and download the poster (in 10 languages!): lnkd.in/eSQRugJX
#CreditWhereItsDue
#AcknowledgementGuidelines
Read more and download the poster (in 10 languages!): lnkd.in/eSQRugJX
#CreditWhereItsDue
#AcknowledgementGuidelines
June 24, 2025 at 2:19 PM
So excited to hang the ‘Acknowlegement Guidelines’ poster up in Chapel Hill! Grateful to be part of the community working towards equitable recognition for imaging scientists!!
Read more and download the poster (in 10 languages!): lnkd.in/eSQRugJX
#CreditWhereItsDue
#AcknowledgementGuidelines
Read more and download the poster (in 10 languages!): lnkd.in/eSQRugJX
#CreditWhereItsDue
#AcknowledgementGuidelines
Now published in Plos Biology journals.plos.org/plosbiology/...
June 24, 2025 at 2:17 PM
Now published in Plos Biology journals.plos.org/plosbiology/...
Animals sense in complex environments, and neuronal responses to olfactory/scent stimuli can be shaped by recent history going back ~ 30 s. Here, Subramanian, Storace, et al. used the Cousa objective pacificoptica.com/cousa/ to neural activity in vivo. doi.org/10.1093/chem... #microscopymonday
June 23, 2025 at 5:57 PM
Animals sense in complex environments, and neuronal responses to olfactory/scent stimuli can be shaped by recent history going back ~ 30 s. Here, Subramanian, Storace, et al. used the Cousa objective pacificoptica.com/cousa/ to neural activity in vivo. doi.org/10.1093/chem... #microscopymonday
Multinucleated giant cells (MNGCs) emerge as ovaries age, and are hard to study. Here, Converse, Pritchard, Duncan et al. used 2p imaging with the Cousa objective pacificoptica.com/cousa/ in their comprehensive study of age-associated MNGCs. #microscopymonday www.biorxiv.org/content/10.1...
June 23, 2025 at 5:43 PM
Multinucleated giant cells (MNGCs) emerge as ovaries age, and are hard to study. Here, Converse, Pritchard, Duncan et al. used 2p imaging with the Cousa objective pacificoptica.com/cousa/ in their comprehensive study of age-associated MNGCs. #microscopymonday www.biorxiv.org/content/10.1...
This system has tons of fascinating tech— optics, detectors, software— so many scientists and engineers collaborated on this international project, enjoy the fruits of their talents!
The image offers a stunning variety of objects — from bright stars ranging from blue to red in color, to nearby blue spiral galaxies, to distant red galaxy groups — demonstrating the broad range of science made possible by Rubin data ✨🔭🧪
June 23, 2025 at 3:56 PM
This system has tons of fascinating tech— optics, detectors, software— so many scientists and engineers collaborated on this international project, enjoy the fruits of their talents!
Reposted by Pacific Optica
Fantastic work (as always) from Che-Hang Yu and colleagues in Spencer LaVere Smith's lab. Very neat method to increase scan speed and/or FOV in 2p microscopy. Commercially available from @pacificoptica.bsky.social. I'd love to build this for a client at some point! www.biorxiv.org/content/10.1...
June 19, 2025 at 11:47 AM
Fantastic work (as always) from Che-Hang Yu and colleagues in Spencer LaVere Smith's lab. Very neat method to increase scan speed and/or FOV in 2p microscopy. Commercially available from @pacificoptica.bsky.social. I'd love to build this for a client at some point! www.biorxiv.org/content/10.1...
Reposted by Pacific Optica
🚨THIS IS NOT A DRILL🚨We are 6 days away from the world's First Look at images from Rubin! #RubinFirstLook 🔭🧪
NSF–DOE Rubin Observatory will take a new 3200-megapixel image every ~40s, yielding ~20 terabytes of data every night! The deluge of data is about to begin 🌊
NSF–DOE Rubin Observatory will take a new 3200-megapixel image every ~40s, yielding ~20 terabytes of data every night! The deluge of data is about to begin 🌊
June 17, 2025 at 4:22 PM
🚨THIS IS NOT A DRILL🚨We are 6 days away from the world's First Look at images from Rubin! #RubinFirstLook 🔭🧪
NSF–DOE Rubin Observatory will take a new 3200-megapixel image every ~40s, yielding ~20 terabytes of data every night! The deluge of data is about to begin 🌊
NSF–DOE Rubin Observatory will take a new 3200-megapixel image every ~40s, yielding ~20 terabytes of data every night! The deluge of data is about to begin 🌊
ALERT: New journal club style!
S. L. Smith listens to and provides commentary on an AI-generated fake podcast on their new preprint.
Hilarious in parts, and fun and chill.
Everyone: Please do this for your papers too!
m.youtube.com/watch?v=qO1n...
S. L. Smith listens to and provides commentary on an AI-generated fake podcast on their new preprint.
Hilarious in parts, and fun and chill.
Everyone: Please do this for your papers too!
m.youtube.com/watch?v=qO1n...
Non-inertial scan angle multiplier - AI-generated podcast with actual human commentary
YouTube video by Spencer LaVere Smith
m.youtube.com
June 17, 2025 at 2:32 PM
ALERT: New journal club style!
S. L. Smith listens to and provides commentary on an AI-generated fake podcast on their new preprint.
Hilarious in parts, and fun and chill.
Everyone: Please do this for your papers too!
m.youtube.com/watch?v=qO1n...
S. L. Smith listens to and provides commentary on an AI-generated fake podcast on their new preprint.
Hilarious in parts, and fun and chill.
Everyone: Please do this for your papers too!
m.youtube.com/watch?v=qO1n...
Riddle: When is an "optical invariant" is not so invariant? How can you get a larger field-of-view for free? No change in resolution or scan speed. No more stitching needed! For #MicroscopyMonday here's a new preprint to check out. 1/9
June 16, 2025 at 5:57 PM
Riddle: When is an "optical invariant" is not so invariant? How can you get a larger field-of-view for free? No change in resolution or scan speed. No more stitching needed! For #MicroscopyMonday here's a new preprint to check out. 1/9
Scientists at work.
This is a #ucsantabarbara collab with www.mbfbioscience.com Diesel2p pacificoptica.com/diesel2p/
This is a #ucsantabarbara collab with www.mbfbioscience.com Diesel2p pacificoptica.com/diesel2p/
May 29, 2025 at 6:25 AM
Scientists at work.
This is a #ucsantabarbara collab with www.mbfbioscience.com Diesel2p pacificoptica.com/diesel2p/
This is a #ucsantabarbara collab with www.mbfbioscience.com Diesel2p pacificoptica.com/diesel2p/
Upgrade your 2p to 4k.
We used to have to trade off resolution to get a larger field-of-view. Now, with Ventana, you don’t have to.
Keep your resolution. Keep your frame rate. And get 4x the field-of-view. pacificoptica.com/ventana/
We used to have to trade off resolution to get a larger field-of-view. Now, with Ventana, you don’t have to.
Keep your resolution. Keep your frame rate. And get 4x the field-of-view. pacificoptica.com/ventana/
Ventana - Pacific Optica
pacificoptica.com
April 26, 2025 at 11:07 PM
Upgrade your 2p to 4k.
We used to have to trade off resolution to get a larger field-of-view. Now, with Ventana, you don’t have to.
Keep your resolution. Keep your frame rate. And get 4x the field-of-view. pacificoptica.com/ventana/
We used to have to trade off resolution to get a larger field-of-view. Now, with Ventana, you don’t have to.
Keep your resolution. Keep your frame rate. And get 4x the field-of-view. pacificoptica.com/ventana/