Winona Oliveros
oliveroswinona.bsky.social
Winona Oliveros
@oliveroswinona.bsky.social
Microbiologist — Bioinformatics — PhD in Biomedicine/Bioinformatics (BSC) — Postdoc @ Lappalainen Lab
Reposted by Winona Oliveros
1/ Everything that could go wrong in paper publishing… did.
A story of patience, absurdity, and persistence 🌀 <1min

From Alfonso Valencia’s lab and a very stubborn PhD student (me).
September 2, 2025 at 6:37 PM
Reposted by Winona Oliveros
🚨 We are hiring a Postdoc @crg.eu! 🧬

Within the EU-funded #PrecisionTox project. We are developing computational methods to predict toxicity by integrating RNA-seq data from humans and model species 🪱🪰🐸🐠. The project will help replace animal testing.

🔗 Apply now: recruitment.crg.eu/content/jobs...
Post-Doctoral Researcher for Precision Tox | CRG Online Recruitment Portal
The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by high-end and innovative technologies.
recruitment.crg.eu
July 28, 2025 at 10:09 AM
Reposted by Winona Oliveros
🚬The molecular impact of cigarette smoking resembles aging across tissues

⭕This is the 1st comprehensive, multi-tissue analysis to show that smoking doesn’t just harm specific organs like the lungs 🫁

📄By BSC & Universidade do Porto researchers, published in Genome Medicine: bsc.es/Zt2
June 5, 2025 at 8:11 AM
🧬 I’m thrilled to share our latest publication in Genome Medicine, led by the brilliant @ramirezjmiguel.bsky.social :

“The molecular impact of cigarette smoking resembles aging across tissues”

👉 genomemedicine.biomedcentral.com/articles/10....
The molecular impact of cigarette smoking resembles aging across tissues - Genome Medicine
Background Tobacco smoke is the main cause of preventable mortality worldwide. Smoking increases the risk of developing many diseases and has been proposed as an aging accelerator. Yet, the molecular ...
genomemedicine.biomedcentral.com
June 4, 2025 at 8:43 AM
Reposted by Winona Oliveros
so well deserved! congratulations!!! @pclavell.bsky.social @melelab.bsky.social 🚀⭐️💫
ESHG2025# Early Career awards:
For outstanding science presented at the conference

- Allison Newman, Exeter, UK
- Hristiana Lyubenova, Berlin, Germany
- Robin J. Hofmeister, Lausanne, Switzerland
- Pau Clavell-Revelles, Barcelona, Spain
May 27, 2025 at 7:14 PM
Reposted by Winona Oliveros
It's been an absolute pleasure to present my work on long-read transcriptomics in front of such a big audience at the European Conference of Human Genetics @eshg.bsky.social in Milano.
The feedback and the discussion were extremely interesting and useful!
May 30, 2025 at 10:55 AM
Reposted by Winona Oliveros
I am so happy to learn that I won the Early Career Award for an outstanding presentation at the ESHG!!
Thanks to @melelab.bsky.social, @guigolab.bsky.social and to my awesome colleagues that also attended the conference for their support @rubenchazarra.bsky.social @ramirezjmiguel.bsky.social
May 30, 2025 at 10:57 AM
Reposted by Winona Oliveros
Our new contribution to the quest to find causal GWAS genes! Sam Ghatan from my lab at @nygenome.org led a systematic comparison of eQTLs and CRISPRi+scRNA-seq screens. TL;DR: they provide highly complementary insights, with ortogonal pros and cons. 🧵👇
www.biorxiv.org/content/10.1...
May 6, 2025 at 5:01 PM
Excited to share our new preprint: The impact of sex, age, and genetic ancestry on DNA methylation across tissues. Briefly, we explored how sex, age, and genetic ancestry shape DNA methylation across tissues and individuals. Want to know a bit more? Follow this “bluetorial”!
doi.org/10.1101/2025...
The impact of sex, age, and genetic ancestry on DNA methylation across tissues
Background: Understanding the consequences of individual DNA methylation variation is crucial for the study of human biology and disease. However, the collective impact of demographic traits on DNA me...
www.biorxiv.org
May 5, 2025 at 3:44 PM
Reposted by Winona Oliveros
It's a beautiful spring day in Barcelona. Sunshine welcoming all our guests for the first day of the CRG's annual symposium! This year's theme is all about the mechanisms of gene expression.
April 24, 2025 at 8:56 AM
Reposted by Winona Oliveros
👶🏼 Many #vaccines are not effective in newborns. So how do we protect them from infectious disease?

🤰🏽 By vaccination in #pregnancy!

Here we review…

💉 Established campaigns vs whooping cough, flu, COVID

💡 New approaches to RSV, GBS

🌈 Future challenges, opportunities

#ReproSky #ImmunoSky #IDSky
Vaccination in pregnancy to protect the newborn - Nature Reviews Immunology
In this Review, Male and Jones provide an overview of the current vaccines that are offered during pregnancy and to newborns, explaining the rationale behind the different vaccination programmes and t...
www.nature.com
April 24, 2025 at 6:21 AM
Reposted by Winona Oliveros
New evidence @nejm.org today that age-related clonal hematopoiesis (CHIP) has a driver role in evolution of solid cancers
www.nejm.org/doi/full/10....
www.nejm.org/doi/full/10....
Clonal Hematopoiesis as a Driver of Solid Tumors | NEJM
Clonal hematopoiesis is the expansion of a genetically related population of hematopoietic stem and progenitor cells that disproportionately contribute to blood-cell production.1 Clonal hematopoies...
www.nejm.org
April 23, 2025 at 10:22 PM
Reposted by Winona Oliveros
This is what scientific leadership and courage looks like:

www.harvard.edu
Harvard University
Harvard University is devoted to excellence in teaching, learning, and research, and to developing leaders who make a difference globally.
www.harvard.edu
April 15, 2025 at 3:14 AM
Reposted by Winona Oliveros
We called out Harvard in the past for inaction. So now we are happy to speak out with praise.

This is a major step forward.

It’s not just a lack of capitulation. It’s an aggressive effort leaning into public comms — exactly what is needed. Bravo to Harvard 👏
Harvard redid its whole homepage to push back against the administration’s demands. I mean, this is just a website but I think it’s kind of a great PR move: www.harvard.edu
Harvard University
Harvard University is devoted to excellence in teaching, learning, and research, and to developing leaders who make a difference globally.
www.harvard.edu
April 14, 2025 at 10:50 PM
Reposted by Winona Oliveros
🎆 Congratulations to @elisamasber.bsky.social, from the Aerosols, Dust and Climate group, on the successful defence of her #PhD thesis!

🙌We wish you all the best, Elisa!

#BSCTalent
April 14, 2025 at 7:57 AM
Reposted by Winona Oliveros
Congratulations @oliveroswinona.bsky.social!!! A humongous amount of great work!! So proud and happy for you, even though you set the bar very high for the rest of us in the @melelab.bsky.social
Yesterday I defended my PhD thesis at the UB after nearly 5 years of work at the BSC @melelab.bsky.social. I couldn’t be happier! This wouldn’t have been possible without my amazing friends and fellow PhD students. 💘🎉
April 8, 2025 at 10:38 AM
Yesterday I defended my PhD thesis at the UB after nearly 5 years of work at the BSC @melelab.bsky.social. I couldn’t be happier! This wouldn’t have been possible without my amazing friends and fellow PhD students. 💘🎉
April 8, 2025 at 10:27 AM
Reposted by Winona Oliveros
Deadline to register for the CRG's annual symposium is fast approaching. Sign up before Friday 11 April to attend!

www.crg.eu/en/event/202...
April 3, 2025 at 6:17 AM
Reposted by Winona Oliveros
Nuestro director Luis Serrano, hoy en la portada de @elpais.com: "España debería hacer un esfuerzo presupuestario para atraer este talento. La última vez que se planteó algo así fue tras la caída del Muro de Berlín. Solo falta voluntad política".
Hablan los científicos que quieren emigrar a España por Trump: “Tengo miedo al fascismo”
Centros punteros de Barcelona y Madrid reciben decenas de solicitudes de investigadores en Estados Unidos
elpais.com
March 27, 2025 at 9:06 AM
Reposted by Winona Oliveros
🟢Overall, our work suggests that to overcome gene annotation ancestry biases we require:

🥇long-read sequencing of transcriptomes from diverse human populations

🥈the development of transcript discovery tools for the pangenome @humanpangenome.bsky.social to bypass reference biases

Preprint ⬇️⬇️⬇️

13
Long-read transcriptomics of a diverse human cohort reveals widespread ancestry bias in gene annotation
Accurate gene annotations are fundamental for interpreting genetic variation, cellular function, and disease mechanisms. However, current human gene annotations are largely derived from transcriptomic...
www.biorxiv.org
March 20, 2025 at 1:20 PM
Reposted by Winona Oliveros
Do you work in 💫human genetics💫?
Have you ever worried about what’s inside your gene annotation GTF⁉️

WELL, YOU SHOULD! 😱
Especially when studying a genetically diverse 🌍 cohort!

🔴We discover that gene annotations are European-biased 👉 impacting downstream analyses!

Don't miss this thread🧵⬇️
1/13
Long-read transcriptomics of a diverse human cohort reveals widespread ancestry bias in gene annotation
Accurate gene annotations are fundamental for interpreting genetic variation, cellular function, and disease mechanisms. However, current human gene annotations are largely derived from transcriptomic...
www.biorxiv.org
March 20, 2025 at 1:20 PM
Reposted by Winona Oliveros
There are days in life that shake you.

I’m shattered 💔 to share that I just found out that the US Government terminated my 2024 NIH Director’s Early Independence Award (~$2 million), threatening my long-promised assistant professor job at Columbia University
& academic career... 1/🧵
March 18, 2025 at 11:27 PM
I am SO EXCITED about this! An incredible amount of work from two brilliant people. I believe a bluetorial is on the way, stay tuned! 💜 @fairlie.bsky.social @pclavell.bsky.social @melelab.bsky.social @guigolab.bsky.social
Long-read transcriptomics of a diverse human cohort reveals widespread ancestry bias in gene annotation https://www.biorxiv.org/content/10.1101/2025.03.14.643250v1
March 18, 2025 at 9:40 AM