Nikhil Bharambe
@nikydna.bsky.social
Reposted by Nikhil Bharambe
We are excited to share our latest work on GLIC published in @pnas.org, where we developed a #cryoEM data processing strategy that allowed us to isolate and reconstruct multiple asymmetric states, revealing detailed insights into the channel’s activation mechanism. tinyurl.com/mwtb4rpj
Asymmetric gating of a homopentameric ion channel GLIC revealed by cryo-EM | PNAS
Pentameric ligand-gated ion channels (pLGICs) are vital neurotransmitter receptors
that are key therapeutic targets for neurological disorders. Alt...
tinyurl.com
October 24, 2025 at 5:32 AM
We are excited to share our latest work on GLIC published in @pnas.org, where we developed a #cryoEM data processing strategy that allowed us to isolate and reconstruct multiple asymmetric states, revealing detailed insights into the channel’s activation mechanism. tinyurl.com/mwtb4rpj
We're thrilled to publish our latest research on the GLIC ion channel in PNAS!
We developed a powerful new #cryoEM data processing strategy that resolves asymmetry.
📄 Read the full paper: tinyurl.com/mustun6t 🛠️ Scripts: tinyurl.com/2n3yk29r
Stay tuned for a full tutorial soon!
#PNAS #RELION
We developed a powerful new #cryoEM data processing strategy that resolves asymmetry.
📄 Read the full paper: tinyurl.com/mustun6t 🛠️ Scripts: tinyurl.com/2n3yk29r
Stay tuned for a full tutorial soon!
#PNAS #RELION
October 24, 2025 at 8:28 AM
We're thrilled to publish our latest research on the GLIC ion channel in PNAS!
We developed a powerful new #cryoEM data processing strategy that resolves asymmetry.
📄 Read the full paper: tinyurl.com/mustun6t 🛠️ Scripts: tinyurl.com/2n3yk29r
Stay tuned for a full tutorial soon!
#PNAS #RELION
We developed a powerful new #cryoEM data processing strategy that resolves asymmetry.
📄 Read the full paper: tinyurl.com/mustun6t 🛠️ Scripts: tinyurl.com/2n3yk29r
Stay tuned for a full tutorial soon!
#PNAS #RELION
Reposted by Nikhil Bharambe
Pleasure to be part of this work www.pnas.org/doi/10.1073/... with Sandip Basak at NTU where we show asymmetric gating in GLIC!
Asymmetric gating of a homopentameric ion channel GLIC revealed by cryo-EM | PNAS
Pentameric ligand-gated ion channels (pLGICs) are vital neurotransmitter receptors
that are key therapeutic targets for neurological disorders. Alt...
www.pnas.org
October 23, 2025 at 4:24 PM
Pleasure to be part of this work www.pnas.org/doi/10.1073/... with Sandip Basak at NTU where we show asymmetric gating in GLIC!