Nico Pedroncelli
@nicopedroncelli.bsky.social
phd student @ucla bioengineering
currently puzzling over how cells sense and generate force // previously built CAR-Ts @a2bio
currently puzzling over how cells sense and generate force // previously built CAR-Ts @a2bio
Reposted by Nico Pedroncelli
Pleased to share our review on “Synthetic Mechanotransduction” — now live at Nature Reviews Bioengineering.
May the force be with you!
www.nature.com/articles/s44...
May the force be with you!
www.nature.com/articles/s44...
Synthetic mechanotransduction - Nature Reviews Bioengineering
Cells convert mechanical forces into biochemical signals through mechanotransduction, a process which can now be synthetically engineered. In this Review, we examine engineered artificial mechanotrans...
www.nature.com
October 14, 2025 at 5:03 PM
Pleased to share our review on “Synthetic Mechanotransduction” — now live at Nature Reviews Bioengineering.
May the force be with you!
www.nature.com/articles/s44...
May the force be with you!
www.nature.com/articles/s44...
Reposted by Nico Pedroncelli
I'm thrilled to finally share my PhD work on understanding how Ca2+ signals regulate the protruding front of the cell. It’s been an incredible journey working alongside all the collaborators.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
A TRPV4–dependent calcium signaling axis governs lamellipodial actin architecture to promote cell migration
Cell migration is crucial for development and tissue homeostasis, while its dysregulation leads to severe pathologies. Cell migration is driven by the extension of actin–based lamellipodia protrusions...
www.biorxiv.org
March 30, 2025 at 12:44 PM
I'm thrilled to finally share my PhD work on understanding how Ca2+ signals regulate the protruding front of the cell. It’s been an incredible journey working alongside all the collaborators.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Nico Pedroncelli
The data is the data, so don’t do an experiment unless you’re willing to accept evidence that goes against your hypothesis.
January 24, 2025 at 4:25 AM
The data is the data, so don’t do an experiment unless you’re willing to accept evidence that goes against your hypothesis.