Rollenske lab
mucimmunolbonn.bsky.social
Rollenske lab
@mucimmunolbonn.bsky.social
Lab account of the Mucosal Immunology group at the University Hospital Bonn/University of Bonn

B cells / antibodies / microbiota / mucosal immunology

https://www.immei.de/research/tim-rollenske-laboratory
We are very happy about the first publication from the Rollenske lab! Remember the last time you wanted to efficiently produce and purify recombinant dimeric mouse IgA, but you didn't know how? Here you can finally find the answer: onlinelibrary.wiley.com/doi/10.1002/...
Efficient Expression and Purification of Recombinant Mouse Dimeric IgA
Immunoglobulin (Ig) A is the main antibody isotype found on mucosal surfaces in mammals, where it is predominantly present as a dimer. Here we provide an easy, scalable, efficient, and broadly applic...
onlinelibrary.wiley.com
September 22, 2025 at 3:54 PM
We are IgA enthusiasts, but sometimes we are unfaithful: Together with our colleagues, we have updated the "IgG cloning and production from single B cells"-pipeline incl. the game-changing gene synthesis, DNA assembly and small-scale transfection steps. pubmed.ncbi.nlm.nih.gov/39424722/
Expression Cloning of Antibodies from Single Human B Cells - PubMed
The majority of lymphomas originate from B cells at the germinal center stage. Preferential selection of B-cell clones by a limited set of antigens has been suggested to drive lymphoma development. Wh...
pubmed.ncbi.nlm.nih.gov
April 10, 2025 at 3:33 AM
Mucosal stargazing! It was a pleasure to write a Preview for the new Cell Host & Microbe publication of Bana Jabri's team on how IgA can control intestinal virus populations. @cp-cellhostmicrobe.bsky.social

Preview: authors.elsevier.com/a/1kvDC6t8JE...

Paper: www.cell.com/cell-host-mi...
authors.elsevier.com
April 9, 2025 at 3:32 PM