Mort Lab
@mortlab.bsky.social
Melanocyte development and tissue homeostasis.
New in Science Advances: we link Holstein white spotting to regulatory variants in KIT and MITF, validated in ‘Holsteinized’ mice - a neat case of structural + epistatic genetics shaping coat colour. A big thanks to the Littlejohn and Yamanaka groups!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Structural and epistatic regulatory variants cause hallmark white spotting in cattle
A genetic exploration of how the Holstein got its spots.
www.science.org
November 19, 2025 at 9:37 AM
New in Science Advances: we link Holstein white spotting to regulatory variants in KIT and MITF, validated in ‘Holsteinized’ mice - a neat case of structural + epistatic genetics shaping coat colour. A big thanks to the Littlejohn and Yamanaka groups!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...