MILO Lab
@milolab.bsky.social
✨ Early holiday vibes from the microscope! ✨
Live calcium imaging of glioblastoma cells at full confluence — bursting with spontaneous activity and glowing with waves of intracellular signaling. You can even spot a few cells dividing amidst the flicker.
#CalciumImaging #Glioblastoma
Live calcium imaging of glioblastoma cells at full confluence — bursting with spontaneous activity and glowing with waves of intracellular signaling. You can even spot a few cells dividing amidst the flicker.
#CalciumImaging #Glioblastoma
November 10, 2025 at 5:13 PM
✨ Early holiday vibes from the microscope! ✨
Live calcium imaging of glioblastoma cells at full confluence — bursting with spontaneous activity and glowing with waves of intracellular signaling. You can even spot a few cells dividing amidst the flicker.
#CalciumImaging #Glioblastoma
Live calcium imaging of glioblastoma cells at full confluence — bursting with spontaneous activity and glowing with waves of intracellular signaling. You can even spot a few cells dividing amidst the flicker.
#CalciumImaging #Glioblastoma
Just wrapped up an incredible few days in Prague for the @eanoassociation.bsky.social meeting! Truly inspiring sessions, great discussions, and exciting new collaborations. The MILO Lab shined with engaging talks and eye-catching posters! Ready to keep pushing the boundaries of science together!
October 20, 2025 at 4:41 PM
Just wrapped up an incredible few days in Prague for the @eanoassociation.bsky.social meeting! Truly inspiring sessions, great discussions, and exciting new collaborations. The MILO Lab shined with engaging talks and eye-catching posters! Ready to keep pushing the boundaries of science together!
Reposted by MILO Lab
Oliver Schnell untersucht Hirntumore in ihrer Entstehung. Mit seinen Erkenntnissen möchte der Direktor der neurochirurgischen Klinik des Uniklinikums Operationen besser und sicherer machen.
FAU-Präsdient @hornegger.bsky.social war zu Besuch: www.fau.de/2025/09/news...
FAU-Präsdient @hornegger.bsky.social war zu Besuch: www.fau.de/2025/09/news...
A cup with the President - Episode 33: Prof. Dr. Oliver Schnell
FAU-Präsident Prof. Dr. Joachim Hornegger besucht in jedem Semester Professorinnen und Professoren in ihren Instituten. Dort möchte er mit ihnen ins Gespräch über ihre Forschung kommen…
www.fau.de
September 16, 2025 at 6:44 AM
Oliver Schnell untersucht Hirntumore in ihrer Entstehung. Mit seinen Erkenntnissen möchte der Direktor der neurochirurgischen Klinik des Uniklinikums Operationen besser und sicherer machen.
FAU-Präsdient @hornegger.bsky.social war zu Besuch: www.fau.de/2025/09/news...
FAU-Präsdient @hornegger.bsky.social war zu Besuch: www.fau.de/2025/09/news...
Reposted by MILO Lab
New preprint on longitudinal treatment response signatures in IDH-mutant glioma from the GLASS Consortium www.biorxiv.org/content/10.1...
Tumor-initiating genetics and therapy drive divergent molecular evolution in IDH-mutant gliomas
Astrocytomas and oligodendrogliomas are slow-growing and treatment-sensitive IDH-mutant gliomas diagnosed at ages 30-50. Local tumor regrowth and treatment resistance is inevitable resulting in 3-10 y...
www.biorxiv.org
July 16, 2025 at 6:36 PM
New preprint on longitudinal treatment response signatures in IDH-mutant glioma from the GLASS Consortium www.biorxiv.org/content/10.1...
Reposted by MILO Lab
Happy to share a short "tools of the trade" piece on our NeuroPathology Spatial Transcriptomic Analysis (NePSTA) tool. Now available @natrevcancer.nature.com www.nature.com/articles/s41...
July 5, 2025 at 9:49 AM
Happy to share a short "tools of the trade" piece on our NeuroPathology Spatial Transcriptomic Analysis (NePSTA) tool. Now available @natrevcancer.nature.com www.nature.com/articles/s41...
Reposted by MILO Lab
🧠 June 8 is #WorldBrainTumorDay — raising awareness & understanding of brain tumors.
EANO supports progress in #NeuroOncology through research, education & collaboration.
🔗 Learn more: www.eano.eu
#btsm #BrainTumor #Oncology
EANO supports progress in #NeuroOncology through research, education & collaboration.
🔗 Learn more: www.eano.eu
#btsm #BrainTumor #Oncology
June 8, 2025 at 9:44 AM
🧠 June 8 is #WorldBrainTumorDay — raising awareness & understanding of brain tumors.
EANO supports progress in #NeuroOncology through research, education & collaboration.
🔗 Learn more: www.eano.eu
#btsm #BrainTumor #Oncology
EANO supports progress in #NeuroOncology through research, education & collaboration.
🔗 Learn more: www.eano.eu
#btsm #BrainTumor #Oncology
Reposted by MILO Lab
A Perspective on a dynamic and multimodal framework to define microglial states from @rsankowski.bsky.social and Marco Prinz
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A dynamic and multimodal framework to define microglial states - Nature Neuroscience
Sankowski and Prinz propose a classification framework for microglia states that considers the contextual plasticity of microglia. Their multimodal classification aligns a robust terminology with biol...
www.nature.com
May 20, 2025 at 4:37 PM
A Perspective on a dynamic and multimodal framework to define microglial states from @rsankowski.bsky.social and Marco Prinz
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by MILO Lab
We had an amazing lab retreat Spring 2025! Best team of the world!
April 7, 2025 at 6:57 PM
We had an amazing lab retreat Spring 2025! Best team of the world!
Reposted by MILO Lab
The @milolab.bsky.social retreat was lit 🔥. I am grateful and lucky to be in this amazing group.
Great people, great science.
#glioblastoma #spatialtranscriptomics
#scRNA-seq
Great people, great science.
#glioblastoma #spatialtranscriptomics
#scRNA-seq
We had an amazing lab retreat Spring 2025! Best team of the world!
April 7, 2025 at 9:29 PM
The @milolab.bsky.social retreat was lit 🔥. I am grateful and lucky to be in this amazing group.
Great people, great science.
#glioblastoma #spatialtranscriptomics
#scRNA-seq
Great people, great science.
#glioblastoma #spatialtranscriptomics
#scRNA-seq
Reposted by MILO Lab
Grade = microenvironment under a microscope, so we looked to see what specific environments in the tumor were associated w/specific myeloid activities using 10X Visium data from @milolab.bsky.social .Our Scavenger Suppressive program was only in hypoxia. The Complement Suppressive? Everywhere else
February 27, 2025 at 4:05 AM
Grade = microenvironment under a microscope, so we looked to see what specific environments in the tumor were associated w/specific myeloid activities using 10X Visium data from @milolab.bsky.social .Our Scavenger Suppressive program was only in hypoxia. The Complement Suppressive? Everywhere else
Reposted by MILO Lab
Proud to share our @nature.com paper, co-led by Chadi El Farran & Charles Couturier under mentorship of Brad Bernstein where we develop a new framework to understand immunomodulatory myeloid cells in #glioma & lay a foundation to develop more effective immunotherapies. www.nature.com/articles/s41...
Programs, origins and immunomodulatory functions of myeloid cells in glioma - Nature
A study of myeloid cells in gliomas, a type of brain tumour, used a factor-based computational framework to reveal four immunomodulatory gene-expression programs that are expressed across myeloid cell...
www.nature.com
February 27, 2025 at 4:05 AM
Proud to share our @nature.com paper, co-led by Chadi El Farran & Charles Couturier under mentorship of Brad Bernstein where we develop a new framework to understand immunomodulatory myeloid cells in #glioma & lay a foundation to develop more effective immunotherapies. www.nature.com/articles/s41...
Reposted by MILO Lab
Delighted to share the published version of this work from brilliant #CancerNeuroscience post-doc Tara Barron detailing GABAergic neuron-to-glioma synapses in #DIPG/#DMG. 🧵
Open access link:
www.nature.com/articles/s41...
Open access link:
www.nature.com/articles/s41...
February 19, 2025 at 9:41 PM
Delighted to share the published version of this work from brilliant #CancerNeuroscience post-doc Tara Barron detailing GABAergic neuron-to-glioma synapses in #DIPG/#DMG. 🧵
Open access link:
www.nature.com/articles/s41...
Open access link:
www.nature.com/articles/s41...
Reposted by MILO Lab
1/5 Excited to share our latest paper published in EMBO Molecular Medicine!🎉 🎉 embopress.org/doi/full/10....
This collaborative work brings together Team1 BRIC_Bordeaux, @ahmadsharanek.bsky.social, Andreas Bikfalvi, Lucie Brisson, Thomas Mathivet and our GBmetabo Team with Audrey Burban
This collaborative work brings together Team1 BRIC_Bordeaux, @ahmadsharanek.bsky.social, Andreas Bikfalvi, Lucie Brisson, Thomas Mathivet and our GBmetabo Team with Audrey Burban
Exploiting metabolic vulnerability in glioblastoma using a brain-penetrant drug with a safe profile | EMBO Molecular Medicine
imageimageIn patient-derived and animal tumour models, mubritinib suppressed glioblastoma stem
cells and tumour growth by targeting mitochondrial respiration. Combination with the
current standard of ...
embopress.org
February 4, 2025 at 8:40 PM
1/5 Excited to share our latest paper published in EMBO Molecular Medicine!🎉 🎉 embopress.org/doi/full/10....
This collaborative work brings together Team1 BRIC_Bordeaux, @ahmadsharanek.bsky.social, Andreas Bikfalvi, Lucie Brisson, Thomas Mathivet and our GBmetabo Team with Audrey Burban
This collaborative work brings together Team1 BRIC_Bordeaux, @ahmadsharanek.bsky.social, Andreas Bikfalvi, Lucie Brisson, Thomas Mathivet and our GBmetabo Team with Audrey Burban
Ever wondered what makes brain tumors tick?
Excited by the breakthroughs in spatial transcriptomics and single-cell analysis? Follow @milolab.bsky.social account on Instagram: cutting-edge insights, updates, and engaging content!
www.instagram.com/the_milolab/...
Excited by the breakthroughs in spatial transcriptomics and single-cell analysis? Follow @milolab.bsky.social account on Instagram: cutting-edge insights, updates, and engaging content!
www.instagram.com/the_milolab/...
Login • Instagram
Welcome back to Instagram. Sign in to check out what your friends, family & interests have been capturing & sharing around the world.
www.instagram.com
January 30, 2025 at 7:22 PM
Ever wondered what makes brain tumors tick?
Excited by the breakthroughs in spatial transcriptomics and single-cell analysis? Follow @milolab.bsky.social account on Instagram: cutting-edge insights, updates, and engaging content!
www.instagram.com/the_milolab/...
Excited by the breakthroughs in spatial transcriptomics and single-cell analysis? Follow @milolab.bsky.social account on Instagram: cutting-edge insights, updates, and engaging content!
www.instagram.com/the_milolab/...
Happy to share our recent investigation of the spatial architecture of benign and malignant peripheral nerve sheath tumors.
@10xGenomics
🚨Spoiler Alert: We identified APOD in neurofibroma regions as a novel biomarker in hybrid PNSTs
t.co/GmA9MLNKy1
@10xGenomics
🚨Spoiler Alert: We identified APOD in neurofibroma regions as a novel biomarker in hybrid PNSTs
t.co/GmA9MLNKy1
January 30, 2025 at 7:19 PM
Happy to share our recent investigation of the spatial architecture of benign and malignant peripheral nerve sheath tumors.
@10xGenomics
🚨Spoiler Alert: We identified APOD in neurofibroma regions as a novel biomarker in hybrid PNSTs
t.co/GmA9MLNKy1
@10xGenomics
🚨Spoiler Alert: We identified APOD in neurofibroma regions as a novel biomarker in hybrid PNSTs
t.co/GmA9MLNKy1
Happy to share your latest collaboration with
@sahm_lab
leveraging spatial transcriptomics
@10xGenomics
for neuropathology diagnosis #DeepLearning
! 107 patients across 15 CNS tumors!
www.nature.com/articles/s43...
@sahm_lab
leveraging spatial transcriptomics
@10xGenomics
for neuropathology diagnosis #DeepLearning
! 107 patients across 15 CNS tumors!
www.nature.com/articles/s43...
Spatially resolved transcriptomics and graph-based deep learning improve accuracy of routine CNS tumor diagnostics - Nature Cancer
Ritter et al. present a spatial transcriptomics and deep learning-based approach named NePSTA (neuropathology spatial transcriptomic analysis) and leverage it to improve neuropathological diagnostics ...
www.nature.com
January 30, 2025 at 3:28 PM
Happy to share your latest collaboration with
@sahm_lab
leveraging spatial transcriptomics
@10xGenomics
for neuropathology diagnosis #DeepLearning
! 107 patients across 15 CNS tumors!
www.nature.com/articles/s43...
@sahm_lab
leveraging spatial transcriptomics
@10xGenomics
for neuropathology diagnosis #DeepLearning
! 107 patients across 15 CNS tumors!
www.nature.com/articles/s43...
Reposted by MILO Lab
🧵Just in time for
: New research from the Venkataramani lab @CellCellPress
maps how brain tumor cells create extensive neural networks in glioblastoma. Check out our paper here: authors.elsevier.com/sd/article/S...
@ekinreyhan.bsky.social
@svenjaktetzlaff.bsky.social
1/15
: New research from the Venkataramani lab @CellCellPress
maps how brain tumor cells create extensive neural networks in glioblastoma. Check out our paper here: authors.elsevier.com/sd/article/S...
@ekinreyhan.bsky.social
@svenjaktetzlaff.bsky.social
1/15
December 6, 2024 at 11:18 PM
🧵Just in time for
: New research from the Venkataramani lab @CellCellPress
maps how brain tumor cells create extensive neural networks in glioblastoma. Check out our paper here: authors.elsevier.com/sd/article/S...
@ekinreyhan.bsky.social
@svenjaktetzlaff.bsky.social
1/15
: New research from the Venkataramani lab @CellCellPress
maps how brain tumor cells create extensive neural networks in glioblastoma. Check out our paper here: authors.elsevier.com/sd/article/S...
@ekinreyhan.bsky.social
@svenjaktetzlaff.bsky.social
1/15
Reposted by MILO Lab
Amazing talk by
Henrik Heiland
on using #spatialtranscriptomics data to model glioblastoma evolution #SNO2024
Henrik Heiland
on using #spatialtranscriptomics data to model glioblastoma evolution #SNO2024
November 22, 2024 at 10:14 PM
Amazing talk by
Henrik Heiland
on using #spatialtranscriptomics data to model glioblastoma evolution #SNO2024
Henrik Heiland
on using #spatialtranscriptomics data to model glioblastoma evolution #SNO2024