mesoSPIM: Clear Images. Big samples. Open source.
@mesospim.bsky.social
Light-sheet microscopes for large samples. Open source hardware and software. Run by @nvladimus.bsky.social and @voigtvision.bsky.social
Overview: www.mesospim.org
Mailing list: http://eepurl.com/hPBRhj
Forum: forum.image.sc/tag/mesospim
Overview: www.mesospim.org
Mailing list: http://eepurl.com/hPBRhj
Forum: forum.image.sc/tag/mesospim
Pinned
Final program of the 10-year #mesoSPIM2025 Anniversary Symposium, October 13-15 in Zurich! Amazing lineup of speakers: biologists, physicists, developers, computer scientists and industry experts! Join us to learn, present, and connect! Registration until Sept. 15. www.adabd.uzh.ch/en/events/me...
The 10 Years of #mesoSPIM Symposium was a blast! 🔟🎂The excitement was palpable, and we were all inspired. Three days flew by fast! Thanks to all the attendees, speakers, organizing team, and our sponsors for making it such a memorable event! Let's shape the next 10y of microscopy together! 💪❤️🔬
October 16, 2025 at 3:43 PM
The 10 Years of #mesoSPIM Symposium was a blast! 🔟🎂The excitement was palpable, and we were all inspired. Three days flew by fast! Thanks to all the attendees, speakers, organizing team, and our sponsors for making it such a memorable event! Let's shape the next 10y of microscopy together! 💪❤️🔬
Job opportunity at the University of Zurich! 📢
We are looking for a 𝐋𝐚𝐛𝐨𝐫𝐚𝐭𝐨𝐫𝐲 𝐓𝐞𝐜𝐡𝐧𝐢𝐜𝐢𝐚𝐧 / 𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡 𝐀𝐬𝐬𝐢𝐬𝐭𝐚𝐧𝐭 (𝟒𝟎%) to join our Microscopy Innovation Platform (MIP), an open-source initiative focused on advancing and making light-sheet and multiphoton microscopy accessible to researchers.
1/3
We are looking for a 𝐋𝐚𝐛𝐨𝐫𝐚𝐭𝐨𝐫𝐲 𝐓𝐞𝐜𝐡𝐧𝐢𝐜𝐢𝐚𝐧 / 𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡 𝐀𝐬𝐬𝐢𝐬𝐭𝐚𝐧𝐭 (𝟒𝟎%) to join our Microscopy Innovation Platform (MIP), an open-source initiative focused on advancing and making light-sheet and multiphoton microscopy accessible to researchers.
1/3
October 10, 2025 at 8:58 AM
Job opportunity at the University of Zurich! 📢
We are looking for a 𝐋𝐚𝐛𝐨𝐫𝐚𝐭𝐨𝐫𝐲 𝐓𝐞𝐜𝐡𝐧𝐢𝐜𝐢𝐚𝐧 / 𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡 𝐀𝐬𝐬𝐢𝐬𝐭𝐚𝐧𝐭 (𝟒𝟎%) to join our Microscopy Innovation Platform (MIP), an open-source initiative focused on advancing and making light-sheet and multiphoton microscopy accessible to researchers.
1/3
We are looking for a 𝐋𝐚𝐛𝐨𝐫𝐚𝐭𝐨𝐫𝐲 𝐓𝐞𝐜𝐡𝐧𝐢𝐜𝐢𝐚𝐧 / 𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡 𝐀𝐬𝐬𝐢𝐬𝐭𝐚𝐧𝐭 (𝟒𝟎%) to join our Microscopy Innovation Platform (MIP), an open-source initiative focused on advancing and making light-sheet and multiphoton microscopy accessible to researchers.
1/3
Is it possible to stain specific proteins and cell types in old formalin-fixed human tissues and make them transparent for light-sheet imaging and clinical 3D diagnostics?
🧵 1/3
🧵 1/3
August 27, 2025 at 10:32 AM
Is it possible to stain specific proteins and cell types in old formalin-fixed human tissues and make them transparent for light-sheet imaging and clinical 3D diagnostics?
🧵 1/3
🧵 1/3
Final program of the 10-year #mesoSPIM2025 Anniversary Symposium, October 13-15 in Zurich! Amazing lineup of speakers: biologists, physicists, developers, computer scientists and industry experts! Join us to learn, present, and connect! Registration until Sept. 15. www.adabd.uzh.ch/en/events/me...
August 22, 2025 at 3:36 PM
Final program of the 10-year #mesoSPIM2025 Anniversary Symposium, October 13-15 in Zurich! Amazing lineup of speakers: biologists, physicists, developers, computer scientists and industry experts! Join us to learn, present, and connect! Registration until Sept. 15. www.adabd.uzh.ch/en/events/me...
📣We have opened our official User Forum: forum.image.sc/tag/mesospim
In this forum you can connect with 🔬developers and the image analysis experts. Ask your burning questions about the #mesoSPIM hardware, software, and image processing, or help the beginners to get started!
Tip: use project tags!
In this forum you can connect with 🔬developers and the image analysis experts. Ask your burning questions about the #mesoSPIM hardware, software, and image processing, or help the beginners to get started!
Tip: use project tags!
Topics tagged mesospim
Topics tagged mesospim
forum.image.sc
August 22, 2025 at 8:04 AM
📣We have opened our official User Forum: forum.image.sc/tag/mesospim
In this forum you can connect with 🔬developers and the image analysis experts. Ask your burning questions about the #mesoSPIM hardware, software, and image processing, or help the beginners to get started!
Tip: use project tags!
In this forum you can connect with 🔬developers and the image analysis experts. Ask your burning questions about the #mesoSPIM hardware, software, and image processing, or help the beginners to get started!
Tip: use project tags!
How to image across scales from organs to synapses, unravel biological mechanisms and handle massive data?
Learn more from @adamkglaser.bsky.social, senior scientist at the Allen Institute and the lead developer of #ExA-SPIM technique, at the #mesoSPIM2025 Symposium, Oct 13-15.
Learn more from @adamkglaser.bsky.social, senior scientist at the Allen Institute and the lead developer of #ExA-SPIM technique, at the #mesoSPIM2025 Symposium, Oct 13-15.
August 20, 2025 at 11:38 AM
How to image across scales from organs to synapses, unravel biological mechanisms and handle massive data?
Learn more from @adamkglaser.bsky.social, senior scientist at the Allen Institute and the lead developer of #ExA-SPIM technique, at the #mesoSPIM2025 Symposium, Oct 13-15.
Learn more from @adamkglaser.bsky.social, senior scientist at the Allen Institute and the lead developer of #ExA-SPIM technique, at the #mesoSPIM2025 Symposium, Oct 13-15.
💥How can light-sheet help reveal dark matter?💥
Join Prof. Laura Baudis @lbaudis.bsky.social at #mesoSPIM Symposium, Oct 13–15 in Zurich or online, to see how light-sheet fluorescence microscopy 🔬 is used to image nuclear ☢️ recoil tracks to detect elusive particles!
Register now: t.uzh.ch/1Ss
Join Prof. Laura Baudis @lbaudis.bsky.social at #mesoSPIM Symposium, Oct 13–15 in Zurich or online, to see how light-sheet fluorescence microscopy 🔬 is used to image nuclear ☢️ recoil tracks to detect elusive particles!
Register now: t.uzh.ch/1Ss
August 18, 2025 at 9:28 AM
💥How can light-sheet help reveal dark matter?💥
Join Prof. Laura Baudis @lbaudis.bsky.social at #mesoSPIM Symposium, Oct 13–15 in Zurich or online, to see how light-sheet fluorescence microscopy 🔬 is used to image nuclear ☢️ recoil tracks to detect elusive particles!
Register now: t.uzh.ch/1Ss
Join Prof. Laura Baudis @lbaudis.bsky.social at #mesoSPIM Symposium, Oct 13–15 in Zurich or online, to see how light-sheet fluorescence microscopy 🔬 is used to image nuclear ☢️ recoil tracks to detect elusive particles!
Register now: t.uzh.ch/1Ss
Reposted by mesoSPIM: Clear Images. Big samples. Open source.
#Deeplearning-based #CRISPR DNA integration and editing by Thomas Naert & Sören Lienkamp & Co with lots of @mesospim.bsky.social #lightsheet #Microscopy data of tadpoles (and some taken with the #Schmidt #multiimmersion objective prototype!) 🔬🐸 www.nature.com/articles/s41...
August 13, 2025 at 2:09 PM
#Deeplearning-based #CRISPR DNA integration and editing by Thomas Naert & Sören Lienkamp & Co with lots of @mesospim.bsky.social #lightsheet #Microscopy data of tadpoles (and some taken with the #Schmidt #multiimmersion objective prototype!) 🔬🐸 www.nature.com/articles/s41...
We’re excited to welcome @kevin-dean.bsky.social to the #mesoSPIM2025 Symposium! Explore his innovations in Multiscale Cleared-Tissue Axially Swept Light-Sheet Microscopy for imaging from organ to subcellular levels.
🗺️Oct 13–15 | Zurich & hybrid
Interested? Register now: t.uzh.ch/1Ss
🗺️Oct 13–15 | Zurich & hybrid
Interested? Register now: t.uzh.ch/1Ss
August 12, 2025 at 9:50 AM
We’re excited to welcome @kevin-dean.bsky.social to the #mesoSPIM2025 Symposium! Explore his innovations in Multiscale Cleared-Tissue Axially Swept Light-Sheet Microscopy for imaging from organ to subcellular levels.
🗺️Oct 13–15 | Zurich & hybrid
Interested? Register now: t.uzh.ch/1Ss
🗺️Oct 13–15 | Zurich & hybrid
Interested? Register now: t.uzh.ch/1Ss
Abstract Submission Deadline: TOMORROW, July 15-th 🎇
🎉 Call for Abstracts! 🎉
Abstract deadline approaching! 10 years of #mesoSPIM initiative – join us at the symposium for talks, demos & posters on microscopy, tissue clearing, and data analysis!
📆 October 13-15, 2025
🗺️ Zurich, Switzerland, but also online.
www.adabd.uzh.ch/en/events/me...
Abstract deadline approaching! 10 years of #mesoSPIM initiative – join us at the symposium for talks, demos & posters on microscopy, tissue clearing, and data analysis!
📆 October 13-15, 2025
🗺️ Zurich, Switzerland, but also online.
www.adabd.uzh.ch/en/events/me...
July 14, 2025 at 10:17 AM
Abstract Submission Deadline: TOMORROW, July 15-th 🎇
🎉 Call for Abstracts! 🎉
Abstract deadline approaching! 10 years of #mesoSPIM initiative – join us at the symposium for talks, demos & posters on microscopy, tissue clearing, and data analysis!
📆 October 13-15, 2025
🗺️ Zurich, Switzerland, but also online.
www.adabd.uzh.ch/en/events/me...
Abstract deadline approaching! 10 years of #mesoSPIM initiative – join us at the symposium for talks, demos & posters on microscopy, tissue clearing, and data analysis!
📆 October 13-15, 2025
🗺️ Zurich, Switzerland, but also online.
www.adabd.uzh.ch/en/events/me...
July 3, 2025 at 10:27 AM
🎉 Call for Abstracts! 🎉
Abstract deadline approaching! 10 years of #mesoSPIM initiative – join us at the symposium for talks, demos & posters on microscopy, tissue clearing, and data analysis!
📆 October 13-15, 2025
🗺️ Zurich, Switzerland, but also online.
www.adabd.uzh.ch/en/events/me...
Abstract deadline approaching! 10 years of #mesoSPIM initiative – join us at the symposium for talks, demos & posters on microscopy, tissue clearing, and data analysis!
📆 October 13-15, 2025
🗺️ Zurich, Switzerland, but also online.
www.adabd.uzh.ch/en/events/me...
🎉 Call for Abstracts! 🎉
We’re celebrating 10 years of #mesoSPIM #opensource initiative – join us at the symposium for talks, demos & posters on open-source light-sheet microscopy, tissue clearing, and imaging!
Dates: October 13-15, 2025
Location: Zurich, Switzerland
Registration: ema.uzh.ch/R7YRN
We’re celebrating 10 years of #mesoSPIM #opensource initiative – join us at the symposium for talks, demos & posters on open-source light-sheet microscopy, tissue clearing, and imaging!
Dates: October 13-15, 2025
Location: Zurich, Switzerland
Registration: ema.uzh.ch/R7YRN
June 12, 2025 at 9:15 AM
🎉 Call for Abstracts! 🎉
We’re celebrating 10 years of #mesoSPIM #opensource initiative – join us at the symposium for talks, demos & posters on open-source light-sheet microscopy, tissue clearing, and imaging!
Dates: October 13-15, 2025
Location: Zurich, Switzerland
Registration: ema.uzh.ch/R7YRN
We’re celebrating 10 years of #mesoSPIM #opensource initiative – join us at the symposium for talks, demos & posters on open-source light-sheet microscopy, tissue clearing, and imaging!
Dates: October 13-15, 2025
Location: Zurich, Switzerland
Registration: ema.uzh.ch/R7YRN
Reposted by mesoSPIM: Clear Images. Big samples. Open source.
🔬 On June 6, we inaugurated the first #MesoSPIM in France at INRAE Jouy-en-Josas & ENS Paris-Saclay! A big thanks to @nvladimus.bsky.social , @mgarbelli.bsky.social ,Angeliki Vavladeli & all speakers and sponsors. Exciting step forward for #opensource imaging & interdisciplinary science! #microscopy
June 10, 2025 at 10:34 AM
🔬 On June 6, we inaugurated the first #MesoSPIM in France at INRAE Jouy-en-Josas & ENS Paris-Saclay! A big thanks to @nvladimus.bsky.social , @mgarbelli.bsky.social ,Angeliki Vavladeli & all speakers and sponsors. Exciting step forward for #opensource imaging & interdisciplinary science! #microscopy
Did you know that Universite Paris Saclay has its own Benchtop #mesoSPIM? Interdisciplinary team lead by @christellelangevin.bsky.social has built their own setup, the first in France, and organized an inauguration symposium! Cleared baby sturgeon or trout? They have it! French bioimaging is strong!
June 7, 2025 at 11:23 AM
Did you know that Universite Paris Saclay has its own Benchtop #mesoSPIM? Interdisciplinary team lead by @christellelangevin.bsky.social has built their own setup, the first in France, and organized an inauguration symposium! Cleared baby sturgeon or trout? They have it! French bioimaging is strong!
Reposted by mesoSPIM: Clear Images. Big samples. Open source.
New chamber mount design for our @mesospim.bsky.social - magnetic kinematic bases from @thorlabs.bsky.social for the win! 3D printed (for now) bases hold the chamber snugly for precise positioning between experiments. Fill port on the front allows for media addition without disturbing imaging.
June 3, 2025 at 7:09 PM
New chamber mount design for our @mesospim.bsky.social - magnetic kinematic bases from @thorlabs.bsky.social for the win! 3D printed (for now) bases hold the chamber snugly for precise positioning between experiments. Fill port on the front allows for media addition without disturbing imaging.
Reposted by mesoSPIM: Clear Images. Big samples. Open source.
Looking forward to the @mesospim.bsky.social #lightsheet #Microscopy anniversary symposium in October with @preibischs.bsky.social @adamkglaser.bsky.social @christellelangevin.bsky.social & many more! And to the next mesoSPIM decade! 🔬 Thanks @nvladimus.bsky.social & Co for organizing it!
May 16, 2025 at 12:15 PM
Looking forward to the @mesospim.bsky.social #lightsheet #Microscopy anniversary symposium in October with @preibischs.bsky.social @adamkglaser.bsky.social @christellelangevin.bsky.social & many more! And to the next mesoSPIM decade! 🔬 Thanks @nvladimus.bsky.social & Co for organizing it!
Reposted by mesoSPIM: Clear Images. Big samples. Open source.
I'm excited to be able to be in Zurich for the mesoSPIM symposium. This is a really fantastic project.
May 15, 2025 at 6:24 PM
I'm excited to be able to be in Zurich for the mesoSPIM symposium. This is a really fantastic project.
Reposted by mesoSPIM: Clear Images. Big samples. Open source.
The culmination of years of hard work by Anna Maria Reuss & Co: aDISCO - a protocol for clearing & antibody-staining human formalin-fixed paraffin-embedded (FFPE) tissue! With lots of @mesospim.bsky.social #lightsheet #Microscopy @ptrrupprecht.bsky.social & many more!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
May 27, 2025 at 7:30 AM
The culmination of years of hard work by Anna Maria Reuss & Co: aDISCO - a protocol for clearing & antibody-staining human formalin-fixed paraffin-embedded (FFPE) tissue! With lots of @mesospim.bsky.social #lightsheet #Microscopy @ptrrupprecht.bsky.social & many more!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by mesoSPIM: Clear Images. Big samples. Open source.
Have you heard about #MesoSPIM microscopy platforms for imaging cleared tissue?
Join us to learn more about this #opensource #lightscheet device specific features, applications and discuss current challenges with experts in the field.
#3Dimaging #LightSheet #TissueClearing #AI #DataScience #R&D
Join us to learn more about this #opensource #lightscheet device specific features, applications and discuss current challenges with experts in the field.
#3Dimaging #LightSheet #TissueClearing #AI #DataScience #R&D
April 29, 2025 at 5:01 AM
Have you heard about #MesoSPIM microscopy platforms for imaging cleared tissue?
Join us to learn more about this #opensource #lightscheet device specific features, applications and discuss current challenges with experts in the field.
#3Dimaging #LightSheet #TissueClearing #AI #DataScience #R&D
Join us to learn more about this #opensource #lightscheet device specific features, applications and discuss current challenges with experts in the field.
#3Dimaging #LightSheet #TissueClearing #AI #DataScience #R&D
Want to learn about #mesoSPIM imaging initiative and network with microscopy and data analysis experts? Come to Paris-Saclay on June 6-th! Meet our team there! Registration is still open (and free)! mesospim-upas.sciencesconf.org
April 29, 2025 at 9:35 AM
Want to learn about #mesoSPIM imaging initiative and network with microscopy and data analysis experts? Come to Paris-Saclay on June 6-th! Meet our team there! Registration is still open (and free)! mesospim-upas.sciencesconf.org
Reposted by mesoSPIM: Clear Images. Big samples. Open source.
This is an image of a healthy mouse kidney, imaged on the MesoSPIM 4x objective.
#microscopymonday #microscopy #fluorescentproteins #lightsheet 🧪 🤝 🍎 👩🔬 #NephSky #RenalSky
Image courtesy of @mdibl-lmf.bsky.social
#microscopymonday #microscopy #fluorescentproteins #lightsheet 🧪 🤝 🍎 👩🔬 #NephSky #RenalSky
Image courtesy of @mdibl-lmf.bsky.social
March 10, 2025 at 12:01 PM
This is an image of a healthy mouse kidney, imaged on the MesoSPIM 4x objective.
#microscopymonday #microscopy #fluorescentproteins #lightsheet 🧪 🤝 🍎 👩🔬 #NephSky #RenalSky
Image courtesy of @mdibl-lmf.bsky.social
#microscopymonday #microscopy #fluorescentproteins #lightsheet 🧪 🤝 🍎 👩🔬 #NephSky #RenalSky
Image courtesy of @mdibl-lmf.bsky.social
New release of #mesoSPIM control software! Major bug fixes and performance improvement. github.com/mesoSPIM/mes...
March 10, 2025 at 10:37 AM
New release of #mesoSPIM control software! Major bug fixes and performance improvement. github.com/mesoSPIM/mes...
Some good news: 3 new Benchtop #mesoSPIM are being built!
Scientists in China, USA, and Czech Republic are building the beautiful open-source beasts for their research.
South America, what are you waiting for? Australia? Greenland?
mesospim.org/setups/
Scientists in China, USA, and Czech Republic are building the beautiful open-source beasts for their research.
South America, what are you waiting for? Australia? Greenland?
mesospim.org/setups/
February 14, 2025 at 2:01 PM
Some good news: 3 new Benchtop #mesoSPIM are being built!
Scientists in China, USA, and Czech Republic are building the beautiful open-source beasts for their research.
South America, what are you waiting for? Australia? Greenland?
mesospim.org/setups/
Scientists in China, USA, and Czech Republic are building the beautiful open-source beasts for their research.
South America, what are you waiting for? Australia? Greenland?
mesospim.org/setups/
New experimental feature: timelapse for #mesoSPIM! Because why not? You can now image live specimen, such as developing organisms. Checkout this SW version at:
github.com/mesoSPIM/mes...
and let us know how it works for you. Be brave!
github.com/mesoSPIM/mes...
and let us know how it works for you. Be brave!
February 5, 2025 at 3:33 PM
New experimental feature: timelapse for #mesoSPIM! Because why not? You can now image live specimen, such as developing organisms. Checkout this SW version at:
github.com/mesoSPIM/mes...
and let us know how it works for you. Be brave!
github.com/mesoSPIM/mes...
and let us know how it works for you. Be brave!
Reposted by mesoSPIM: Clear Images. Big samples. Open source.
"Zebrafish head"
In this captivating image, we can see the labeling of blood vessels in the head of a #zebrafish. Taken by Marko Pende on the #mesoSPIM in December 2022.
#flourescencefriday 🐟🎸 🧪🤝 #microscopy #fluorescentproteins #lightsheet
In this captivating image, we can see the labeling of blood vessels in the head of a #zebrafish. Taken by Marko Pende on the #mesoSPIM in December 2022.
#flourescencefriday 🐟🎸 🧪🤝 #microscopy #fluorescentproteins #lightsheet
January 24, 2025 at 2:20 PM
"Zebrafish head"
In this captivating image, we can see the labeling of blood vessels in the head of a #zebrafish. Taken by Marko Pende on the #mesoSPIM in December 2022.
#flourescencefriday 🐟🎸 🧪🤝 #microscopy #fluorescentproteins #lightsheet
In this captivating image, we can see the labeling of blood vessels in the head of a #zebrafish. Taken by Marko Pende on the #mesoSPIM in December 2022.
#flourescencefriday 🐟🎸 🧪🤝 #microscopy #fluorescentproteins #lightsheet