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meineckelab.bsky.social
MeineckeLab
@meineckelab.bsky.social
We are interested in membranes, mitochondria and membrane proteins.
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We had a great evening showing and discussing Picture a Scientist. It’s such an important topic, and we’re grateful for the big turnout, the lively discussion, and especially to Cristina (@cpaulino.bsky.social) and Alba (@diz-lab.bsky.social) for their thoughtful and engaging moderation!
October 9, 2025 at 5:56 AM
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Now @bzh-hd.bsky.social Jonathan Friedman is talking in #mitochondria organization
September 23, 2025 at 10:14 AM
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Tomorrow at the BZH:
We’re thrilled to host Jonathan Friedman (@labfriedman.bsky.social), who will present his latest research on mitochondrial biology.

📅 23.09.25 & 12:15
📍 BZH Heidelberg

Join us to explore fresh insights into how mitochondria shape cellular life!
September 22, 2025 at 8:17 AM
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Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism.
www.nature.com/articles/s41...
August 21, 2025 at 5:19 AM
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Thrilled to have contributed to this amazing work! Thanks for having us on board 🙌 Huge shoutout to our super-talented postdoc #MelanieKönig for her outstanding efforts 💫. And big congratulations to everyone involved in this terrific team effort! 🎉 @sfb1638.bsky.social @bzh-hd.bsky.social
August 22, 2025 at 5:38 PM
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📢 Tomorrow at the BZH: Don’t miss Chris Stefan from UCL presenting his latest research as part of our #SFB1638 Seminar Series! 🧬 A great chance to hear cutting-edge science and connect with the community. See you there!
June 2, 2025 at 3:48 PM
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Researchers in Science have developed a tool to silence specific mitochondria-encoded mRNAs in living cells, which could help scientists understand the origins of certain mitochondria-related diseases. scim.ag/3F6Wm5d
Silencing mitochondrial gene expression in living cells
Mitochondria fulfill central functions in metabolism and energy supply. They express their own genome, which encodes key subunits of the oxidative phosphorylation system. However, central mechanisms u...
scim.ag
May 23, 2025 at 7:23 PM
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Huge congratulations to Kerstin and Oliver and the entire team on your success in the Excellence Initiative! Well-deserved recognition and strong support for groundbreaking science ahead.
#SynthImmune is getting real! Super excited that our excellence cluster got funded today @dfg.de Thanks to everyone involved @uniheidelberg.bsky.social, especially @dimichelelab1.bsky.social and Oliver Fackler!
May 23, 2025 at 4:12 AM
Great initiative by @uniheidelberg.bsky.social to promote collaborative efforts in life science! Enjoyed sharing insights on our Membrane SFB (Collaborative Research Center). Always a pleasure to discuss our work on membrane dynamics.
Our PIs Kerstin (@kgoepfrich.bsky.social) and Michael (@meineckelab.bsky.social) joined Wolfgang Heim to talk about scientific CVs, engaging in public outreach and the wonders of cellular membrane remodelling. Don’t miss the SFB1638 edition of Überlebensstrategien — now streaming!
SFB 1638 Umbau von zellulären Membranen – wie veränderte Form Funktion schafft
YouTube video by UniHeidelberg
www.youtube.com
May 20, 2025 at 5:32 AM
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Just back from the Jacques Monod Conference on Membrane Remodeling in Roscoff—an inspiring trip for Sebastian Schuck and Michael Meinecke (@meineckelab)! We had exciting science, engaged in inspiring discussions, and enjoyed the stunning setting. There’s nothing quite like membrane research.
May 16, 2025 at 3:57 PM
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Our SFB1638 PI Kerstin Göpfrich (@kgoepfrich.bsky.social) joined Gert #Scobel and Tobias Erb to explore the future of synthetic biology—its promise, challenges, and big ideas. Catch the super interesting discussion on @3sat (@3sat.bluesky.com.de)

www.3sat.de/wissen/scobe...
Biologie aus dem Baukasten
Ingenieure, Informatiker, Chemiker und Biologen kreieren künstliche biologische Systeme. Die synthetische Biologie verändert die Zukunft und definiert die Grenzen der Wissenschaft neu.
www.3sat.de
April 29, 2025 at 1:46 PM
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An exciting new approach in single-cell metabolomics from two SFB1638 groups! Carsten Hopf’s group from CeMOS with support from the Göpfrich lab (@kgoepfrich.bsky.social) unveil tech that tracks brain cell changes linked to neurodegeneration.

advanced.onlinelibrary.wiley.com/doi/10.1002/...
Mass‐Guided Single‐Cell MALDI Imaging of Low‐Mass Metabolites Reveals Cellular Activation Markers
The PRISM-MS workflow transforms single-cell mass spectrometry imaging by allowing detailed analysis of low-mass metabolites in large cell populations without metabolite degradation. By introducing n...
advanced.onlinelibrary.wiley.com
April 28, 2025 at 5:42 AM
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Out today, we report how small chemical modifications in the metabolism of ergosterol are needed for yeast membranes to phase seperate into ordered yet fluid domains www.science.org/doi/10.1126/... (1/n)
Structural dissection of ergosterol metabolism reveals a pathway optimized for membrane phase separation
The metabolism of ergosterol shapes this lipid to allow the formation of fluid membrane domains in yeast cells.
www.science.org
April 24, 2025 at 3:04 PM
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🚨 Lipid Time! 🚨
Excited to share our latest story now on @biorxiv-biochem.bsky.social !
Our brilliant PhD student @manpreet0700.bsky.social , together with @walter-nickel-bzh.bsky.social and myself, shows how PI(4,5)P₂ asymmetry in the plasma membrane drives the unconventional secretion of FGF2!
👇👇👇
Plasma membrane transbilayer asymmetry of PI(4,5)P2 drives unconventional secretion of Fibroblast Growth Factor 2
Unconventional secretion of Fibroblast Growth Factor 2 (FGF2) is based upon direct self-translocation across the plasma membrane, a process that involves the transient formation of a lipidic membrane ...
www.biorxiv.org
April 21, 2025 at 11:59 PM
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Static structures are out. A new publication from the Ellenberg lab ( @ellenberglab.bsky.social, @embl.org , @sfb1638.bsky.social ) and Andrej Sali shows how integrative spatiotemporal modeling captures molecular motion in 4D, unlocking dynamic views of nuclear pore complex assembly.
www.pnas.org
April 14, 2025 at 2:19 PM
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Lovely start into our new #SFB1638 on cellular membrane remodeling with a two-day kick-off meeting at the International Academic Forum Heidelberg (IWH). Many thanks to our speaker @meineckelab.bsky.social and team for the great organization.
April 9, 2025 at 4:51 PM
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Thrilled to share the structure of dimerised human PINK1 docked to an endogenous translocase array on the mitochondrial surface, composed of two TOM complexes, bridged by a VDAC2 dimer! Published today in Science www.science.org/doi/10.1126/...

@wehi-research.bsky.social @komanderlab.bsky.social
March 13, 2025 at 7:20 PM