Matteo Guardamagna
@matteoguardamagna.bsky.social
Circuits, Manifolds & Development 🐭
Solberg Postdoc Fellow in the Moser Lab
~ Developmental Systems Neuroscience ~
Solberg Postdoc Fellow in the Moser Lab
~ Developmental Systems Neuroscience ~
Pinned
How does the brain's spatial navigation system develop? I had so many fun discussions with the incredible communities at Johns Hopkins and Columbia this past week - a lot of exciting ideas for experimental and theoretical work ahead.
Grateful to be hosted by @kavlifoundation.org @lorenzoposani.com
Grateful to be hosted by @kavlifoundation.org @lorenzoposani.com
Reposted by Matteo Guardamagna
A set of 12 papers published in Nature journals offers new atlases of brain development and hints at the varied evolutionary origins of different cell types.
By Holly Barker
#neuroskyence
www.thetransmitter.org/spectrum/con...
By Holly Barker
#neuroskyence
www.thetransmitter.org/spectrum/con...
Constellation of studies charts brain development, offers ‘dramatic revision’
The atlases could pinpoint pathways that determine the fate of cells linked to neurodevelopmental conditions.
www.thetransmitter.org
November 5, 2025 at 6:26 PM
A set of 12 papers published in Nature journals offers new atlases of brain development and hints at the varied evolutionary origins of different cell types.
By Holly Barker
#neuroskyence
www.thetransmitter.org/spectrum/con...
By Holly Barker
#neuroskyence
www.thetransmitter.org/spectrum/con...
Reposted by Matteo Guardamagna
🚨Job alert🚨
The lab has up to *3 postdoc openings* for comp systems neuroscientists interested in describing and manipulating neural population dynamics mediating behaviour
This is part of a collaborative ARIA grant "4D precision control of cortical dynamics"
euraxess.ec.europa.eu/jobs/383909
The lab has up to *3 postdoc openings* for comp systems neuroscientists interested in describing and manipulating neural population dynamics mediating behaviour
This is part of a collaborative ARIA grant "4D precision control of cortical dynamics"
euraxess.ec.europa.eu/jobs/383909
3 Postdoctoral Research Fellows
Champalimaud Foundation (Fundação D. Anna de Sommer Champalimaud e Dr.
euraxess.ec.europa.eu
November 4, 2025 at 5:11 PM
🚨Job alert🚨
The lab has up to *3 postdoc openings* for comp systems neuroscientists interested in describing and manipulating neural population dynamics mediating behaviour
This is part of a collaborative ARIA grant "4D precision control of cortical dynamics"
euraxess.ec.europa.eu/jobs/383909
The lab has up to *3 postdoc openings* for comp systems neuroscientists interested in describing and manipulating neural population dynamics mediating behaviour
This is part of a collaborative ARIA grant "4D precision control of cortical dynamics"
euraxess.ec.europa.eu/jobs/383909
Reposted by Matteo Guardamagna
Proud to have contributed to @gaiabianchini.bsky.social and @flor-iacaruso.bsky.social new paper on how the superior colliculus temporally integrates multisensory information
Functional specialisation of multisensory temporal integration in the mouse superior colliculus - Nature Communications
Whether and how anatomically distinct regions of the superior colliculus (SC) exhibit specialisation in multisensory temporal integration to facilitate different behavioural responses are not fully un...
www.nature.com
November 3, 2025 at 9:17 AM
Proud to have contributed to @gaiabianchini.bsky.social and @flor-iacaruso.bsky.social new paper on how the superior colliculus temporally integrates multisensory information
Reposted by Matteo Guardamagna
What did Pasolini know? Fifty years after his brutal murder, the director’s vision of fascism is more urgent than ever
What did Pasolini know? Fifty years after his brutal murder, the director’s vision of fascism is more urgent than ever
With mystery still surrounding Pier Paolo Pasolini’s death, the poet and film-maker’s warnings of corruption and rising totalitarianism offer a chilling message for our times
www.theguardian.com
November 1, 2025 at 10:04 AM
What did Pasolini know? Fifty years after his brutal murder, the director’s vision of fascism is more urgent than ever
Reposted by Matteo Guardamagna
Thrilled that our paper is out today in Nature!
www.nature.com/articles/s4...
www.nature.com/articles/s4...
Sensory expectations shape neural population dynamics in motor circuits
Nature - Experiments with human volunteers and macaques show that expectations produced by probabilistic cueing of future sensory inputs shape motor circuit dynamics in order to increase the...
www.nature.com
October 29, 2025 at 4:11 PM
Thrilled that our paper is out today in Nature!
www.nature.com/articles/s4...
www.nature.com/articles/s4...
Reposted by Matteo Guardamagna
My co-authors have yet to move to Bluesky, so I'm pleased to announce our latest work has just been published in @nature.com Neuroscience. Amazing work led by Junheng Li, revealing that falling asleep follows a predictable bifurcation pattern #neuroskyence #sleep
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Falling asleep follows a predictable bifurcation dynamic - Nature Neuroscience
Li et al. propose a conceptual framework to study the phenomenon of falling asleep based on electroencephalogram data. They show that a tipping point marks the brain’s nonlinear wake-to-sleep transiti...
www.nature.com
October 28, 2025 at 5:35 PM
My co-authors have yet to move to Bluesky, so I'm pleased to announce our latest work has just been published in @nature.com Neuroscience. Amazing work led by Junheng Li, revealing that falling asleep follows a predictable bifurcation pattern #neuroskyence #sleep
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Matteo Guardamagna
Various theoretical properties derived for gamma oscillations based on canonical E-SOM-PV microcircuit connectivity using mean-field modelling, which moves beyond classic Wilson-Cowan models in important ways
biorxiv.org/content/10.1... - w. Farzin Tahvili & Matteo Di Volo
biorxiv.org/content/10.1... - w. Farzin Tahvili & Matteo Di Volo
A mean-field model of neural networks with PV and SOM interneurons reveals connectivity-based mechanisms of gamma oscillations
Classic theoretical models of cortical oscillations are based on the interactions between two populations of excitatory and inhibitory neurons. Nevertheless, experimental studies and network simulatio...
biorxiv.org
October 24, 2025 at 11:02 AM
Various theoretical properties derived for gamma oscillations based on canonical E-SOM-PV microcircuit connectivity using mean-field modelling, which moves beyond classic Wilson-Cowan models in important ways
biorxiv.org/content/10.1... - w. Farzin Tahvili & Matteo Di Volo
biorxiv.org/content/10.1... - w. Farzin Tahvili & Matteo Di Volo
Reposted by Matteo Guardamagna
We are hiring 🎉 Brandeis Neuroscience is looking for an Assistant Professor. The search is in the broad area of cellular/circuit neuroscience. It’s a fantastic place to do research and train students.If you’re interested, apply and reach out with any questions!
academicjobsonline.org/ajo/jobs/30961
academicjobsonline.org/ajo/jobs/30961
Brandeis University, Biology Department
Job #AJO30961, Assistant Professor in Biology and Neuroscience Program, Biology Department, Brandeis University, Waltham, Massachusetts, US
academicjobsonline.org
October 22, 2025 at 11:57 PM
We are hiring 🎉 Brandeis Neuroscience is looking for an Assistant Professor. The search is in the broad area of cellular/circuit neuroscience. It’s a fantastic place to do research and train students.If you’re interested, apply and reach out with any questions!
academicjobsonline.org/ajo/jobs/30961
academicjobsonline.org/ajo/jobs/30961
Reposted by Matteo Guardamagna
Out today in Nature: We uncover a neural mechanism for the integration of two internal states - hunger and estrous state - and how this integration shapes pup-directed behaviors in mice.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Integration of hunger and hormonal state gates infant-directed aggression - Nature
Combined behavioural, circuit-level and cellular approaches are used to demonstrate how hypothalamic neurons integrate hunger and oestrous state to drive a switch in how female mice interact with pups...
www.nature.com
October 22, 2025 at 3:30 PM
Out today in Nature: We uncover a neural mechanism for the integration of two internal states - hunger and estrous state - and how this integration shapes pup-directed behaviors in mice.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Matteo Guardamagna
𝗘𝗻𝗱 𝗼𝗳 𝘁𝗵𝗲 𝗲𝗺𝗽𝗶𝗿𝗲 𝗼𝗳 𝗻𝗲𝘂𝗿𝗼𝗻𝘀 𝗶𝗻 𝘁𝗵𝗲 𝗯𝗿𝗮𝗶𝗻??
Astrocytes in the regulation of fear memories!
www.nature.com/articles/s41...
#neuroskyence
h/t @claeneuro.bsky.social
Astrocytes in the regulation of fear memories!
www.nature.com/articles/s41...
#neuroskyence
h/t @claeneuro.bsky.social
The astrocytic ensemble acts as a multiday trace to stabilize memory - Nature
Emotional experience evokes signalling in astrocytes, which form an ensemble that is reinforced by secondary astrocytic state changes resulting from repeated experience, leading to memory stabilizatio...
www.nature.com
October 21, 2025 at 5:57 PM
𝗘𝗻𝗱 𝗼𝗳 𝘁𝗵𝗲 𝗲𝗺𝗽𝗶𝗿𝗲 𝗼𝗳 𝗻𝗲𝘂𝗿𝗼𝗻𝘀 𝗶𝗻 𝘁𝗵𝗲 𝗯𝗿𝗮𝗶𝗻??
Astrocytes in the regulation of fear memories!
www.nature.com/articles/s41...
#neuroskyence
h/t @claeneuro.bsky.social
Astrocytes in the regulation of fear memories!
www.nature.com/articles/s41...
#neuroskyence
h/t @claeneuro.bsky.social
Reposted by Matteo Guardamagna
New essay in @currentbiology.bsky.social special brain-body issue! Fly lab meets psychiatrist: how bodily signals shape cognition and mental health. Great collaboration with Albino Oliveira-Maia showing @champalimaudf.bsky.social discovery ↔️ clinic at its best. www.cell.com/current-biol...
From cognition in the body to the body in cognition
Carlos Ribeiro and Albino Oliveira-Maia propose how brain–body interactions may inform
the study of ‘higher’ cognitive functions such as learning and memory across model
systems.
www.cell.com
October 20, 2025 at 4:40 PM
New essay in @currentbiology.bsky.social special brain-body issue! Fly lab meets psychiatrist: how bodily signals shape cognition and mental health. Great collaboration with Albino Oliveira-Maia showing @champalimaudf.bsky.social discovery ↔️ clinic at its best. www.cell.com/current-biol...
Reposted by Matteo Guardamagna
Really excited to share this Opinion piece we've been working on with fellow head-direction cell geeks @apeyrache.bsky.social @desdemonafricker.bsky.social and (bsky-less?) Andrea Burgalossi! While head-direction cells pop up in many cortical regions, we think that one of them is quite unique (1/8)
The postsubiculum as a head-direction cortex
The organisation of thalamocortical networks follows a conserved structure. Traditionally, these are divided into primary sensory systems that receive…
www.sciencedirect.com
October 15, 2025 at 8:10 PM
Really excited to share this Opinion piece we've been working on with fellow head-direction cell geeks @apeyrache.bsky.social @desdemonafricker.bsky.social and (bsky-less?) Andrea Burgalossi! While head-direction cells pop up in many cortical regions, we think that one of them is quite unique (1/8)
Reposted by Matteo Guardamagna
I am excited to share my PhD work on head-direction cells recorded in the wild, now published in @science.org, where we recorded neurons in bats flying outdoors on an island.
doi.org/10.1126/sci...
With @ray-neuro.bsky.social, Shir Maimon, Liora Las, Nachum Ulanovsky and many others
doi.org/10.1126/sci...
With @ray-neuro.bsky.social, Shir Maimon, Liora Las, Nachum Ulanovsky and many others
October 16, 2025 at 6:04 PM
I am excited to share my PhD work on head-direction cells recorded in the wild, now published in @science.org, where we recorded neurons in bats flying outdoors on an island.
doi.org/10.1126/sci...
With @ray-neuro.bsky.social, Shir Maimon, Liora Las, Nachum Ulanovsky and many others
doi.org/10.1126/sci...
With @ray-neuro.bsky.social, Shir Maimon, Liora Las, Nachum Ulanovsky and many others
Reposted by Matteo Guardamagna
The work with bats on barren, 7-acre Latham Island was Nachum Ulanovsky’s most complex undertaking yet.
By @claudia-lopez.bsky.social
#neuroskyence
www.thetransmitter.org/neuroetholog...
By @claudia-lopez.bsky.social
#neuroskyence
www.thetransmitter.org/neuroetholog...
October 16, 2025 at 6:15 PM
The work with bats on barren, 7-acre Latham Island was Nachum Ulanovsky’s most complex undertaking yet.
By @claudia-lopez.bsky.social
#neuroskyence
www.thetransmitter.org/neuroetholog...
By @claudia-lopez.bsky.social
#neuroskyence
www.thetransmitter.org/neuroetholog...
Reposted by Matteo Guardamagna
Reposted by Matteo Guardamagna
New findings solve “developmental biology’s most complicated problem”: how each olfactory neuron in the ant expresses exactly one out of hundreds of olfactory receptors.
By @vcallier.bsky.social
#neuroskyence
www.thetransmitter.org/sensory-perc...
By @vcallier.bsky.social
#neuroskyence
www.thetransmitter.org/sensory-perc...
October 14, 2025 at 3:34 PM
New findings solve “developmental biology’s most complicated problem”: how each olfactory neuron in the ant expresses exactly one out of hundreds of olfactory receptors.
By @vcallier.bsky.social
#neuroskyence
www.thetransmitter.org/sensory-perc...
By @vcallier.bsky.social
#neuroskyence
www.thetransmitter.org/sensory-perc...
Reposted by Matteo Guardamagna
For those interested in methods for analyzing a specific frequency of neural activity as a series of discrete events, the CBASS code is posted here with an excellent wiki by @q-perrenoud.bsky.social: github.com/cardin-higle...
October 10, 2025 at 1:59 PM
For those interested in methods for analyzing a specific frequency of neural activity as a series of discrete events, the CBASS code is posted here with an excellent wiki by @q-perrenoud.bsky.social: github.com/cardin-higle...
Reposted by Matteo Guardamagna
🚨Big news!🚨
The lab is relocating to Lisbon, joining a great team of experimental and theoretical neuroscientists, and the Neurotechnology Warehouse, a new initiative to bridge basic and translational research.
I'll be sharing postdoc openings soon. Come join us in this new incarnation of the lab!
The lab is relocating to Lisbon, joining a great team of experimental and theoretical neuroscientists, and the Neurotechnology Warehouse, a new initiative to bridge basic and translational research.
I'll be sharing postdoc openings soon. Come join us in this new incarnation of the lab!
🧠🎼 What does it take to restore movement? Neuroscientist and engineer, @juangallego.bsky.social, joins the new Centre for Restorative Neurotechnology at the Champalimaud Foundation.
🔗 Find out more in this interview: www.fchampalimaud.org/news/juan-al...
🔗 Find out more in this interview: www.fchampalimaud.org/news/juan-al...
October 7, 2025 at 4:37 PM
🚨Big news!🚨
The lab is relocating to Lisbon, joining a great team of experimental and theoretical neuroscientists, and the Neurotechnology Warehouse, a new initiative to bridge basic and translational research.
I'll be sharing postdoc openings soon. Come join us in this new incarnation of the lab!
The lab is relocating to Lisbon, joining a great team of experimental and theoretical neuroscientists, and the Neurotechnology Warehouse, a new initiative to bridge basic and translational research.
I'll be sharing postdoc openings soon. Come join us in this new incarnation of the lab!
Reposted by Matteo Guardamagna
Stats on #bodybrain #neuroskyence data can become non-trivial pretty quickly: Anything beyond t-tests on 'systole vs diastole' or 'insp vs exp' will include some form of phase binning, so we need adequate surrogates for robust permutation stats. Plus, these are not available for circular data.
October 9, 2025 at 8:02 AM
Stats on #bodybrain #neuroskyence data can become non-trivial pretty quickly: Anything beyond t-tests on 'systole vs diastole' or 'insp vs exp' will include some form of phase binning, so we need adequate surrogates for robust permutation stats. Plus, these are not available for circular data.
Reposted by Matteo Guardamagna
Finally out: our recent work with Nick Betley is a view into how the brain reshapes its behavior in the face of competing survival needs- and also a potential angle on treatment targets for enduring pain.
A brief rundown...
www.nature.com/articles/s41...
A brief rundown...
www.nature.com/articles/s41...
A parabrachial hub for need-state control of enduring pain - Nature
Activity in a set of parabranchial neurons in the mouse brain is increased during chronic pain, predicts coping behaviour, and can be modulated by circuits activated by survival threats.
www.nature.com
October 9, 2025 at 1:15 PM
Finally out: our recent work with Nick Betley is a view into how the brain reshapes its behavior in the face of competing survival needs- and also a potential angle on treatment targets for enduring pain.
A brief rundown...
www.nature.com/articles/s41...
A brief rundown...
www.nature.com/articles/s41...
How does the brain's spatial navigation system develop? I had so many fun discussions with the incredible communities at Johns Hopkins and Columbia this past week - a lot of exciting ideas for experimental and theoretical work ahead.
Grateful to be hosted by @kavlifoundation.org @lorenzoposani.com
Grateful to be hosted by @kavlifoundation.org @lorenzoposani.com
October 9, 2025 at 7:01 PM
How does the brain's spatial navigation system develop? I had so many fun discussions with the incredible communities at Johns Hopkins and Columbia this past week - a lot of exciting ideas for experimental and theoretical work ahead.
Grateful to be hosted by @kavlifoundation.org @lorenzoposani.com
Grateful to be hosted by @kavlifoundation.org @lorenzoposani.com
Reposted by Matteo Guardamagna
Come do a postdoc at the Wu Tsai Institute!
WTI fellows have freedom to work with anyone at the institute, and preference is given to applicants who want to work on interdisciplinary projects with multiple faculty mentors.
If you’re interested to work with me, please reach out!
WTI fellows have freedom to work with anyone at the institute, and preference is given to applicants who want to work on interdisciplinary projects with multiple faculty mentors.
If you’re interested to work with me, please reach out!
📣 Calling experimental, computational, or theoretical researchers!
WTI's Postdoc Fellowships application is now open, offering a competitive salary, structured mentorship, world-class facilities + more: wti.yale.edu/initiatives/...
Apply by November 10: apply.interfolio.com/174525
#KnowTogether
WTI's Postdoc Fellowships application is now open, offering a competitive salary, structured mentorship, world-class facilities + more: wti.yale.edu/initiatives/...
Apply by November 10: apply.interfolio.com/174525
#KnowTogether
October 8, 2025 at 12:50 PM
Come do a postdoc at the Wu Tsai Institute!
WTI fellows have freedom to work with anyone at the institute, and preference is given to applicants who want to work on interdisciplinary projects with multiple faculty mentors.
If you’re interested to work with me, please reach out!
WTI fellows have freedom to work with anyone at the institute, and preference is given to applicants who want to work on interdisciplinary projects with multiple faculty mentors.
If you’re interested to work with me, please reach out!
Reposted by Matteo Guardamagna
How prediction error drives memory updating: role of locus coeruleus–hippocampal interactions: Trends in Neurosciences www.cell.com/trends/neuro...
How prediction error drives memory updating: role of locus coeruleus–hippocampal interactions
The brain constantly generates predictions based on one’s knowledge of the world,
as captured in memory. When these predictions are in error, our knowledge base must
be revised to remain relevant. Her...
www.cell.com
October 4, 2025 at 3:17 PM
How prediction error drives memory updating: role of locus coeruleus–hippocampal interactions: Trends in Neurosciences www.cell.com/trends/neuro...
Reposted by Matteo Guardamagna
I’m pleased to share our new paper, “Hippocampal ripple diversity organizes neuronal reactivation dynamics in the offline brain”, out in @cp-neuron.bsky.social !
With @vitorlds.bsky.social and David Dupret, we show that diversity in ripple current profiles shapes reactivation dynamics
With @vitorlds.bsky.social and David Dupret, we show that diversity in ripple current profiles shapes reactivation dynamics
October 2, 2025 at 3:46 PM
I’m pleased to share our new paper, “Hippocampal ripple diversity organizes neuronal reactivation dynamics in the offline brain”, out in @cp-neuron.bsky.social !
With @vitorlds.bsky.social and David Dupret, we show that diversity in ripple current profiles shapes reactivation dynamics
With @vitorlds.bsky.social and David Dupret, we show that diversity in ripple current profiles shapes reactivation dynamics
Reposted by Matteo Guardamagna
We have lost an eminent scientist, Jane Goodall, - do not forget her beautiful work and strong voice: - «hope and action: - value and respect animals and protect them and their habitats»
The naturalist Jane Goodall died today at 91. Hope, she argued, is not merely “passive wishful thinking” but a “crucial survival trait.” Revisit a conversation with Goodall, from 2021: nyer.cm/F55JtsS
October 2, 2025 at 2:27 AM
We have lost an eminent scientist, Jane Goodall, - do not forget her beautiful work and strong voice: - «hope and action: - value and respect animals and protect them and their habitats»