Malvina Pizzuto
@malvinapiz.bsky.social
Women Scientist, passionate about lipids, mitochondria and cardiolipin regulation of the immune system. #womeninscience #EDIadvocate
Reposted by Malvina Pizzuto
Check out our new publication, a collaboration with Giovanni Luchetti and Vishva Dixit @ Genentech.
We show that the E.coli effector NleL inhibits intestinal epithelial cell extrusion after #inflammasome activation via degrading the kinases ROCK1 and 2!!
www.nature.com/articles/s41...
Explainer 1/8
We show that the E.coli effector NleL inhibits intestinal epithelial cell extrusion after #inflammasome activation via degrading the kinases ROCK1 and 2!!
www.nature.com/articles/s41...
Explainer 1/8
Enteropathogenic bacteria evade ROCK-driven epithelial cell extrusion - Nature
The bacterial ubiquitin ligase NleL evades host defence mechanisms both by inhibiting pyroptosis and by preventing infected intestinal epithelial cells from being extruded into the lumen and expelled ...
www.nature.com
October 22, 2025 at 3:47 PM
Check out our new publication, a collaboration with Giovanni Luchetti and Vishva Dixit @ Genentech.
We show that the E.coli effector NleL inhibits intestinal epithelial cell extrusion after #inflammasome activation via degrading the kinases ROCK1 and 2!!
www.nature.com/articles/s41...
Explainer 1/8
We show that the E.coli effector NleL inhibits intestinal epithelial cell extrusion after #inflammasome activation via degrading the kinases ROCK1 and 2!!
www.nature.com/articles/s41...
Explainer 1/8
Reposted by Malvina Pizzuto
#InflammaZoom free Webinar is back on Monday October 20th! With James Murphy (WEHI, Melbourne, Australia) @pseudokinase.bsky.social and Jonathan Maelfait (VIB-UGent, Ghent, Belgium)
Register now: bit.ly/4iXGqjw
Register now: bit.ly/4iXGqjw
October 17, 2025 at 6:29 AM
#InflammaZoom free Webinar is back on Monday October 20th! With James Murphy (WEHI, Melbourne, Australia) @pseudokinase.bsky.social and Jonathan Maelfait (VIB-UGent, Ghent, Belgium)
Register now: bit.ly/4iXGqjw
Register now: bit.ly/4iXGqjw
Reposted by Malvina Pizzuto
📌 Save the Date - #EUResearchersNight returns on Friday 26/09!
Join us across Europe for a night full of science, discovery & fun - connecting curious minds with brilliant researchers, including ERC grantees and their teams💡!
📍Find events near you: link.europa.eu/TbHmPP 🧪
Join us across Europe for a night full of science, discovery & fun - connecting curious minds with brilliant researchers, including ERC grantees and their teams💡!
📍Find events near you: link.europa.eu/TbHmPP 🧪
September 19, 2025 at 10:21 AM
📌 Save the Date - #EUResearchersNight returns on Friday 26/09!
Join us across Europe for a night full of science, discovery & fun - connecting curious minds with brilliant researchers, including ERC grantees and their teams💡!
📍Find events near you: link.europa.eu/TbHmPP 🧪
Join us across Europe for a night full of science, discovery & fun - connecting curious minds with brilliant researchers, including ERC grantees and their teams💡!
📍Find events near you: link.europa.eu/TbHmPP 🧪
Reposted by Malvina Pizzuto
Very cool talk today at #CABDseminars by Malvina Pizzuto. Dr. Pizzuto explained the work assessing cardiolipin control over inflammatory pathways and immune dysfunctions. Malvina was invited by Peter Askjaer. Thanks for coming @malvinapiz.bsky.social
September 19, 2025 at 2:57 PM
Very cool talk today at #CABDseminars by Malvina Pizzuto. Dr. Pizzuto explained the work assessing cardiolipin control over inflammatory pathways and immune dysfunctions. Malvina was invited by Peter Askjaer. Thanks for coming @malvinapiz.bsky.social
Reposted by Malvina Pizzuto
✅Ha venido la doctora Malvina Pizzuto, a hablarnos de "Evaluación del control de la cardiolipina sobre las vías inflamatorias en situaciones de enfermedad como el shock séptico". 🦠
@ipblncsic.bsky.social
@csic.es
@csicandalextrem.bsky.social
@universitypress.cambridge.org
@malvinapiz.bsky.social
@ipblncsic.bsky.social
@csic.es
@csicandalextrem.bsky.social
@universitypress.cambridge.org
@malvinapiz.bsky.social
September 17, 2025 at 11:47 AM
✅Ha venido la doctora Malvina Pizzuto, a hablarnos de "Evaluación del control de la cardiolipina sobre las vías inflamatorias en situaciones de enfermedad como el shock séptico". 🦠
@ipblncsic.bsky.social
@csic.es
@csicandalextrem.bsky.social
@universitypress.cambridge.org
@malvinapiz.bsky.social
@ipblncsic.bsky.social
@csic.es
@csicandalextrem.bsky.social
@universitypress.cambridge.org
@malvinapiz.bsky.social
Reposted by Malvina Pizzuto
#CABDseminars
"Assessing Cardiolipin Control Over Inflammatory Pathways and Immune Dysfunctions" by Malvina Pizzuto @malvinapiz.bsky.social, University of Cambridge (UK)
🗓️ September 19 th
⏰ 12 pm
📍Rosalind Franklin Auditorium at the CABD
Hosted by Peter Askjaer
"Assessing Cardiolipin Control Over Inflammatory Pathways and Immune Dysfunctions" by Malvina Pizzuto @malvinapiz.bsky.social, University of Cambridge (UK)
🗓️ September 19 th
⏰ 12 pm
📍Rosalind Franklin Auditorium at the CABD
Hosted by Peter Askjaer
September 17, 2025 at 8:45 AM
#CABDseminars
"Assessing Cardiolipin Control Over Inflammatory Pathways and Immune Dysfunctions" by Malvina Pizzuto @malvinapiz.bsky.social, University of Cambridge (UK)
🗓️ September 19 th
⏰ 12 pm
📍Rosalind Franklin Auditorium at the CABD
Hosted by Peter Askjaer
"Assessing Cardiolipin Control Over Inflammatory Pathways and Immune Dysfunctions" by Malvina Pizzuto @malvinapiz.bsky.social, University of Cambridge (UK)
🗓️ September 19 th
⏰ 12 pm
📍Rosalind Franklin Auditorium at the CABD
Hosted by Peter Askjaer
Still wrapping my head around the fact that it’s finally out!! 🎉 From hypothesis in 2017 to data in 2020, it took 5 more years to fully prove the story. Long road for a lipid inhibitor, but worth it. Wonder how long a Nature paper takes… maybe I’ll find out soon! 😉 #ResearchLife
August 4, 2025 at 3:08 PM
Still wrapping my head around the fact that it’s finally out!! 🎉 From hypothesis in 2017 to data in 2020, it took 5 more years to fully prove the story. Long road for a lipid inhibitor, but worth it. Wonder how long a Nature paper takes… maybe I’ll find out soon! 😉 #ResearchLife
🚨It’s out @embojournal.org 🚨
Cardiolipin inhibits Caspase-4/11!
Huge thanks to my brilliant supervisors Kate & Pablo, to @s-burgener.bsky.social & Mercedes and all the @inflammasomelab.bsky.social, it was a joy working and laughing with you, and to @brozlab.bsky.social & Si Ming lab.
Cardiolipin inhibits Caspase-4/11!
Huge thanks to my brilliant supervisors Kate & Pablo, to @s-burgener.bsky.social & Mercedes and all the @inflammasomelab.bsky.social, it was a joy working and laughing with you, and to @brozlab.bsky.social & Si Ming lab.
July 23, 2025 at 11:23 AM
🚨It’s out @embojournal.org 🚨
Cardiolipin inhibits Caspase-4/11!
Huge thanks to my brilliant supervisors Kate & Pablo, to @s-burgener.bsky.social & Mercedes and all the @inflammasomelab.bsky.social, it was a joy working and laughing with you, and to @brozlab.bsky.social & Si Ming lab.
Cardiolipin inhibits Caspase-4/11!
Huge thanks to my brilliant supervisors Kate & Pablo, to @s-burgener.bsky.social & Mercedes and all the @inflammasomelab.bsky.social, it was a joy working and laughing with you, and to @brozlab.bsky.social & Si Ming lab.
Reposted by Malvina Pizzuto
(1/3) 🏆 Applications are now open for the 2025 ACDS Professional Development Award!
A $2,000 grant for a PhD student or ECR to support national or international professional development 🌍✈️
Conference? Lab visit? Data training? This one's for you.
More info below
A $2,000 grant for a PhD student or ECR to support national or international professional development 🌍✈️
Conference? Lab visit? Data training? This one's for you.
More info below
#celldeathresearch #careerdevelopment | Australasian Cell Death Society (ACDS)
🥇2025 ACDS Professional Development Award 🥇
Applications are now open!
Are you a PhD student or early-career researcher in the cell death field? Don’t miss your chance to apply for our $2,000 travel ...
www.linkedin.com
May 5, 2025 at 1:01 AM
(1/3) 🏆 Applications are now open for the 2025 ACDS Professional Development Award!
A $2,000 grant for a PhD student or ECR to support national or international professional development 🌍✈️
Conference? Lab visit? Data training? This one's for you.
More info below
A $2,000 grant for a PhD student or ECR to support national or international professional development 🌍✈️
Conference? Lab visit? Data training? This one's for you.
More info below
Streaming tomorrow morning in Europe! Don't miss it
(1/3) 🌍 We're kicking off our 2025 International Cell Death Seminar Series with @ecdo & @CDDpress on Wed 7 May!
🕓 4:30pm AEST / 8:30am CEST
📍 Online (Zoom link in poster)
A fantastic international line-up awaits... 🧵👇
🕓 4:30pm AEST / 8:30am CEST
📍 Online (Zoom link in poster)
A fantastic international line-up awaits... 🧵👇
May 6, 2025 at 9:07 PM
Streaming tomorrow morning in Europe! Don't miss it
The last three weeks before leaving my current lab 😅 you are never done with experiments!
December 18, 2024 at 1:26 PM
The last three weeks before leaving my current lab 😅 you are never done with experiments!
Reposted by Malvina Pizzuto
My 1st post in bluesky goes for🚨phagocyte lovers🚨
send ABSTRACT & REGISTER NOW!!!
phagocytes2025.com
📌Madrid @CNIC_CARDIO
📆 26-28 March '25
20 🔝🌍speakers
28 short talks + posters
Support by
www.inmunologia.org
www.embo.org
CRC_TRR332 & TRR359_PILOT
Travel bursaries by www.efis.org & EurJImmunol
send ABSTRACT & REGISTER NOW!!!
phagocytes2025.com
📌Madrid @CNIC_CARDIO
📆 26-28 March '25
20 🔝🌍speakers
28 short talks + posters
Support by
www.inmunologia.org
www.embo.org
CRC_TRR332 & TRR359_PILOT
Travel bursaries by www.efis.org & EurJImmunol
November 29, 2024 at 6:33 PM
My 1st post in bluesky goes for🚨phagocyte lovers🚨
send ABSTRACT & REGISTER NOW!!!
phagocytes2025.com
📌Madrid @CNIC_CARDIO
📆 26-28 March '25
20 🔝🌍speakers
28 short talks + posters
Support by
www.inmunologia.org
www.embo.org
CRC_TRR332 & TRR359_PILOT
Travel bursaries by www.efis.org & EurJImmunol
send ABSTRACT & REGISTER NOW!!!
phagocytes2025.com
📌Madrid @CNIC_CARDIO
📆 26-28 March '25
20 🔝🌍speakers
28 short talks + posters
Support by
www.inmunologia.org
www.embo.org
CRC_TRR332 & TRR359_PILOT
Travel bursaries by www.efis.org & EurJImmunol
Reposted by Malvina Pizzuto
#NoTimeToDie! @inflammasomelab, Holley, Monteleone &co show @natimmunol.bsky.social that cells that die by #pyroptosis, or #necroptosis, are crowned with F-actin filopodia that makes them visible by dendritic cells via CLEC9A to initiate adaptive immunity! www.nature.com/articles/s41...
Pyroptotic cell corpses are crowned with F-actin-rich filopodia that engage CLEC9A signaling in incoming dendritic cells - Nature Immunology
Pyroptotic cell death results in inflammation. Here the authors find that F-actin-rich structures formed during macrophage pyroptosis persist after cell death to activate dendritic cells.
www.nature.com
December 5, 2024 at 4:55 PM
#NoTimeToDie! @inflammasomelab, Holley, Monteleone &co show @natimmunol.bsky.social that cells that die by #pyroptosis, or #necroptosis, are crowned with F-actin filopodia that makes them visible by dendritic cells via CLEC9A to initiate adaptive immunity! www.nature.com/articles/s41...
Reposted by Malvina Pizzuto
Imagine cells bursting into tiny fireworks to alert the immune system and spark a powerful defense.
@carolinelholley.bsky.social @inflammasomelab.bsky.social @jkagan.bsky.social @samstehbens.bsky.social
@doktrnick.bsky.social
t.co/dE9wPARavh
#ImmunoSky 🧪
@carolinelholley.bsky.social @inflammasomelab.bsky.social @jkagan.bsky.social @samstehbens.bsky.social
@doktrnick.bsky.social
t.co/dE9wPARavh
#ImmunoSky 🧪
December 11, 2024 at 10:24 AM
Imagine cells bursting into tiny fireworks to alert the immune system and spark a powerful defense.
@carolinelholley.bsky.social @inflammasomelab.bsky.social @jkagan.bsky.social @samstehbens.bsky.social
@doktrnick.bsky.social
t.co/dE9wPARavh
#ImmunoSky 🧪
@carolinelholley.bsky.social @inflammasomelab.bsky.social @jkagan.bsky.social @samstehbens.bsky.social
@doktrnick.bsky.social
t.co/dE9wPARavh
#ImmunoSky 🧪
Reposted by Malvina Pizzuto
How do macrophages sense SARS-CoV-2 infection to drive inflammation (protective or disease causing) in COVID-19? Our 2023 paper in Science Signalling helps explain 🧵
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Macrophage ACE2 is necessary for SARS-CoV-2 replication and subsequent cytokine responses that restrict continued virion release
ACE2 in macrophages promotes infection that enables an intrinsic antiviral response to SARS-CoV-2.
www.science.org
November 11, 2024 at 6:32 AM
How do macrophages sense SARS-CoV-2 infection to drive inflammation (protective or disease causing) in COVID-19? Our 2023 paper in Science Signalling helps explain 🧵
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Grateful to be part of the amazing team behind our student and postdoc associations @SIMBAatUQ @EMCRA_IMB @IMBatUQ. We've worked hard to support our community. I'm also honored to receive recognition for my contribution. Still so much to do, best of luck to next year’s committees
December 9, 2024 at 9:51 AM
Grateful to be part of the amazing team behind our student and postdoc associations @SIMBAatUQ @EMCRA_IMB @IMBatUQ. We've worked hard to support our community. I'm also honored to receive recognition for my contribution. Still so much to do, best of luck to next year’s committees
Reposted by Malvina Pizzuto
Have you ever wondered whether pyroptotic corpses have functions beyond the grave? We made the surprising discovery that pyroptotic corpses are flagged by #filopodia to alert #DendriticCells they need autopsy. A short Bluetorial (1/13)👇with movies!
Link: rdcu.be/d2mjm
Link: rdcu.be/d2mjm
Pyroptotic cell corpses are crowned with F-actin-rich filopodia that engage CLEC9A signaling in incoming dendritic cells
Nature Immunology - Pyroptotic cell death results in inflammation. Here the authors find that F-actin-rich structures formed during macrophage pyroptosis persist after cell death to activate...
rdcu.be
December 9, 2024 at 1:39 AM
Have you ever wondered whether pyroptotic corpses have functions beyond the grave? We made the surprising discovery that pyroptotic corpses are flagged by #filopodia to alert #DendriticCells they need autopsy. A short Bluetorial (1/13)👇with movies!
Link: rdcu.be/d2mjm
Link: rdcu.be/d2mjm
Reposted by Malvina Pizzuto
Hi all! My name is Cornelius, and I'm an assistant professor in the Department of Biochemistry and Biophysics @pennmedicine.bsky.social @upenn.bsky.social. My lab is interested in host-pathogen interactions with a focus on how the host responds to infections. I'm passionate about mentoring, too!
November 18, 2024 at 4:09 AM
Hi all! My name is Cornelius, and I'm an assistant professor in the Department of Biochemistry and Biophysics @pennmedicine.bsky.social @upenn.bsky.social. My lab is interested in host-pathogen interactions with a focus on how the host responds to infections. I'm passionate about mentoring, too!
Hi all, my name is Malvina. I am a senior postdoctoral researcher trying my best to start my lab and study the regulation of the immune system by cardiolipin and mitochondria. I am passionate about #inflammasome #caspases and #mitochondria, and I advocate #equity #diversity and #inclusion in science
November 18, 2024 at 7:37 AM
Hi all, my name is Malvina. I am a senior postdoctoral researcher trying my best to start my lab and study the regulation of the immune system by cardiolipin and mitochondria. I am passionate about #inflammasome #caspases and #mitochondria, and I advocate #equity #diversity and #inclusion in science