Licheng Zou
lichengzou.bsky.social
Licheng Zou
@lichengzou.bsky.social
Theoretical neuroscience doctoral researcher from Fred Wolf's group at MPI-DS/ MSc from U. Amsterdam/ BSc from SJTU
Web: https://lichengzou0509.github.io/Academic-CV/
Reposted by Licheng Zou
Great new paper by my colleagues Gloria & Alex, and @lichengzou.bsky.social. Hebbian plasticity accounts for much of representational drift: Drift is ongoing memory storage, not noise. Also reconciles contradictory findings on stability after repeated exposure.

www.nature.com/articles/s41...
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Representational drift as the consequence of ongoing memory storage - Scientific Reports
Scientific Reports - Representational drift as the consequence of ongoing memory storage
www.nature.com
August 1, 2025 at 9:56 AM
Reposted by Licheng Zou
BTSP, but not STDP, can account for place field changes in hippocampus, out in Nature Neuroscience today:

www.nature.com/articles/s41...

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Synaptic plasticity rules driving representational shifting in the hippocampus - Nature Neuroscience
Madar et al. report that behavioral timescale synaptic plasticity (BTSP), not spike-timing-dependent plasticity, explains heterogeneous place fields shifting in the hippocampus. The probability of BTS...
www.nature.com
April 8, 2025 at 12:49 PM
Reposted by Licheng Zou
Please spread the word!! We are accepting applications for the Cold Spring Harbor Asia Computational and Cognitive Summer School in Suzhou, China. Dates: June 29 to July 20 of 2025. Application deadline: March 31. #computationalneuroscience. For the top three reasons to attend, see thread below:
March 18, 2025 at 11:43 AM
Reposted by Licheng Zou
Most neuroscience research is exploratory: they search for *something* rather than testing a hypothesis. It's harking. I used to see that as a problem, but not anymore. The 1st papers generate hypotheses; the real testing comes later. Science only make sense collectively, not individually.
When I read research papers that are the result of very expensive work (experiments or simulations) I always want to know: how could this project have possibly ended with a null result? And is there an argument in this paper that compares the actual result to this null? If not, I'm very suspicious.
March 13, 2025 at 8:14 AM
Reposted by Licheng Zou
Our new preprint: We found that during representational drift co-activation of neuron pairs is predictive of future effective connectivity. Drift is - in parts - just Hebbian plasticity. But we also need a stochastic process to account for our observations.

doi.org/10.1101/2025...
January 6, 2025 at 10:03 AM
Reposted by Licheng Zou
Sometimes I think the most important thing a computational neuroscientist can do to encourage acceptance of their work in the broader experimental community is just to plot their model data in the exact same way the relevant experimental data was plotted. It's very affecting!
November 25, 2024 at 5:53 PM
Reposted by Licheng Zou
𝗧𝗵𝗲 𝗺𝗼𝘀𝘁 𝗯𝗮𝘀𝗶𝗰 𝗶𝗻𝘁𝗿𝗼𝗱𝘂𝗰𝘁𝗶𝗼𝗻 𝘁𝗼 𝗳𝗠𝗥𝗜 𝗻𝗲𝘁𝘄𝗼𝗿𝗸𝘀.

Please, absolutely no equations, think of someone math phobic. Much better if a paper. thanks
#neuroscience
November 25, 2024 at 6:02 PM