Kellie Machlus
@kmachlus.bsky.social
I research hematopoiesis and how megakaryocytes make platelets 🩸🔬
Asst Professor at Harvard Medical School and Boston Children’s Hospital
🏳️🌈 she/her #medsky #scisky #hematology
Asst Professor at Harvard Medical School and Boston Children’s Hospital
🏳️🌈 she/her #medsky #scisky #hematology
Excited for this session! If you’re at #AHA25 today, please join us!
Planning for Day 1 of #AHA25? Join VB.CVS.04: Keep It Simple – Cutting-Edge Vascular, Lipid, and Coagulation Research:
📅 Friday, November 7 | 12:30–1:45 PM
📍 Rivergate – 1st Floor of the Convention Center
⚡️ Fast and focused updates tailored for both researchers and clinicians.
📅 Friday, November 7 | 12:30–1:45 PM
📍 Rivergate – 1st Floor of the Convention Center
⚡️ Fast and focused updates tailored for both researchers and clinicians.
November 7, 2025 at 3:52 PM
Excited for this session! If you’re at #AHA25 today, please join us!
Reposted by Kellie Machlus
A little known - but hugely consequential - part of the government’s changes to science funding:
open.substack.com/pub/sciencea...
open.substack.com/pub/sciencea...
A Quiet Policy Shift That Could Devastate American Science
Why NIH’s sudden move to multi-year grant funding should alarm every principal investigator and university
open.substack.com
July 29, 2025 at 6:06 PM
A little known - but hugely consequential - part of the government’s changes to science funding:
open.substack.com/pub/sciencea...
open.substack.com/pub/sciencea...
So well put. Something I am thinking about every day with research as well.
“I was once so compelled by medicine’s commitment to the worth of each human life that I set out to live by it. Now I know that a doctor’s ability to fulfill this commitment—to live a moral life in medicine—depends on the systems of care that we as a society build.”
www.newyorker.com/news/the-led...
www.newyorker.com/news/the-led...
Sick Children Will Be Among the Victims of Trump’s Big Bill
Cuts to federal health-care spending make it harder for doctors to make the oldest promise in medicine: that we will do no harm.
www.newyorker.com
July 13, 2025 at 4:31 PM
So well put. Something I am thinking about every day with research as well.
This please 👇🏼
This would be a great time for everyone to be cool when reviewing manuscripts and *not* request $25,000 worth of new experiments that don’t substantially advance or validate the study...
June 5, 2025 at 12:35 AM
This please 👇🏼
Now is a the time to get involved in your scientific societies. #Hematology #HemeSky
@ash.hematology.org is stepping up for Hematology - HOW CAN YOU HELP?
If you want to be on a committee nominate yourself or someone else below. I am also happy to nominate you, so just reach out.
Deadline May 31!
@ash.hematology.org is stepping up for Hematology - HOW CAN YOU HELP?
If you want to be on a committee nominate yourself or someone else below. I am also happy to nominate you, so just reach out.
Deadline May 31!
ASH seeks passionate members to shape the future of hematology. Nominate yourself or a colleague for an ASH committee and help drive the Society’s mission forward. Submit today: www.hematology.org/a...
📅 Nominations due: May 31, 2025
#Leadership #Hematology #MedSky #HemeSky
📅 Nominations due: May 31, 2025
#Leadership #Hematology #MedSky #HemeSky
May 15, 2025 at 6:34 PM
Now is a the time to get involved in your scientific societies. #Hematology #HemeSky
@ash.hematology.org is stepping up for Hematology - HOW CAN YOU HELP?
If you want to be on a committee nominate yourself or someone else below. I am also happy to nominate you, so just reach out.
Deadline May 31!
@ash.hematology.org is stepping up for Hematology - HOW CAN YOU HELP?
If you want to be on a committee nominate yourself or someone else below. I am also happy to nominate you, so just reach out.
Deadline May 31!
Oh.
After freezing all grants to Columbia University last week, the National Institutes of Health is now stopping grant and contract payments to Harvard University and four other universities. scim.ag/4ikYp2T
NIH freezes funds to Harvard and four other universities, but can’t tell them
Move follows broader White House attack on Harvard funding and stop-work orders to contractors
scim.ag
April 18, 2025 at 10:48 PM
Oh.
Reposted by Kellie Machlus
The information I am receiving is consistent with the STAT story.
The boards are being purged of women and minoritized scientists with no other obvious pattern. And for the cases where I have some information, the effects are not subtle...Boards going from 35% women to 10% women.
3/n
The boards are being purged of women and minoritized scientists with no other obvious pattern. And for the cases where I have some information, the effects are not subtle...Boards going from 35% women to 10% women.
3/n
March 25, 2025 at 11:01 PM
The information I am receiving is consistent with the STAT story.
The boards are being purged of women and minoritized scientists with no other obvious pattern. And for the cases where I have some information, the effects are not subtle...Boards going from 35% women to 10% women.
3/n
The boards are being purged of women and minoritized scientists with no other obvious pattern. And for the cases where I have some information, the effects are not subtle...Boards going from 35% women to 10% women.
3/n
Reposted by Kellie Machlus
The FDA just cancelled a meeting to select flu strains for next season's flu shots.
"It's unclear what the canceled meeting will mean for Americans who want to get a flu vaccine next season."
www.nbcnews.com/health/healt...
"It's unclear what the canceled meeting will mean for Americans who want to get a flu vaccine next season."
www.nbcnews.com/health/healt...
FDA cancels meeting to select flu strains for next season's shots
The canceled meeting comes just days after a CDC vaccine advisory committee meeting was abruptly postponed.
www.nbcnews.com
February 27, 2025 at 2:01 AM
The FDA just cancelled a meeting to select flu strains for next season's flu shots.
"It's unclear what the canceled meeting will mean for Americans who want to get a flu vaccine next season."
www.nbcnews.com/health/healt...
"It's unclear what the canceled meeting will mean for Americans who want to get a flu vaccine next season."
www.nbcnews.com/health/healt...
Reposted by Kellie Machlus
The City of Boston is leading 40+ mayors, cities, and counties in an amicus brief against the Trump Administration's drastic and illegal cuts to federal research funding—cuts that will lead to immediate job losses nationwide.
February 20, 2025 at 10:17 PM
The City of Boston is leading 40+ mayors, cities, and counties in an amicus brief against the Trump Administration's drastic and illegal cuts to federal research funding—cuts that will lead to immediate job losses nationwide.
Reposted by Kellie Machlus
The Trump administration blocked key parts of the federal government’s apparatus for funding biomedical research, effectively halting progress on much of the country’s future work on illnesses like cancer and addiction despite a federal judge’s order to release grant money.
Trump Administration Stalls Scientific Research Despite Court Ruling
Using an arcane law, officials have effectively delayed funding from the National Institutes of Health, leaving medical studies in jeopardy.
www.nytimes.com
February 22, 2025 at 6:25 AM
The Trump administration blocked key parts of the federal government’s apparatus for funding biomedical research, effectively halting progress on much of the country’s future work on illnesses like cancer and addiction despite a federal judge’s order to release grant money.
Reposted by Kellie Machlus
Ok scientists & those who love science 🧪: here is another exhortation. Call Congress TODAY about the freeze on NIH Council Meetings and Study Sections. Emphasize that this means NO new grants are being funded & labs will soon start to shut down and fire employees. Phone numbers are at:
5calls.org
5calls.org
5 Calls
Spend 5 minutes. Make 5 calls. Make your voice heard.
5calls.org
February 21, 2025 at 5:23 PM
Ok scientists & those who love science 🧪: here is another exhortation. Call Congress TODAY about the freeze on NIH Council Meetings and Study Sections. Emphasize that this means NO new grants are being funded & labs will soon start to shut down and fire employees. Phone numbers are at:
5calls.org
5calls.org
Reposted by Kellie Machlus
Almost all grant-review meetings under Trump 2.0 remain suspended at the US National Institutes of Health (NIH), preventing the world’s largest public funder of biomedical research from spending much of its US$47 billion annual budget.
https://go.nature.com/4gM6oW4
https://go.nature.com/4gM6oW4
Revealed: NIH research grants still frozen despite lawsuits challenging Trump order
The Trump administration is exploiting a loophole to keep a funding freeze in place, leaving researchers in limbo.
go.nature.com
February 20, 2025 at 8:04 PM
Almost all grant-review meetings under Trump 2.0 remain suspended at the US National Institutes of Health (NIH), preventing the world’s largest public funder of biomedical research from spending much of its US$47 billion annual budget.
https://go.nature.com/4gM6oW4
https://go.nature.com/4gM6oW4
Reposted by Kellie Machlus
This is a red alert for US science, for new cures & treatments for diseases that afflict everyone in this country. This isn't "oh, it will blow over." Soon we will have reached the point of no return destroying what it has taken decades to build. WE NEED TO BE BANGING DOWN THE DOORS IN CONGRESS.
If the block on the Federal Register isn’t removed in the next few months, I fear a majority of labs will close within a year. This small procedural wrench has the power to kill US science indefinitely, losing an entire generation of discovery and innovation.
I had two grant proposals up for review in the NIH Bacterial Virulence (BV) study section. It was canceled without notice this morning.
Without those grants, my lab must close within a year.
And so the purge of scientific research in the US continues
🤬
#MicroSky 🦠🧫🧪🧬🔬
Without those grants, my lab must close within a year.
And so the purge of scientific research in the US continues
🤬
#MicroSky 🦠🧫🧪🧬🔬
February 20, 2025 at 3:33 PM
This is a red alert for US science, for new cures & treatments for diseases that afflict everyone in this country. This isn't "oh, it will blow over." Soon we will have reached the point of no return destroying what it has taken decades to build. WE NEED TO BE BANGING DOWN THE DOORS IN CONGRESS.
Study section freeze hits NIH
A freeze on meetings of expert panels that peer review grant proposals at the National Institutes of Health is kicking in this week.
Follow Science’s coverage of President Donald Trump’s impact on U.S. research and science globally. ⬇️ scim.ag/40XtSSi
Follow Science’s coverage of President Donald Trump’s impact on U.S. research and science globally. ⬇️ scim.ag/40XtSSi
Trump Tracker: Firings, lawsuits, and U.S. science in chaos
Follow President Donald Trump’s impact on U.S. research and science globally
scim.ag
February 19, 2025 at 6:34 PM
Study section freeze hits NIH
Reposted by Kellie Machlus
A large portion of grants awarded by the U.S. National Institutes of Health cannot be funded for the foreseeable future because of an indefinite hold on submissions to the Federal Register, according to an email reviewed by The Transmitter.
By @avaskham.bsky.social
bit.ly/3X8ngz8
By @avaskham.bsky.social
bit.ly/3X8ngz8
Federal Register hold makes ‘end run’ around court pause on NIH funding freeze
NIH-related updates to the Federal Register, which are required for the scheduling of study sections and advisory councils, are on hold indefinitely, according to an email reviewed by <i>The Transmitt...
www.thetransmitter.org
February 18, 2025 at 11:23 PM
A large portion of grants awarded by the U.S. National Institutes of Health cannot be funded for the foreseeable future because of an indefinite hold on submissions to the Federal Register, according to an email reviewed by The Transmitter.
By @avaskham.bsky.social
bit.ly/3X8ngz8
By @avaskham.bsky.social
bit.ly/3X8ngz8
Current inspiration as I continue doing my science as a form of protest and resistance. 🧪🩸💪
February 16, 2025 at 1:46 AM
Current inspiration as I continue doing my science as a form of protest and resistance. 🧪🩸💪
Reposted by Kellie Machlus
This is the most relevant article to NIH and research cuts I’ve seen.
Imagine if this was today , how many people would be saying “Why are we studying Gila Monsters and their impact on diabetes ? That’s wasted money !”
globalnews.ca/news/9793403...
Imagine if this was today , how many people would be saying “Why are we studying Gila Monsters and their impact on diabetes ? That’s wasted money !”
globalnews.ca/news/9793403...
How a Canadian scientist and a venomous lizard helped pave the way for Ozempic - National | Globalnews.ca
In 1984, Dr. Daniel Drucker, an endocrinologist from the University of Toronto, discovered a hormone that helped pave the way for popular diabetes drugs such as Ozempic.
globalnews.ca
February 9, 2025 at 9:58 PM
This is the most relevant article to NIH and research cuts I’ve seen.
Imagine if this was today , how many people would be saying “Why are we studying Gila Monsters and their impact on diabetes ? That’s wasted money !”
globalnews.ca/news/9793403...
Imagine if this was today , how many people would be saying “Why are we studying Gila Monsters and their impact on diabetes ? That’s wasted money !”
globalnews.ca/news/9793403...
Reposted by Kellie Machlus
Reposted by Kellie Machlus
There’s no argument that should reassure anyone enough to go back to business as usual, because none of these actions are happening in isolation. The war on US science won’t end with a court order on indirects.
February 9, 2025 at 3:10 PM
There’s no argument that should reassure anyone enough to go back to business as usual, because none of these actions are happening in isolation. The war on US science won’t end with a court order on indirects.
Reposted by Kellie Machlus
Thinking back on all this I better understand the pain I feel to see science under devastating attack here. It’s not just about my livelihood or my university. It’s about my identity. And it’s about a pursuit that I see as standing along with art, literature, and music as among our highest callings.
February 8, 2025 at 9:41 PM
Thinking back on all this I better understand the pain I feel to see science under devastating attack here. It’s not just about my livelihood or my university. It’s about my identity. And it’s about a pursuit that I see as standing along with art, literature, and music as among our highest callings.
Do it. I mean, it worked out pretty well for me ... 🙃🩸🫶
Envision yourself as a member of this team? Come join our group to pursue research at the interface of megakaryocyte biology and translational medicine.
NIH-funded post-doc positions available to study platelet production and the other functions of megakaryocytes.
NIH-funded post-doc positions available to study platelet production and the other functions of megakaryocytes.
February 5, 2025 at 3:56 PM
Do it. I mean, it worked out pretty well for me ... 🙃🩸🫶
This was so much fun to do with @aswolberg.bsky.social and @gbarnesmd.bsky.social - a chat with two great friends 🥰
Isn't that why we love this community? Great science and great people.
Isn't that why we love this community? Great science and great people.
New Pulse episode alert!🎙️
How do you go from mentee to mentor—and then collaborator? 🤝In today's episode, we chat w/@aswolberg.bsky.social & @kmachlus.bsky.social about the power of mentorship, building community, and finding your niche in science. @gbarnesmd.bsky.social
🎧Tune in: bit.ly/3Q3Q6wI
How do you go from mentee to mentor—and then collaborator? 🤝In today's episode, we chat w/@aswolberg.bsky.social & @kmachlus.bsky.social about the power of mentorship, building community, and finding your niche in science. @gbarnesmd.bsky.social
🎧Tune in: bit.ly/3Q3Q6wI
February 4, 2025 at 5:39 PM
This was so much fun to do with @aswolberg.bsky.social and @gbarnesmd.bsky.social - a chat with two great friends 🥰
Isn't that why we love this community? Great science and great people.
Isn't that why we love this community? Great science and great people.
Hi friends. This is hard. Remember, you’re not alone- there are so many of us here that care a lot and aren’t giving up. Don’t stop talking and don’t let them make you hard.
Reach out to someone that needs some encouragement.
We are here ❤️
#sciencesky
Reach out to someone that needs some encouragement.
We are here ❤️
#sciencesky
January 23, 2025 at 1:22 PM
Hi friends. This is hard. Remember, you’re not alone- there are so many of us here that care a lot and aren’t giving up. Don’t stop talking and don’t let them make you hard.
Reach out to someone that needs some encouragement.
We are here ❤️
#sciencesky
Reach out to someone that needs some encouragement.
We are here ❤️
#sciencesky
Reposted by Kellie Machlus
We are hiring 😀
Postdoctoral position – Stem cells, Cancer, and Aging
We study cell fate decision and lineage specification in hematopoietic stem and multipotent progenitor populations to modulate lineage output for therapeutic purpose in diseases and aging contexts.
Postdoctoral position – Stem cells, Cancer, and Aging
We study cell fate decision and lineage specification in hematopoietic stem and multipotent progenitor populations to modulate lineage output for therapeutic purpose in diseases and aging contexts.
January 12, 2025 at 12:30 AM
We are hiring 😀
Postdoctoral position – Stem cells, Cancer, and Aging
We study cell fate decision and lineage specification in hematopoietic stem and multipotent progenitor populations to modulate lineage output for therapeutic purpose in diseases and aging contexts.
Postdoctoral position – Stem cells, Cancer, and Aging
We study cell fate decision and lineage specification in hematopoietic stem and multipotent progenitor populations to modulate lineage output for therapeutic purpose in diseases and aging contexts.