Kamal M Khanna
khannakm.bsky.social
Kamal M Khanna
@khannakm.bsky.social
Scientist/Immunologist at NYU school of Medicine. http://khannalab.weebly.com/kamal-m-khanna.html
Pinned
Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis via type I interferon signaling: Immunity www.cell.com/immunity/ful... our study out now in@cp-immunity.bsky.social #macrophages
Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis via type I interferon signaling
The local immunoregulatory mechanisms that safeguard the host from excessive lung infection inflammation remain unclear. Yeung, Yokota et al. uncover the essential role of nerve- and airway-associated...
www.cell.com
Reposted by Kamal M Khanna
Check out this beautiful paper from Isaac Chiu lab, with some contributions from our lab.

www.science.org/doi/10.1126/...

@khannakm.bsky.social
Vagal TRPV1+ sensory neurons protect against influenza virus infection by regulating lung myeloid cell dynamics
TRPV1+ neurons facilitate host survival from flu infection by controlling viral spread, myeloid cell responses, and immunopathology.
www.science.org
August 3, 2025 at 12:24 AM
Reposted by Kamal M Khanna
Brilliant and paradigm shaking new story by Vishwa Deep Dixit's team out this month @naturemetabolism.bsky.social -"Cysteine depletion triggers adipose tissue thermogenesis and weight loss". Congratulations to Deep, Aileen and the entire team on this important work. 🤯
www.nature.com/articles/s42...
Cysteine depletion triggers adipose tissue thermogenesis and weight loss - Nature Metabolism
The authors describe how reduced dietary availability and systemic loss of cysteine leads to adipose tissue browning and rapid weight loss in mice and humans.
www.nature.com
June 9, 2025 at 3:46 AM
Reposted by Kamal M Khanna
Check out the latest review article from #TeamKhanna superstars Eduardo Bernier and recent alumni Dr. Eric Bartnicki.

Macrophages: sentinels, warriors, and healers
Free Link:
academic.oup.com/hmg/advance-...

@khannakm.bsky.social
June 7, 2025 at 6:20 PM
Our latest review on macrophages Macrophages: sentinels, warriors, and healers url:https://academic.oup.com/hmg/article-abstract/doi/10.1093/hmg/ddaf087/8158008

academic.oup.com/hmg/advance-...
Macrophages: sentinels, warriors, and healers
Abstract. Macrophages are versatile innate immune cells that act as sentinels, warriors, and healers in virtually every tissue. This review synthesizes cur
academic.oup.com
June 7, 2025 at 6:12 PM
Reposted by Kamal M Khanna
#WeAreWhatWeEat! #EveryCellIsAnImmuneCell! Dixit, Lee &co show @natmetabolism.nature.com that caloric restriction depletes cysteines, driving weight loss & browning of white adipose tissue via sympathetic nervous system-derived noradrenaline signaling, reversing metabolic inflammation in obese mice!
Cysteine depletion triggers adipose tissue thermogenesis and weight loss - Nature Metabolism
The authors describe how reduced dietary availability and systemic loss of cysteine leads to adipose tissue browning and rapid weight loss in mice and humans.
doi.org
June 4, 2025 at 12:24 PM
Reposted by Kamal M Khanna
Thank you for highlighting this preview of our work by Drs. Rothlin and Ghosh at @yalesph.bsky.social.

What a delight to see this.. 🥹

@khannakm.bsky.social @yeungadventures.bsky.social
May 13, 2025 at 7:22 PM
Reposted by Kamal M Khanna
May issue is online! Explore reviews on the #neuroimmune axis! The beautiful cover was designed by Ella Marushchenko, working with @jonykipnis.bsky.social. A brain encased in a walnut shell that is cracking open symbolizes our growing understanding of #neuroimmunology www.cell.com/immunity/iss...
May 13, 2025 at 4:56 PM
Indeed! Great job Mimi!
Yay!!! #TeamKhanna superstar Mimi Kostoska presenting her work on splenic CD169+ macrophages #aai2025 @khannakm.bsky.social #Khannalab #RTM #staphaureus

Thanks for the picture, @yeungadventures.bsky.social
Beautiful talk on #cd169 #macrophages in response to #staphaureus by PhD student Mimi Kostoska from Khanna Lab @nyulangone.bsky.social so excited to see this work come progressing! @aai.org #immunology2025 #aai2025
May 4, 2025 at 1:02 AM
Reposted by Kamal M Khanna
🫁"Lung Immune Cell Type ‘Quietly’ Controls Inflammation in COVID-19". Congrats @payalyokota.bsky.social, @khannakm.bsky.social, and colleagues!

nyulangone.org/news/lung-im...
Lung Immune Cell Type ‘Quietly’ Controls Inflammation in COVID-19
NYU Langone study shows a type of immune cell in the lungs may help prevent inflammation from spiraling out of control during COVID-19. Learn more.
nyulangone.org
April 29, 2025 at 7:34 PM
Reposted by Kamal M Khanna
www.cbsnews.com/news/scienti...

I wish this was sensationalized or exaggerated - but the impact on US biomedical research outlined in this report is, unfortunately, very much real.
Scientists fear Trump administration cuts to NIH could impact the health of Americans for generations
Former National Institutes of Health Director Dr. Francis Collins, who abruptly left his NIH research lab in February, fears aggressive downsizing could impact Americans' health.
www.cbsnews.com
April 28, 2025 at 12:52 PM
Reposted by Kamal M Khanna
Please watch tonight’s important episode of “60 minutes” focused on the impacts of reductions to the NIH budget and workforce featuring a UW Immunology graduate student.

www.youtube.com/watch?v=noyS...
NIH | Sunday on 60 Minutes
YouTube video by 60 Minutes
www.youtube.com
April 27, 2025 at 9:43 PM
Fantastic and important work @ikinglab.bsky.social
April 27, 2025 at 12:12 PM
Reposted by Kamal M Khanna
Another great study from the @khannakm.bsky.social lab! Disease tolerance to limit Pathology in mucosal tissues
April 26, 2025 at 7:33 PM
Reposted by Kamal M Khanna
Host defense involves both resistance and disease tolerance, a concept elegantly demonstrated in lung viral infection by @yeungadventures.bsky.social @payalyokota.bsky.social @khannakm.bsky.social and colleagues. Spread the word!!
April 26, 2025 at 5:23 PM
Reposted by Kamal M Khanna
So cool!

Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis via type I interferon signaling: Immunity www.cell.com/immunity/ful...
Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis via type I interferon signaling
The local immunoregulatory mechanisms that safeguard the host from excessive lung infection inflammation remain unclear. Yeung, Yokota et al. uncover the essential role of nerve- and airway-associated...
www.cell.com
April 26, 2025 at 12:14 AM
Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis via type I interferon signaling: Immunity www.cell.com/immunity/ful... our study out now in@cp-immunity.bsky.social #macrophages
Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis via type I interferon signaling
The local immunoregulatory mechanisms that safeguard the host from excessive lung infection inflammation remain unclear. Yeung, Yokota et al. uncover the essential role of nerve- and airway-associated...
www.cell.com
April 25, 2025 at 7:18 PM
Reposted by Kamal M Khanna
Excited to share our latest study
@cp-immunity.bsky.social. Heartfelt thanks to the editorial and review teams , to my co-first @yeungadventures.bsky.social, our co-authors, and to @khannakm.bsky.social
for his outstanding mentorship throughout! Pls read/share!👇
www.cell.com/immunity/ful...
Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis via type I interferon signaling
The local immunoregulatory mechanisms that safeguard the host from excessive lung infection inflammation remain unclear. Yeung, Yokota et al. uncover the essential role of nerve- and airway-associated...
www.cell.com
April 25, 2025 at 2:38 PM