Keegan Korthauer 🇨🇦
@keegankorthauer.bsky.social
🧬🖥️ Biologist turned statistician developing tools for (epi)genomics
🇨🇦 Assistant Prof
UBC Stats & BC Children's Hospital Research Institute
https://www.korthauerlab.com/
She/her
🇨🇦 Assistant Prof
UBC Stats & BC Children's Hospital Research Institute
https://www.korthauerlab.com/
She/her
Reposted by Keegan Korthauer 🇨🇦
From @cp-patterns.bsky.social | #Bioconductor: Planning a third decade of comprehensive support for genomic data science | #Bioinformatics #Genomics #OpenScience #OpenSource 🧬 🖥️ 🧪 🔓
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www.cell.com/patterns/ful...
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www.cell.com/patterns/ful...
Bioconductor: Planning a third decade of comprehensive support for genomic data science
This opinion piece discusses the Bioconductor project for open-source bioinformatics
and the engineering concepts underlying its effectiveness to date. Since the inception
of Bioconductor in 2002 with...
www.cell.com
September 11, 2025 at 12:58 PM
From @cp-patterns.bsky.social | #Bioconductor: Planning a third decade of comprehensive support for genomic data science | #Bioinformatics #Genomics #OpenScience #OpenSource 🧬 🖥️ 🧪 🔓
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www.cell.com/patterns/ful...
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www.cell.com/patterns/ful...
Congratulations to Ning Shen on her brilliant PhD defence earlier this week!! 💐👩🏻🎓 I'm extremely lucky to have worked with Ning over the past several years.
September 5, 2025 at 3:48 PM
Congratulations to Ning Shen on her brilliant PhD defence earlier this week!! 💐👩🏻🎓 I'm extremely lucky to have worked with Ning over the past several years.
Reposted by Keegan Korthauer 🇨🇦
Microbiology and Immunology and the Michael Smith Labs are seeking candidates for an Assistant Professor of Teaching in STEM Public Engagement position.
Learn more and apply at: www.msl.ubc.ca/careers/
#IndigenousinSTEM #BlackInNature #WomenInSTEM #MinoritiesInSTEM #DiversityInSTEM #STEMEducation
Learn more and apply at: www.msl.ubc.ca/careers/
#IndigenousinSTEM #BlackInNature #WomenInSTEM #MinoritiesInSTEM #DiversityInSTEM #STEMEducation
July 22, 2025 at 4:01 PM
Microbiology and Immunology and the Michael Smith Labs are seeking candidates for an Assistant Professor of Teaching in STEM Public Engagement position.
Learn more and apply at: www.msl.ubc.ca/careers/
#IndigenousinSTEM #BlackInNature #WomenInSTEM #MinoritiesInSTEM #DiversityInSTEM #STEMEducation
Learn more and apply at: www.msl.ubc.ca/careers/
#IndigenousinSTEM #BlackInNature #WomenInSTEM #MinoritiesInSTEM #DiversityInSTEM #STEMEducation
Reposted by Keegan Korthauer 🇨🇦
My Canadian university, Queen's, is offering TWENTY 4-year funded PhDs (40k CAD/yr) for a student of ANY citizenship who has been accepted at a top 100 US university but have had offer rescinded OR are reconsidering offer due to US policy.
Details found here👇
www.queensu.ca/grad-postdoc...
Details found here👇
www.queensu.ca/grad-postdoc...
Queen’s Special U.S. Doctoral Recruitment Initiative | School of Graduate Studies and Postdoctoral AffairsDown arrowDown arrowDown arrowDown arrowDown arrowDown arrowDown arrowDown arrowDown arrowDown...
Queen’s University is a globally engaged, research-intensive institution dedicated to attracting and supporting exceptional PhD students who will significantly advance our research mission.
www.queensu.ca
June 5, 2025 at 3:31 PM
My Canadian university, Queen's, is offering TWENTY 4-year funded PhDs (40k CAD/yr) for a student of ANY citizenship who has been accepted at a top 100 US university but have had offer rescinded OR are reconsidering offer due to US policy.
Details found here👇
www.queensu.ca/grad-postdoc...
Details found here👇
www.queensu.ca/grad-postdoc...
Now out in Cell Reports - work led by Zheng Dong in collaboration with Kobor group - we characterize the advantages of using updated complete and pangenome references in short-read and array DNA methylation analyses.
www.cell.com/cell-reports...
www.cell.com/cell-reports...
Complete reference genome and pangenome improve genome-wide detection and interpretation of DNA methylation using sequencing and array data
Dong et al. characterized the significant advantages of reference genome updates,
specifically the T2T-CHM13 and the human pangenome, in DNA-methylation analyses. Compared
to the previous GRCh38 assem...
www.cell.com
May 29, 2025 at 8:14 PM
Now out in Cell Reports - work led by Zheng Dong in collaboration with Kobor group - we characterize the advantages of using updated complete and pangenome references in short-read and array DNA methylation analyses.
www.cell.com/cell-reports...
www.cell.com/cell-reports...
🧬 Another new preprint out of the lab: a statistical method and software for cell-type deconvolution of methylated sequencing reads, led by Ning Shen! 🧵👇
doi.org/10.1101/2025...
doi.org/10.1101/2025...
decemedip: hierarchical Bayesian modeling for cell type deconvolution of immunoprecipitation-based DNA methylomes
MeDIP-seq is an enrichment-based DNA methylation profiling technique that measures the abundance of methylated DNA. While this technique offers efficiency advantages over direct methylation profiling,...
doi.org
May 15, 2025 at 7:23 PM
🧬 Another new preprint out of the lab: a statistical method and software for cell-type deconvolution of methylated sequencing reads, led by Ning Shen! 🧵👇
doi.org/10.1101/2025...
doi.org/10.1101/2025...
Exciting new work on GxE associations with the methylome in early life, led by @ericknavarro.bsky.social and collaboration with Kobor lab and others!
🧵 with highlights 👇👇
🧵 with highlights 👇👇
🤔 Have you ever wondered how much does genetics and the environment contribute to shaping the DNA methylome? If the answer is yes, check out some of my latest research!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
RAMEN: Dissecting individual, additive and interactive gene-environment contributions to DNA methylome variability in cord blood
DNA methylation (DNAme) is the most commonly studied epigenetic mark in human populations. DNAme has gained attention in the Developmental Origins of Health and Disease field due to its gene expressio...
www.biorxiv.org
May 15, 2025 at 2:01 AM
Exciting new work on GxE associations with the methylome in early life, led by @ericknavarro.bsky.social and collaboration with Kobor lab and others!
🧵 with highlights 👇👇
🧵 with highlights 👇👇
Reposted by Keegan Korthauer 🇨🇦
Not long after I started my lab, a prominent scientist told me it was “impossible” to be a successful PI and a mother
Don’t ever let the naysayers tell you it can’t be done - of course it can!
#HappyMothersDay this weekend to all the amazing scientist mamas raising their wonderful kids 🥰
Don’t ever let the naysayers tell you it can’t be done - of course it can!
#HappyMothersDay this weekend to all the amazing scientist mamas raising their wonderful kids 🥰
May 9, 2025 at 6:23 PM
Not long after I started my lab, a prominent scientist told me it was “impossible” to be a successful PI and a mother
Don’t ever let the naysayers tell you it can’t be done - of course it can!
#HappyMothersDay this weekend to all the amazing scientist mamas raising their wonderful kids 🥰
Don’t ever let the naysayers tell you it can’t be done - of course it can!
#HappyMothersDay this weekend to all the amazing scientist mamas raising their wonderful kids 🥰
Reposted by Keegan Korthauer 🇨🇦
Applications are open for select graduate studies programs at #SFU, including biomedical physiology, chemistry, molecular biology and @sfuphysics.bsky.social. Canadian and US students encouraged to apply by April 25. www.sfu.ca/gradstudies/...
Lead the Way: Graduate Studies at SFU in Canada for Fall 2025 & Spring 2026
Select SFU graduate programs are opening their applications particularly for Canadian students choosing to remain and study in Canada as well as US students looking to study outside the US. Applicatio...
www.sfu.ca
April 16, 2025 at 6:44 PM
Applications are open for select graduate studies programs at #SFU, including biomedical physiology, chemistry, molecular biology and @sfuphysics.bsky.social. Canadian and US students encouraged to apply by April 25. www.sfu.ca/gradstudies/...
Reposted by Keegan Korthauer 🇨🇦
UBC is hosting US Applicant Week from April 14-18, which allows US students to apply during an extended application period for graduate studies. Sixty graduate programs will be reopening applications for US applicants for September 2025 and January 2026 start dates - www.grad.ubc.ca/us-applicant...
April 7, 2025 at 10:47 PM
UBC is hosting US Applicant Week from April 14-18, which allows US students to apply during an extended application period for graduate studies. Sixty graduate programs will be reopening applications for US applicants for September 2025 and January 2026 start dates - www.grad.ubc.ca/us-applicant...
Reposted by Keegan Korthauer 🇨🇦
Today UHN launches the Canada Leads 100 Challenge! 🇨🇦💯
We’re making an ambitious investment to recruit 100 world-leading scientists. Together, we'll drive the future of health research and position Canada as a leader in global innovation!
Learn more:
www.uhn.ca/corporate/Ab...
We’re making an ambitious investment to recruit 100 world-leading scientists. Together, we'll drive the future of health research and position Canada as a leader in global innovation!
Learn more:
www.uhn.ca/corporate/Ab...
April 7, 2025 at 4:00 PM
Today UHN launches the Canada Leads 100 Challenge! 🇨🇦💯
We’re making an ambitious investment to recruit 100 world-leading scientists. Together, we'll drive the future of health research and position Canada as a leader in global innovation!
Learn more:
www.uhn.ca/corporate/Ab...
We’re making an ambitious investment to recruit 100 world-leading scientists. Together, we'll drive the future of health research and position Canada as a leader in global innovation!
Learn more:
www.uhn.ca/corporate/Ab...
For anyone still using RSS feeds and noticed bioRxiv Collection feeds (www.biorxiv.org/rss) recently broke, here's a quick fix: in the URL for the "All Articles" feed, and replace `all` with the appropriate `coll_alias` from the broken link.
e.g. Genomics feed: connect.biorxiv.org/biorxiv_xml....
e.g. Genomics feed: connect.biorxiv.org/biorxiv_xml....
RSS | bioRxiv
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
www.biorxiv.org
April 4, 2025 at 8:58 PM
For anyone still using RSS feeds and noticed bioRxiv Collection feeds (www.biorxiv.org/rss) recently broke, here's a quick fix: in the URL for the "All Articles" feed, and replace `all` with the appropriate `coll_alias` from the broken link.
e.g. Genomics feed: connect.biorxiv.org/biorxiv_xml....
e.g. Genomics feed: connect.biorxiv.org/biorxiv_xml....
Reposted by Keegan Korthauer 🇨🇦
Canada recently made non-Canadians eligible for federal graduate and postdoctoral fellowships.
For high school students, it takes like 15 minutes to apply to a Canadian university because we don't demand that you produce a cringe-filled PR portfolio to "sell yourself."
For high school students, it takes like 15 minutes to apply to a Canadian university because we don't demand that you produce a cringe-filled PR portfolio to "sell yourself."
March 27, 2025 at 3:59 PM
Canada recently made non-Canadians eligible for federal graduate and postdoctoral fellowships.
For high school students, it takes like 15 minutes to apply to a Canadian university because we don't demand that you produce a cringe-filled PR portfolio to "sell yourself."
For high school students, it takes like 15 minutes to apply to a Canadian university because we don't demand that you produce a cringe-filled PR portfolio to "sell yourself."
Reposted by Keegan Korthauer 🇨🇦
Changes to MSc, PhD and postdoc funding programs from 🇨🇦 tri councils. Harmonization across councils, more awards, and new eligibility for international PhD and postdoc applicants!
NSERC - Latest News - Launch of the new Harmonized Tri-agency Scholarship and Fellowship programs
As announced in Budget 2024, the scholarship and fellowship programs administered by the three federal research funding agencies – the Canadian Institutes of Health Research (CIHR), the Natural Sciences and Engineering Research Council (NSERC), and the Social Sciences and Humanities Research Council (SSHRC) – have been streamlined into a new harmonized talent program called the Canada Research Training Awards Suite (CRTAS) that will open for applications in summer 2025.
www.nserc-crsng.gc.ca
March 14, 2025 at 11:06 PM
Changes to MSc, PhD and postdoc funding programs from 🇨🇦 tri councils. Harmonization across councils, more awards, and new eligibility for international PhD and postdoc applicants!
Reposted by Keegan Korthauer 🇨🇦
Ahead of International Women's Day, and with attacks on critical #DEI programs in the US, I'm resharing this article ⏬
If this regressive shift spreads, we risk undoing many hard-won advances towards gender equality around the world
We cannot let this happen 💪
#Diversity #Equity #Inclusion
If this regressive shift spreads, we risk undoing many hard-won advances towards gender equality around the world
We cannot let this happen 💪
#Diversity #Equity #Inclusion
Women are under-represented at senior levels in #academia globally, & across all #science 🧪 disciplines, as shown by these "scissor-shaped curves" ✂️
So how can we ever achieve #gender #equality?
We discuss various strategies in this #Cell Commentary
#WomeninSTEM
www.cell.com/cell/fulltex...
🧵 1/
So how can we ever achieve #gender #equality?
We discuss various strategies in this #Cell Commentary
#WomeninSTEM
www.cell.com/cell/fulltex...
🧵 1/
March 7, 2025 at 10:18 AM
Ahead of International Women's Day, and with attacks on critical #DEI programs in the US, I'm resharing this article ⏬
If this regressive shift spreads, we risk undoing many hard-won advances towards gender equality around the world
We cannot let this happen 💪
#Diversity #Equity #Inclusion
If this regressive shift spreads, we risk undoing many hard-won advances towards gender equality around the world
We cannot let this happen 💪
#Diversity #Equity #Inclusion
Reposted by Keegan Korthauer 🇨🇦
Made some slides for scientists to talk about what's been happening & what we should do next. There are probably many people better qualified than me to talk about these issues. If that's you, please, please, please consider holding some virtual advocacy training sessions for researchers this week.
The War on Science (Feb 2025 teach-in draft)
The War on Science What’s happening? What can we do about it? An interactive teach-in for biomedical researchers Please share, modify, and repurpose this template presentation (with credit). Good luck...
docs.google.com
February 10, 2025 at 6:30 AM
Made some slides for scientists to talk about what's been happening & what we should do next. There are probably many people better qualified than me to talk about these issues. If that's you, please, please, please consider holding some virtual advocacy training sessions for researchers this week.
Reposted by Keegan Korthauer 🇨🇦
NIH plans to slash support for indirect research costs, sending shockwaves through science
Capping these payments would ‘just grind our scientific complex to a halt,’ one researcher said
@statnews.com
www.statnews.com/2025/02/07/n...
Capping these payments would ‘just grind our scientific complex to a halt,’ one researcher said
@statnews.com
www.statnews.com/2025/02/07/n...
NIH plans to slash support for indirect research costs, sending shockwaves through science
The NIH said Friday night that it would slash support for indirect costs on all existing and future grants to 15%
www.statnews.com
February 8, 2025 at 4:07 PM
NIH plans to slash support for indirect research costs, sending shockwaves through science
Capping these payments would ‘just grind our scientific complex to a halt,’ one researcher said
@statnews.com
www.statnews.com/2025/02/07/n...
Capping these payments would ‘just grind our scientific complex to a halt,’ one researcher said
@statnews.com
www.statnews.com/2025/02/07/n...
Reposted by Keegan Korthauer 🇨🇦
Modern-Day Oracles or Bullshit Machines?
Jevin West (@jevinwest.bsky.social) and I have spent the last eight months developing the course on large language models (LLMs) that we think every college freshman needs to take.
thebullshitmachines.com
Jevin West (@jevinwest.bsky.social) and I have spent the last eight months developing the course on large language models (LLMs) that we think every college freshman needs to take.
thebullshitmachines.com
INTRODUCTION
thebullshitmachines.com
February 4, 2025 at 4:12 PM
Modern-Day Oracles or Bullshit Machines?
Jevin West (@jevinwest.bsky.social) and I have spent the last eight months developing the course on large language models (LLMs) that we think every college freshman needs to take.
thebullshitmachines.com
Jevin West (@jevinwest.bsky.social) and I have spent the last eight months developing the course on large language models (LLMs) that we think every college freshman needs to take.
thebullshitmachines.com
Reposted by Keegan Korthauer 🇨🇦
Reposted by Keegan Korthauer 🇨🇦
All NIH study sections canceled indefinitely. This will halt science and devastate research budgets in universities.
January 22, 2025 at 8:46 PM
All NIH study sections canceled indefinitely. This will halt science and devastate research budgets in universities.
Reposted by Keegan Korthauer 🇨🇦
Today the Trump admin abruptly and indefinitely terminated many of the activities of the National Institutes of Health, the $50B/year collection of agencies that power the US biotech and health ecosystems. Even if these orders were lifted tomorrow, the disruption would be enormous.
Why care? 🧵
Why care? 🧵
Why should the public care about the freeze on the NIH? Aside from the need for scientific pursuits to make our society better…
-For every dollar we invest in NIH research, there is a $2.5 return.
-Research dollars help fund universities that employ non-academics. (1/)
-For every dollar we invest in NIH research, there is a $2.5 return.
-Research dollars help fund universities that employ non-academics. (1/)
January 23, 2025 at 3:14 AM
Today the Trump admin abruptly and indefinitely terminated many of the activities of the National Institutes of Health, the $50B/year collection of agencies that power the US biotech and health ecosystems. Even if these orders were lifted tomorrow, the disruption would be enormous.
Why care? 🧵
Why care? 🧵
Reposted by Keegan Korthauer 🇨🇦
Hi, Vox reporter here: If you've had a study section, NIH travel, or other NIH-related meeting cancelled (or not), raise your hand! Reply or DM me, and repost for visibility if you're able.
#academicsky @drugmonkey.bsky.social
#academicsky @drugmonkey.bsky.social
January 23, 2025 at 6:03 PM
Hi, Vox reporter here: If you've had a study section, NIH travel, or other NIH-related meeting cancelled (or not), raise your hand! Reply or DM me, and repost for visibility if you're able.
#academicsky @drugmonkey.bsky.social
#academicsky @drugmonkey.bsky.social
Reposted by Keegan Korthauer 🇨🇦
I wrote about the ongoing debates over genomic data sharing and the use of such data for "abhorrent science", including some perspective papers that came out last month. A few key points: 🧵
On abhorrent science and the weaponization of genomic data
How to balance open data sharing and public responsibility
open.substack.com
January 12, 2025 at 7:11 PM
I wrote about the ongoing debates over genomic data sharing and the use of such data for "abhorrent science", including some perspective papers that came out last month. A few key points: 🧵