Katy Patras
@katypatras.bsky.social
Associate Professor, studies host-microbe interactions and women's health. Views are my own.
Reposted by Katy Patras
Happy to share this new article online at #mSphere journals.asm.org/doi/10.1128/...
Human nasal organoids (HNOs) are a new model system for studying bacterial colonization and interspecies interactions. A big congratulations to the whole team, especially co-first authors: Andrea Boyd and Leah Kafer
Human nasal organoids (HNOs) are a new model system for studying bacterial colonization and interspecies interactions. A big congratulations to the whole team, especially co-first authors: Andrea Boyd and Leah Kafer
Nasal microbionts differentially colonize and elicit cytokines in human nasal epithelial organoids | mSphere
Human nasal microbiota often includes highly pathogenic members, many of which are
antimicrobial resistance threats, e.g., methicillin-resistant Staphylococcus aureus and drug-resistant Streptococcus ...
journals.asm.org
October 1, 2025 at 5:29 PM
Happy to share this new article online at #mSphere journals.asm.org/doi/10.1128/...
Human nasal organoids (HNOs) are a new model system for studying bacterial colonization and interspecies interactions. A big congratulations to the whole team, especially co-first authors: Andrea Boyd and Leah Kafer
Human nasal organoids (HNOs) are a new model system for studying bacterial colonization and interspecies interactions. A big congratulations to the whole team, especially co-first authors: Andrea Boyd and Leah Kafer
Reposted by Katy Patras
This may be the most important paper ever published about NIH funded research.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
What if NIH had been 40% smaller?
Replaying history with less NIH funding shows widespread impacts on drug-linked research
www.science.org
September 25, 2025 at 9:20 PM
This may be the most important paper ever published about NIH funded research.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
A critical message on the importance of federal funding in supporting global human health.
Please share my 1 min video on the importance of maintaining NIH funding of infectious diseases and drug discovery research vs rising antibiotic resistance
Drastic budget cuts harm our health and imperil the next generation of scientists
More @UCSanDiego “Behind Every Breakthrough” bit.ly/3FlXQs3
Drastic budget cuts harm our health and imperil the next generation of scientists
More @UCSanDiego “Behind Every Breakthrough” bit.ly/3FlXQs3
August 8, 2025 at 12:34 AM
A critical message on the importance of federal funding in supporting global human health.
Excited to share a new preclinical model, human bladder organoids, to study UTI, novel therapies, and beyond! Developed with Dr. Sarah Blutt, the BCM Organoid Core, and @tailor-labs.bsky.social www.biorxiv.org/content/10.1...
Human bladder organoids model urinary tract infection and bacteriophage therapy
Urinary tract infections (UTIs), primarily caused by uropathogenic Escherichia coli (UPEC), are among the most common antibiotic-resistant infections. Despite this, currently available preclinical UTI...
www.biorxiv.org
July 31, 2025 at 12:18 PM
Excited to share a new preclinical model, human bladder organoids, to study UTI, novel therapies, and beyond! Developed with Dr. Sarah Blutt, the BCM Organoid Core, and @tailor-labs.bsky.social www.biorxiv.org/content/10.1...
Reposted by Katy Patras
📣 Dont miss out! Registration just opened for the 6th CSAUTI Conference organized by @globaluti.bsky.social
📆April 9-11th
📍Nashville, TN
utiga.org/registration
📆April 9-11th
📍Nashville, TN
utiga.org/registration
Urinary Tract Infection Global Alliance
No membership fees
Join now!
utiga.org
July 29, 2025 at 7:15 PM
📣 Dont miss out! Registration just opened for the 6th CSAUTI Conference organized by @globaluti.bsky.social
📆April 9-11th
📍Nashville, TN
utiga.org/registration
📆April 9-11th
📍Nashville, TN
utiga.org/registration
Can phage treat infection AND vaccinate? We found that phage treatment protects mice against re-infection by the same pathogen. Out today in PNAS. @tailor-labs.bsky.social www.pnas.org/doi/10.1073/...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
May 30, 2025 at 4:18 PM
Can phage treat infection AND vaccinate? We found that phage treatment protects mice against re-infection by the same pathogen. Out today in PNAS. @tailor-labs.bsky.social www.pnas.org/doi/10.1073/...
Reposted by Katy Patras
Bacteria! We begin with only one!
Bacteria! Two is what we then become!
Bacteria! Each of us becomes two more!
Bacteria! We are stronger than before!
Bacteria! We keep growing at this rate!
Bacteria! No longer shall we wait!
Bacteria! The plan now unfolds!
Bacteria! We will take over the world!
Bacteria! Two is what we then become!
Bacteria! Each of us becomes two more!
Bacteria! We are stronger than before!
Bacteria! We keep growing at this rate!
Bacteria! No longer shall we wait!
Bacteria! The plan now unfolds!
Bacteria! We will take over the world!
May 12, 2025 at 3:07 AM
Bacteria! We begin with only one!
Bacteria! Two is what we then become!
Bacteria! Each of us becomes two more!
Bacteria! We are stronger than before!
Bacteria! We keep growing at this rate!
Bacteria! No longer shall we wait!
Bacteria! The plan now unfolds!
Bacteria! We will take over the world!
Bacteria! Two is what we then become!
Bacteria! Each of us becomes two more!
Bacteria! We are stronger than before!
Bacteria! We keep growing at this rate!
Bacteria! No longer shall we wait!
Bacteria! The plan now unfolds!
Bacteria! We will take over the world!
Good to see @tailor-labs.bsky.social on here at last! Looking forward to more #phage in my feed.
May 9, 2025 at 11:34 PM
Good to see @tailor-labs.bsky.social on here at last! Looking forward to more #phage in my feed.
Reposted by Katy Patras
#UTIhour is TOMORROW at 11am EDT/1500 UTC! Join us on Zoom to learn about host factors affecting #UTI, or check out the recording afterwards! Links to both are / will be available on our site at UTIGA.org/upcoming (zoom) or UTIGA.org/past (recording).
#UTIsky #IDsky
#UTIsky #IDsky
April 29, 2025 at 3:10 PM
#UTIhour is TOMORROW at 11am EDT/1500 UTC! Join us on Zoom to learn about host factors affecting #UTI, or check out the recording afterwards! Links to both are / will be available on our site at UTIGA.org/upcoming (zoom) or UTIGA.org/past (recording).
#UTIsky #IDsky
#UTIsky #IDsky
We found that women with RA have altered vaginal microbial and cytokine signatures, and higher levels of vaginal anti-citrullinated protein antibodies, compared to controls. This study reveals another important mucosal site affected by autoimmune disease. www.medrxiv.org/content/10.1...
A cross-sectional analysis of the vaginal microenvironment in rheumatoid arthritis
Objective: The human microbiota is implicated in the development and progression of rheumatoid arthritis (RA). Given the increased RA burden in women, and well-known correlations between the vaginal m...
www.medrxiv.org
April 14, 2025 at 8:55 PM
We found that women with RA have altered vaginal microbial and cytokine signatures, and higher levels of vaginal anti-citrullinated protein antibodies, compared to controls. This study reveals another important mucosal site affected by autoimmune disease. www.medrxiv.org/content/10.1...
Reposted by Katy Patras
Think UTIs are all about microbes? Think again. #WeAreNotAlltheSame —and your body plays a big role. Mark your calendars to find out who’s at risk April 30th for @globaluti.bsky.social #UTIHour hosted by @katypatras.bsky.social utiga.org/upcoming
April 8, 2025 at 4:50 PM
Think UTIs are all about microbes? Think again. #WeAreNotAlltheSame —and your body plays a big role. Mark your calendars to find out who’s at risk April 30th for @globaluti.bsky.social #UTIHour hosted by @katypatras.bsky.social utiga.org/upcoming
Reposted by Katy Patras
The International Committee on Systematics of Prokaryotes (ICSP) reclassifies Group B 𝘚𝘵𝘳𝘦𝘱𝘵𝘰𝘤𝘰𝘤𝘤𝘶𝘴 as its own genus: 𝘎𝘢𝘭𝘢𝘤𝘵𝘰𝘤𝘰𝘤𝘤𝘶𝘴 𝘭𝘢𝘯𝘤𝘦𝘧𝘪𝘦𝘭𝘥𝘪𝘪
I knew this was possible (e.g. 𝘌𝘯𝘵𝘦𝘳𝘰𝘤𝘰𝘤𝘤𝘶𝘴 used to be Group D 𝘚𝘵𝘳𝘦𝘱𝘵𝘰𝘤𝘰𝘤𝘤𝘶𝘴) but still caught me by surprise
Cool they are honoring Rebecca Lancefield!
I knew this was possible (e.g. 𝘌𝘯𝘵𝘦𝘳𝘰𝘤𝘰𝘤𝘤𝘶𝘴 used to be Group D 𝘚𝘵𝘳𝘦𝘱𝘵𝘰𝘤𝘰𝘤𝘤𝘶𝘴) but still caught me by surprise
Cool they are honoring Rebecca Lancefield!
ICSP Defines New Firmicutes Genus: 𝘎𝘢𝘭𝘢𝘤𝘵𝘰𝘤𝘰𝘤𝘤𝘶𝘴 𝘭𝘢𝘯𝘤𝘦𝘧𝘪𝘦𝘭𝘥𝘪𝘪
The International Committee on Systematics of Prokaryotes Renames Group B 𝘚𝘵𝘳𝘦𝘱𝘵𝘰𝘤𝘰𝘤𝘤𝘶𝘴 as 𝘎𝘢𝘭𝘢𝘤𝘵𝘰𝘤𝘰𝘤𝘤𝘶𝘴 𝘭𝘢𝘯𝘤𝘦𝘧𝘪𝘦𝘭𝘥𝘪𝘪
news.rr.nihalnavath.com
April 1, 2025 at 12:21 PM
The International Committee on Systematics of Prokaryotes (ICSP) reclassifies Group B 𝘚𝘵𝘳𝘦𝘱𝘵𝘰𝘤𝘰𝘤𝘤𝘶𝘴 as its own genus: 𝘎𝘢𝘭𝘢𝘤𝘵𝘰𝘤𝘰𝘤𝘤𝘶𝘴 𝘭𝘢𝘯𝘤𝘦𝘧𝘪𝘦𝘭𝘥𝘪𝘪
I knew this was possible (e.g. 𝘌𝘯𝘵𝘦𝘳𝘰𝘤𝘰𝘤𝘤𝘶𝘴 used to be Group D 𝘚𝘵𝘳𝘦𝘱𝘵𝘰𝘤𝘰𝘤𝘤𝘶𝘴) but still caught me by surprise
Cool they are honoring Rebecca Lancefield!
I knew this was possible (e.g. 𝘌𝘯𝘵𝘦𝘳𝘰𝘤𝘰𝘤𝘤𝘶𝘴 used to be Group D 𝘚𝘵𝘳𝘦𝘱𝘵𝘰𝘤𝘰𝘤𝘤𝘶𝘴) but still caught me by surprise
Cool they are honoring Rebecca Lancefield!
Reposted by Katy Patras
Happy Valentine’s Day from 5 kick ass microbiologists - who all made it to this week’s zoom meeting for the first time in ages! #women #STEM #faculty #science @katypatras.bsky.social @laurainthelab1.bsky.social @lindseyatutk.bsky.social @alisoncoady.bsky.social
February 14, 2025 at 9:45 PM
Happy Valentine’s Day from 5 kick ass microbiologists - who all made it to this week’s zoom meeting for the first time in ages! #women #STEM #faculty #science @katypatras.bsky.social @laurainthelab1.bsky.social @lindseyatutk.bsky.social @alisoncoady.bsky.social
Reposted by Katy Patras
We interrupt your regularly-scheduled chaos to bring you some cool microbiome science. 🦠 🖥️ 🧬
"Longitudinal phage–bacteria dynamics in the early life gut microbiome" now out in Nature Microbiology.
We wanted a way to measure bacteria and phage in metagenomes 1/
www.nature.com/articles/s41...
"Longitudinal phage–bacteria dynamics in the early life gut microbiome" now out in Nature Microbiology.
We wanted a way to measure bacteria and phage in metagenomes 1/
www.nature.com/articles/s41...
Longitudinal phage–bacteria dynamics in the early life gut microbiome - Nature Microbiology
Reanalysis of 12,262 longitudinal infant gut microbiome samples using the Marker-MAGu pipeline revealed phage–bacteria dynamics over the first year of life.
www.nature.com
February 4, 2025 at 8:52 PM
We interrupt your regularly-scheduled chaos to bring you some cool microbiome science. 🦠 🖥️ 🧬
"Longitudinal phage–bacteria dynamics in the early life gut microbiome" now out in Nature Microbiology.
We wanted a way to measure bacteria and phage in metagenomes 1/
www.nature.com/articles/s41...
"Longitudinal phage–bacteria dynamics in the early life gut microbiome" now out in Nature Microbiology.
We wanted a way to measure bacteria and phage in metagenomes 1/
www.nature.com/articles/s41...
After almost a decade (started while I was a postdoc with @nizet.bsky.social and finished by my own stellar students), happy to see this finally out. We found that Tamm-Horsfall protein, the most abundant protein in urine, enhanced NETosis to protect against UTI. insight.jci.org/articles/vie...
JCI Insight -
Tamm-Horsfall protein augments neutrophil NETosis during urinary tract infection
insight.jci.org
January 10, 2025 at 9:28 PM
After almost a decade (started while I was a postdoc with @nizet.bsky.social and finished by my own stellar students), happy to see this finally out. We found that Tamm-Horsfall protein, the most abundant protein in urine, enhanced NETosis to protect against UTI. insight.jci.org/articles/vie...
Reposted by Katy Patras
Infection and Immunity has a call for papers on Women’s Health and the Development of Microbiota in Childhood. For details see journals.asm.org/journal/iai/...
Women’s Health and the Development of Microbiota in Childhood
Explore expert research on women’s health and microbiota development in children
journals.asm.org
December 18, 2024 at 11:05 PM
Infection and Immunity has a call for papers on Women’s Health and the Development of Microbiota in Childhood. For details see journals.asm.org/journal/iai/...
Why is preterm birth risk doubled with maternal UTI? It depends on the immune response. We found distinct immune signatures in a UTI-associated preterm birth mouse model. In a human cohort from @AShea_Lab, urine cytokine levels could predict preterm birth. www.biorxiv.org/content/10.1...
Distinct maternofetal immune signatures delineate preterm birth onset following urinary tract infection
Preterm birth is the leading cause of infant mortality resulting in over one million neonatal deaths annually. Maternal urinary tract infection (UTI) during pregnancy increases risk for preterm birth;...
www.biorxiv.org
October 25, 2024 at 9:57 PM
Why is preterm birth risk doubled with maternal UTI? It depends on the immune response. We found distinct immune signatures in a UTI-associated preterm birth mouse model. In a human cohort from @AShea_Lab, urine cytokine levels could predict preterm birth. www.biorxiv.org/content/10.1...