Karine ALAIN
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kalainxtremmicrob.bsky.social
Karine ALAIN
@kalainxtremmicrob.bsky.social
Research Director at the CNRS, fascinated by microbial physiology and its metabolic versatility, with particular interests in novel metabolic pathways, taxonomy, ecology, and geomicrobiology of microbiomes from extreme environments.
Reposted by Karine ALAIN
Our study on ribonucleotides incorporation the genomes of Haloferax volcanii and Thermococcus barophilus is new published in #NAR #ribonucleasesH
academic.oup.com/nar/article/...
Validate User
academic.oup.com
November 22, 2025 at 11:01 AM
Reposted by Karine ALAIN
Congratulations @daanspeth.bsky.social and the whole team. GlobDB has already been very helpful for several projects at @cemess.bsky.social, and it will no doubt be a useful resource for many microbiologists around the world. Really glad to see it out there.
November 21, 2025 at 6:28 PM
Reposted by Karine ALAIN
We have a date for the free-to-attend #anvio workshop and ECR Symposium for 2026, and we look forward to meeting you at the @hifmb.de in Oldenburg, Germany!

Please find more information on the venue, program, and the application form here, and spread the word 😇

anvio.org/workshops/20...
November 20, 2025 at 6:42 PM
Reposted by Karine ALAIN
A new review study shows the invisible transport pathways for #iron through #hydrothermal plumes.
More on Iron’s Irony here ➡️ www.marum.de/en/Iron-sIro...
@icbm-uol.bsky.social #ConstructorUniversity @geomarkiel.bsky.social @awi.de @marumunibremen.bsky.social
October 20, 2025 at 11:51 AM
Reposted by Karine ALAIN
New article on equitable reuse of public sequencing data, published in @natmicrobiol.nature.com!
Led by the Data reuse core team @lhug.bsky.social @environmicrobio.bsky.social Cristina Moraru, @geomicrosoares.bsky.social, @folker.bsky.social and with Anke Heyer and The Data Reuse Consotrium!
September 26, 2025 at 7:34 PM
Reposted by Karine ALAIN
📢 New paper in @nature.com

Microbes rock 🎸🤘 with sulfide and iron minerals

I am very excited to share our recent study, which describes a previously unknown microbial energy metabolism ⚡⚡⚡🦠🧫⚡⚡⚡

🆕 Microbial iron oxide respiration coupled to sulfide oxidation - MISO

www.nature.com/articles/s41...
Microbial iron oxide respiration coupled to sulfide oxidation - Nature
Genomic and biochemical analyses of prokaryotic sulfur metabolism identify diverse microorganisms with the capacity to oxidize sulfide using iron(iii).
www.nature.com
August 27, 2025 at 8:17 PM
Reposted by Karine ALAIN
Phosphite oxidizers 🤝 Methanogens
In our new paper on “Lithosyntrophy” we show that phosphite oxidation drives methanogenesis through interspecies H2 transfer. Lithosyntrophy establishes a novel mechanistic link between the #phosphorus and carbon redox cycles
Lithosyntrophy: Obligate syntrophy in a phosphite-oxidizing, methanogenic culture https://www.biorxiv.org/content/10.1101/2025.08.26.672485v1
August 27, 2025 at 1:07 PM
Reposted by Karine ALAIN
also the HMM suite for an extensive array of sulfur enzymes is very handy (already used it!) ! :-)
August 28, 2025 at 11:15 AM
Reposted by Karine ALAIN
Bacteria that 'breathe' rocks and sulphur. 🦠🧫
An international team of scientists led by #microbiologists @loyteam.bsky.social and Marc Mussmann have uncovered #bacteria that remove toxic sulfide and use iron #minerals for growth. 🧪🧑‍🔬
Read more here: ⤵️ @cemess.bsky.social
August 28, 2025 at 9:32 AM
Reposted by Karine ALAIN
August 29, 2025 at 5:14 PM
Reposted by Karine ALAIN
Our story about microbial methane is out! We found that reducing the expression of a key gene of methanogenesis modulates the isotopic composition of the methane:
www.science.org/doi/10.1126/...

Check out also the coverage at the UC Berkeley News website:
news.berkeley.edu/2025/08/14/s...
Modulation of methyl–coenzyme M reductase expression alters the isotopic composition of microbial methane
The stable isotopic composition of microbial methane varies substantially, and the underlying causes are debated. In this work, we experimentally controlled the abundance of the central enzyme in meth...
www.science.org
August 21, 2025 at 5:23 PM
Reposted by Karine ALAIN
An organotrophic Sideroxydans reveals potential iron oxidation marker genes journals.asm.org/doi/full/10.... #jcampubs
August 15, 2025 at 4:03 PM
Reposted by Karine ALAIN
The emergence of metabolisms through Earth history and implications for biospheric evolution royalsocietypublishing.org/doi/full/10.... #jcampubs
August 11, 2025 at 4:25 PM
Reposted by Karine ALAIN
Bioenergetics evolution: the link between Earth’s and Life’s history royalsocietypublishing.org/doi/full/10.... #jcampubs
August 11, 2025 at 4:24 PM
Reposted by Karine ALAIN
Fresh out of the oven! 🍞
We're happy to see this preprint out, fruit of a recent collaboration with @wei-biogeochem.bsky.social! 🧬💻

Small 🧵 below going through the main points 👇
www.biorxiv.org/content/10.1...
Uranium mining fuels evolution in deep groundwater microbiomes
Microbial communities in the deep biosphere underpin global biogeochemical cycles, yet their evolutionary responses to extensive anthropogenic disturbances remain unclear. Uranium in-situ leaching (IS...
www.biorxiv.org
August 7, 2025 at 8:05 AM
Our new paper is out:
Sulfur-rich deposits associated with the deep submarine volcano Fani Maoré support broad microbial sulfur cycling communities
doi.org/10.1186/s401...

Video: youtu.be/tPfGzJubvxQ
Sulfur-rich deposits associated with the deep submarine volcano Fani Maoré support broad microbial sulfur cycling communities - Microbiome
Background In 2018, the island of Mayotte located in the western Indian ocean, has experienced a seismo-volcanic crisis linked to the birth of an impressive intraplate submarine volcano at the east of...
doi.org
July 27, 2025 at 11:47 AM