Jay Noboru (登) Worley
@jnobow.bsky.social
Microbiologist/geneticist/bioinformatician. Free-time musician 🎷
Reposted by Jay Noboru (登) Worley
🧪🧪 Nobel laureate Hamilton Smith, who discovered molecular 'scissors' to cut DNA, dies at 94 -- Smith, a microbiologist whose discovery revolutionized the field of genetic engineering, was a Johns Hopkins School of Medicine alumnus and professor emeritus
hub.jhu.edu/2025/11/04/n...
hub.jhu.edu/2025/11/04/n...
Nobel laureate Hamilton Smith, who discovered molecular 'scissors' to cut DNA, dies at 94
Smith, a microbiologist whose discovery revolutionize the field of genetic engineering, was a Johns Hopkins School of Medicine alumnus and professor emeritus
hub.jhu.edu
November 11, 2025 at 7:55 PM
🧪🧪 Nobel laureate Hamilton Smith, who discovered molecular 'scissors' to cut DNA, dies at 94 -- Smith, a microbiologist whose discovery revolutionized the field of genetic engineering, was a Johns Hopkins School of Medicine alumnus and professor emeritus
hub.jhu.edu/2025/11/04/n...
hub.jhu.edu/2025/11/04/n...
Reposted by Jay Noboru (登) Worley
We’re offering free vaccine clinics in Boston. Vaccines are safe, effective, and protect against serious illness. Getting vaccinated keeps you healthy and helps protect your family, friends, and community.
Find upcoming vaccine clinics at boston.gov/vaccine-clinics.
Find upcoming vaccine clinics at boston.gov/vaccine-clinics.
Free Vaccine Clinics in Boston
Everyone ages six months and older is encouraged to get the updated flu and COVID-19 vaccines. Pregnant parents, babies, and older adults should consult their health care professional about RSV vaccin...
boston.gov
October 15, 2025 at 9:09 PM
We’re offering free vaccine clinics in Boston. Vaccines are safe, effective, and protect against serious illness. Getting vaccinated keeps you healthy and helps protect your family, friends, and community.
Find upcoming vaccine clinics at boston.gov/vaccine-clinics.
Find upcoming vaccine clinics at boston.gov/vaccine-clinics.
Reposted by Jay Noboru (登) Worley
NSF today released instructions for the next round of applicants to its Graduate Research Fellowship Program. A key group—second-year Ph.D. students—is no longer eligible, and students who are still able to apply will face an unusually narrow timeframe. https://scim.ag/3KlQkQk
‘Completely shattered.’ Changes to NSF’s graduate student fellowship spur outcry
The announcement comes months later than usual, leaving many would-be applicants stranded
www.science.org
September 26, 2025 at 11:09 PM
NSF today released instructions for the next round of applicants to its Graduate Research Fellowship Program. A key group—second-year Ph.D. students—is no longer eligible, and students who are still able to apply will face an unusually narrow timeframe. https://scim.ag/3KlQkQk
A good reminder to properly source your software!
Heads up: ignore samtools dot org, similarly minimap2 dot com and likely others. It's owned by a known phishing site and while the binaries they offer look valid currently (but note they may be serving us different binaries to others), that could change.
Ie: it's not us (Samtools team)! Be warned
Ie: it's not us (Samtools team)! Be warned
September 15, 2025 at 3:52 PM
A good reminder to properly source your software!
Reposted by Jay Noboru (登) Worley
Awesome to see the transparent, systematic, and evidence-based approach behind the WHO Bacterial Priority Pathogens List 2024 out in the Lancet Infectious Diseases www.thelancet.com/journals/lan...
The WHO Bacterial Priority Pathogens List 2024: a prioritisation study to guide research, development, and public health strategies against antimicrobial resistance
The 2024 WHO BPPL is a key tool for prioritising research and development investments
and informing global public health policies to combat AMR. Gram-negative bacteria
and rifampicin-resistant M tuber...
www.thelancet.com
August 27, 2025 at 4:13 PM
Awesome to see the transparent, systematic, and evidence-based approach behind the WHO Bacterial Priority Pathogens List 2024 out in the Lancet Infectious Diseases www.thelancet.com/journals/lan...
Reposted by Jay Noboru (登) Worley
New York Times story with profiles of researchers whose grants were terminated.
[Gift Link]
www.nytimes.com/2025/08/24/o...
[Gift Link]
www.nytimes.com/2025/08/24/o...
Opinion | America First? Not When It Comes to Your Health.
www.nytimes.com
August 24, 2025 at 1:08 PM
New York Times story with profiles of researchers whose grants were terminated.
[Gift Link]
www.nytimes.com/2025/08/24/o...
[Gift Link]
www.nytimes.com/2025/08/24/o...
Reposted by Jay Noboru (登) Worley
Thrilled that our paper is in print @science.org!!
*Platelets sequester cell free DNA, including free fetal and tumour-derived DNA*
Tweetorial from @l-cmurphy.bsky.social below. Check out the news feature science.org/content/arti... and terrific editorial from Dennis Lo #platelets_in_the_limelight
*Platelets sequester cell free DNA, including free fetal and tumour-derived DNA*
Tweetorial from @l-cmurphy.bsky.social below. Check out the news feature science.org/content/arti... and terrific editorial from Dennis Lo #platelets_in_the_limelight
August 15, 2025 at 5:37 AM
Thrilled that our paper is in print @science.org!!
*Platelets sequester cell free DNA, including free fetal and tumour-derived DNA*
Tweetorial from @l-cmurphy.bsky.social below. Check out the news feature science.org/content/arti... and terrific editorial from Dennis Lo #platelets_in_the_limelight
*Platelets sequester cell free DNA, including free fetal and tumour-derived DNA*
Tweetorial from @l-cmurphy.bsky.social below. Check out the news feature science.org/content/arti... and terrific editorial from Dennis Lo #platelets_in_the_limelight
Reposted by Jay Noboru (登) Worley
Science’s place in society is being renegotiated, as researchers navigate political polarization, shifting federal priorities, and public skepticism. Many of us feel a growing responsibility to engage beyond the lab but don’t always know where to start or how to break through youtu.be/pzYt8up4CoU
Empowering Change with Civic Science
YouTube video by American Society for Microbiology
youtu.be
August 14, 2025 at 8:20 PM
Science’s place in society is being renegotiated, as researchers navigate political polarization, shifting federal priorities, and public skepticism. Many of us feel a growing responsibility to engage beyond the lab but don’t always know where to start or how to break through youtu.be/pzYt8up4CoU
Reposted by Jay Noboru (登) Worley
Requiring grant review by political appointees will continue to delay and disrupt critical research and interferes with scientists’ ability to help protect the nation’s health and security. Read our statement: asm.org/press-releas...
ASM Responds to Improving Oversight of Federal Grantmaking
ASM calls on the Trump Administration to put science ahead of politics and immediately end its plan to force scientific grants to be reviewed by political appointees.
asm.org
August 8, 2025 at 7:55 PM
Requiring grant review by political appointees will continue to delay and disrupt critical research and interferes with scientists’ ability to help protect the nation’s health and security. Read our statement: asm.org/press-releas...
Reposted by Jay Noboru (登) Worley
Here's our new broad review on the extended mobility of plasmids, about all mechanisms driving and limiting their transfer. From conjugation to conduction, phage-plasmids to hitchers, molecular to evolutionary dynamics, ecology to biotech. The state of affairs. 1/9 academic.oup.com/nar/article/...
July 23, 2025 at 7:35 AM
Here's our new broad review on the extended mobility of plasmids, about all mechanisms driving and limiting their transfer. From conjugation to conduction, phage-plasmids to hitchers, molecular to evolutionary dynamics, ecology to biotech. The state of affairs. 1/9 academic.oup.com/nar/article/...
Really nice study that gives me more than a bit to think about - the idea that a probiotic cocktail to prevent C. difficile recurrence might involve strains that colonize transiently and that promote the desired species composition is noteworthy IMO.
New paper is out from our lab showing that some probiotics can accelerate and prolong the return of colonization resistance to C. difficile after antibiotics.
news.ncsu.edu/2025/07/prob...
news.ncsu.edu/2025/07/prob...
Probiotics Can Help or Hinder Gut Recovery After Antibiotic Treatment
news.ncsu.edu
July 21, 2025 at 6:32 PM
Really nice study that gives me more than a bit to think about - the idea that a probiotic cocktail to prevent C. difficile recurrence might involve strains that colonize transiently and that promote the desired species composition is noteworthy IMO.
Reposted by Jay Noboru (登) Worley
A new bionic prosthesis that directly links to the body’s muscles and nerves enables above-knee amputees to move with greater agility, precision, and sensory awareness than traditional devices, researchers report in Science. scim.ag/40YTleG
July 16, 2025 at 6:57 PM
A new bionic prosthesis that directly links to the body’s muscles and nerves enables above-knee amputees to move with greater agility, precision, and sensory awareness than traditional devices, researchers report in Science. scim.ag/40YTleG
Reposted by Jay Noboru (登) Worley
![Comic. [block quote] “Far better an approximate answer to the *right* question, which is often vague, than an *exact* answer to the wrong question, which can always be made precise.” -John W. Tukey, The Future of Data Analysis (1962) [caption] Happy Approximate Birthday to John Tukey, author of my favorite statistics quote, who was born 110.000 years ago sometime this week.](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:cz73r7iyiqn26upot4jtjdhk/bafkreid4vie3df7ltmh7capumhhqcpbejyr7ya7y762fasdeq46ud3gyva@jpeg)
Reposted by Jay Noboru (登) Worley
U.S. drug deaths dropped by roughly 40% last year among people under the age of 35. It's a welcome pivot for families and communities devastated by fentanyl.
Drug deaths plummet among young Americans as fentanyl carnage eases
U.S. drug deaths dropped by roughly 40% last year among people under the age of 35. It's a welcome pivot for families and communities devastated by fentanyl.
n.pr
June 10, 2025 at 1:53 PM
U.S. drug deaths dropped by roughly 40% last year among people under the age of 35. It's a welcome pivot for families and communities devastated by fentanyl.
Reposted by Jay Noboru (登) Worley
Reposted by Jay Noboru (登) Worley
NIH funding supporting the HMMER and Infernal software projects has been terminated. NIH states that our work, as well as all other federally funded research at Harvard, is of no benefit to the US.
May 22, 2025 at 12:42 PM
NIH funding supporting the HMMER and Infernal software projects has been terminated. NIH states that our work, as well as all other federally funded research at Harvard, is of no benefit to the US.
Reposted by Jay Noboru (登) Worley
200+ scientists are in the middle of a marathon livestream to show why weather and climate science is so important and needs all our help to continue.
It is here: wclivestream.com/watch
It is here: wclivestream.com/watch
Redirecting to: https://www.youtube.com/@wclivestream/live
wclivestream.com
May 28, 2025 at 11:03 PM
200+ scientists are in the middle of a marathon livestream to show why weather and climate science is so important and needs all our help to continue.
It is here: wclivestream.com/watch
It is here: wclivestream.com/watch
I read Edward Frenkel's "Love and Math" after Alan Collmer gifted it to me as a PhD grad gift. I still cherish that book, and more than ever, I consider what it means to pass on and share our love of study to the next generation. What would we risk to do so?
May 22, 2025 at 8:34 PM
I read Edward Frenkel's "Love and Math" after Alan Collmer gifted it to me as a PhD grad gift. I still cherish that book, and more than ever, I consider what it means to pass on and share our love of study to the next generation. What would we risk to do so?
Reposted by Jay Noboru (登) Worley
"I'm still in shock. I know that there have been political issues around Harvard in recent weeks, but antibiotic resistance isn't one of them." My conversation with Harvard microbiologist @baym.lol, one of many researchers there who just lost millions in fed. grants. www.wbur.org/news/2025/05...
Antibiotic research at Harvard lab threatened by federal funding cuts
Microbiologist Michael Baym studies antibiotic resistance at Harvard Medical School. He lost millions in federal funding this week.
www.wbur.org
May 16, 2025 at 10:59 PM
"I'm still in shock. I know that there have been political issues around Harvard in recent weeks, but antibiotic resistance isn't one of them." My conversation with Harvard microbiologist @baym.lol, one of many researchers there who just lost millions in fed. grants. www.wbur.org/news/2025/05...
Learned of the passing of Starcadian (George Smaragdis) today. A musical visionary, taken from us too soon. His music was unique and vivid, the hooks instantly memorable, with sophisticated writing. A great sense of drama and sentimentality. If you don't know his music, try Midnight Signals 🕯️
May 5, 2025 at 5:30 PM
Learned of the passing of Starcadian (George Smaragdis) today. A musical visionary, taken from us too soon. His music was unique and vivid, the hooks instantly memorable, with sophisticated writing. A great sense of drama and sentimentality. If you don't know his music, try Midnight Signals 🕯️
Reposted by Jay Noboru (登) Worley
Don't know if already known/obvious, but if you take plates 36, 38, 39 and 45 from Gould's book (darwin-online.org.uk/content/fram...) they align perfectly with the four heads from that later figure. Those original plates are attributed by Gould to Elizabeth (executed on stone by Mrs. Gould).
darwin-online.org.uk
April 8, 2025 at 4:39 PM
Don't know if already known/obvious, but if you take plates 36, 38, 39 and 45 from Gould's book (darwin-online.org.uk/content/fram...) they align perfectly with the four heads from that later figure. Those original plates are attributed by Gould to Elizabeth (executed on stone by Mrs. Gould).
Reposted by Jay Noboru (登) Worley
Delighted to share that @asm.org has met its goal for all of its 'legacy' journals (ie favorites like J. Bact, I&I, AEM) so ALL 2025 articles will be published open access. Thanks to all institutional subscribers, this is the S2O way.
Please submit to these great journals!
asm.org/Press-Releas...
Please submit to these great journals!
asm.org/Press-Releas...
ASM Expands Open Access: 6 Journals Available in 2025 Via S2O
ASM has successfully met its sustainability target for the subscription year under its S2O publishing model. Now, articles in the 2025 volume of ASM’s 6 S2O journals will be published open access.
asm.org
April 2, 2025 at 5:30 PM
Delighted to share that @asm.org has met its goal for all of its 'legacy' journals (ie favorites like J. Bact, I&I, AEM) so ALL 2025 articles will be published open access. Thanks to all institutional subscribers, this is the S2O way.
Please submit to these great journals!
asm.org/Press-Releas...
Please submit to these great journals!
asm.org/Press-Releas...
Reposted by Jay Noboru (登) Worley
"I scarcely ever like to trust any general remark in Zoology, without I find that Botanists concur." Charles Darwin to Asa Gray. August 1856
January 20, 2025 at 11:08 PM
"I scarcely ever like to trust any general remark in Zoology, without I find that Botanists concur." Charles Darwin to Asa Gray. August 1856
Reposted by Jay Noboru (登) Worley
I write a monthly science column for some awesome small-town newspapers in rural New York. My main goal is to actively and diplomatically push back against pseudoscience. I'm the wife of a U.S. diplomat, so I know a few things about diplomacy:🧵🧪🔭
November 24, 2024 at 9:56 AM
I write a monthly science column for some awesome small-town newspapers in rural New York. My main goal is to actively and diplomatically push back against pseudoscience. I'm the wife of a U.S. diplomat, so I know a few things about diplomacy:🧵🧪🔭