Josh Goldford
@jgoldford.bsky.social
Scientist @ Caltech, Entrepreneur, Co-Founder. Interested in the origin and evolution of life on Earth. https://jgoldford.github.io/
Check out our new paper showing that when we add just a handful of hypothetical reactions enabling purine synthesis into modern biochemistry, we can generate a continuous trajectory between ancient geochemistry and modern metabolic networks. www.nature.com/articles/s41...
Primitive purine biosynthesis connects ancient geochemistry to modern metabolism - Nature Ecology & Evolution
Constructing a biosphere-scale model of the evolutionary history of metabolism based on >12,000 biochemical reactions, the authors show that a bottleneck in purine synthesis prevents metabolic expansion from geochemical precursors.
www.nature.com
March 24, 2024 at 7:07 PM
Check out our new paper showing that when we add just a handful of hypothetical reactions enabling purine synthesis into modern biochemistry, we can generate a continuous trajectory between ancient geochemistry and modern metabolic networks. www.nature.com/articles/s41...