Joaquin Nunez
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jcbnunez.bsky.social
Joaquin Nunez
@jcbnunez.bsky.social
I am an Assistant Professor of Biology at the University of Vermont. My lab works on fundamental questions of population genetics as well as ecological and evolutionary genomics.

https://www.jcbnunez.org/
Pinned
doi.org/10.1093/molb...
Thrilled to share our new paper in MBE! 🎉 Presenting DEST 2.0: 530 pooled Drosophila populations spanning 12 years across 6 continents. We map genomic footprints of adaptation, from pesticide resistance to seasonal changes. #PopulationGenetics #Drosophila #Genomics #Evolution
Footprints of Worldwide Adaptation in Structured Populations of Drosophila melanogaster Through the Expanded DEST 2.0 Genomic Resource
Abstract. Large-scale genomic resources can place genetic variation into an ecologically informed context. To advance our understanding of the population g
doi.org
Reposted by Joaquin Nunez
We are in Bluesky and we are happy to share our two last consortium publications: the DrosEU expanded DEST dataset and a Continent-wide study of phenotypic differentiation among European #Drosophila melanogaster populations (1/7)
October 19, 2025 at 9:35 AM
Reposted by Joaquin Nunez
Measuring selection and dominance in fitness of the insecticide-resistant Ace alleles in Drosophila melanogaster, the authors show evidence for beneficial reversal of dominance, a mechanism that can stabilize large-effect polymorphisms in nature. 🧪

www.nature.com/articles/s41...
Beneficial reversal of dominance maintains a large-effect resistance polymorphism under fluctuating insecticide selection - Nature Ecology & Evolution
Measuring selection and dominance in fitness of the insecticide-resistant Ace alleles in Drosophila melanogaster, the authors show evidence for beneficial reversal of dominance, a mechanism that can s...
www.nature.com
September 18, 2025 at 9:23 AM
Exciting to see Sara Helms Cahan quoted in Science, offering her perspective on the awesome reproductive strategies of Iberian harvester ants! www.science.org/content/arti...
Ant queen lays eggs that hatch into two species
Bizarre discovery of interspecies cloning “almost impossible to believe,” biologists say
www.science.org
September 4, 2025 at 1:51 AM
Reposted by Joaquin Nunez
Our department (Berkeley PMB) is hiring an asst. prof. in Plant Resilience to Climate Change! aprecruit.berkeley.edu/JPF05049
Assistant Professor - Plant Resilience to Climate Change - Department of Plant and Microbial Biology
University of California, Berkeley is hiring. Apply now!
aprecruit.berkeley.edu
September 2, 2025 at 9:52 PM
Reposted by Joaquin Nunez
I'm no Cassandra, but I've been exploring this alternative to GS if the Sentient AI Overlords pull the plug on GS. It's this and it is, currently, terrible: openalex.org
August 24, 2025 at 3:47 PM
Reposted by Joaquin Nunez
@jcbnunez.bsky.social et al. present an expanded release of the community-generated resource Drosophila Evolution over Space and Time (DEST 2.0), and showcase it by studying the species' demographic history and signatures of adaptation.

🔗 doi.org/10.1093/molbev/msaf132

#evobio #molbio #drosophila
August 20, 2025 at 5:52 PM
Reposted by Joaquin Nunez
An immense effort with contributions from many authors:
@gonzalezlabbcn.bsky.social
@geneticament.bsky.social
@petrovadmitri.bsky.social
@mgda76.bsky.social
@rawwiberg.bsky.social
@juliabeets.bsky.social
@paucarazo.bsky.social
...and many others...

⬇️ Please tag yourself or other authors below
August 20, 2025 at 5:56 PM
doi.org/10.1093/molb...
Thrilled to share our new paper in MBE! 🎉 Presenting DEST 2.0: 530 pooled Drosophila populations spanning 12 years across 6 continents. We map genomic footprints of adaptation, from pesticide resistance to seasonal changes. #PopulationGenetics #Drosophila #Genomics #Evolution
Footprints of Worldwide Adaptation in Structured Populations of Drosophila melanogaster Through the Expanded DEST 2.0 Genomic Resource
Abstract. Large-scale genomic resources can place genetic variation into an ecologically informed context. To advance our understanding of the population g
doi.org
August 19, 2025 at 1:34 AM
Summer research hits different in Vermont. Lucky to spend the season doing cool science with even cooler people. ☀️✨
July 3, 2025 at 4:38 PM
🎉 Excited to learn that our paper “A cosmopolitan inversion facilitates seasonal adaptation in overwintering Drosophila” is among the most cited recent papers in GENETICS! ☀️❄️ In(2L)t is a key player in seasonal adaptive tracking in fruit flies. academic.oup.com/genetics/art... #Evolution #Genetics
A cosmopolitan inversion facilitates seasonal adaptation in overwintering Drosophila
Abstract. Fluctuations in the strength and direction of natural selection through time are a ubiquitous feature of life on Earth. One evolutionary outcome
academic.oup.com
June 12, 2025 at 1:15 AM
🚨 There is still time to submit a poster for our upcoming Gordon Research Seminar in Ecological & Evolutionary Genomics: Elucidating the Evolutionary Dynamics of Adaptation in Fluctuating Environments! 🧬

Apply now 👉 www.grc.org/ecological-a...
May 14, 2025 at 6:57 PM
Some happy news to share: today we celebrate the inaugural class of the Nunez Lab at UVM! :)
May 10, 2025 at 2:45 AM
Reposted by Joaquin Nunez
Unless there is free lunch....
April 1, 2025 at 8:53 PM
Reposted by Joaquin Nunez
Glorious red aurora occurring now! One of the most pronounced auroral curtains I have ever witnessed. Such a sharp contrast.
March 26, 2025 at 11:34 AM
Reposted by Joaquin Nunez
stdpopsim v0.3.0 is out! You can now mix and match your simulations of different demographic histories with published distributions of fitness effects along with gene annotations, and you can even throw in sweeps for good measure. Check out the new manuscript for more info: doi.org/10.1101/2025...
Accessible, realistic genome simulation with selection using stdpopsim
Selection is a fundamental evolutionary force that shapes patterns of genetic variation across species. However, simulations incorporating realistic selection along heterogeneous genomes in complex de...
doi.org
March 24, 2025 at 6:29 PM
Reposted by Joaquin Nunez
longcallD is a new variant caller for genomic long reads. It jointly calls phased small and structural variants. Single binary, one command line for the whole process. Comparable accuracy to mainstream callers. Great work by Yan Gao. github.com/yangao07/lon...
GitHub - yangao07/longcallD: A local-haplotagging-based small and structural variant caller
A local-haplotagging-based small and structural variant caller - yangao07/longcallD
github.com
March 24, 2025 at 4:53 PM
Reposted by Joaquin Nunez
March 19, 2025 at 9:53 PM
Reposted by Joaquin Nunez
March 20, 2025 at 1:10 AM
Reposted by Joaquin Nunez
The bluebird carries the sky on his back. - Henry David Thoreau

📷: Eastern Bluebird
March 18, 2025 at 11:16 PM
Reposted by Joaquin Nunez
Watching barnacles sweep the ocean for food is so mesmerizing. They look like eyelashes opening and closing. I could watch this for hours. #barnacles #intertidal #marinelife 🦑
March 17, 2025 at 5:47 PM
Excited to be at UNCC today to give the Larry Mays Seminar in Bioinformatics! Looking forward to great discussions with the Genomics and Bioinformatics department and connecting with the UNCC community. #Bioinformatics #Genomics #UNCC
March 14, 2025 at 12:30 PM
🚨 Join us at the GRC/GRS in Italy 🚨 --> Ecological & Evolutionary Genomics Conference (2025)! 🌿🧬 📢 Submit your abstract by April 6 for a chance to give a talk! Co-chairs: @evobioclio.bsky.social and @jcbnunez.bsky.social

🔗 Apply here: www.grc.org/ecological-a...

#Genomics #Evolution #Ecology #GRC
2025 Ecological and Evolutionary Genomics (GRS) Seminar GRC
The 2025 Gordon Research Seminar on Ecological and Evolutionary Genomics (GRS) will be held in Lucca (Barga), Lucca Italy. Apply today to reserve your spot.
www.grc.org
March 12, 2025 at 1:13 PM