Jason Hilton
@jasonhilton.bsky.social
data wrangler, metadata enthusiast
Spent all day hearing about the gambling ring involving current/former NBA players & coach. Spent the evening getting bombarded with gambling ads while watching NBA games.
October 24, 2025 at 8:24 PM
Spent all day hearing about the gambling ring involving current/former NBA players & coach. Spent the evening getting bombarded with gambling ads while watching NBA games.
Really excited for this paper come out. Very impressive to see this community come together, and I would love to see others use it as a framework to address these common issues.
Defining breast epithelial cell types in the single-cell era
Single-cell studies on breast tissue have contributed to a change in our understanding of breast epithelial diversity that has, in turn, precipitated …
www.sciencedirect.com
September 9, 2025 at 6:03 PM
Really excited for this paper come out. Very impressive to see this community come together, and I would love to see others use it as a framework to address these common issues.
Reposted by Jason Hilton
FlyBase needs your help! We ask that European labs continue to contribute to Cambridge, UK FlyBase, whereas US and other non-European labs can contribute to US FlyBase. For more information and how to donate: wiki.flybase.org/wiki/FlyBase...
FlyBase:Contribute to FlyBase - FlyBase Wiki
wiki.flybase.org
August 15, 2025 at 12:45 PM
FlyBase needs your help! We ask that European labs continue to contribute to Cambridge, UK FlyBase, whereas US and other non-European labs can contribute to US FlyBase. For more information and how to donate: wiki.flybase.org/wiki/FlyBase...
First, a quick guide to visiting Lexington, KY:
1. Wear blue, not red
2. Visit my sister-in-law's coffee shop The Greenery (Erin's the one feeding the Governor Alanis lyrics)
1. Wear blue, not red
2. Visit my sister-in-law's coffee shop The Greenery (Erin's the one feeding the Governor Alanis lyrics)
I love a coffee shop that brings a community together like The Greenery. It was great to stop by this new Lexington favorite that put my coffee-making skills to the test. youtu.be/JItFj9Tw7kY
A Governor Behind the Counter: Andy Beshear’s Latte at The Greenery Cafe
YouTube video by Governor Andy Beshear
youtu.be
August 4, 2025 at 3:36 PM
First, a quick guide to visiting Lexington, KY:
1. Wear blue, not red
2. Visit my sister-in-law's coffee shop The Greenery (Erin's the one feeding the Governor Alanis lyrics)
1. Wear blue, not red
2. Visit my sister-in-law's coffee shop The Greenery (Erin's the one feeding the Governor Alanis lyrics)
Congrats @tiagolubiana.bsky.social !
Exceptional Contributions to Biocuration - Early Career Award winner: Tiago Lubiano.
Tiago's a passionate and motivated scientist interested in linked open data, ontologies, the semantic web, and their application in modeling cells and cell types. He is active in many curation projects & with ISB.
Tiago's a passionate and motivated scientist interested in linked open data, ontologies, the semantic web, and their application in modeling cells and cell types. He is active in many curation projects & with ISB.
July 31, 2025 at 5:53 PM
Congrats @tiagolubiana.bsky.social !
@cmungall.bsky.social had me at "structured data nerd". Great perspectives from Chris & @anshulkundaje.bsky.social
Wow, AlphaGenome is a huge deal, 1mb context windows, and prediction of a variety of features, with cell and tissue specificity! Read @anshulkundaje.bsky.social's excellent thread for the details. I want to additionally highlight one additional thing for my structured data nerd friends...
This a really exciting leap forward for genomic sequence to activity gene regulation models. It is a genuine improvement over pretty much all SOTA models spanning a wide range of regulatory, transcriptional and post-transcriptional processes. 1/
July 3, 2025 at 3:29 PM
@cmungall.bsky.social had me at "structured data nerd". Great perspectives from Chris & @anshulkundaje.bsky.social
Highly recommend Nexus by Yuval Noah Harari. Refreshing take on the potential of AI by relating it to innovations, movements & information systems throughout history.
...so read that, watch The Mitchells vs the Machines, and you should be all set for the Age of AI
...so read that, watch The Mitchells vs the Machines, and you should be all set for the Age of AI
May 19, 2025 at 8:27 PM
Highly recommend Nexus by Yuval Noah Harari. Refreshing take on the potential of AI by relating it to innovations, movements & information systems throughout history.
...so read that, watch The Mitchells vs the Machines, and you should be all set for the Age of AI
...so read that, watch The Mitchells vs the Machines, and you should be all set for the Age of AI
Another fun CELLxGENE update from this week: We now support ATAC-seq fragments files. You can download the fragments file for all unpaired scATAC-seq datasets and many multiome datasets. More ATAC-seq features (and data) are coming. Happy #DNADay!
April 25, 2025 at 10:58 PM
Another fun CELLxGENE update from this week: We now support ATAC-seq fragments files. You can download the fragments file for all unpaired scATAC-seq datasets and many multiome datasets. More ATAC-seq features (and data) are coming. Happy #DNADay!
Big CELLxGENE news! No longer just human & mouse data.
Now supported: #celegans #zebrafish #drosophila #rat #pig #rabbit and several non-human primates
Please see info on how to contribute data: cellxgene.cziscience.com/docs/032__Co...
Now supported: #celegans #zebrafish #drosophila #rat #pig #rabbit and several non-human primates
Please see info on how to contribute data: cellxgene.cziscience.com/docs/032__Co...
Cellxgene Data Portal
Find, download, and visually explore curated and standardized single cell datasets.
cellxgene.cziscience.com
April 17, 2025 at 7:58 PM
Big CELLxGENE news! No longer just human & mouse data.
Now supported: #celegans #zebrafish #drosophila #rat #pig #rabbit and several non-human primates
Please see info on how to contribute data: cellxgene.cziscience.com/docs/032__Co...
Now supported: #celegans #zebrafish #drosophila #rat #pig #rabbit and several non-human primates
Please see info on how to contribute data: cellxgene.cziscience.com/docs/032__Co...
"Fortunately, cellxgene classes follow an ontology, a robust structure that defines relationships among the labels." 😍
Very cool to see how they leveraged the ontological relationships to refine many labels!
Very cool to see how they leveraged the ontological relationships to refine many labels!
I am super happy to annonce that after 9 months under review the first paper of my PhD: scPRINT is finally available on Nature Comms! 🎉🧬
www.nature.com/artic...
www.nature.com/artic...
scPRINT: pre-training on 50 million cells allows robust gene network predictions
Nature Communications - Authors present a state-of-the-art cell foundation model trained on 50 million cells. They show that the model generates a meaningful gene network and has zero-shot...
www.nature.com
April 17, 2025 at 3:55 PM
"Fortunately, cellxgene classes follow an ontology, a robust structure that defines relationships among the labels." 😍
Very cool to see how they leveraged the ontological relationships to refine many labels!
Very cool to see how they leveraged the ontological relationships to refine many labels!
So thrilled to see this incredible study published today. Led by some brilliant & amazing people and without these types of studies, any "human <fill in the blank> cell atlas" is destined to just be a "European/white human <fill in the blank> cell atlas".
Asian diversity in human immune cells
The Asian Immune Diversity Atlas (AIDA) is a 5-nation single-cell reference atlas
of circulating immune cells from healthy donors in diverse populations. AIDA highlights
the impact of sub-continental ...
www.cell.com
March 19, 2025 at 11:14 PM
So thrilled to see this incredible study published today. Led by some brilliant & amazing people and without these types of studies, any "human <fill in the blank> cell atlas" is destined to just be a "European/white human <fill in the blank> cell atlas".
Reposted by Jason Hilton
The #GENETICS issue is now live! You'll find updates from 6 model organism databases & other knowledgebases including AgBioData Consortium, Candida Genome Database, @yeastgenome.bsky.social, SpudDB, Unified Phenotype Ontology, & @zfinmod.bsky.social.
What's on the cover? ⬇️🧵
What's on the cover? ⬇️🧵
March 18, 2025 at 4:00 PM
The #GENETICS issue is now live! You'll find updates from 6 model organism databases & other knowledgebases including AgBioData Consortium, Candida Genome Database, @yeastgenome.bsky.social, SpudDB, Unified Phenotype Ontology, & @zfinmod.bsky.social.
What's on the cover? ⬇️🧵
What's on the cover? ⬇️🧵
Reposted by Jason Hilton
A new chapter has begun for two of the world’s most popular preprint platforms, bioRxiv and medRxiv, with the launch of a non-profit organization that will manage them
https://go.nature.com/4iCVnHL
https://go.nature.com/4iCVnHL
Preprint sites bioRxiv and medRxiv launch new era of independence
The popular repositories, where scientists post research before peer review, will be managed by a new organization called openRxiv.
go.nature.com
March 11, 2025 at 2:03 PM
A new chapter has begun for two of the world’s most popular preprint platforms, bioRxiv and medRxiv, with the launch of a non-profit organization that will manage them
https://go.nature.com/4iCVnHL
https://go.nature.com/4iCVnHL
Reposted by Jason Hilton
At #ASHG, we recognize the power of #humangenetics & genomics research in advancing rare disease diagnosis, treatment, and advocacy. In celebrating #RareDiseaseDay, let's push the boundaries of discovery and support the millions of people living with rare genetic conditions.
February 28, 2025 at 2:52 PM
At #ASHG, we recognize the power of #humangenetics & genomics research in advancing rare disease diagnosis, treatment, and advocacy. In celebrating #RareDiseaseDay, let's push the boundaries of discovery and support the millions of people living with rare genetic conditions.
Reposted by Jason Hilton
💜🌍 It’s Rare Disease Day! 🌍💜
Tonight, let’s shine a light for the 300 million people living with a rare disease, including Charcot-Marie-Tooth (CMT).
Join the #LightUpForRare movement @ 7 PM
📸 Share a photo of your lights and tag #LightUpForRare to raise awareness! www.youtube.com/watch?v=fIvq...
Tonight, let’s shine a light for the 300 million people living with a rare disease, including Charcot-Marie-Tooth (CMT).
Join the #LightUpForRare movement @ 7 PM
📸 Share a photo of your lights and tag #LightUpForRare to raise awareness! www.youtube.com/watch?v=fIvq...
February 28, 2025 at 9:37 AM
💜🌍 It’s Rare Disease Day! 🌍💜
Tonight, let’s shine a light for the 300 million people living with a rare disease, including Charcot-Marie-Tooth (CMT).
Join the #LightUpForRare movement @ 7 PM
📸 Share a photo of your lights and tag #LightUpForRare to raise awareness! www.youtube.com/watch?v=fIvq...
Tonight, let’s shine a light for the 300 million people living with a rare disease, including Charcot-Marie-Tooth (CMT).
Join the #LightUpForRare movement @ 7 PM
📸 Share a photo of your lights and tag #LightUpForRare to raise awareness! www.youtube.com/watch?v=fIvq...
Reposted by Jason Hilton
The Global Biodata Coalition is running community webinars on 26 & 27 Feb to discuss their recent White Paper on biodata resource sustainability and seek feedback. View the White Paper and register for the webinar here bit.ly/40PyQ4p.
#biocuration #database #knowledgebase
#biocuration #database #knowledgebase
White Paper - Global Biodata Coalition
bit.ly
February 25, 2025 at 7:31 PM
The Global Biodata Coalition is running community webinars on 26 & 27 Feb to discuss their recent White Paper on biodata resource sustainability and seek feedback. View the White Paper and register for the webinar here bit.ly/40PyQ4p.
#biocuration #database #knowledgebase
#biocuration #database #knowledgebase
Reposted by Jason Hilton
Prior to the #Biocuration Careers workshop at the #Biocurtation2025 conference, we are conducting a survey of biocurators and data stewards about their jobs. Please respond here: forms.gle/DJ7irabs27em...
Biocuration Community Survey 2025
This survey aims to gather and analyze information about the field of biocuration.
This survey is being conducted by the International Society for Biocuration (ISB) to identify potential gaps or ineq...
forms.gle
February 18, 2025 at 8:17 PM
Prior to the #Biocuration Careers workshop at the #Biocurtation2025 conference, we are conducting a survey of biocurators and data stewards about their jobs. Please respond here: forms.gle/DJ7irabs27em...
Embarrassed & ashamed to only just now learn it's #LoveDataWeek. Promise to do better next year. Until then, a corpus of 100M+ cells (and growing) of single-cell expression data, all with raw counts & standardized metadata, and all openly available? That's a lot to love. cellxgene.cziscience.com
Chan Zuckerberg CELLxGENE Discover
Find, download and visually explore curated and standardized single-cell datasets
cellxgene.cziscience.com
February 14, 2025 at 9:35 PM
Embarrassed & ashamed to only just now learn it's #LoveDataWeek. Promise to do better next year. Until then, a corpus of 100M+ cells (and growing) of single-cell expression data, all with raw counts & standardized metadata, and all openly available? That's a lot to love. cellxgene.cziscience.com
Wonderful to see @kendraturkkubo.bsky.social & other friends and colleagues from my grad lab get recognized for their incredible work.
A team of researchers has won the AAAS Newcomb Cleveland Prize for their work identifying a new organelle win single-celled algae that converts nitrogen gas into ammonia. The prize is awarded annually to the author(s) of an outstanding paper published in Research Articles or Reports in Science.
February 14, 2025 at 4:01 PM
Wonderful to see @kendraturkkubo.bsky.social & other friends and colleagues from my grad lab get recognized for their incredible work.
Reposted by Jason Hilton
Thrilled to share PERFF-seq in its final form, where we expand on its sensitivity, applicability, and more! I’m so grateful for the all-star crew (brought together by @caleblareau.bsky.social) that made this happen!! Read thread below for more! 🎉
Out today in @naturegenet.bsky.social -- PERFF-seq! With @tsionabay.bsky.social , @ronanchaligne.bsky.social, Bob Stickels, Meril Takizawa, + Ansu Satpathy, we describe this new assay to study rare populations with programmable nucleic acid cytometry. 1/n
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Transcript-specific enrichment enables profiling of rare cell states via single-cell RNA sequencing - Nature Genetics
Programmable Enrichment via RNA FlowFISH by sequencing (PERFF-seq) isolates rare cells based on RNA marker transcripts for single-cell RNA sequencing profiling of complex tissues, with applicability t...
www.nature.com
January 9, 2025 at 12:58 AM
Thrilled to share PERFF-seq in its final form, where we expand on its sensitivity, applicability, and more! I’m so grateful for the all-star crew (brought together by @caleblareau.bsky.social) that made this happen!! Read thread below for more! 🎉
Open science, data sharing, standards, etc. posts will come. But for now, I just gotta say that the fam has been loving Overcooked 2 on the Switch. Highly recommend, especially if you're looking for a safe space to throw tortillas at your spouse & yell at your kid for burning the rice.
February 7, 2025 at 5:55 PM
Open science, data sharing, standards, etc. posts will come. But for now, I just gotta say that the fam has been loving Overcooked 2 on the Switch. Highly recommend, especially if you're looking for a safe space to throw tortillas at your spouse & yell at your kid for burning the rice.