Amaia Irizar
@iriliza.bsky.social
PhD Scientist. Interested in #DrugDiscovery #Toxicology #Chemicals #NAMs #MachineLearning #CellBiology #ImageAnalysis
Following news on climate, world politics, science and ongoing pandemic.
Following news on climate, world politics, science and ongoing pandemic.
Reposted by Amaia Irizar
Who gives scientific advice to the EU Commission?
The Joint Research Centre, the Commission's in-house science service, has 43 laboratories and 2,000+ researchers who provide independent science for better public policies.
Here we’ll share their findings with the hashtag #JRC
#Science4Policy
The Joint Research Centre, the Commission's in-house science service, has 43 laboratories and 2,000+ researchers who provide independent science for better public policies.
Here we’ll share their findings with the hashtag #JRC
#Science4Policy
October 1, 2025 at 12:10 PM
Who gives scientific advice to the EU Commission?
The Joint Research Centre, the Commission's in-house science service, has 43 laboratories and 2,000+ researchers who provide independent science for better public policies.
Here we’ll share their findings with the hashtag #JRC
#Science4Policy
The Joint Research Centre, the Commission's in-house science service, has 43 laboratories and 2,000+ researchers who provide independent science for better public policies.
Here we’ll share their findings with the hashtag #JRC
#Science4Policy
Reposted by Amaia Irizar
Webinar: Future perspectives on artificial intelligence in safety assessment
Three leading experts will discuss how AI and approaches such as machine learning can be used to improve toxicity prediction and reduce the reliance on animal models.
📅 25 September, 14.00
👉 nc3rs.org.uk/events/artif...
Three leading experts will discuss how AI and approaches such as machine learning can be used to improve toxicity prediction and reduce the reliance on animal models.
📅 25 September, 14.00
👉 nc3rs.org.uk/events/artif...
August 27, 2025 at 10:41 AM
Webinar: Future perspectives on artificial intelligence in safety assessment
Three leading experts will discuss how AI and approaches such as machine learning can be used to improve toxicity prediction and reduce the reliance on animal models.
📅 25 September, 14.00
👉 nc3rs.org.uk/events/artif...
Three leading experts will discuss how AI and approaches such as machine learning can be used to improve toxicity prediction and reduce the reliance on animal models.
📅 25 September, 14.00
👉 nc3rs.org.uk/events/artif...
Reposted by Amaia Irizar
Call for Posters: NAMs in Preclinical Imaging
Showcase how your team is integrating organoids, AI, lab-on-chip systems, etc into imaging workflows. Join the #NAMs spotlight at #WMIC2025!
📅 Poster Submission Deadline: August 29, 2025
🔗 More details: wmis.org/wmic1/abstra...
Showcase how your team is integrating organoids, AI, lab-on-chip systems, etc into imaging workflows. Join the #NAMs spotlight at #WMIC2025!
📅 Poster Submission Deadline: August 29, 2025
🔗 More details: wmis.org/wmic1/abstra...
July 25, 2025 at 2:01 PM
Call for Posters: NAMs in Preclinical Imaging
Showcase how your team is integrating organoids, AI, lab-on-chip systems, etc into imaging workflows. Join the #NAMs spotlight at #WMIC2025!
📅 Poster Submission Deadline: August 29, 2025
🔗 More details: wmis.org/wmic1/abstra...
Showcase how your team is integrating organoids, AI, lab-on-chip systems, etc into imaging workflows. Join the #NAMs spotlight at #WMIC2025!
📅 Poster Submission Deadline: August 29, 2025
🔗 More details: wmis.org/wmic1/abstra...
Reposted by Amaia Irizar
So…about AI’s energy use…
“…to create a five-second video, a newer AI model uses ‘about 3.4 million joules, more than 700 times the energy required to generate a high-quality image’. That's the equivalent of running a microwave for over an hour.”
“…to create a five-second video, a newer AI model uses ‘about 3.4 million joules, more than 700 times the energy required to generate a high-quality image’. That's the equivalent of running a microwave for over an hour.”
Report: Creating a 5-second AI video is like running a microwave for an hour
That's a long time in the microwave.
mashable.com
May 22, 2025 at 5:04 PM
So…about AI’s energy use…
“…to create a five-second video, a newer AI model uses ‘about 3.4 million joules, more than 700 times the energy required to generate a high-quality image’. That's the equivalent of running a microwave for over an hour.”
“…to create a five-second video, a newer AI model uses ‘about 3.4 million joules, more than 700 times the energy required to generate a high-quality image’. That's the equivalent of running a microwave for over an hour.”
Reposted by Amaia Irizar
responses
- Omicron's spike proteins tend to adopt a conformation that hides the key sites of the protein for neutralization
- Omicron's spike proteins are expressed at lower levels on viral particles, which means it's harder to target with antibodies
These issues are addressable.
- Omicron's spike proteins tend to adopt a conformation that hides the key sites of the protein for neutralization
- Omicron's spike proteins are expressed at lower levels on viral particles, which means it's harder to target with antibodies
These issues are addressable.
Framing the Imprint: Omicron and Original Antigenic Sin
Imprinting has been blamed as a key factor for the lackluster responses to the Omicron spike protein. In fact, the fault may be with Omicron itself (and we might be able to do things about that).
deplatformdisease.substack.com
May 22, 2025 at 7:33 PM
responses
- Omicron's spike proteins tend to adopt a conformation that hides the key sites of the protein for neutralization
- Omicron's spike proteins are expressed at lower levels on viral particles, which means it's harder to target with antibodies
These issues are addressable.
- Omicron's spike proteins tend to adopt a conformation that hides the key sites of the protein for neutralization
- Omicron's spike proteins are expressed at lower levels on viral particles, which means it's harder to target with antibodies
These issues are addressable.
Reposted by Amaia Irizar
There are two weeks left to take part in our stakeholder survey on new approach methodologies to tell us your priority areas and unmet needs that if addressed would facilitate the use of NAMs in safety assessment.
⏳ The survey closes on Tuesday 3 June: nc3rs.org.uk/our-portfoli...
⏳ The survey closes on Tuesday 3 June: nc3rs.org.uk/our-portfoli...
SURVEY: New approach methodologies in safety assessment
Are you involved in the development and application of replacement technologies for toxicity testing or submission and assessment of data for regulatory decision making? Help shape our plans for the coming years: nc3rs.org.uk/our-portfoli...
Are you involved in the development and application of replacement technologies for toxicity testing or submission and assessment of data for regulatory decision making? Help shape our plans for the coming years: nc3rs.org.uk/our-portfoli...
May 20, 2025 at 10:38 AM
There are two weeks left to take part in our stakeholder survey on new approach methodologies to tell us your priority areas and unmet needs that if addressed would facilitate the use of NAMs in safety assessment.
⏳ The survey closes on Tuesday 3 June: nc3rs.org.uk/our-portfoli...
⏳ The survey closes on Tuesday 3 June: nc3rs.org.uk/our-portfoli...
Reposted by Amaia Irizar
Thank God for immigrants open.substack.com/pub/iandunt/...
Thank God for immigrants
This week, of all weeks: Thank God they came here and chose to make it their home.
open.substack.com
May 16, 2025 at 7:11 AM
Thank God for immigrants open.substack.com/pub/iandunt/...
Reposted by Amaia Irizar
Ongoing @who.int pandemic situational reports www.who.int/emergencies/...
April 23, 2025 at 7:17 AM
Ongoing @who.int pandemic situational reports www.who.int/emergencies/...
Reposted by Amaia Irizar
We live in a country where this didn’t make the press.
April 21, 2025 at 6:42 AM
We live in a country where this didn’t make the press.
Reposted by Amaia Irizar
Barry Hardy (Edelweiss Connect, #RISK-HUNT3R partner) at #2025SOT discussing #NGRA advancements, practical applications, and RISK-HUNT3R #casestudies for #industrial use & #regulatory #acceptance.
A key advancement is the #ASPA initiative, as part of the #ASPIScluster.
📽️ youtu.be/_6-EDrKQEEE?...
A key advancement is the #ASPA initiative, as part of the #ASPIScluster.
📽️ youtu.be/_6-EDrKQEEE?...
US SOT 2025: SOT Stories No.2 with Barry Hardy
YouTube video by ASPIS cluster
youtu.be
April 4, 2025 at 9:09 AM
Barry Hardy (Edelweiss Connect, #RISK-HUNT3R partner) at #2025SOT discussing #NGRA advancements, practical applications, and RISK-HUNT3R #casestudies for #industrial use & #regulatory #acceptance.
A key advancement is the #ASPA initiative, as part of the #ASPIScluster.
📽️ youtu.be/_6-EDrKQEEE?...
A key advancement is the #ASPA initiative, as part of the #ASPIScluster.
📽️ youtu.be/_6-EDrKQEEE?...
Reposted by Amaia Irizar
The US Christian evangelical right have joined forces with The Heritage Foundation, (the authors of Project 2025), and right wing lobby groups and think tanks from Pland and Hungary to dismantle the European Union and the European Court of Justice.
Thread
Thread
Right-wing push to dismantle the EU: Heritage Foundation’s private workshop
After seizing control of the US government, the Heritage Foundation turns its attention to the EU
yorkshirebylines.co.uk
March 27, 2025 at 10:39 PM
The US Christian evangelical right have joined forces with The Heritage Foundation, (the authors of Project 2025), and right wing lobby groups and think tanks from Pland and Hungary to dismantle the European Union and the European Court of Justice.
Thread
Thread
Reposted by Amaia Irizar
March 27, 2025 at 5:21 PM
Reposted by Amaia Irizar
Most tech bros have no idea who this woman was
March 27, 2025 at 7:14 PM
Most tech bros have no idea who this woman was
Reposted by Amaia Irizar
It’s just heartbreaking. Soul destroying. Depraved.
27 PAGES of children’s names, killed, who were not even 1 year old.
27 PAGES of children’s names, killed, who were not even 1 year old.
This report should break something in all of us.
15,613 children.
The first 27 pages of the report list children whose ages are 0.
26% were under the age of 5
15,613 children.
The first 27 pages of the report list children whose ages are 0.
26% were under the age of 5
March 27, 2025 at 9:27 PM
It’s just heartbreaking. Soul destroying. Depraved.
27 PAGES of children’s names, killed, who were not even 1 year old.
27 PAGES of children’s names, killed, who were not even 1 year old.
Reposted by Amaia Irizar
If you’re interested in a crash course from the beginning in chronic issues with COVID I recommend this excellent interview with David Putrino. Perhaps the least well understood consequence is the damage every infection likely causes everyone, symptomatic or not.
www.cbc.ca/player/play/...
www.cbc.ca/player/play/...
Beyond long COVID — how reinfections could be causing silent long term organ damage
It’s now been five years since the COVID pandemic stopped the world in its tracks. The virus is still with us, and continues to make people sick. As many as 1 in 5 Canadians have experienced symptoms ...
www.cbc.ca
March 15, 2025 at 9:42 PM
If you’re interested in a crash course from the beginning in chronic issues with COVID I recommend this excellent interview with David Putrino. Perhaps the least well understood consequence is the damage every infection likely causes everyone, symptomatic or not.
www.cbc.ca/player/play/...
www.cbc.ca/player/play/...
Reposted by Amaia Irizar
SAVE THE DATE - our last 2 conferences of 2025...
🔬 Drug Discovery 2025 - A Festival of Life Science
Liverpool 21-22 October
📊 High-Content Imaging and Flow Cytometry in Drug Discovery 2025
Stevenage 19-20 November
Find out more here - elrig.org
🔬 Drug Discovery 2025 - A Festival of Life Science
Liverpool 21-22 October
📊 High-Content Imaging and Flow Cytometry in Drug Discovery 2025
Stevenage 19-20 November
Find out more here - elrig.org
January 6, 2025 at 3:46 PM
SAVE THE DATE - our last 2 conferences of 2025...
🔬 Drug Discovery 2025 - A Festival of Life Science
Liverpool 21-22 October
📊 High-Content Imaging and Flow Cytometry in Drug Discovery 2025
Stevenage 19-20 November
Find out more here - elrig.org
🔬 Drug Discovery 2025 - A Festival of Life Science
Liverpool 21-22 October
📊 High-Content Imaging and Flow Cytometry in Drug Discovery 2025
Stevenage 19-20 November
Find out more here - elrig.org
Reposted by Amaia Irizar
Women are under-represented at senior levels in #academia globally, & across all #science 🧪 disciplines, as shown by these "scissor-shaped curves" ✂️
So how can we ever achieve #gender #equality?
We discuss various strategies in this #Cell Commentary
#WomeninSTEM
www.cell.com/cell/fulltex...
🧵 1/
So how can we ever achieve #gender #equality?
We discuss various strategies in this #Cell Commentary
#WomeninSTEM
www.cell.com/cell/fulltex...
🧵 1/
November 25, 2024 at 12:38 PM
Women are under-represented at senior levels in #academia globally, & across all #science 🧪 disciplines, as shown by these "scissor-shaped curves" ✂️
So how can we ever achieve #gender #equality?
We discuss various strategies in this #Cell Commentary
#WomeninSTEM
www.cell.com/cell/fulltex...
🧵 1/
So how can we ever achieve #gender #equality?
We discuss various strategies in this #Cell Commentary
#WomeninSTEM
www.cell.com/cell/fulltex...
🧵 1/
Reposted by Amaia Irizar
You may be familiar with Próspera, the special economic zone + tech hub on a Honduran island supported by Peter Thiel, Marc Andreessen, etc.
Many groups now pushing the Trump admin for deregulated “freedom cities” in the US work in/have ties to Próspera:
www.wired.com/story/startu...
Many groups now pushing the Trump admin for deregulated “freedom cities” in the US work in/have ties to Próspera:
www.wired.com/story/startu...
‘Startup Nation’ Groups Say They’re Meeting Trump Officials to Push for Deregulated ‘Freedom Cities’
The architects of projects like Próspera are drafting legislation to create US cities that would be free from federal regulations.
www.wired.com
March 7, 2025 at 8:19 PM
You may be familiar with Próspera, the special economic zone + tech hub on a Honduran island supported by Peter Thiel, Marc Andreessen, etc.
Many groups now pushing the Trump admin for deregulated “freedom cities” in the US work in/have ties to Próspera:
www.wired.com/story/startu...
Many groups now pushing the Trump admin for deregulated “freedom cities” in the US work in/have ties to Próspera:
www.wired.com/story/startu...
Reposted by Amaia Irizar
Why Are People Wearing Masks in 2025?
open.substack.com/pub/misfitme...
open.substack.com/pub/misfitme...
Why Are People Wearing Masks in 2025?
a mental health professional’s perspective
open.substack.com
March 1, 2025 at 8:56 PM
Why Are People Wearing Masks in 2025?
open.substack.com/pub/misfitme...
open.substack.com/pub/misfitme...
Animal-free safety assessment of chemicals: an innovation system perspective doi.org/10.1007/s002...
#NAMs
#NAMs
Animal-free safety assessment of chemicals: an innovation system perspective - Archives of Toxicology
This perspective paper, which is the result of a collaborative effort between toxicologists and scholars in innovation and transition studies, presents a heuristic framework based on innovation system...
doi.org
January 18, 2025 at 12:27 PM
Animal-free safety assessment of chemicals: an innovation system perspective doi.org/10.1007/s002...
#NAMs
#NAMs
WithdrarXiv, the first large-scale dataset of withdrawn papers from arXiv, containing over 14,000 papers and their associated retraction comments spanning the repository's entire history through September 2024 arxiv.org/abs/2412.03775
WithdrarXiv: A Large-Scale Dataset for Retraction Study
Retractions play a vital role in maintaining scientific integrity, yet systematic studies of retractions in computer science and other STEM fields remain scarce. We present WithdrarXiv, the first larg...
arxiv.org
December 20, 2024 at 11:59 AM
WithdrarXiv, the first large-scale dataset of withdrawn papers from arXiv, containing over 14,000 papers and their associated retraction comments spanning the repository's entire history through September 2024 arxiv.org/abs/2412.03775
Reposted by Amaia Irizar
THREAD
This Is The Story Of The The Pernicious Rise of AI-Generated Papers and their Online Impact
An Incomplete History Told In The Voice of Documentarian Adam Curtis
1/31
This Is The Story Of The The Pernicious Rise of AI-Generated Papers and their Online Impact
An Incomplete History Told In The Voice of Documentarian Adam Curtis
1/31
December 19, 2024 at 9:10 PM
THREAD
This Is The Story Of The The Pernicious Rise of AI-Generated Papers and their Online Impact
An Incomplete History Told In The Voice of Documentarian Adam Curtis
1/31
This Is The Story Of The The Pernicious Rise of AI-Generated Papers and their Online Impact
An Incomplete History Told In The Voice of Documentarian Adam Curtis
1/31
Great to see @nc3rs.bsky.social in this site. Hopefully this will help attract more migration from the #NAMs community.
December 18, 2024 at 2:15 PM
Great to see @nc3rs.bsky.social in this site. Hopefully this will help attract more migration from the #NAMs community.
Reposted by Amaia Irizar
There's a 🆕 journal on the scene 🚨 The #NAMJournal welcomes manuscripts on all aspects of the non-animal research method lifecycle, including in biomedical research. Congrats to editors Mathieu Vinken, Michelle Embry, & Fenna Sillé.
#NAMs
www.sciencedirect.com/journal/nam-...
#NAMs
www.sciencedirect.com/journal/nam-...
November 21, 2024 at 10:15 PM
There's a 🆕 journal on the scene 🚨 The #NAMJournal welcomes manuscripts on all aspects of the non-animal research method lifecycle, including in biomedical research. Congrats to editors Mathieu Vinken, Michelle Embry, & Fenna Sillé.
#NAMs
www.sciencedirect.com/journal/nam-...
#NAMs
www.sciencedirect.com/journal/nam-...
Reposted by Amaia Irizar
You can now watch the I2K video tutorial on #micro-sam by @anwaiarchit.bsky.social on YouTube: www.youtube.com/watch?v=dxjU... Check it out for an in-depth explanation for how to use our tool to segment your microscopy images.
Segment Anything for Microscopy
YouTube video by I2K Conference
www.youtube.com
November 30, 2024 at 5:14 PM
You can now watch the I2K video tutorial on #micro-sam by @anwaiarchit.bsky.social on YouTube: www.youtube.com/watch?v=dxjU... Check it out for an in-depth explanation for how to use our tool to segment your microscopy images.