Inyoung Jeong (Jung)
@inyoungj88.bsky.social
Neurobiologist, Postdoctoral researcher at NTNU in Norway🇳🇴🇰🇷, Interested in CSF, choroid plexus, cilia, glia, neuropeptides/GPCR, neural circuits, etc.
Reposted by Inyoung Jeong (Jung)
Preprint -
Excited to present WHOLISTIC, which extends the concept of whole-brain functional imaging to the entire body. Pioneering work by incredibly talented Virginia Ruetten @vmsruetten.bsky.social, this platform reveals whole-organism cellular dynamics in vivo.
www.biorxiv.org/content/10.1...
Excited to present WHOLISTIC, which extends the concept of whole-brain functional imaging to the entire body. Pioneering work by incredibly talented Virginia Ruetten @vmsruetten.bsky.social, this platform reveals whole-organism cellular dynamics in vivo.
www.biorxiv.org/content/10.1...
September 8, 2025 at 4:25 PM
Preprint -
Excited to present WHOLISTIC, which extends the concept of whole-brain functional imaging to the entire body. Pioneering work by incredibly talented Virginia Ruetten @vmsruetten.bsky.social, this platform reveals whole-organism cellular dynamics in vivo.
www.biorxiv.org/content/10.1...
Excited to present WHOLISTIC, which extends the concept of whole-brain functional imaging to the entire body. Pioneering work by incredibly talented Virginia Ruetten @vmsruetten.bsky.social, this platform reveals whole-organism cellular dynamics in vivo.
www.biorxiv.org/content/10.1...
Reposted by Inyoung Jeong (Jung)
New very cool work from the Yaksi lab:
Hierarchical processing of sensory information across topographically organized thalamocortical-like circuits in the zebrafish brain
www.biorxiv.org/content/10.1...
Hierarchical processing of sensory information across topographically organized thalamocortical-like circuits in the zebrafish brain
www.biorxiv.org/content/10.1...
Hierarchical processing of sensory information across topographically organized thalamocortical-like circuits in the zebrafish brain
Thalamocortical projections contribute to the spatial organization and functional hierarchies of the mammalian cortex. Primary sensory cortices receive topographically segregated information from firs...
www.biorxiv.org
September 16, 2025 at 7:13 PM
New very cool work from the Yaksi lab:
Hierarchical processing of sensory information across topographically organized thalamocortical-like circuits in the zebrafish brain
www.biorxiv.org/content/10.1...
Hierarchical processing of sensory information across topographically organized thalamocortical-like circuits in the zebrafish brain
www.biorxiv.org/content/10.1...
Reposted by Inyoung Jeong (Jung)
🚩Publication Alert🚩"Advection vs. Diffusion in Brain Ventricular Transport" by Herlyng at al in collaboration with @utropstegn.bsky.social at @simularesearch.bsky.social and Jebsen Centre for Brain Fluid Research is now published in Fluids and Barriers of the CNS! 🧠💧
Advection versus diffusion in brain ventricular transport - Fluids and Barriers of the CNS
Cerebrospinal fluid (CSF) is integral to brain function. CSF provides mechanical support for the brain and helps distribute nutrients, neurotransmitters and metabolites throughout the central nervous ...
doi.org
August 14, 2025 at 11:37 AM
🚩Publication Alert🚩"Advection vs. Diffusion in Brain Ventricular Transport" by Herlyng at al in collaboration with @utropstegn.bsky.social at @simularesearch.bsky.social and Jebsen Centre for Brain Fluid Research is now published in Fluids and Barriers of the CNS! 🧠💧
Reposted by Inyoung Jeong (Jung)
New publication from our lab is just out! rdcu.be/ezk1U
In brief, we showed that glutamate-driven inhibition in the habenula can alter neural activity and connectivity, leading to amplified sensory responses and defensive behaviors.
In brief, we showed that glutamate-driven inhibition in the habenula can alter neural activity and connectivity, leading to amplified sensory responses and defensive behaviors.
Inhibition mediated by group III metabotropic glutamate receptors regulates habenula activity and defensive behaviors
Nature Communications - The role of glutamate-driven inhibition in neural computations and animal behavior is not fully understood. This study reveals that group III metabotropic glutamate...
rdcu.be
August 5, 2025 at 5:04 PM
New publication from our lab is just out! rdcu.be/ezk1U
In brief, we showed that glutamate-driven inhibition in the habenula can alter neural activity and connectivity, leading to amplified sensory responses and defensive behaviors.
In brief, we showed that glutamate-driven inhibition in the habenula can alter neural activity and connectivity, leading to amplified sensory responses and defensive behaviors.
Reposted by Inyoung Jeong (Jung)
Our paper on zebrafish phenotypes in Alzheimer’s risk genes finally is now in its final form at Elife!
Behavioural #pharmacology predicts signalling pathways that could be drug targets in #zebrafish with #Alzheimer’s disease risk genes.
https://elifesciences.org/articles/96839?utm_source=bluesky&utm_medium=social&utm_campaign=organic
https://elifesciences.org/articles/96839?utm_source=bluesky&utm_medium=social&utm_campaign=organic
February 24, 2025 at 10:05 AM
Our paper on zebrafish phenotypes in Alzheimer’s risk genes finally is now in its final form at Elife!
Reposted by Inyoung Jeong (Jung)
With everything that's going on, I needed this cool data 1 day before #flourescencefriday. It's my first time with #GCaMP imaging (green), and you can clearly see Aβ42 induced hyperexcitability at the same time that we also see BBB leakage (not shown)! #zebrafishrock
February 28, 2025 at 1:32 AM
With everything that's going on, I needed this cool data 1 day before #flourescencefriday. It's my first time with #GCaMP imaging (green), and you can clearly see Aβ42 induced hyperexcitability at the same time that we also see BBB leakage (not shown)! #zebrafishrock
Reposted by Inyoung Jeong (Jung)
Online now: Glymphatics and meningeal lymphatics unlock the brain-immune code
Glymphatics and meningeal lymphatics unlock the brain-immune code
Recent discoveries of glymphatics and meningeal lymphatics have redefined our understanding of CNS immunosurveillance. Kim and Kipnis illustrate how the clearance of brain-derived antigens creates an “immune code” that, when presented by meningeal antigen-presenting cells, instructs T cells to safeguard neural homeostasis. They review how inflammation, aging, and neurodegeneration disrupt this finely tuned process and highlight emerging therapeutic opportunities.
dlvr.it
May 4, 2025 at 2:48 PM
Online now: Glymphatics and meningeal lymphatics unlock the brain-immune code
Reposted by Inyoung Jeong (Jung)
Our perspective in @natrevimmunol.nature.com on new concepts in neuroimmune interactions that have challenged the old dogma that immune privilege is a result of the isolation of the nervous and immune systems.
@jonykipnis.bsky.social
www.nature.com/articles/s41...
@jonykipnis.bsky.social
www.nature.com/articles/s41...
Redefining CNS immune privilege - Nature Reviews Immunology
In this Perspective, Smyth and Kipnis reappraise the concept of immune privilege in the central nervous system. Although immune privilege was originally thought to involve isolation of the central ner...
www.nature.com
May 2, 2025 at 8:05 PM
Our perspective in @natrevimmunol.nature.com on new concepts in neuroimmune interactions that have challenged the old dogma that immune privilege is a result of the isolation of the nervous and immune systems.
@jonykipnis.bsky.social
www.nature.com/articles/s41...
@jonykipnis.bsky.social
www.nature.com/articles/s41...
Reposted by Inyoung Jeong (Jung)
Free link below: rdcu.be/ekqtw
Redefining CNS immune privilege
Nature Reviews Immunology - In this Perspective, Smyth and Kipnis reappraise the concept of immune privilege in the central nervous system. Although immune privilege was originally thought to...
rdcu.be
May 2, 2025 at 8:07 PM
Free link below: rdcu.be/ekqtw
Reposted by Inyoung Jeong (Jung)
Liang Li and team have developed a VR system for fish to decipher how they school. The team uncovered the natural ‘control law’ used by zebrafish to coordinate behavior with others.
@icouzin.bsky.social @uni-konstanz.de @cbehav.bsky.social
Paper: www.science.org/doi/10.1126/...
@icouzin.bsky.social @uni-konstanz.de @cbehav.bsky.social
Paper: www.science.org/doi/10.1126/...
Reverse engineering the control law for schooling in zebrafish using virtual reality
Reverse engineering the control law used by schooling fish provides an effective and robust algorithm for robotic pursuit.
www.science.org
May 2, 2025 at 11:18 AM
Liang Li and team have developed a VR system for fish to decipher how they school. The team uncovered the natural ‘control law’ used by zebrafish to coordinate behavior with others.
@icouzin.bsky.social @uni-konstanz.de @cbehav.bsky.social
Paper: www.science.org/doi/10.1126/...
@icouzin.bsky.social @uni-konstanz.de @cbehav.bsky.social
Paper: www.science.org/doi/10.1126/...
I am very happy to contribute this amazing story. In this paper, I generated a genetic tool to trace CSF proteins in the brain ventricles in a noninvasive way. See below and it works very well!!
We identified to our surprise that diffusion plays a major role in distributing small proteins within the brain. See the video below showing the movement of a photoconverted secreted protein in the brain ventricle (credits to our genetic and imaging wizard @inyoungj88.bsky.social)
May 2, 2025 at 8:23 AM
I am very happy to contribute this amazing story. In this paper, I generated a genetic tool to trace CSF proteins in the brain ventricles in a noninvasive way. See below and it works very well!!
Reposted by Inyoung Jeong (Jung)
Preprint alert: 🧠🌊🦓-🐟
Have you ever wondered how molecules move around the brain?
Check out our latest preprint led by Halvor Herlyng from the team of Marie Rognes @utropstegn.bsky.social at @simularesearch.bsky.social and us at NTNU.
www.biorxiv.org/content/10.1...
Have you ever wondered how molecules move around the brain?
Check out our latest preprint led by Halvor Herlyng from the team of Marie Rognes @utropstegn.bsky.social at @simularesearch.bsky.social and us at NTNU.
www.biorxiv.org/content/10.1...
Advection versus diffusion in brain ventricular transport
Cerebrospinal fluid (CSF) is integral to brain function. CSF provides mechanical support for the brain and helps distribute nutrients, neurotransmitters and metabolites throughout the central nervous ...
www.biorxiv.org
May 2, 2025 at 7:18 AM
Preprint alert: 🧠🌊🦓-🐟
Have you ever wondered how molecules move around the brain?
Check out our latest preprint led by Halvor Herlyng from the team of Marie Rognes @utropstegn.bsky.social at @simularesearch.bsky.social and us at NTNU.
www.biorxiv.org/content/10.1...
Have you ever wondered how molecules move around the brain?
Check out our latest preprint led by Halvor Herlyng from the team of Marie Rognes @utropstegn.bsky.social at @simularesearch.bsky.social and us at NTNU.
www.biorxiv.org/content/10.1...
Reposted by Inyoung Jeong (Jung)
1/35 New paper out! @jamesTstroud and I dive into why long-term studies are crucial for understanding evolution. They reveal processes impossible to detect in short timescales and capture rare events that transform our understanding of evolutionary dynamics.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
March 19, 2025 at 7:18 PM
1/35 New paper out! @jamesTstroud and I dive into why long-term studies are crucial for understanding evolution. They reveal processes impossible to detect in short timescales and capture rare events that transform our understanding of evolutionary dynamics.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Inyoung Jeong (Jung)
New insights into neurotransmitter evolution from a GPCR screen in Trichoplax, a neuron-less animal.
with Yanez-Guerra et al.
https://www.biorxiv.org/content/10.1101/2025.04.18.649542v1
Trichoplax has tryptamine, tyramine, and phenethylamine receptors […]
[Original post on biologists.social]
with Yanez-Guerra et al.
https://www.biorxiv.org/content/10.1101/2025.04.18.649542v1
Trichoplax has tryptamine, tyramine, and phenethylamine receptors […]
[Original post on biologists.social]
April 24, 2025 at 7:05 AM
New insights into neurotransmitter evolution from a GPCR screen in Trichoplax, a neuron-less animal.
with Yanez-Guerra et al.
https://www.biorxiv.org/content/10.1101/2025.04.18.649542v1
Trichoplax has tryptamine, tyramine, and phenethylamine receptors […]
[Original post on biologists.social]
with Yanez-Guerra et al.
https://www.biorxiv.org/content/10.1101/2025.04.18.649542v1
Trichoplax has tryptamine, tyramine, and phenethylamine receptors […]
[Original post on biologists.social]
Thanks a lot for posting it, @zebrafishrock.bsky.social!!
The choroid plexus is a major cerebrospinal fluid (CSF) producing tissue in the brain.
The choroid plexus is a major cerebrospinal fluid (CSF) producing tissue in the brain.
The choroid plexus in the zebrafish brain. Credit to @inyoungj88.bsky.social. #ZebrafishZunday 🧪
April 23, 2025 at 11:40 AM
Thanks a lot for posting it, @zebrafishrock.bsky.social!!
The choroid plexus is a major cerebrospinal fluid (CSF) producing tissue in the brain.
The choroid plexus is a major cerebrospinal fluid (CSF) producing tissue in the brain.
Reposted by Inyoung Jeong (Jung)
You can learn more about the choroid plexus in this original research paper from the Jeong and the @nathaliejuya.bsky.social group: www.cell.com/cell-reports...
The evolutionarily conserved choroid plexus contributes to the homeostasis of brain ventricles in zebrafish
Jeong et al. show that the zebrafish choroid plexus has conserved anatomical features
with mammals and expresses transporters involved in cerebrospinal fluid secretion.
By using chemogenetics, they re...
www.cell.com
March 30, 2025 at 2:47 PM
You can learn more about the choroid plexus in this original research paper from the Jeong and the @nathaliejuya.bsky.social group: www.cell.com/cell-reports...
Reposted by Inyoung Jeong (Jung)
The choroid plexus in the zebrafish brain. Credit to @inyoungj88.bsky.social. #ZebrafishZunday 🧪
March 30, 2025 at 2:45 PM
The choroid plexus in the zebrafish brain. Credit to @inyoungj88.bsky.social. #ZebrafishZunday 🧪
Reposted by Inyoung Jeong (Jung)
Anatomical and Molecular Characterization of the Zebrafish Meninges https://www.biorxiv.org/content/10.1101/2025.04.09.646894v1
April 16, 2025 at 1:30 PM
Anatomical and Molecular Characterization of the Zebrafish Meninges https://www.biorxiv.org/content/10.1101/2025.04.09.646894v1
Reposted by Inyoung Jeong (Jung)
“These findings support the use of zebrafish as a useful comparative model for studying the meninges, provide a foundational description for future zebrafish meningeal research”
New work from @biomarina-vg.bsky.social & Weinstein Lab at NIH 🐟
New work from @biomarina-vg.bsky.social & Weinstein Lab at NIH 🐟
Anatomical and Molecular Characterization of the Zebrafish Meninges https://www.biorxiv.org/content/10.1101/2025.04.09.646894v1
April 16, 2025 at 4:35 PM
“These findings support the use of zebrafish as a useful comparative model for studying the meninges, provide a foundational description for future zebrafish meningeal research”
New work from @biomarina-vg.bsky.social & Weinstein Lab at NIH 🐟
New work from @biomarina-vg.bsky.social & Weinstein Lab at NIH 🐟
Reposted by Inyoung Jeong (Jung)
Have you ever wondered what role motile #cilia and cerebrospinal fluid (#CSF) play in brain development and physiology? If yes, please check out our latest article now published in Cell Reports and spearheaded by the newly minted Dr D'Gama www.sciencedirect.com/science/arti...
Motile cilia modulate neuronal and astroglial activity in the zebrafish larval brain
The brain uses a specialized system to transport cerebrospinal fluid (CSF), consisting of interconnected ventricles lined by motile ciliated ependymal…
www.sciencedirect.com
January 17, 2025 at 1:50 PM
Have you ever wondered what role motile #cilia and cerebrospinal fluid (#CSF) play in brain development and physiology? If yes, please check out our latest article now published in Cell Reports and spearheaded by the newly minted Dr D'Gama www.sciencedirect.com/science/arti...
Reposted by Inyoung Jeong (Jung)
Join us in beatiful Barcelona !!!
Save the Date and Place for the next #FENS Forum from 4-8 JULY 2026 in Barcelona, Spain!
Mark your calendars now. We look forward to welcoming you all there!🧠
loom.ly/i5LdOio
#FENS2026 #neuroscience #brain
Mark your calendars now. We look forward to welcoming you all there!🧠
loom.ly/i5LdOio
#FENS2026 #neuroscience #brain
FENS Forum 2026: Meet us in Barcelona!
From 4-8 July 2026, Barcelona will host the FENS Forum. Find out more about the host society and the #FENS2026 Programme Committee today!
loom.ly
December 9, 2024 at 6:38 PM
Join us in beatiful Barcelona !!!
Reposted by Inyoung Jeong (Jung)
Did you know: #zebrafish coined the term "crispant" in this 2016 paper (in a wink to the morpholino counterparts "morphants") #ZebrafishFunFacts 🧪
November 16, 2024 at 8:52 PM
Did you know: #zebrafish coined the term "crispant" in this 2016 paper (in a wink to the morpholino counterparts "morphants") #ZebrafishFunFacts 🧪
Reposted by Inyoung Jeong (Jung)
The movement of brain ependymal #cilia was first described by Purkinje in 1836.
Purkinje JE (1836) Ueber Flimmerbewegungen im Gehirn. Archiv für Anatomie, Physiologie und Wissenschaftliche Medicin (Müller) Jahrgang 1836, pp 289–291 […]
[Original post on biologists.social]
Purkinje JE (1836) Ueber Flimmerbewegungen im Gehirn. Archiv für Anatomie, Physiologie und Wissenschaftliche Medicin (Müller) Jahrgang 1836, pp 289–291 […]
[Original post on biologists.social]
November 13, 2024 at 12:24 PM
The movement of brain ependymal #cilia was first described by Purkinje in 1836.
Purkinje JE (1836) Ueber Flimmerbewegungen im Gehirn. Archiv für Anatomie, Physiologie und Wissenschaftliche Medicin (Müller) Jahrgang 1836, pp 289–291 […]
[Original post on biologists.social]
Purkinje JE (1836) Ueber Flimmerbewegungen im Gehirn. Archiv für Anatomie, Physiologie und Wissenschaftliche Medicin (Müller) Jahrgang 1836, pp 289–291 […]
[Original post on biologists.social]
Reposted by Inyoung Jeong (Jung)
We are hiring Group Leaders! One month left to apply ⏳ Join us in beautiful Bergen for a chance to lead exciting science in a supportive environment! 🌊
🔗 tinyurl.com/4bwn8u3n
🔗 tinyurl.com/4bwn8u3n
Group Leader Positions (Researcher I, code 1110) (270380) | University of Bergen
Job title: Group Leader Positions (Researcher I, code 1110) (270380), Employer: University of Bergen, Deadline: Sunday, December 15, 2024
tinyurl.com
November 14, 2024 at 1:32 PM
We are hiring Group Leaders! One month left to apply ⏳ Join us in beautiful Bergen for a chance to lead exciting science in a supportive environment! 🌊
🔗 tinyurl.com/4bwn8u3n
🔗 tinyurl.com/4bwn8u3n