Hayley Newton
@hayleyjnewton.bsky.social
Professor of Microbiology, Biomedicine Discovery Institute, Monash University. Admirer of intracellular bacterial pathogens, gin and coffee. Mum. She/Her.
Reposted by Hayley Newton
The pathogenic bacterium Coxiella burnetii induces the secretion of lysosomal hydrolases to the extracellular space to facilitate growth within modified phagolysosomes
@laurenbird.bsky.social @lauraem-lab.bsky.social @hayleyjnewton.bsky.social
@laurenbird.bsky.social @lauraem-lab.bsky.social @hayleyjnewton.bsky.social
Coxiella burnetii manipulates the lysosomal protease cathepsin B to facilitate intracellular success - Nature Communications
The zoonotic pathogen Coxiella burnetiiestablishes a unique intracellular niche within a lysosome-derived vacuole. Here Bird et al. undertook proteomic, cell biology and microbiology approaches to characterise this niche and the strategies employed by C. burnetii to maintain a balance between intracellular success and maintaining host cell homoeostasis.
bit.ly
July 11, 2025 at 4:53 PM
The pathogenic bacterium Coxiella burnetii induces the secretion of lysosomal hydrolases to the extracellular space to facilitate growth within modified phagolysosomes
@laurenbird.bsky.social @lauraem-lab.bsky.social @hayleyjnewton.bsky.social
@laurenbird.bsky.social @lauraem-lab.bsky.social @hayleyjnewton.bsky.social
Very proud of this story - driven by @laurenbird.bsky.social -uncovering the ways Coxiella messes with the lysosome. This has been such a fun collaboration with @lauraem-lab.bsky.social raising many new questions!
@monashuniversity.bsky.social @thedohertyinst.bsky.social @natcommag.bsky.social
@monashuniversity.bsky.social @thedohertyinst.bsky.social @natcommag.bsky.social
Excited to share this story from my PhD, out today in Nature Communications! We show that Coxiella removes cathepsin B to reduce lysosomal hostility and promote bacterial success. This depends on a vacuole established by effector CvpB.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Coxiella burnetii manipulates the lysosomal protease cathepsin B to facilitate intracellular success - Nature Communications
The zoonotic pathogen Coxiella burnetiiestablishes a unique intracellular niche within a lysosome-derived vacuole. Here Bird et al. undertook proteomic, cell biology and microbiology approaches to cha...
www.nature.com
April 25, 2025 at 6:54 AM
Very proud of this story - driven by @laurenbird.bsky.social -uncovering the ways Coxiella messes with the lysosome. This has been such a fun collaboration with @lauraem-lab.bsky.social raising many new questions!
@monashuniversity.bsky.social @thedohertyinst.bsky.social @natcommag.bsky.social
@monashuniversity.bsky.social @thedohertyinst.bsky.social @natcommag.bsky.social
Reposted by Hayley Newton
Please join us for the next ASM Hour which will be run by our Microbial Ecology and Environmental theme, and chaired by A/Prof Kate S. Howell and Dr Zahra Islam:
Theme: Microbial Magic: Nature's Cleanup Crew
Date: May 6th www.theasm.org.au/asm-hour
Theme: Microbial Magic: Nature's Cleanup Crew
Date: May 6th www.theasm.org.au/asm-hour
April 22, 2025 at 1:13 AM
Please join us for the next ASM Hour which will be run by our Microbial Ecology and Environmental theme, and chaired by A/Prof Kate S. Howell and Dr Zahra Islam:
Theme: Microbial Magic: Nature's Cleanup Crew
Date: May 6th www.theasm.org.au/asm-hour
Theme: Microbial Magic: Nature's Cleanup Crew
Date: May 6th www.theasm.org.au/asm-hour
Reposted by Hayley Newton
🦠 Job Opportunity in Microbiology! 🦠
UNSW Sydney is hiring a Lecturer/Senior Lecturer (Education Focused) in Microbiology! 🎓
📅 Apply by: March 31st, 2025: url.au.m.mimecastprotect.com/s/F9dHCRONg6...
Please share with your networks or anyone interested!
UNSW Sydney is hiring a Lecturer/Senior Lecturer (Education Focused) in Microbiology! 🎓
📅 Apply by: March 31st, 2025: url.au.m.mimecastprotect.com/s/F9dHCRONg6...
Please share with your networks or anyone interested!
LinkedIn
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lnkd.in
March 3, 2025 at 10:38 PM
🦠 Job Opportunity in Microbiology! 🦠
UNSW Sydney is hiring a Lecturer/Senior Lecturer (Education Focused) in Microbiology! 🎓
📅 Apply by: March 31st, 2025: url.au.m.mimecastprotect.com/s/F9dHCRONg6...
Please share with your networks or anyone interested!
UNSW Sydney is hiring a Lecturer/Senior Lecturer (Education Focused) in Microbiology! 🎓
📅 Apply by: March 31st, 2025: url.au.m.mimecastprotect.com/s/F9dHCRONg6...
Please share with your networks or anyone interested!
For my first Bluesky post … let me introduce you to Paracoxiella! This has been a fun adventure - shedding light on a mysterious Dot/Icm Coxiellaceae causing trouble for crayfish. A wonderful collaboration across rivers, states and oceans! www.biorxiv.org/content/10.1...
The complete genome sequence of the crayfish pathogen Candidatus Paracoxiella cheracis n.g. n.sp. provides insight into pathogenesis and the phylogeny of the Coxiellaceae family
The Coxiellaceae bacterial family, within the order Legionellales, is defined by a collection of poorly characterized obligate intracellular bacteria. The zoonotic pathogen and causative agent of huma...
www.biorxiv.org
December 3, 2024 at 9:49 PM
For my first Bluesky post … let me introduce you to Paracoxiella! This has been a fun adventure - shedding light on a mysterious Dot/Icm Coxiellaceae causing trouble for crayfish. A wonderful collaboration across rivers, states and oceans! www.biorxiv.org/content/10.1...
Thank you @asm-wa-branch.bsky.social … WAMM was a fantastic celebration of a rich and diverse microbiology community and I was thrilled to be involved!
This year at our inaugural WA Microbiology Meeting we had the pleasure of welcoming @hayleyjnewton.bsky.social from Monash Uni (@monashuniversity.bsky.social) as our esteemed Xmas Orator!
Sharing the beautiful, yet complex and multifaceted world of Coxiella that her team continues to unravel 🤩
Sharing the beautiful, yet complex and multifaceted world of Coxiella that her team continues to unravel 🤩
November 26, 2024 at 2:40 AM
Thank you @asm-wa-branch.bsky.social … WAMM was a fantastic celebration of a rich and diverse microbiology community and I was thrilled to be involved!