guiomarsolanas.bsky.social
@guiomarsolanas.bsky.social
Amazing thread on out latest preprint!!! Kudos @juliabonjoch.bsky.social
Hi Bluesky community:)

Our new manuscript is now available as a preprint!⛅️
biorxiv.org/content/10.1...

1/ Here, we describe a novel BMAL1-YAP complex in epidermal cells, which is hijacked during ageing to control the expression of up-regulated inflammation genes through enhancer binding.🧵
BMAL1 and YAP cooperate to hijack enhancers and promote inflammation in the aged epidermis
Ageing is characterised by persistent low-grade inflammation that is linked to impaired tissue homeostasis and functionality. However, the molecular mechanisms driving age-associated inflammation rema...
biorxiv.org
April 23, 2025 at 2:51 PM
🌟 Excited to share that our latest preprint is now available! We’re one step closer to understanding the complex mechanisms behind ageing and inflammation.
👉 Read the preprint here: www.biorxiv.org/cgi/content/...
Thank you to everyone who supported and believed in this project along the way!
BMAL1 and YAP cooperate to hijack enhancers and promote inflammation in the aged epidermis
Ageing is characterised by persistent low-grade inflammation that is linked to impaired tissue homeostasis and functionality. However, the molecular mechanisms driving age-associated inflammation rema...
www.biorxiv.org
April 23, 2025 at 12:47 PM