Guan-En Wun
@guanenst.bsky.social
PhD in neuroscience 🧠
Postdoc in the Pereira lab at UMass Amherst
Previously: Bieszczad lab at Rutgers, Day lab at UAB
Postdoc in the Pereira lab at UMass Amherst
Previously: Bieszczad lab at Rutgers, Day lab at UAB
Reposted by Guan-En Wun
(5/5)
🚨 It’s time to flood the zone.
NIH scientists just took a huge risk speaking out. Now it’s our turn.
📜 Read the Bethesda Declaration
✍️ Sign the Public Letter of Support
👯♀️Follow NIHers doing the work: @nihvigils.bsky.social
Read and sign here 👉 www.standupforscience.net/bethesda-dec...
🚨 It’s time to flood the zone.
NIH scientists just took a huge risk speaking out. Now it’s our turn.
📜 Read the Bethesda Declaration
✍️ Sign the Public Letter of Support
👯♀️Follow NIHers doing the work: @nihvigils.bsky.social
Read and sign here 👉 www.standupforscience.net/bethesda-dec...
www.standupforscience.net
June 9, 2025 at 12:06 PM
(5/5)
🚨 It’s time to flood the zone.
NIH scientists just took a huge risk speaking out. Now it’s our turn.
📜 Read the Bethesda Declaration
✍️ Sign the Public Letter of Support
👯♀️Follow NIHers doing the work: @nihvigils.bsky.social
Read and sign here 👉 www.standupforscience.net/bethesda-dec...
🚨 It’s time to flood the zone.
NIH scientists just took a huge risk speaking out. Now it’s our turn.
📜 Read the Bethesda Declaration
✍️ Sign the Public Letter of Support
👯♀️Follow NIHers doing the work: @nihvigils.bsky.social
Read and sign here 👉 www.standupforscience.net/bethesda-dec...
Reposted by Guan-En Wun
If you have some ~cool sounds~ and you’re okay with them being used as stimuli for research, we’re collecting natural sound recordings for a project! Bonus points if they’re sampled at 192kHz or higher 😊 send me a message if you have something like this we’d love to use it!
May 23, 2025 at 5:18 PM
If you have some ~cool sounds~ and you’re okay with them being used as stimuli for research, we’re collecting natural sound recordings for a project! Bonus points if they’re sampled at 192kHz or higher 😊 send me a message if you have something like this we’d love to use it!
Reposted by Guan-En Wun
I appreciate the offers from other scientists to help Harvard (students, labs, etc) through this attack, but what would be most helpful is for you to use your position to contact your elected representatives and make it clear this fight isn't just Harvard, it will affect you, and their districts too
May 24, 2025 at 5:47 PM
I appreciate the offers from other scientists to help Harvard (students, labs, etc) through this attack, but what would be most helpful is for you to use your position to contact your elected representatives and make it clear this fight isn't just Harvard, it will affect you, and their districts too
Reposted by Guan-En Wun
🚨 A new rule would let career scientists like NSF/NIH program officers be replaced by political appointees
Already 14,000+ public comments, deadline is Friday
📣 Comments can be short. Courts consider them—and scientists with NSF/NIH experience are especially impactful
Speak up! shorturl.at/WKuBj
Already 14,000+ public comments, deadline is Friday
📣 Comments can be short. Courts consider them—and scientists with NSF/NIH experience are especially impactful
Speak up! shorturl.at/WKuBj
May 21, 2025 at 5:39 PM
🚨 A new rule would let career scientists like NSF/NIH program officers be replaced by political appointees
Already 14,000+ public comments, deadline is Friday
📣 Comments can be short. Courts consider them—and scientists with NSF/NIH experience are especially impactful
Speak up! shorturl.at/WKuBj
Already 14,000+ public comments, deadline is Friday
📣 Comments can be short. Courts consider them—and scientists with NSF/NIH experience are especially impactful
Speak up! shorturl.at/WKuBj
Reposted by Guan-En Wun
Today, @hhmi.org stopped all competitions supporting ECRs when we needed it most.
As an FGLI undergraduate 2014/2015 HHMI EXROP participant, a 2020 Gilliam Fellow, and applicant for the now paused 2025 HGF program - I was a consistently supported by HHMI throughout my career.
Please reconsider!
As an FGLI undergraduate 2014/2015 HHMI EXROP participant, a 2020 Gilliam Fellow, and applicant for the now paused 2025 HGF program - I was a consistently supported by HHMI throughout my career.
Please reconsider!
May 16, 2025 at 10:40 PM
Today, @hhmi.org stopped all competitions supporting ECRs when we needed it most.
As an FGLI undergraduate 2014/2015 HHMI EXROP participant, a 2020 Gilliam Fellow, and applicant for the now paused 2025 HGF program - I was a consistently supported by HHMI throughout my career.
Please reconsider!
As an FGLI undergraduate 2014/2015 HHMI EXROP participant, a 2020 Gilliam Fellow, and applicant for the now paused 2025 HGF program - I was a consistently supported by HHMI throughout my career.
Please reconsider!
Feeling double whammied today with first the HHMI cancellation and now also finding out a visiting assistant professor position I applied for decided to not update me to say that I was not considered and that they filled the position after I applied.
May 16, 2025 at 8:46 PM
Feeling double whammied today with first the HHMI cancellation and now also finding out a visiting assistant professor position I applied for decided to not update me to say that I was not considered and that they filled the position after I applied.
Reposted by Guan-En Wun
Thrilled to announce that our paper is now finally out! 🎉We combine scRNAseq, 2p imaging, ephys, and behavior to understand the role of lateral septal Nts neurons in opioid withdrawal. Curious about the septum and addiction? Give it a read👇
www.cell.com/neuron/fullt...
www.cell.com/neuron/fullt...
Opioid-driven disruption of the septum reveals a role for neurotensin-expressing neurons in withdrawal
Opioid withdrawal produces a dysphoric state that can lead to relapse. Simon et al.
reveal that lateral septal neurotensin-expressing neurons are selectively activated
by naloxone and drive changes in...
www.cell.com
May 16, 2025 at 3:39 PM
Thrilled to announce that our paper is now finally out! 🎉We combine scRNAseq, 2p imaging, ephys, and behavior to understand the role of lateral septal Nts neurons in opioid withdrawal. Curious about the septum and addiction? Give it a read👇
www.cell.com/neuron/fullt...
www.cell.com/neuron/fullt...
Just received an email stating that all applications for the 2025 HHMI Hanna Gray fellowship. Truly a bummer in funding news for science today.
May 16, 2025 at 5:54 PM
Just received an email stating that all applications for the 2025 HHMI Hanna Gray fellowship. Truly a bummer in funding news for science today.
Reposted by Guan-En Wun
My trainee's F31 diversity from NIDDK "terminated" today. We received a NGA for $0.00.
He worked his butt off for it and would have been competitive in the normal F31 pool. This is just blatant discrimination. If there are large lawsuits being put together, please share that info. #contractlaw
He worked his butt off for it and would have been competitive in the normal F31 pool. This is just blatant discrimination. If there are large lawsuits being put together, please share that info. #contractlaw
All NIDA F31 diversity scholars officially losing their funding...
I barely have words.
Expected at this point but so so disappointing and unfair. We are effectively punishing some of America's best science students for telling the government they are from an underrepresented community.
I barely have words.
Expected at this point but so so disappointing and unfair. We are effectively punishing some of America's best science students for telling the government they are from an underrepresented community.
April 30, 2025 at 1:44 PM
My trainee's F31 diversity from NIDDK "terminated" today. We received a NGA for $0.00.
He worked his butt off for it and would have been competitive in the normal F31 pool. This is just blatant discrimination. If there are large lawsuits being put together, please share that info. #contractlaw
He worked his butt off for it and would have been competitive in the normal F31 pool. This is just blatant discrimination. If there are large lawsuits being put together, please share that info. #contractlaw
Reposted by Guan-En Wun
Bone chilling.
A court ordered Kilmar Abrego Garcia to stay in the United States.
The Supreme Court ruled 9-0 that he was illegally removed. Trump is pretending he won the ruling 9-0.
1/ You may not think this case means anything to you. But let me tell you why it does.
A court ordered Kilmar Abrego Garcia to stay in the United States.
The Supreme Court ruled 9-0 that he was illegally removed. Trump is pretending he won the ruling 9-0.
1/ You may not think this case means anything to you. But let me tell you why it does.
April 14, 2025 at 9:04 PM
Bone chilling.
A court ordered Kilmar Abrego Garcia to stay in the United States.
The Supreme Court ruled 9-0 that he was illegally removed. Trump is pretending he won the ruling 9-0.
1/ You may not think this case means anything to you. But let me tell you why it does.
A court ordered Kilmar Abrego Garcia to stay in the United States.
The Supreme Court ruled 9-0 that he was illegally removed. Trump is pretending he won the ruling 9-0.
1/ You may not think this case means anything to you. But let me tell you why it does.
Reposted by Guan-En Wun
A nice, layperson writeup of my latest work, which is now out on eLife!
TLDR: Using snRNA-seq, we find cell type abundance differences and sex-biased gene expression differences that may explain innate differences in mating + parenting behavior
elifesciences.org/digests/1031...
TLDR: Using snRNA-seq, we find cell type abundance differences and sex-biased gene expression differences that may explain innate differences in mating + parenting behavior
elifesciences.org/digests/1031...
The parenting styles of deer mice
Single-nuclei RNA-sequencing sheds new light on how two closely related species of deer behave differently when mating and caring for young.
elifesciences.org
April 10, 2025 at 2:54 PM
A nice, layperson writeup of my latest work, which is now out on eLife!
TLDR: Using snRNA-seq, we find cell type abundance differences and sex-biased gene expression differences that may explain innate differences in mating + parenting behavior
elifesciences.org/digests/1031...
TLDR: Using snRNA-seq, we find cell type abundance differences and sex-biased gene expression differences that may explain innate differences in mating + parenting behavior
elifesciences.org/digests/1031...
Reposted by Guan-En Wun
I just learned that there's a national graduate student crisis line - gradresources.org. Might be worth spreading the word as I'm pretty sure exactly *checks notes* zero grad students are doing well emotionally right now.
Grad Resources
Encouraging and equipping graduate students for impact.
gradresources.org
April 3, 2025 at 4:19 AM
I just learned that there's a national graduate student crisis line - gradresources.org. Might be worth spreading the word as I'm pretty sure exactly *checks notes* zero grad students are doing well emotionally right now.
Reposted by Guan-En Wun
If you or someone you know has been negatively affected by NIH-funded clinical trials being paused, disrupted, cancelled etc., I have a contact with the Senate HELP Committee eager to collect stories of everyday Americans affected by the NIH closures. Please DM me.
April 4, 2025 at 11:20 AM
If you or someone you know has been negatively affected by NIH-funded clinical trials being paused, disrupted, cancelled etc., I have a contact with the Senate HELP Committee eager to collect stories of everyday Americans affected by the NIH closures. Please DM me.
Reposted by Guan-En Wun
Happy to share that the Max Planck postdoc program officially launched!
I was lucky to be part of the committee that designed the program - our goal was to provide better and more structured resources for onboarding, career development, & mentoring.
I was lucky to be part of the committee that designed the program - our goal was to provide better and more structured resources for onboarding, career development, & mentoring.
🚀 Apply now 🚀
The new Max Planck #Postdoc Program offers a guaranteed contract of at least 3 years, targeted mentoring, and career workshops.
postdocprogram.mpg.de
#ScienceCareer #PostdocProgram
The new Max Planck #Postdoc Program offers a guaranteed contract of at least 3 years, targeted mentoring, and career workshops.
postdocprogram.mpg.de
#ScienceCareer #PostdocProgram
April 1, 2025 at 2:01 PM
Happy to share that the Max Planck postdoc program officially launched!
I was lucky to be part of the committee that designed the program - our goal was to provide better and more structured resources for onboarding, career development, & mentoring.
I was lucky to be part of the committee that designed the program - our goal was to provide better and more structured resources for onboarding, career development, & mentoring.
Reposted by Guan-En Wun
'The results show that mitochondria, which generate the energy that powers cells, differ in type and density in different parts of the brain. For example, the evolutionarily oldest brain regions have a lower density of mitochondria than newer regions.'
www.nature.com/articles/d41...
www.nature.com/articles/d41...
First map of human brain mitochondria is ‘groundbreaking’ achievement
Hundreds of cubes of human brain tissue help scientists to chart the energy-making capabilities of various brain regions.
www.nature.com
March 30, 2025 at 9:16 AM
'The results show that mitochondria, which generate the energy that powers cells, differ in type and density in different parts of the brain. For example, the evolutionarily oldest brain regions have a lower density of mitochondria than newer regions.'
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Reposted by Guan-En Wun
every zoom meeting can be a mukbang if you put your mind to it
March 30, 2025 at 6:34 PM
every zoom meeting can be a mukbang if you put your mind to it
Reposted by Guan-En Wun
Dynamic Ontogeny of Auditory Lateralization in the Zebra Finch https://www.biorxiv.org/content/10.1101/2025.03.30.646178v1
March 31, 2025 at 12:15 PM
Dynamic Ontogeny of Auditory Lateralization in the Zebra Finch https://www.biorxiv.org/content/10.1101/2025.03.30.646178v1
Reposted by Guan-En Wun
Defending soon? Come postdoc with us - MUSC is a great place to prepare you for your next career move, in or outside of academia!
The Charleston Alcohol Research Center has an opening for a #postdoctoral fellowship on the #NIAAA T32 training grant - please spread the word and contact me if interested in working in beautiful Charleston, SC @drjrink.bsky.social
March 20, 2025 at 6:58 PM
Defending soon? Come postdoc with us - MUSC is a great place to prepare you for your next career move, in or outside of academia!
Reposted by Guan-En Wun
Explore the newly launched Early-Career Neuroscientists Resource Center, designed to help you navigate the field with news, expert insights and practical tools. The page also highlights job openings, seminars, and more:
#neuroskyence
www.thetransmitter.org/early-career...
#neuroskyence
www.thetransmitter.org/early-career...
Early-Career Neuroscientists Resource Center
News, perspectives and resources to help navigate the early stages of your neuroscience career
www.thetransmitter.org
March 20, 2025 at 9:12 PM
Explore the newly launched Early-Career Neuroscientists Resource Center, designed to help you navigate the field with news, expert insights and practical tools. The page also highlights job openings, seminars, and more:
#neuroskyence
www.thetransmitter.org/early-career...
#neuroskyence
www.thetransmitter.org/early-career...
Reposted by Guan-En Wun
A comprehensive review on covalent chemical strategies for protein self-labeling from @kjohnsson.bsky.social's lab: HaloTag, SNAP-tag et al. www.annualreviews.org/content/jour...
March 20, 2025 at 8:56 PM
A comprehensive review on covalent chemical strategies for protein self-labeling from @kjohnsson.bsky.social's lab: HaloTag, SNAP-tag et al. www.annualreviews.org/content/jour...
First hike of the season and since we moved to Western Mass! Weather was nice so had to take advantage of it even if the trail was muddy and slippery in some steep parts.
March 16, 2025 at 5:35 PM
First hike of the season and since we moved to Western Mass! Weather was nice so had to take advantage of it even if the trail was muddy and slippery in some steep parts.
Livid because one of my students who has worked their ass off has had a graduate school admission offer rescinded due to anticipated budget cuts. We’re already seeing the next generation of scientists being stopped from achieving their goals thanks to the federal administration.
March 13, 2025 at 11:17 AM
Livid because one of my students who has worked their ass off has had a graduate school admission offer rescinded due to anticipated budget cuts. We’re already seeing the next generation of scientists being stopped from achieving their goals thanks to the federal administration.
Two months into this postdoc and two grant applications submitted! It’s been tough developing a research plan in an unfamiliar field in just a few weeks but I’m glad to know I can do it. And now I have a way better understanding of maternal behavior than I did before!
March 4, 2025 at 2:57 AM
Two months into this postdoc and two grant applications submitted! It’s been tough developing a research plan in an unfamiliar field in just a few weeks but I’m glad to know I can do it. And now I have a way better understanding of maternal behavior than I did before!