@gstaiger.bsky.social
Reposted
Chemical proteomics decrypts the kinases that shape the dynamic human phosphoproteome https://www.biorxiv.org/content/10.1101/2025.11.18.689017v1
November 18, 2025 at 11:03 PM
Chemical proteomics decrypts the kinases that shape the dynamic human phosphoproteome https://www.biorxiv.org/content/10.1101/2025.11.18.689017v1
Reposted
The appearance of large language models caused a drastic shift in the vocabulary of academic writing, according to an analysis in #ScienceAdvances of more than 15 million biomedical abstracts published from 2010 to 2024. scim.ag/3IhpoQF
Delving into LLM-assisted writing in biomedical publications through excess vocabulary
Excess words track LLM usage in biomedical publications.
scim.ag
July 9, 2025 at 7:01 PM
The appearance of large language models caused a drastic shift in the vocabulary of academic writing, according to an analysis in #ScienceAdvances of more than 15 million biomedical abstracts published from 2010 to 2024. scim.ag/3IhpoQF
Reposted
This rate of validation suggests that affinity reagents such as antibodies should be considered non-specific until proven otherwise:
357 validated antibodies out of 1,124 tested.
.
357 validated antibodies out of 1,124 tested.
.
June 25, 2025 at 7:42 PM
This rate of validation suggests that affinity reagents such as antibodies should be considered non-specific until proven otherwise:
357 validated antibodies out of 1,124 tested.
.
357 validated antibodies out of 1,124 tested.
.
Reposted
Error control in proteomics mass spectrometry analysis is hard. We came up with a way to evaluate error control. Upshot: for old-school DDA data, not so bad. For DIA data, no existing tool successfully controls the false discovery rate!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Assessment of false discovery rate control in tandem mass spectrometry analysis using entrapment - Nature Methods
A theoretical foundation for entrapment methods is presented, along with a method that enables more accurate evaluation of false discovery rate (FDR) control in proteomics mass spectrometry analysis p...
www.nature.com
June 16, 2025 at 8:57 PM
Error control in proteomics mass spectrometry analysis is hard. We came up with a way to evaluate error control. Upshot: for old-school DDA data, not so bad. For DIA data, no existing tool successfully controls the false discovery rate!
www.nature.com/articles/s41...
www.nature.com/articles/s41...