The third EM structure of a Bfu type bifurcating complex coming out of the Adams - Li collaboration. Wor-Bfu is a cool W containing complex that can detoxify aldehydes and found in a number of gut organisms. It is our third article in PNAS on W in the gut microbiome🧪
www.pnas.org/doi/10.1073/...

After a long time of trying, finally a structure of the NADP(H) dependent NiFe hydrogenase from Pyrococcus furious. 🧪
kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...

Characterization of a W storage protein. Illustrating the importance of W in the gut 🧪
Shao N, Storage of the vital metal tungsten in a dominant SCFA-producing human gut microbe Eubacterium limosum and implications for other gut microbes. mBio0:e02605-24.https://doi.org/10.1128/mbio.02605-24

#2 out of 3 bfu family bifurcating structure with our CryoEM collaborators.
Cryo-EM Structures Define the Electron Bifurcating Flavobicluster and Ferredoxin Binding Site in an Archaeal Nfn-Bfu Transhydrogenase - Journal of Biological Chemistry www.jbc.org/article/S002...

The first of a series of 3 cryoEM structures from our collaborative efforts is shedding some light in the Bfu type electron bifurcating complexes. The Bfu type bifurcating complexes utilize a combination of flavin and iron sulfur clusters to bifurcate electron pairs.
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A simple Tungsten and molybdenum assay for biological samples. Excellent work by an UGA undergraduate student. 🧪
bio-protocol.org/en/bpdetail?...

Tungsten enzymes and lactate metabolism in the human gut microbiome. 🧪
www.pnas.org/doi/10.1073/...

Tungsten as a trace element for the human microbiome 🧪
www.pnas.org/doi/full/10....

www.pnas.org/doi/10.1073/...