Siegfried Gessulat
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gessulat.bsky.social
Siegfried Gessulat
@gessulat.bsky.social
Head of Machine Learning at MSAID ✨
Computational proteomics 💻🔬 He/him

Reposted by Siegfried Gessulat
Hello #ASMS2025! Get ready for two exciting presentations from our team in Baltimore — happening tomorrow!

🔗 msaid.de/conferences/...
📍 Stop by Booth #203

#TeamMassSpec #TeamProteomics #Proteomics #MassSpectrometry
June 2, 2025 at 9:30 PM
Reposted by Siegfried Gessulat
#TeamMassSpec, don't miss my talk about double dipping in DIA data analysis on Tuesday afternoon at #ASMS2025! It's not as savoury as the one below, but will contain a couple of spicy takes. 🙃
May 31, 2025 at 5:04 PM
🧵1/5 Although I'll miss #ASMS2025 I'm hugely excited about @lizimamisashvili.bsky.social's oral 🕵️‍♀️ TOE am 09:50. Inferys 5 is our biggest ML update in years. We support any PTM input in principle, dramatically increase speed, and add support TimsTOF. All with a single model.
May 30, 2025 at 2:43 PM
Reposted by Siegfried Gessulat
We are working hard on generalizing our peptide property prediction models to more diverse peptide classes! Watch out for my colleague @lizimamisashvili.bsky.social's ASMS talk (TOE am) to input any molecular structure to our models. Next, we need to generalize our model output too.
April 23, 2025 at 8:37 AM
Reposted by Siegfried Gessulat
Thanks for bringing this to our attention - this is caused by Met-containing peptides in the LFQ Benchmark DIA files. We state in the Methods that we filter these out, but in E10-C they slipped through. We fixed this and quantification now looks as expected (github.com/msaid-de/chi...)
April 23, 2025 at 1:21 PM
Reposted by Siegfried Gessulat
A really solid paper from the MSAID team.
I’d guess there’s 30 minutes worth of information in the supplementary alone (check out the discussion).
Covers many aspects of spectrum-centric proteomics and why it’s the best single approach for DDA, DIA, and PRM data.
🚨 New in @naturemethods.bsky.social
#CHIMERYS has already transformed #proteomics since 2022, powering DDA, DIA & PRM analysis in a single workflow.
Wanna know how CHIMERYS works? 👉 www.nature.com/articles/s41...
#TeamMassSpec #NatureMethods #ASMS2025 🧪🔬
1/7
April 22, 2025 at 11:22 AM
Reposted by Siegfried Gessulat
I am happy that our first publication showcasing the MSAID Platform is out! Read all about its unique features or try it for free at platform.msaid.io!
February 25, 2025 at 11:21 AM