Gareth Ball
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garedaba.bsky.social
Gareth Ball
@garedaba.bsky.social
230 followers 310 following 31 posts
Neurodevelopmental Modelling @ MCRI in Melbourne. Early brain development, neuroscience, ML.
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Reposted by Gareth Ball
biorxiv-neursci.bsky.social
A spatial transcriptomic atlas of autism-associated genes identifies convergence in the developing human thalamus https://www.biorxiv.org/content/10.1101/2025.11.05.685843v1
November 6, 2025 at 11:16 PM
Reposted by Gareth Ball
gozziale.bsky.social
🚨 Excited to share the latest preprint form the lab ➡️https://tinyurl.com/32d3be9f

Here we tackle a long-standing chicken-or-egg 🐣🥚question in #autism and developmental neuroscience

➡️ Is excitation–inhibition (E:I) imbalance a "cause" or a "consequence" of #autism?

Check out what we found!
🧵1/n
September 10, 2025 at 3:08 PM
Reposted by Gareth Ball
biorxiv-neursci.bsky.social
Multimodal imaging of human fetal brain development at the mesoscopic scale using 11.7 T ex vivo MRI https://www.biorxiv.org/content/10.1101/2025.09.08.669657v1
September 9, 2025 at 4:15 AM
Reposted by Gareth Ball
alexfornito.bsky.social
🔥ATTENTION!🔥

Registration for the 2026 Noosa Brain Workshop is now open!

Join us for some amazing science, sun, and surf in one of Australia's most beautiful beach towns.

Details:
tinyurl.com/arbc5pp6

Check out or incredible list of confirmed speakers. More to come...
September 5, 2025 at 1:29 AM
Reposted by Gareth Ball
biorxiv-neursci.bsky.social
Expanding canonical cortical cell type markers in the era of single-cell transcriptomics https://www.biorxiv.org/content/10.1101/2025.08.26.672469v1
August 27, 2025 at 8:15 AM
Reposted by Gareth Ball
debbysilver.bsky.social
Sharing our newest study led by the incredibly talented @federicamosti.bsky.social investigating new molecular mechanisms of human brain development. We discover a human-specific enhancer HAR1984 that influences chromatin looping to promote cortical size and folding! www.biorxiv.org/cgi/content/...
August 10, 2025 at 1:19 PM
Reposted by Gareth Ball
wiringthebrain.bsky.social
Spatial transcriptomics reveals human cortical layer and area specification www.nature.com/articles/s41... - early emergence of layers; graded differentiation along A/P axis, w/ early, sharp V1/V2 boundary
Spatial transcriptomics reveals human cortical layer and area specification - Nature
Multiplexed error-robust fluorescence in situ hybridization (MERFISH) together with deep-learning-based nucleus segmentation enabled the construction of a highly detailed and informative spatially res...
www.nature.com
August 8, 2025 at 8:13 AM
Reposted by Gareth Ball
garedaba.bsky.social
JOB ALERT! We're seeking a postdoctoral scientist to join Developmental Imaging at @mcri.bsky.social in Melbourne.

Role will involve working with international partners on a new project charting brain growth in children with NF-1

Please reach out for more information

www.seek.com.au/job/86090834
Research Officer Job in Parkville, Melbourne VIC - SEEK
We are seeking a Postdoctoral Research Officer to drive international neuroimaging research into childhood NF1 brain development.
www.seek.com.au
July 29, 2025 at 11:44 PM
garedaba.bsky.social
JOB ALERT! We're seeking a postdoctoral scientist to join Developmental Imaging at @mcri.bsky.social in Melbourne.

Role will involve working with international partners on a new project charting brain growth in children with NF-1

Please reach out for more information

www.seek.com.au/job/86090834
Research Officer Job in Parkville, Melbourne VIC - SEEK
We are seeking a Postdoctoral Research Officer to drive international neuroimaging research into childhood NF1 brain development.
www.seek.com.au
July 29, 2025 at 11:44 PM
garedaba.bsky.social
Big fan of acronyms
biorxiv-neursci.bsky.social bioRxiv Neuroscience @biorxiv-neursci.bsky.social · Jul 25
TRAMFIX: TRavelling Across Melbourne for FIXel-based analysis (a reproducibility study) https://www.biorxiv.org/content/10.1101/2025.07.21.666058v1
July 26, 2025 at 4:08 AM
Reposted by Gareth Ball
bttyeo.bsky.social
1/11 Excited to share our @Naturestudy led by @leonooi.bsky.social @csabaorban.bsky.social @shaoshiz.bsky.social

AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements...

doi.org/10.1038/s415...
July 17, 2025 at 1:36 AM
Reposted by Gareth Ball
natneuro.nature.com
Human thalamocortical connectivity matures along the cortex’s sensorimotor–association axis

www.nature.com/articles/s41...
Human thalamocortical structural connectivity develops in line with a hierarchical axis of cortical plasticity - Nature Neuroscience
Sydnor et al. developed a new tractography atlas of thalamocortical structural connections and applied it to three youth samples. They uncovered coordinated development between thalamic connectivity a...
www.nature.com
July 7, 2025 at 4:52 PM
Reposted by Gareth Ball
bertogliolab.bsky.social
A mouse brain stereotaxic topographic atlas with isotropic 1-μm resolution
www.nature.com/articles/s41...
A mouse brain stereotaxic topographic atlas with isotropic 1-μm resolution - Nature
A stereotaxic atlas of the whole mouse brain, based on a Nissl-stained cytoarchitecture dataset with isotropic 1-μm resolution, achieved through continuous micro-optical sectioning tomography, promise...
www.nature.com
July 2, 2025 at 4:27 PM
Reposted by Gareth Ball
tsyporin.bsky.social
Thrilled to present MIND!

A model for how the sensorimotor–association axis of the neocortex develops.

Huge thanks to the incredible multidisciplinary team who made this happen.

www.biorxiv.org/content/10.1...
Competing Programs Shape Cortical Sensorimotor-Association Axis Development
The neocortex is organized along a dominant sensorimotor-to-association (S-A) axis, anchored by modality-specific primary sensorimotor areas at one end and transmodal association areas that form distr...
www.biorxiv.org
July 1, 2025 at 5:29 PM
Reposted by Gareth Ball
zhiqiangsha.bsky.social
Addressing artifactual bias in large, automated MRI analyses of brain development | Nature Neuroscience
www.nature.com/articles/s41...
Addressing artifactual bias in large, automated MRI analyses of brain development - Nature Neuroscience
As large-scale neurodevelopmental MRI studies gain prominence, the authors identify tradeoffs between sample size and quality control that can dramatically affect results, and they evaluate a range of...
www.nature.com
July 2, 2025 at 12:12 AM
Reposted by Gareth Ball
stuartoldham.bsky.social
On Friday/Saturday I have a poster (1205) on our work using generative network models, where I explore how heterochronous spatial gradients constrain brain connectivty 🧠⌛🏳️‍🌈 Also Saturday (11:30am; Great Hall) I have a talk on this work, so make sure you have recovered from club night in time for it!
June 25, 2025 at 3:13 AM
Reposted by Gareth Ball
stuartoldham.bsky.social
For those at OHBM, check out my posters and talk! Today and tomorrow I (and maybe @garedaba.bsky.social) will be presenting my poster (1012) on our work linking fetal gene expression to neonatal connectome organisation 🧬🧠👶🌐 1/2 #OHBM #OHBM2025 (preprint here www.biorxiv.org/content/10.1... )
June 25, 2025 at 3:13 AM
Reposted by Gareth Ball
biorxiv-neursci.bsky.social
Accurate spatial localization of Allen Human Brain Atlas gene expression data for human neuroimaging https://www.biorxiv.org/content/10.1101/2025.06.02.656812v1
June 4, 2025 at 6:15 AM
Reposted by Gareth Ball
biorxiv-neursci.bsky.social
Macroscale Connectivity in the Octopus brain https://www.biorxiv.org/content/10.1101/2025.05.28.656524v1
May 29, 2025 at 6:17 AM
Reposted by Gareth Ball
stuartoldham.bsky.social
Do you like brain network hubs?🧠🌐✳️Do you like genes?🧬What about neurodevelopment?👶What if I told you the latest work by @garedaba.bsky.social and myself combined all of these?🤯🤯🤯

See Gareth's thread for a primer of our findings, then read the paper for the details!
www.biorxiv.org/content/10.1...
May 28, 2025 at 6:10 AM
garedaba.bsky.social
New preprint with @stuartoldham.bsky.social
biorxiv-neursci.bsky.social bioRxiv Neuroscience @biorxiv-neursci.bsky.social · May 27
Transcriptomic divergence of network hubs in the prenatal human brain https://www.biorxiv.org/content/10.1101/2025.05.26.656237v1
May 28, 2025 at 5:17 AM
Reposted by Gareth Ball
antjehellwich.bsky.social
DL-SAMER: A new deep learning + retrospective motion correction method for fast, motion-robust 3D brain #MRI — effective even in challenging pediatric cases.
Check it out 👉 marketing.webassets.siemens-healthineers.com/7a1c195a6a39...

#NeuroSky #RadSky #MagnetomWorld
@harvardmed.bsky.social
Integrating SAMER Retrospective Motion Correction into 3D Deep Learning Image Reconstruction for High-Quality, Fast, and Robust Brain MRI by Daniel Polak (Siemens Healthineers, Erlangen, Germany), et al. Patient motion is one of the most common sources of image degradation in clinical neuroimaging, manifesting as blurring, ringing, or in severe cases ghosting/folding artifacts. Radiologists are often forced to either interpret images despite these artifacts – risking missed or misinterpreted pathologies – or to request costly and time-consuming repeat scans. In pediatric patients, motion is typically more severe, often necessitating anesthesia, which increases both procedural risks and costs. Motion artifacts also reduce the reliability of automated quantitative clinical tools, such as those used for brain morphometry and the identification or segmentation of hemorrhages, edema, and tumors. Such tools are increasingly important in the screening, monitoring, and treatment of neurodegenerative diseases such as Alzheimer’s. Scout Accelerated Motion Estimation and Reduction (SAMER) is a retrospective motion correction technique for brain imaging that enables fast motion estimation and artifact correction without the need for external tracking hardware. Clinically evaluated in both adult and pediatric patient populations, SAMER has significantly reduced the number of non-diagnostic motion cases. More recently, SAMER has been integrated into a deep learning-based image reconstruction framework to support highly accelerated, motion-robust 3D brain imaging. In this article, the authors review the combined DL-SAMER technique and demonstrate its effectiveness in vivo using MPRAGE and SPACE acquisitions at R = 6 acceleration. Shout out to the co-authors: Dominik Nickel, Daniel Nicolas Splitthoff, Bryan Clifford, Yan Tu Huang, Wei-Ching Lo, Shohei Fujita, Susie Y. Huang, John Conklin, Lawrence L. Wald, Stephen Cauley
May 22, 2025 at 8:30 AM
Reposted by Gareth Ball
biorxiv-neursci.bsky.social
Differential patterns of cortical expansion in fetal and preterm brain development https://www.biorxiv.org/content/10.1101/2025.05.19.653958v1
May 21, 2025 at 8:15 PM
Reposted by Gareth Ball
aitormg.bsky.social
New preprint alert 📣📣📣

New results showing how strong the link between brain dynamics and structure is 💫👀🧪

"Spontaneous spiking statistics form unique area-specific fingerprints and reflect the hierarchy of cerebral cortex" 🐾🧠
www.biorxiv.org/content/10.1...
Spontaneous spiking statistics form unique area-specific fingerprints and reflect the hierarchy of cerebral cortex
The cerebral cortex, from sensory to higher cognitive areas, is hierarchically organised Several dynamical and anatomical measures, such as timescales and neurotransmitter receptor expression, have in...
www.biorxiv.org
May 15, 2025 at 11:36 AM
Reposted by Gareth Ball
qianxuyu.bsky.social
Today in @nature.com , we report a spatial single-cell atlas of human cortical development, revealing surprisingly early specification of human cortical layers and areas.
We built an interactive browser to explore the spatial data: walshlab.org/research/cor...
Paper link below 👇
May 14, 2025 at 5:24 PM