Felix Mikus
LightNews LightNews
banner
fmikus.bsky.social
Felix Mikus
@fmikus.bsky.social
590 followers 530 following 27 posts
Postdoc @Dudin lab, UNIGE
Previously EMBL HD

Lots of microscopy of all different things. If it’s not big enough, make it bigger #UExM


Views my own
Posts Replies Media Videos
Reposted by Felix Mikus
clairedeo.bsky.social
New preprint 🥳! We made photoclickable HaloTag ligands to precisely control protein labeling on living cells. With it, we can do some cool multicolor stuff. Huge congrats to Franzi and all co-authors! Check it out 👇

www.biorxiv.org/content/10.1...
November 13, 2025 at 4:20 PM
Reposted by Felix Mikus
fburki.bsky.social
It is a collaboration between my lab (Uppsala U) and the labs of @dudinlab.bsky.social (Geneva U) and @filiphusnik.bsky.social (OIST). More info and how to apply here:
uu.varbi.com/en/what:job/.... (The use of AI for writing the motivation letter is discouraged and will be regarded unfavourably) 2/2
PhD student in systematic biology
The Department of Organismal Biology teaches and explores the evolution, development and function on the organismal level. For more information see Department of Organismal Biology - Uppsala Universit
uu.varbi.com
November 12, 2025 at 9:50 AM
Reposted by Felix Mikus
bioarm.bsky.social
This is a glimpse of the cytoskeletal structures we found doing U-ExM in more than 200 species, now in Cell🤩: shorturl.at/6oHvi
Amazing collaboration between @centriolelab.bsky.social , @dudinlab.bsky.social and @gautamdey.bsky.social labs.
I believe last one is a 🕷️
#FluorescenceFriday
#Microscopy
November 7, 2025 at 1:35 PM
Reposted by Felix Mikus
embl.org
(1/2) A new study from EMBL researchers and their collaborators provides unprecedented insights into the cellular architecture of over 200 species of plankton – tiny but ecologically critical marine organisms – using ultrastructure expansion microscopy.

Learn more: www.cell.com/cell/fulltex...
November 4, 2025 at 8:30 AM
Reposted by Felix Mikus
pilhoferlab.bsky.social
🥳 Today marks the start of the lab of former postdoc @florianwollweber.bsky.social at @embl.org Grenoble!
www.embl.org/groups/wollw...
Florian-- we will miss you dearly and wish you much success!

With us, Florian applied multiscale imaging 🔬to Asgard archaea ...👇
November 1, 2025 at 12:41 PM
Reposted by Felix Mikus
olivierduss.bsky.social
Excited to share my first PhD student’s @biorxivpreprint.bsky.social!

Tracking 5 dyes simultaneously Kavan Gor @embl.org tracks nascent #RNA folding during #ribosome assembly to correlate structural with functional information on single RNA molecules!

Check it out!

www.biorxiv.org/content/10.1...
November 1, 2025 at 5:56 AM
Reposted by Felix Mikus
floravincent.bsky.social
Exciting day for the lab: our 1rst paper is officially out in @currentbiology.bsky.social 🥳 Wonderful collaboration wt @gautamdey.bsky.social showing how Cryo-ExM achieves consistent immunostaining in diverse diatoms, from the lab and the natural environment 1/n
#ProtistsOnSky
tinyurl.com/2zxaund7
October 31, 2025 at 3:27 PM
Reposted by Felix Mikus
dudinlab.bsky.social
Our new #ExÂME effort with the @moorefound.bsky.social, is scaling up with T. Richards & @gautamdey.bsky.social : antibody screens, optimized protocols, open-access imaging, and community training--> all toward a shared atlas.

👉 Join us: www.dudinlab.com
#ProtistsOnSky #CellBiology #Evolution
October 31, 2025 at 2:42 PM
Reposted by Felix Mikus
dudinlab.bsky.social
And it’s a double feature, as shown by @gautamdey.bsky.social ial & @floravincent.bsky.social for the sturdy #Diatoms! Also out today in @currentbiology.bsky.social 🌊

www.cell.com/current-biol...
Diatom ultrastructural diversity across controlled and natural environments
Flori et al. establish high-resolution and generalizable immunofluorescence in cultured and environmental diatoms, thanks to 4-fold cryo-expansion microscopy. This represents a step-change for compara...
www.cell.com
October 31, 2025 at 2:42 PM
Reposted by Felix Mikus
dudinlab.bsky.social
🚨Our collaboration with @centriolelab.bsky.social & @gautamdey.bsky.social is out today in @cp-cell.bsky.social
We show that #Expansion #Microscopy is a broad-spectrum modality for Euks, enabling 3D phenotypic maps rooted to phylogeny.
#ProtistsOnSky #SciComm #SciSky

www.cell.com/cell/fulltex...
October 31, 2025 at 2:42 PM
Reposted by Felix Mikus
tsbschm.bsky.social
Great to see this finally published!

Metalog: curated and harmonised contextual data for global metagenomics samples

now out in @narjournal.bsky.social

academic.oup.com/nar/advance-...
Metalog: curated and harmonised contextual data for global metagenomics samples
Abstract. Metagenomic sequencing enables the in-depth study of microbes and their functions in humans, animals, and the environment. While sequencing data
academic.oup.com
October 31, 2025 at 3:16 PM
fmikus.bsky.social
Trip 3 and past the 100 species count! Thank you for hosting us in České Budějovice Julius and Galina (and everyone providing samples!), for the prime support, and a fantastic selection of cultures!
#expandthemall @moorefound.bsky.social @dudinlab.bsky.social @gautamdey.bsky.social & T. Richards
Marine doing the heavy lifting and transporting a dry shipper with many plunge frozen samples
October 9, 2025 at 11:29 AM
Reposted by Felix Mikus
centriolelab.bsky.social
Trouble imaging actin in ExM? Meet HAK-Actin, a probe for U-ExM, cryo-ExM & iU-ExM. Enables post-expansion labeling for max signal. www.biorxiv.org/content/10.1...
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social
August 28, 2025 at 7:03 AM
Reposted by Felix Mikus
kristina-prokina.bsky.social
New paper is out! We have studied the cute tiny Discocelia plataet sp. n. to obtain the first molecular data of the order Discocelida and clarify its cell structure. All this for a better understanding of the evolution of Cercozoa.

onlinelibrary.wiley.com/doi/epdf/10....
August 26, 2025 at 4:54 PM
Reposted by Felix Mikus
blarson.bsky.social
What could be more exciting than watching Euplotes scurry around under the microscope? How about adding some raptorial predation by supergiant cannibal cells?

www.biorxiv.org/content/10.1...

Video by Vittorio Boscaro.

1/n
August 26, 2025 at 8:56 PM
Reposted by Felix Mikus
gautamdey.bsky.social
Want to help us image and understand those incredible samples Felix just collected at UBC - and many more?

2 more days to apply!

embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

#ExM #PlanetaryCellBiology

🧪🧬🔬🌍🌱🦠
August 22, 2025 at 7:58 PM
fmikus.bsky.social
Two weeks at @ubcbotany.bsky.social are coming to an end, marking the 2nd trip for our @moorefound.bsky.social project @dudinlab.bsky.social @gautamdey.bsky.social & T. Richards.
Thanks for hosting @pjkeelinglab.bsky.social, @fburki.bsky.social and most importantly Denis Tikhonenkov & Vittorio!
Nicole, Anthony, and myself looking at expanded fireworm samples - not staged at all
August 22, 2025 at 5:27 PM
Reposted by Felix Mikus
dudinlab.bsky.social
Join our crazy beautiful project of ExM Atlas !
One more position to fill, this time for a Research Technician at @embl.org in @gautamdey.bsky.social lab.

Come have fun with us !.
gautamdey.bsky.social Gautam Dey @gautamdey.bsky.social · Aug 7
Want to acquire #ExM images like this and help us understand the true extent of cytoskeletal diversity across the tree of life? This position might be for you!

embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

With @dudinlab.bsky.social
@embl.org @biology-unige.bsky.social @moorefound.bsky.social
August 7, 2025 at 6:22 PM
Reposted by Felix Mikus
gautamdey.bsky.social
Want to acquire #ExM images like this and help us understand the true extent of cytoskeletal diversity across the tree of life? This position might be for you!

embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

With @dudinlab.bsky.social
@embl.org @biology-unige.bsky.social @moorefound.bsky.social
August 7, 2025 at 6:12 PM
Reposted by Felix Mikus
cami-autorino.bsky.social
Happy to share that I defended my PhD this week!
✨✨It has been an amazing adventure full of learning, great science and incredible people here at @embl.org!✨✨
Looking forward to the next steps in my scientific journey
🔬🐟💛
If you haven't yet, check the preprint of my PhD research: bit.ly/45eBxOg
embldbunit.bsky.social EMBL DB unit @embldbunit.bsky.social · Jul 30
🎓Congratulations to Camilla Autorino, from the Petridou group @nicolettapetridou.bsky.social @embl.org who has just defended her PhD thesis titled 'A closed feedback between tissue phase transitions and morphogen gradients drives patterning dynamics in the zebrafish embryo' #DevelopmentalBiology
July 31, 2025 at 10:00 AM
Reposted by Felix Mikus
dudinlab.bsky.social
Such a pleasure to be co-organising the #Latsis Symposium this year with Guillermina !

Thanks to all the speakers & sponsors.

And all our teams members who helped make this a reality.

It just felt right.

#Science #WildCells #ProtistsOnSky #Cell #Biology #Biophysics #Behaviour
July 10, 2025 at 1:41 PM
Reposted by Felix Mikus
florianwollweber.bsky.social
After 5 amazing years @pilhoferlab.bsky.social I'm starting my lab @embl.org Grenoble this November embl.org/wollweber
We'll image Asgard archaea and many other strange microbes ( #archaeasky, #protistsonsky..) to understand eukaryogenesis
First job ad: #teamtomo scientist!🔬❄️ tinyurl.com/2rdu2ze6
June 27, 2025 at 10:58 AM
Reposted by Felix Mikus
wcratcliff.bsky.social
1/27 We have a new paper out! Turns out that snowflake yeast have been hiding a secret from us - they've evolved a (very!) crude circulatory system. Not with blood vessels or a heart, but through spontaneous fluid flows powered by their metabolism. 🧪🔬

www.science.org/doi/full/10....
June 24, 2025 at 4:52 PM
Reposted by Felix Mikus
jennaelliott.bsky.social
🧵 🧪 1/ Hi! I’m excited to share our latest work, now on arXiv:

Repulsive particle interactions at cellular interfaces enable selective information processing (arxiv.org/abs/2506.14739)

Where we explore how the physical properties of living systems can help cells process spatial information.
Sketch of membrane-enclosed compartment with particles on its surface, which interact with an adjacent structure
June 18, 2025 at 5:07 PM
Reposted by Felix Mikus
floravincent.bsky.social
Excited to share the lab's 1rst preprint! Rapid high-res immunofluorescence is now possible in cultured & environmental diatoms thanks to 4-fold expansion microscopy. A step-change for comparative cell biology in one of the most important phytoplankton groups on the planet 🥳
tinyurl.com/m9s5su7s 1/2
June 17, 2025 at 7:33 AM